• Journal of Pharmaceutical Investigation
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• v.34 no.4
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• pp.269-274
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• 2004

To enhance the solubility and stability of lansoprazole (LAN), new proton pump inhibitor, we were prepared various molar ratio of inclusion complex with $2-hydroxypropyl-{\beta}-cyclodextrin$ (HPCD) and organic alkali agent, meglumine (MEG). Inclusion complex formation of LAN with HPCD was investigated by Differential Scanning Calorimetry and X-ray diffractometry. The aqueous solubilities of inclusion complexes, and the stabilities of 1:4 and 1:5 inclusion complexes in aqueous solutions containing different concentrations of MEG were examined. The stability of 1:5 LAN-HPCD inclusion complex containing MEG, which was equaled to amount of LAN, was performed in 0.9% NaCl and 5% dextrose solution. The formation of inclusion complex of LAN with HPCD was $A_L$ type and the molar ratio of complex was 1:1. The stability constant was $41.557\;M^{-1}$. As molar ratio of LAN to HPCD was increased, solubility of inclusion complex was increased. 1:5 LAN-HPCD inclusion complex was more stable than 1:4 LAN-HPCD inclusion complex. And as contained MEG amount in LAN solution was increased, stability of 1:4 and 1:5 LAN-HPCD inclusion complexes was improved. Also stability of 1:5 LAN-HPCD-MEG inclusion complex in 0.9% NaCl solution and 5% dextrose solution was similar to it in water at room temperature, but it was unstable at $40^{\circ}C$.

• 한국연소학회:학술대회논문집
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• 2013.06a
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• pp.73-76
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• 2013

The inert gas dilution effect for the stability of a stratified propane premixed flame has been experimentally studied. The addition of inert gases to a stratified premixed flame, which used to be very stable without dilution, makes a flame unstable. The lower equivalence ratio on the outer premixed flame and the lower fuel flow rate through the inner nozzle were observed to be the more stable conditions for the stratified premixed flame with nitrogen or argon dilution. It has been interpreted with the flame structure change such as shift of stoichiometric ratio region in a flame.

• Journal of the Chungcheong Mathematical Society
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• v.36 no.1
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• pp.39-53
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• 2023

In this paper, we consider a delayed ratio-dependent predator-prey reaction-diffusion system with homogenous Neumann boundary conditions. We study the existence of nonnegative solutions and the stability of the nonnegative equilibria to the system. In particular, we provide a sufficient condition for the positive equilibrium to be globally asymptotically stable.

• Proceedings of the Korea Institute of Applied Superconductivity and Cryogenics Conference
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• 1999.02a
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• pp.61-64
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• 1999

Dry winding is generally adopted in superconducting coils of an UPS system. In these kinds of coils a quench is often initiated by a disturbance such as wire motion that generates a highly localized normal zone in a superconducting wire. To fabricate the stable coils, stability of the superconducting wire should be touched. In this paper, a model for a transient stability analysis of the wire is suggested. The influence of a local disturbance, cooling, an external field and a stabilizer to superconductor ratio on the wire stability is investigated and discussed.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.1
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• pp.174-182
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• 2007

In this paper, we study the influence of infection ratio on gradual reduction of drug dose for the five state HIV infection model that explicitly includes the population of the virus. We first compute all equilibrium points of the model and investigate the stabilities of them. As a result, a bifurcation diagram is obtained which shows a change in the equilibrium points, or in their stability properties, as the drug effect $\eta$ is varied from 0 to 1(alternatively, drug dose is changed from 1 to 0). Based on the bifurcation diagram, we show that the gradual reduction of drug dose can be applied for the treatment of AIDS patients. Moreover, we analyze the influence of the variation of infection ratio on the gradual reduction treatment. Computer simulation results are also presented to validate the proposed results.

• Journal of Welding and Joining
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• v.19 no.5
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• pp.486-491
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• 2001

The effect of S content in welding wires on spattering characteristics and droplet transfer phenomena was studied. In MAG welding using 80%Ar-$20%CO_2$ shielding gas, spattering characteristics and droplet transfer phenomena were varied with S content of wire. Sulfur addition in wire reduced surface tension of droplet and weld pool, and made arc more stable in MAG welding. With increasing S content, the spattering ratio and the ratio of large size spatter ($d{\geq}1.0mm$) were reduced in short circuit transfer mode. In spray transfer mode, spattering ratio, however was increased when sulfur was added more than 0.020wt.% because surface tension of droplets and weld pool was reduced too much even though arc stability was improved.

• 한국전산유체공학회:학술대회논문집
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• 2002.10a
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• pp.95-102
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• 2002

Studies of the numerical characteristics of implicit upwind schemes, such as upwind ADI, Line Gauss-Seidel(LGS) and Point Gauss-Seidel(LU) algorithms, for preconditioned Navier-Stokes equations ate performed. All the algorithms are expressed in approximate factorization form and Von Neumann stability analysis and convergence studies are made. Preconditioning is applied for efficient convergence at low Mach numbers and low Reynolds numbers. For high aspect ratio computations, the ADI and LGS algorithms show efficient and uniform convergence up to moderate aspect ratio if we adopt viscous preconditioning based on min- CFL/max- VNN time-step definition. The LU algorithm, on the other hand, shows serious deterioration in convergence rate as the grid aspect ratio increases. Computations for practical applications also verify these results.

• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.4
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• pp.135-143
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• 2013

In this study, we suggested effective countermeasure of biodiesel oxidation problems by investigating the oxidation degradation of biodiesels derived from variable resources and the level of oxidation stability of current distributing biodiesel blended fuels (2%) in Korea, and oxidation stability change according to storage time (for 3 month) and biodiesel blending ratio (2, 5, 7, 10%). By the composition analysis results of biodiesel from various resources which are possible to distribute in Korea, the biodiesel from animal fat has poor oxidation stability and cold performance, while the biodiesel from coconut and palm kernel which are considered as future potential raw material showed good oxidation stability and cold performance. The oxidation stability level of current distributing biodiesel blended fuels in Korea was excellent with showing over 30 hours (average 68 hours) stability, but the oxidation stability of the blended fuel with animal fat biodiesel having poor oxidation property (1.22 hours) was rapidly decreased to below 32 hours by mixing only 2%. Therefore, we have to pay attention to quality control of oxidation property, because the oxidation stability problem can be caused by increasing biodiesel blending ratio and diversifying raw materials those have worse property.

• Geomechanics and Engineering
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• v.23 no.3
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• pp.289-300
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• 2020

With the rapid development of the distributed strain sensing (DSS) technology, the strain becomes an alternative monitoring parameter to analyze slope stability conditions. Previous studies reveal that the horizontal strain measurements can be used to evaluate the deformation pattern and failure mechanism of soil slopes, but they fail to consider various influential factors. Regarding the horizontal strain as a key parameter, this study aims to investigate the stability condition of a locally loaded slope by adopting the variable-controlling method and conducting a strength reduction finite element analysis. The strain distributions and factors of safety in different conditions, such as slope ratio, soil strength parameters and loading locations, are investigated. The results demonstrate that the soil strain distribution is closely related to the slope stability condition. As the slope ratio increases, more tensile strains accumulate in the slope mass under surcharge loading. The cohesion and the friction angle of soil have exponential relationships with the strain parameters. They also display close relationships with the factors of safety. With an increasing distance from the slope edge to the loading position, the transition from slope instability to ultimate bearing capacity failure can be illustrated from the strain perspective.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.8
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• pp.116-121
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• 2001

The paper presents the dynamic characteristics of a rotor-bearing system supported by an actively controlled hydrodynamic journal bearing. The proportional. derivative and integral controls are adopted for the control algorithm to control the hydrodynamic journal bearing with an axial groove. Also, the cavitation algorithm implementing the Jakobsson-Floberg-Olsson boundary condition is adopted to predict cavitation regions in the fluid film more accurately than conventional analysis, which uses the Reynolds condition. The speed at onset of instability of a rotor-bearing system is increased by both proportional and derivative control of the bearing. The proportional control increases the stability threshold without affecting the whirl ratio. However, for the derivative control of the bearing, increase of stability threshold speed is accompanied by a parallel reduction of the whirl ratio. The integral control has no effect on stability characteristics of hydrodynamic journal bearing. The PD-control is more effective than proportional or derivative control. Results 7how the active control of bearing can be adopted for the stability improvement of a rotor-bearing system.