• Bulletin of the Korean Chemical Society
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• 제30권11호
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• pp.2535-2541
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• 2009

Prebiotic isomaltooligosaccharide preparations contain $\alpha$-D-glucooligosaccharides comprising isomaltooligosaccharides (IMOs) and non-prebiotic maltooligosaccharides (MOs). They are both glucose oligosaccharides characterized by their degree of polymerization (DP) value (from 2 to $\sim$10), linkages types and positions (IMOs: $\alpha$-(1$\rightarrow$2, 3, 6 and in a lower proportion internal 1$\rightarrow$4) linkages, MOs: α-(1$\rightarrow$4) linkages). Their structure is the key factor for their prebiotic potential. In order to determine and elucidate the exact structure of unknown IMOs and MOs, unambiguous assignments of $^{13}C$ and $^1H$ chemical shifts of commercial standards, representative of IMOs and MOs diversity, have been determined using optimized standard one and two-dimensional experiments such as $^1H$ NMR, $^{13}C$ NMR, APT and ${^1}H-{^1}H$ COSY, TOCSY, NOESY and <$^1H-{^{13}}C$ heteronuclear HSQC, HSQC-TOCSY, and HMBC. Here we point out the differential effect of substitution by a glucose residue at different positions on chemical shifts of anomeric as well as ring carbons together with the effect of the reducing end configuration for low DP oligosaccharides and diasteroisotopic effect for H-6 protons. From this study, structural $^{13}C$ specific spectral features can be identified as tools for structural analysis of isomaltooligosaccharides.

• Bulletin of the Korean Chemical Society
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• 제30권11호
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• pp.2595-2602
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• 2009

Hexamer cluster of N,N-dimethylformamide(DMF) based on the crystal structure was investigated for the equilibrium structure, the stabilization energies, and the vibrational properties in the density functional force field. The geometry (point group $C_i$) of fully optimized hexamer clustered DMF shows quite close similarity to the crystal structure weakly intermolecular hydrogen bonded each other. Stretching force constants for intermolecular hydrogen bonded methyl and formyl hydrogen atoms with nearby oxygen atom, methyl C–H${\cdots}$O and formyl C–H${\cdots}$O, were obtained in 0.055 $\sim$ 0.11 and $\sim$ 0.081 mdyn/$\AA$, respectively. In-plane bending force constants for hydrogen bonded methyl hydrogen atoms were in 0.25 $\sim$ 0.33, and for formyl hydrogen $\sim$ 0.55 mdynÅ. Torsion force constants through hydrogen bonding for methyl hydrogen atoms were in 0.038 $\sim$ 0.089, and for formyl hydrogen atom $\sim$ 0.095 mdynÅ. Calculated Raman and infrared spectral features of single and hexamer cluster represent well the experimental spectra of DMF obtained in the liquid state. Noncoincidence between IR and Raman frequency positions of stretching C=O, formyl C–H and other several modes was interpreted in terms of the intermolecular vibrational coupling in the condensed phase.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
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• pp.426-428
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• 2003

Optical and microwave remote sensing data have been widely used in land cover and land use classification. Thanks to the spectral absorption characteristics of ground object in visible and near infrared region, optical data enables to extract different land cover types according to their material composition like water body, vegetation cover or bare land. On the other hand, microwave sensor receives backscatter radiance which contains information on surface roughness, object density and their 3-D structure that are very important complementary information to interpret land use and land cover. Separate use of these data have brought many successful results in practice. However, the accuracy of the land use / land cover established by this methodology still has some problems. One of the way to improve accuracy of the land use / land cover classification is just combination of both optical and microwave data in analysis. In this paper for the research, the author used LANDSAT TM scene 127/45 acquired on October 21, 1992, JERS-1 SAR scene 119/265 acquired on October 27, 1992 and aerial photographs taken on October 21, 1992. The study area has been selected in Hanoi City and surrounding area, Vietnam. This is a flat agricultural area with various land use types as water rice, secondary crops like maize, cassava, vegetables cultivation as cucumber, tomato etc. mixed with human settlement and some manufacture facilities as brick and ceramic factories. The use of only optical or microwave data could result in misclassification among some land use features as settlement and vegetables cultivation using frame stages. By combination of multitemporal JERS-1 SAR and TM data these errors have been eliminated so that accuracy of the final land use / land cover map has been improved. The paper describes a methodology for data combination and presents results achieved by the proposed approach.

• Journal of Photoscience
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• 제9권3호
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• pp.45-48
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• 2002

Microbial rhodopsins, photoactive 7-transmembrane helix proteins that use retinal as their chromophore, were observed initially in the Archaea and appeared to be restricted to extreme halophilic environments. Our understanding of the abundance and diversity of this family has been radically transformed by findings over the past three years. Genome sequencing of cultivated microbes as well as environmental genomics have unexpectedly revealed archaeal rhodopsin homologs in the other two domains of life as well, namely Bacteria and Eucarya. Organisms containing these homologs inhabit such diverse environments as salt flats, soil, freshwater, and surface and deep ocean waters, and they comprise a broad phylogenetic range of microbial life, including haloarchaea, proteobacteria, cyanobacteria, fungi, and algae. Analysis of the new microbial rhodopsins and their expression and structural and functional characterization reveal that they fulfill both ion transport and sensory functions in various organisms, and use a variety of signaling mechanisms. We have obtained the first crystallographic structure for a photosensory member of this family, the phototaxis receptor sensory rhodopsin II (SRII, also known as phoborhodopsin) that mediates blue-light avoidance by the haloarchaeon Natronobacterium pharaonis. The structure obtained from x-ray diffraction of 3D crystals prepared in a cubic lipid phase reveals key features responsible for its spectral tuning and its sensory function. The mechanism of SRII signaling fits a unified model for transport and signaling in this widespread family of phototransducers.

• Annals of Clinical Neurophysiology
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• 제3권2호
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• pp.128-135
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• 2001

Background : Tremor is uncommon manifestation of stroke. Therefore a few cases have been reported until now. There is still uncertainty about the characteristics of post-stroke tremor. Furthermore the pathogenesis and responsible structures of post-stroke tremor are not precisely known. We have recently experienced 34 cases of post-stroke tremor for the past 6 years. We analysed the clinical features and electrophysiologic findings of post-stroke tremor to evaluate the general characteristics and to analogize the possible pathogenetic mechanisms of post-stroke tremor. Methods : The clinical characteristics of post-stroke tremor were summarized in according to the onset time, involved body parts, types, tremor frequencies, neuroradiologic findings, and associated symptoms. The tremor frequencies were recorded by using a gyroscope. The spectral analysis of tremor frequencies were done automatically with Motus I soft ware. Results : Tremor onset were remarkably varied. Some patients showed a tremor appearing at the onset of a stroke and other patients showed delayed-onset tremor 10 years after a stroke. Tremor frequencies were also much varied. The range of hand tremor frequencies were from 1.5 to 12 Hz. Lesions were found in 31 cases(infarction 27, hemorrhage 4) on neuroimaging. In the cases of cerebral infarctions, 7 cases showed multiple small vessel diseases and 20 cases showed cerebral vessel lesions. The most commonly involved cerebral vessel lesion was the middle cerebral artery territory Several different clinical patterns of post-stroke tremor were identified. Conclusions : There are some evidences from the data summarized here to suggest that several pathogenetic mechanisms including central oscillators could be involved for the development of tremors and that tremor generating neural circuits could be more complex than previously suggested neural circuits.

• 대한원격탐사학회지
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• 제21권1호
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• pp.91-98
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• 2005

On board satellite magnetometer measures all possible magnetic components, such as the core and crustal components from the inner Earth, and magnetospheric, ionospheric and' its coupled components from the outer Earth. Due to its dipole and non-dipole features, separation of the respective component from the measurements is most difficult unless the comprehensive knowledge of each field characteristics and the consequent modeling methods are solidly constructed. Especially, regional long wavelength magnetic signals of the crust are strongly masked by the main field and dynamic external field and hence difficult to isolate in the satellite measurements. In particular, the un-modeled effects of the strong auroral external fields and the complicated behavior of the core field near the geomagnetic poles conspire to greatly reduce the crustal magnetic signal-to-noise ratio in the polar region relative to the rest of the Earth. We can, however, use spectral correlation theory to filter the static lithospheric and core field components from the dynamic external field effects that are closely related to the geomagnetic storms affecting ionospheric current disturbances. To help isolate regional lithospheric anomalies from core field components, the correlations between CHAMP magnetic anomalies and the pseudo-magnetic effects inferred from satellite gravity-derived crustal thickness variations can also be exploited, Isolation of long wavelengths resulted from the respective source is the key to understand and improve the models of the external magnetic components as well as of the lower crustal structures. We expect to model the external field variations that might also be affected by a sudden upheaval like tsunami by using our algorithm after isolating any internal field components.

• 한국음향학회지
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• 제38권5호
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• pp.568-573
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• 2019

폐질환 진단에서 청진은 다른 진단 방식에 비해 단순하고, 폐음을 이용하여 폐질환 환자식별뿐 아니라 폐음과 관련된 질병을 예측할 수 있다. 따라서 본 논문에서는 다양한 합성곱 신경방 방식을 기반으로 폐음을 이용하여 폐질환 환자를 식별하고, 소리특성에 따른 폐음을 분류하여 각 신경망 방식의 분류 성능을 비교한다. 먼저 폐질환 소견을 갖는 흉부 영역에서 단채널 폐음 녹음기기를 이용하여 폐음 데이터를 수집하고, 수집된 시간축 신호를 스펙트럼 형태의 특징값으로 추출하여 각 분류 신경망 방식에 적용한다. 폐 사운드 분류 방식으로는 일반적인 합성곱 신경망, 병렬 구조, 잔류학습이 적용된 구조의 합성곱 신경망을 사용하고 실험을 통해 각 신경망 모델의 폐음 분류 성능을 비교한다.

• 지구물리
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• 제9권2호
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• pp.135-145
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• 2006

미국 해양대기청의 CCM3 기후모델을 이용하여 마지막최대빙하기 (Last Glacial Maximum(LGM)의 기온 및 물. 이용된 수치모델의 수평해상도는 약 75 km로 비교적 상세한 기후 기작들이 표현된다. LGM 실험은 CLIMAP 프로젝트에서 복원된 표층해수가 경계조건으로 이용되었으며 , LGM에 낮았던 대기 이산화탄소농도(200 pm) 이 적용되었고, 대륙빙하를 포함한 LGM 지표지형이 표현되었다 . LGM 경계조건하에서 전구온도는 겨울철 6.1도 여름철 5.6도 그리고 연평균 6도정도 감소한 것으로 시뮬레이션 된다 . 표층 기온의 감소는 14% 감소하고 여름에 17% 그리고 연간 13% 감소한다. 하지만, 미국, 남부유럽, 동아프리카, 남아메리카 등은 겨울에 현재보다 더 습하게 나타나며 , 캐나다 와 중동 지방은 여름철에 습윤하게 시뮬레이션 된다 . 이런 결과들은 호수면 변화기록으로부터 복원한 고기후 프락시 물수지 자료들과도 대체로 잘 일치한다 . 전체적으로 고해상도 기후모델은 지상에서 나타나는 세부적인 특징들을 잘 재현해내고 있다 .

• International Journal of Oral Biology
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• 제46권3호
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• pp.105-110
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• 2021

The physicochemical properties of crystalline titanium dioxide nanoparticles (TiO₂ NPs) were investigated by comparing amorphous (amTiO₂), anatase (aTiO₂), metaphase of anatase-rutile (arTiO₂), and rutile (rTiO₂) NPs, which were prepared at various calcination temperatures (100℃, 400℃, 600℃, and 900℃). X-ray diffraction (XRD) and scanning electron microscopy (SEM) analyses confirmed that the phase-transformed TiO₂ had the characteristic features of crystallinity and average size. The surface chemical properties of the crystalline phases were different in the spectral analysis. As anatase transformed to the rutile phase, the band of the hydroxyl group at 3,600-3,100 cm^-1 decreased gradually, as assessed using Fourier transform infrared spectroscopy (FT-IR). For ultraviolet-visible (UV-Vis) spectra, the maximum absorbance of anatase TiO₂ NPs at 309 nm was blue-shifted to 290 nm at the rutile phase with reduced absorbance. Under the electric field of capillary electrophoresis (CE), TiO₂ NPs in anatase migrated and detected as a broaden peak, whereas the rutile NPs did not. In addition, anatase showed the highest photocatalytic activity in an UV-irradiated dye degradation assay in the following order: aTiO₂ > arTiO₂ > rTiO₂. Overall, the phases of TiO₂ NPs showed characteristic physicochemical properties regarding size, surface chemical properties, UV absorbance, CE migration, and photocatalytic activity.

• 대한원격탐사학회지
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• 제34권6_2호
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• pp.1239-1249
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• 2018

광학 위성영상은 레이더 영상에 비해 시각적으로 친숙한 영상을 제공한다. 하지만해빙종류에 대한 구분은 분광학적으로 쉽지 않아 기존 기계학습에서 주로 사용하는 분광정보를 이용한 분류기법을 이용했을 경우 광학영상에서 해빙종류의 구분은 매우 어렵다. 본 연구에서는 분광정보 기반의 분류모델이 아닌 딥러닝 기반 분류기법인 semantic segmentation을 이용하여 계층적, 공간적 패턴을 학습하여 해빙종류 분류를 수행하였다. 또한 주기적으로 획득되는 광학위성자료에 비해 감독분류에서 매우 중요한 양질의 레이블 자료는 수집하는데 있어 높은 시간 및 노동 비용이 소모된다. 본 연구에서는 부족한 레이블 자료로 인해 어려운 다중영상에 대한 감독분류 문제를 준지도학습과 능동학습의 결합을 통해 해결을 시도 하였다. 이를 통해 레이블 되지 않은 새로운 영상자료로부터 추가적인 레이블을 스스로 학습하여 분류모델을 강화할 수 있었으며, 이는 향후 광학영상 기반의 운영 가능한 해빙종류 산출물 개발에도 적용될 수 있을 것으로 기대된다.