• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.71.2-71.2
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• 2021

Using multi-epoch spectra of active galactic nuclei (AGN) obtained from the Sloan Digital Sky Survey, we identify 16 spectrally variable sources, for which the spectral shapes of broad emission lines significantly vary with a time scale of yrs. Out of them, 3 AGNs are already known as changing-look (CL) AGNs by previous studies. 6 AGNs are newly identified as CL AGNs from our study. A majority of these AGNs are relatively faint and their variability in the continuum is small, which may explain their non-detection in the previous studies. 7 sources are known as binary AGN candidates based on the systematic velocity offset between broad emission lines and narrow emission lines. For those sources and 3 CL AGNs, we find that the peak of broad emission lines had been shifted up to a few thousands km/s for ~10 years, implying that those can be promising candidates for pc-scale binary AGNs or recoiling black holes. We plan to conduct multiwavelength follow-up studies to nail down the physical origin of the velocity shift.

• Geotechnical Engineering
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• v.13 no.3
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• pp.53-62
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• 1997

Analytical studies were conducted to develop the Spectral-Analysis-of-Surface-Waves (SASW) method for underwater use. For the precise estimation of the in-situ soil stiffness profile from SASW measurements, it is essential to determine economical and reasonable theoretical dispersion curves reflecting various experimental conditions. In this paper, therefore, analytical methods are mainly discussed, which were developed to determine theoretical dispersion curves of surface waves propagated along the soil-water interface. Application of the analytical methods is then illustrated by an example involving estimation of a stiffness profile through a forward modeling process of SASW measurements. Applicabilities of the SASW method as well as the developed analytical methods are evaluated, respectively, from the example.

• Journal of the Ergonomics Society of Korea
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• v.22 no.3
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• pp.75-91
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• 2003

Evaluation of repetitiveness for hand-intensive tasks is essential to determine the level of risk for upper-extremity musculoskeletal disorders at the workplace. Many measures and methods have been introduced for repetitiveness assessment: however, our understanding of the differences among these measures and methods is lacking. The present study compared the repetitiveness measures and measurement/analysis methods to help practitioners apply the proper repetitiveness assessment methodology in the workplace. By reviewing 51 studies of repetitiveness assessment, measures and corresponding measurement/analysis methods were surveyed. Of the repetitiveness measures, two types of dimensions (frequency and time) and corresponding types of analysis scopes were identified. According to the dimensional and analysis-scope types. the repetitiveness measures were categorized and then the surveyed studies were counted for each measure. It is identified that frequency measures have used 2.7 times higher than time measures and the frequency of wrist motions has been most frequently used in repetitiveness assessment. Furthermore, the measurement methods were categorized into objective and subjective methods, and the analysis methods into statistical and spectral methods. Lastly, eight factors (accuracy, reliability. sensitivity. efficiency. ease of use. applicability. interference. and robustness) were listed to be considered in selecting the appropriate assessment methodology.

• Journal of Electrochemical Science and Technology
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• v.8 no.3
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• pp.222-235
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• 2017

First, in this study, the inhibition efficiencies of metal complexes with Cu(II), Ni(II) and Zn(II) of STSC ligand for corrosion control of mild steel in oilfield formation water were investigated. The IEs for a mixture of 500 ppm STSC and 5 ppm metal ion ($Cu^{+2}$, $Ni^{+2}$, $Zn^{+2}$) were found to be 88.77, 87.96 and 85.13 %, respectively. The results were obtained from the electrochemical techniques such as open circuit potential, linear and tafel polarization methods. The polarization studies have showed that all used Schiff base metal complexes are anodic inhibitors. The protective film has been analyzed by FTIR technique. Also, to detect the presence of the iron-inhibitor complex, UV-Visible spectral analysis technique was used. The inhibitive effect was attributed to the formation of insoluble complex adsorbed on the mild steel surface and the adsorption process follows Langmuir adsorption isotherm. The surface morphology has been analyzed by SEM. Secondly, the computational studies of the ligand and its metal complexes were performed using DFT (B3LYP) method with the $6-311G^{{\ast}{\ast}}$ basis set. Finally, it is found that the experimental results were closely related to theoretical ones.

• BMB Reports
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• v.45 no.12
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• pp.736-741
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• 2012

Certain members of the cytochromes P450 superfamily metabolize polyunsaturated long-chain fatty acids to several classes of oxygenated metabolites. An approach based on in silico analysis predicted that Streptomyces peucetius CYP107N3 might be a fatty acid-metabolizing enzyme, showing high homology with epoxidase enzymes. Homology modeling and docking studies of CYP107N3 showed that oleic acid can fit directly into the active site pocket of the double bond of oleic acid within optimum distance of $4.6{\AA}$ from the Fe. In order to confirm the epoxidation activity proposed by in silico analysis, a gene coding CYP107N3 was expressed in Escherichia coli. The purified CYP107N3 was shown to catalyze $C_9-C_{10}$ epoxidation of oleic acid in vitro to 9,10-epoxy stearic acid confirmed by ESI-MS, HPLC-MS and GC-MS spectral analysis.

• Korean Journal of Pharmacognosy
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• v.20 no.1
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• pp.13-20
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• 1989

In continuation of our studies on essential oils of Angelica genus(Umbelliferae), We report on the components of essential oils obtained from the root of Angelica tenuissima Nakai(藁子). Oils were obtained from the dried roots by steam distillation and fractionated by column chromatography. Each isolate or fraction was identified by GC, GC-MS and spectral analysis. Essential oils of the root of A. tenuissima(Gaoben) were found to contain $\alpha-pinene,\;camphene,\;\beta-pinene,\;myrcene,\;\alpha-phellandrene,\;\Delta-3-carene,\;p-cymene,\;limonene,\;\gamma-terpinene,\;terpinolene,\;4-vinylguauacol,\;\gamma-elemene$, one aromatic compound, three unidentified sesquiterpene alcohols, butylidenephthalide, senkyunolide and Z-ligustilide which was the most abundant compound comprising 75% of the whole oil. Also butylphthalide and hydroxybutylidenephalide were tentatively identified.

• Phonetics and Speech Sciences
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• v.3 no.3
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• pp.19-26
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• 2011

Previous laboratory studies have shown that prosodic structures are encoded in the modulations of phonetic patterns of speech including suprasegmental as well as segmental features. Drawing on a prosodically annotated large-scale speech data from the Buckeye corpus of conversational speech of American English, the current study first evaluated the reliability of prosody annotation by a large number of ordinary listeners and later examined whether and how prosodic prominence influences the phonetic realization of multiple acoustic parameters in everyday conversational speech. The results showed that all the measures of acoustic parameters including pitch, loudness, duration, and spectral balance are increased when heard as prominent. These findings suggest that prosodic prominence enhances the phonetic characteristics of the acoustic parameters. The results also showed that the degree of phonetic enhancement vary depending on the types of the acoustic parameters. With respect to the formant structure, the findings from the present study more consistently support Sonority Expansion Hypothesis than Hyperarticulation Hypothesis, showing that the lexically stressed vowels are hyperarticulated only when hyperarticulation does not interfere with sonority expansion. Taken all into account, the present study showed that prosodic prominence modulates the phonetic realization of the acoustic parameters to the direction of the phonetic strengthening in everyday conversational speech and ordinary listeners are attentive to such phonetic variation associated with prosody in speech perception. However, the present study also showed that in everyday conversational speech there is no single dominant acoustic measure signaling prosodic prominence and listeners must attend to such small acoustic variation or integrate acoustic information from multiple acoustic parameters in prosody perception.

• Journal of the Korean Chemical Society
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• v.55 no.6
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• pp.960-968
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• 2011

A series of isonicotinyl hydrazones and their 4-thiazolidinones have been synthesized by condensation of isonicotinic acid hydrazide with various aromatic aldehydes to yield Schiff's bases, followed by the cyclocondensation of Schiff's bases with 2-mercaptoacetic acid to yield their 4-thiazolidinones. The synthesized compounds have been characterized by their elemental, analytical and spectral studies. All these compounds were evaluated for their invitro antimicrobial activity against a spectrum of non-resistant and resistant microbial organisms. These studies proved that compounds 5e,i against B. subtilis; 5e,f,h against B. anthracis; 5g,i against S. aureus showed good activity at lower concentrations. Compounds 5d-5i displayed significant activity against resistant strain of K. pneumonia with minimum inhibitory potency in the concentration range of 2-16 ug/ml.

• Annals of Clinical Neurophysiology
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• v.22 no.2
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• pp.82-91
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• 2020

Electroencephalography (EEG) produces time-series data of neural oscillations in the brain, and is one of the most commonly used methods for investigating both normal brain functions and brain disorders. Quantitative EEG analysis enables identification of frequencies and brain activity that are activated or impaired. With studies on the structural and functional networks of the brain, the concept of the brain as a complex network has been fundamental to understand normal brain functions and the pathophysiology of various neurological disorders. Functional connectivity is a measure of neural synchrony in the brain network that refers to the statistical interdependency between neural oscillations over time. In this review, we first discuss the basic methods of EEG analysis, including preprocessing, spectral analysis, and functional-connectivity and graph-theory measures. We then review previous EEG studies of brain network characterization in several neurological disorders, including epilepsy, Alzheimer's disease, dementia with Lewy bodies, and idiopathic rapid eye movement sleep behavior disorder. Identifying the EEG-based network characteristics might improve the understanding of disease processes and aid the development of novel therapeutic approaches for various neurological disorders.

• Journal of the Korean Chemical Society
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• v.57 no.5
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• pp.574-590
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• 2013

A new solid complexes of Ti(IV), Y(III) and Ce(IV) have been synthesized with ofloxacin. The formulae and structure of the complexes have been proposed in the light of analytical, spectral ($^1H$ NMR, IR and UV-Visible), magnetic, molar conductivities and thermal studies. The complexes are soluble in DMSO-$d_6$ and DMF. The measured molar conductance values indicate that, the three complexes are electrolyte in nature. The results support the formation of the complexes and indicated that ofloxacin reacts as a bidentate ligand chelate to the metal ion through the pyridone oxygen and one carboxylato oxygen. The kinetic parameters of thermogravimetric and its differential have been evaluated by using Coats Redfern (CR) and Horowitz-Metzeger (HM) methods. The thermodynamic data reflect the thermal stability for all complexes. The metal- ligand binding of the Ti(IV), Y(III) and Ce(IV) complexes is predicted using density funcational theory at the B3LYP-CEP-31G level of theory and total energy, dipole moment estimation of different Ti(IV), Y(III) and Ce(IV) ofloxacin structures. The biological activities of the ofloxacin, inorganic salts and their metal complexes were assayed against different bacterial species.