• Title/Summary/Keyword: Spray-dryer

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Artificial Neural Network Models in Prediction of the Moisture Content of a Spray Drying Process

  • Taylan, Osman;Haydar, Ali
    • Journal of the Korean Ceramic Society
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    • v.41 no.5
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    • pp.353-358
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    • 2004
  • Spray drying is a unique drying process for powder production. Spray dried product must be free-flowing in order to fill the pressing dies rapidly, especially in the ceramic production. The important powder characteristics are; the particle size distribu-tion and moisture content of the finished product that can be estimated and adjusted by the spray dryer operation, within limits, through regulation of atomizer and drying conditions. In order to estimate the moisture content of the resultant dried product, we modeled the control system of the drying process using two different Artificial Neural Network (ANN) approaches, namely the Back-Propagation Multiplayer Perceptron (BPMLP) algorithm and the Radial Basis Function (RBF) network. It was found out that the performance of both of the artificial neural network models were quite significant and the total testing error for the 100 data was 0.8 and 0.7 for the BPMLP algorithm and the RBF network respectively.

Simulation of effect of spray angle on the mixing effect in spray dryer absorber (분무건조 반응기에서 노즐 분사 각도에 따른 혼합효과의 전산 모사)

  • 송호철;김동주;함승주;박진원
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2002.04a
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    • pp.305-306
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    • 2002
  • 우리나라 폐기물 발생량은 1991년도까지는 연평균 8%의 증가를 보였으나 1992년 이후부터는 조금씩 감소하는 추세를 나타냈다. 폐기물 발생량의 감소요인은 배출원에서의 원천적인 감량화 노력과 함께 종량제 신시에 따른 쓰레기 분리수거 및 재활용율 제고 등에 따른 것이며, 특히 음식물 쓰레기 및 연탄재발생량의 감소가 크게 나타났다. 그러나 산업활동의 증가로 사업장 폐기물과 건축폐기물은 급증하는 추세를 보이고 있다. (중략)

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Improved Dissolution and Characterization of Solid Dispersed Atorvastatin Calcium (아토르바스타틴 칼슘 고체분산체의 특성화 및 용출율 개선)

  • Lee, Jun-Hee;Ku, Jeong;Park, Jung-Soo;Park, Jong-Hak;Ahn, Sik-Il;Mo, Jong-Hyun;Kim, Yun-Tae;Rhee, John-M.;Lee, Hai-Bang;Khang, Gil-Son
    • Journal of Pharmaceutical Investigation
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    • v.38 no.2
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    • pp.111-117
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    • 2008
  • To overcome the solubility of poorly water-soluble drug, the formation of solid dispersion using a spray-dryer with polymeric material, that can potentially enhance the dissolution rate extend of drug absorption was considered in this study. $Eudragit^{(R)}$ E100 as carrier for solid dispersion is acrylate copolymer that soluble in acidic buffer solutions (below pH 5.0). It was used to increase dissolution of atorvastatin calcium as a water-insoluble drug in acidic environments. In this study, a spray-dryer was used to prepare solid dispersion of atorvastatin calcium and $Eudragit^{(R)}$ E100 for purpose of improving the solubility of drug. Atorvastatin calcium and $Eudragit^{(R)}$ E100 were dissolved in ethanol and spray-dryed. DSC and XRD were used to analyze the crystallinity of the sample. It was found that atorvastatin calcium is amorphous in the $Eudragit^{(R)}$ E100 solid dispersion. FT-IR was used to analyze the salt formation by interaction between atorvastatin calcium and $Eudragit^{(R)}$ E100. Comparative dissolution study exhibited better dissolution characteristics than the commercial drug ($Lipitor^{(R)}$) as control. The dissolution rate of atorvastatin calcium was markedly increased in solid dispersion system in simulated gastric juice (pH 1.2). This study proposed that this solid dispersion system improved the bioavailability of poorly water-soluble atorvastatin calcium.

Prediction on the Stability of Spray-Dried Lactobacillus reuteri KUB-AC5 by Arrhenius Equation for Long-Term Storage

  • KORAKOCH HAMSUPO;SUKYAI PRAKIT;LOISEAU GERARD;NITISINPRASERT SUNEE;MONTET DIDIER;WANCHAITANAWONG PENKHAE
    • Journal of Microbiology and Biotechnology
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    • v.15 no.6
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    • pp.1178-1182
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    • 2005
  • Survival of thermotolerant Lactobacillus reuteri KUB-AC5 in $20\%$ (w/v) skim milk was found to be $11.3\%$ after spray drying by using a pilot scale spray dryer with inlet temperature at $170^{\circ}C$ and outlet temperature at $85^{\circ}C$. The ability of dried cell to produce antimicrobial activity was not affected by the spray drying. The model system for predicting viability of spray-dried L. reuteri KUB-AC5 during long-term storage was established, based on the Arrhenius equation, and verified by experimental data, because the viability of cells during storage can be correlated with storage temperature. The viability during storage at $30^{\circ}C$ declined more rapidly than that storage at $4^{\circ}C$.

A Fuzzy Modeling Approach for a Spray Drying Production Process

  • Aburas Hani Mohammad A.
    • Journal of the Korean Ceramic Society
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    • v.41 no.12 s.271
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    • pp.873-879
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    • 2004
  • In all major industries ranging from powder industries and advanced ceramics, to the food and pharmaceutical manufacture powder industries, the main production process is the spray dryers. In this paper, a systematic approach is used and six rules are obtained for the basis of the fuzzy model. A fuzzy model is based on the past behavior of the target system and expected to be able to reproduce the behavior of the target system. The output of the developed fuzzy model shows, graphically and statistically, a high level of face validity. Therefore, it is concluded that the developed fuzzy model mimics the actual process and can be considered, with confidence, as a reliable model to study, analyze, and improve the existing process.

Atomization Chracteristics of Spinning Disk for Spray Dry (분무건조를 위한 회전원판의 미립화 특성에 관한 연구)

  • Oh, Jae-Geon;Park, Ki-Ho;Park, Jun-Taek;Lim, Sang-Gun
    • Journal of the Korean Society of Industry Convergence
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    • v.3 no.4
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    • pp.353-360
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    • 2000
  • The purpose of this research is to find the fundamental data for the design and optimum operation condition for the disk atomization comparing the atomization characteristics of the modified straight vane type disk atomizer and the cup type atomizer widely used in the field of spray dry. First, the experimental comparison of the characteristics of $Na_2SO_4$ atomization has been carried out using the cup type disk atomizer and the three kinds of vane type atomization designed specially for the experiment. After the comparison of the experimental data of the $Na_2SO_4$ and raw milk have been conducted using vane type atomizer.

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Experimental Study on Water Absorption and Drying Characteristics of Various Fabrics using IR Camera (열화상카메라를 이용한 직물의 물 흡수 및 건조 특성에 대한 실험 연구)

  • Jeongbae Kim
    • Journal of ILASS-Korea
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    • v.28 no.1
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    • pp.10-15
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    • 2023
  • Recently, various types of towels and dishcloth dryer products are being widely distributed in Korea. Evaluation methods for water absorption properties of various fabrics have been developed, and there are many studies using them. This study newly intended that whether it is possible to obtain data that can quantitatively analyze the water absorption characteristics of various fabrics, to show the correlation between the water absorption height and the amount of water (water holdup) absorbed, and to experimentally suggest the applicability to evaluate the drying capacity of towel dryer using IR camera. Through these experiments, it was confirmed that quantitative data on the water absorption height of various fabrics can be measured using an IR camera and can be clearly applied to the performance evaluation of actual products.

Optimization of spray drying condition of Sikhye using response surface methodology (반응표면분석법을 이용한 식혜의 최적 분무건조 조건)

  • Kim, Gi Chang;Jo, In Hee;Kim, Gyoung Mi;Choi, Song Yi;Kim, Jin Sook
    • Food Science and Preservation
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    • v.22 no.5
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    • pp.683-689
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    • 2015
  • Response surface methodology (RSM) is a statistical procedure frequently used for optimization studies. The purpose of this study was to determine the optimal spray drying condition for manufacturing Sikhye powder using RSM. Independent variables included the additive contents of maltodextrin (MD), inlet temperature, and velocity of sample feed velocity. The dependent variables were water uptake (g), solubility (%) and particle size (${\mu}m$). Regression models describing the changes of water uptake (g), solubility (%) and particle size (${\mu}m$) with respect to the independent variables were statistically significant with coefficients of determination, $R^2$, greater than 0.9. The results indicated that the inlet temperature of the spray dryer was the most important independent variable that affected the water uptake (g), while the additive content of MD and the sample feed velocity had maximum effects on the solubility (%) and particle size (${\mu}m$) of the Sikhye powder, respectively. The optimum final product was expected to have the lowest possible water uptake (g) and particle size (${\mu}m$) but the highest possible solubility (%). In conclusion, the best spray drying conditions were as follows: additive MD content, 22%; inlet temperature, $140^{\circ}C$ ; and spray dryer sample feed velocity, 51 mL/min.

EXPERIMENTAL STUDY OF OPTIMUM DRYING CONDITION IN THE PROCESS OF SPRAY FREEZE DRYING (분무동결건조과정의 최적 건조조건 도출에 관한 실험적 연구)

  • Park, Kyong-Won;Song, Chan-Ho;Song, Chi-Sung
    • Proceedings of the SAREK Conference
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    • 2008.06a
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    • pp.1321-1326
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    • 2008
  • A study on the heat and mass transfer for the drying time in spray freezing drying process was experimentally presented in this paper. A spray freezing dryer for the production of an inhalable powder medicine is developed and an albumin solution as protein specimen is adopted. The freeze-drying for the albumin solution is tested in three different height of the particles piled up in a tray such as 2 mm, 5 mm, 7 mm, and the drying time is estimated as 10 h, 15 h, 22 h. From this results, the correlation is suggested and the drying time with various height of the particles piled up in a tray can be estimated. The assessment on the drying time is conducted thought a microbalance and the rate of water content is measured. The results based on temperature and weight are compared. The difference of the results happens due to the heat transfer from the lateral side of the vial. It is thought that the better estimation in drying time can be predicted by considering the heat transfer effect.

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