• Korean Journal of Pharmacognosy
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• v.45 no.2
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• pp.113-120
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• 2014

Generally, Gwakhyangjeonggi-san has been used for treatment of diarrhea-predominant irritable bowel syndrome. In this study, an ultra-performance liquid chromatography-electrospray ionization-mass spectrometer method was established for the simultaneous quantification of marker compounds 1-20 in Gwakhyangjeonggi-san water extract. All analytes were separated by gradient elution using two mobile phases on a UPLC BEH $C_{18}$ ($100{\times}2.1mm$, $1.7{\mu}m$) column and maintained at $45^{\circ}C$. The injection volume was $2.0{\mu}L$ and the flow rate was 0.3 mL/min with detection at mass spectrometer. Regression equations of the compounds 1-20 were acquired with $r^2$ values ${\geq}0.9950$. The values of limit of detection and quantification of all analytes were 0.01-2.79 ng/mL and 0.03-8.37 ng/mL, respectively. The amounts of the compounds 1-20 in Gwakhyangjeonggi-san water extract were not detected $-3,236.67{\mu}g/g$. The established LC-MS/MS methods will be valuable to improve quality control of traditional herbal formula, Gwakhyangjeonggi-san.

• Journal of Radiation Protection and Research
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• v.35 no.3
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• pp.105-110
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• 2010

Using N-type HPGe gamma spectrometer, uranium analysis technique of soil sample is developed where the chemical preprocessing is not a necessity. The results of uranium activities using the method presented in this paper were compared with those results with conventional alpha spectrometer and two results were similar from within uncertainty range. Therefore, this new method will be applied in uranium activity analysis of soil sample.

• Bulletin of the Korean Chemical Society
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• v.26 no.1
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• pp.115-118
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• 2005

The miniaturized NIR (Near-infrared) spectrometer has been utilized for the determination of water content (1-19% range) in ethanol that is the most popular organic solvent in pharmaceutical industries. It has many potential capabilities that can replace the conventional analyzers especially for the on-line measurement since it is compact, versatile and cost-effective. By using two dimensional (2D) correlation spectroscopy, it was preliminarily investigated to find any unforeseen spectral distortion among the spectra collected from the miniaturized spectrometer. The 2D study revealed that the spectral variation clearly followed the variation of water concentration without any spectral distortion or abnormality. PLS (Partial Least Squares) was employed to build the calibration model and the resulting prediction performance was acceptable and stable over several days. Even though the miniaturized NIR system was evaluated to fairly simple chemical matrix, the overall study demonstrates the sufficient feasibility for diverse practical and industrial applications.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.586-586
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• 2012

The vuv spectrometer for ITER main plasma measurement is designed as a five-channel spectral system. To develop and verify the design, a two-channel prototype system was fabricated with No. 3 (14.4-31.8 nm) and No. 4 (29.0-60.0 nm) among the five channels. For test of the prototype system, a hollow cathode lamp is used as a light source. The system is composed of a collimating mirror to collect the light from source to slit, and two holographic diffraction gratings with toroidal geometry to diffract and also to collimate the light from the common slit to detectors. The overall system performance was verified by comparing the measured spectral resolutions with the calculated spectral resolutions. And we also have developed liquid jet target system. This study is about a neutron generator, which is designed to overcome many of the limitations of traditional beam-target neutron generators by utilizing a liquid target. One of the most critical aspects of the beam-target neutron generator is the target integrity under the beam exposure. A liquid target can be a good solution to overcome damage to the target such as target erosion and depletion of hydrogen isotopes in the active layer, especially for the ones operating at high neutron fluxes and maintained relatively thin with no need for water cooling. In this study, liquid target containing hydrogen has been developed and tested.

• Analytical Science and Technology
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• v.11 no.6
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• pp.448-451
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• 1998

The feasibility of using FT-NIR (Fourier Transform Near Infrared) spectrometer to measure NaOH, $Na_2CO_3$ and $Na_2S$ concentration in a naphtha cracking process, and an outline of the method development to identify spectral feature of the hydroxide whose band is overlapped by a strong water absorption were demonstrated. For measuring NaOH, $Na_2CO_3$ and $Na_2S$, FT-NIR spectrometer is a rapid and possible alternative to the current titration method with a standard deviation of 0.1.

• Korean Journal of Optics and Photonics
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• v.24 no.3
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• pp.143-147
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• 2013

A Raman spectrometer is essential for analyzing the characteristics of graphene. The commercial micro-Raman spectrometer is useful for measuring small areas, but due to the small measuring area, it has limited use in industry, as a sampling measure. This paper suggests a Raman spectrometer able to get a large area image of graphene. By using this image, we can get information on defects and on the presence of graphene. Therefore, this equipment can be used for quality assessment for production of graphene.

• Current Optics and Photonics
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• v.1 no.4
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• pp.295-307
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• 2017

An innovative system for the alternative continuous wide spectral spatial heterodyne spectrometer (ACWS-SHS) is proposed. The relationship between the ACWS-SHS and the wide spectral spatial heterodyne spectrometer (WS-SHS) at the resolution limit, the spectral range, the grating diffraction efficiency and the interference fringes contrast ratio has been analyzed theoretically. Through the comparison of the theoretical analysis and simulation results, it is found that the two systems for the WS-SHS and the ACWS-SHS have the same resolution limit and spectral range, which are ${\delta}{\sigma}$ and ${\sigma}_{01}$, while in the ACWS-SHS system the critical diffraction efficiency of echelle grating is 68.39% and the critical contrast ratio of interference fringes is 0.4135, which is much better than the performance of the WS-SHS system. Therefore, the ACWS-SHS reduces the high requirements for the precision of equipment and expands the application field of SHS effectively.

• Journal of the Korean Chemical Society
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• v.40 no.12
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• pp.719-723
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• 1996

An inverse photoemission spectrometer has been built and tested to study the unoccupied electron energy states of solid surfaces. It consists of a low energy electron gun and a band pass photon detector in an ultra-high vacuum chamber. The electron ray tracing simulation and current measurement of the electron gun show a good focus and a high flux of electron current. The overall resolution of the spectrometer is 0.74 eV and the sensitivity of the photon detector is about 10 counts/$sec{\cdot}{\mu}A.$ As a test experiment, the inverse photoemission spectra of a Ge(111) sample is in good agreement with the theoretical result.

• Bulletin of the Korean Chemical Society
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• v.34 no.1
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• pp.207-210
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• 2013

We report the construction of a MALDI imaging mass spectrometer equipped with a specially designed laser focusing lens, a compact aspherical singlet lens, that obtains a high-lateral imaging resolution in the microprobe mode. The lens is specially designed to focus the ionization laser (${\lambda}$ = 355 nm) down to a $1{\mu}m$ diameter with a long working distance of 34.5 mm. With the lens being perpendicular to the sample surface and sharing the optical axis with the ion path, the imaging mass spectrometer achieved an imaging resolution of as good as $5{\mu}m$ along with a high detection sensitivity of 100 fmol for peptides. The mass resolution was about 900 (m/${\Delta}m$) in the linear TOF mode. The high-resolution capability of this instrument will provide a new research opportunity for label-free imaging studies of various samples including tissues and biochips, even for the study at a single cell level in the future.

• Publications of The Korean Astronomical Society
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• v.21 no.2
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• pp.21-26
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• 2006

A Korean team (Korea Astronomy and Space Science Institute, Korea Basic Science Institute, and Kyung Hee University) takes part in an international cooperation project called CIBER (Cosmic Infrared Background ExpeRiment), which has begun with Jet Propulsion Laboratory (JPL) in USA and Institute of Space and Astronautical Science (ISAS) in Japan. CIBER is a rocket-borne instrument, of which the scientific goal is to measure the cosmic near-infrared extra-galactic background to search for signatures of primordial galaxy formation. CIBER consists of a wide-field two-color camera, a low-resolution absolute spectrometer, and a high-resolution narrow-band imaging spectrometer. The Korean team is in charge of the ground support electronics and manufacturing of optical parts of the narrow-band spectrometer, which will provide excellent opportunities for science and technology to Korean infrared groups.