• Communications of the Korean Mathematical Society
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• v.11 no.3
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• pp.557-562
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• 1996

We find an equivalent condition of $M_n(R)[x, \delta]$ to be primitive and characterize a special subring P of $M_n(R)$. Also, we find an equivalent condition of $P[x, \delta]$ to be primitive.

• Communications for Statistical Applications and Methods
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• v.19 no.3
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• pp.395-403
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• 2012

Process adjustment, also called engineering process control(EPC), is applied to maintain process output close to a target value by manipulating controllable variables, but special causes may still make the process deviate from the target and result in significant costs. Thus, it is important to detect and mediate deviations as early as possible. We propose a one-step detection method, the moving search block(MSB), with which the time and type of a special cause can be identified in short periods. A modified control rule that can entertain the effects of the special cause is proposed. A numerical example is presented to evaluate the performance of the proposed scheme.

• Journal of the Korean Mathematical Society
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• v.38 no.3
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• pp.503-521
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• 2001

A change of Finsler metric L(x,y)longrightarrowL(x,y) is called a Randers change of L, if L(x,y) = L(x,y) +$\rho$(x,y), where $\rho$(x,y) = $\rho$(sub)i(x)y(sup)i is a 1-form on a smooth manifold M(sup)n. Let us consider the special Randers change of Finsler metric LlongrightarrowL = L + $\beta$ by $\beta$. On the basis of this special Randers change, the purpose of the present paper is devoted to studying the conditions for Finsler space F(sup)n which are transformed by a special Randers change of Finsler spaces F(sup)n with ($\alpha$,$\beta$)-metrics of Douglas type to be also of Douglas type, and vice versa.

• Journal of Korean Society for Quality Management
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• v.32 no.2
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• pp.201-211
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• 2004

Process adjustment is a complimentary tool to process monitoring in process control. Process adjustment directs on maintaining a process output close to a target value by manipulating another controllable variable, by which significant process improvement can be achieved. Therefore, this approach can be applied to the 'Improve' stage of Six Sigma strategy. Though the optimal control rule minimizes process variability in general, it may not properly function when special causes occur in underlying process, resulting in off-target bias and increased variability in the adjusted output process, possibly for long periods. In this paper, we consider a responsive feedback control system and the minimum mean square error control rule. The bias in the adjusted output process is investigated in a general framework, especially focussing on stationary underlying process and the special cause of level shift type. Illustrative examples are employed to illustrate the issues discussed.

• Honam Mathematical Journal
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• v.45 no.3
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• pp.491-502
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• 2023

As a generalization of Berwald spaces, we have the ideas of Douglas spaces and Landsberg spaces. S. Bacso defined a weakly-Berwald space as another generalization of Berwald spaces. In 1972, Matsumoto proposed the (α, β) metric, which is a Finsler metric derived from a Riemannian metric α and a differential 1-form β. In this paper, we investigated an important class of (α, β)-metrics of the form $F={\mu}_1\alpha+{\mu}_2\beta+{\mu}_3\frac{\beta^2}{\alpha}$, which is recognized as a special form of the first approximate Matsumoto metric on an n-dimensional manifold, and we obtain the criteria for such metrics to be weakly-Berwald metrics. A Finsler space with a special (α, β)-metric is a weakly Berwald space if and only if B^m_m is a 1-form. We have shown that under certain geometric and algebraic circumstances, it transforms into a weakly Berwald space.

• Proceedings of the PSK Conference
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• 2000.10a
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• pp.174.2-175
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• 2000

• Journal of the Korean Society for Library and Information Science
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• v.52 no.2
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• pp.5-25
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• 2018

This study is a broad examination researchon LIS students' perception about public library's subject special services and subject special librarian. Students majoring in Library and Information Science as respondents, it examined the recognition level of subject special services and subject special librarian, cognition level of necessity, competencies of subject special librarians and students and opinions on special status system of subject psecial librarians. Main factors shown in the results include the the level of students' understanding and necessity of subject special services and subject special librarian, students' willingness to work as a subject special librarian, the willingness to put additional effort into equip themselves with competencies as subject special librarians. There were respondents who have equipped competencies as subject special librarians through courses provided by the department of Library and Information Science and school curriculum but have not done anything further. Respondents responded that there is a need to systematize special status system of subject special librarian and that subject specialty is important in implementing subject special services but that there is a lack of subject specialty. Based on the research results, this study suggests that there is a need to put more emphasis on developing curriculum that can help overcoming difficulties faced by students majoring in Information Sciecne and help them become competent subject special librarians.

• Korean Journal of Medicinal Crop Science
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• v.19 no.3
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• pp.157-161
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• 2011

Growth characteristics, root yield and ginsenoside contents of 3-year-old ginseng in greenhouse shaded by $30^{\circ}$ sloped-curtain made of aluminum were compared to traditional shade facility in order to develop cultural practice for organic ginseng. Light transmittance ratio in greenhouse with $30^{\circ}$ sloped-curtain shade was distinctly lower than that of traditional shade from sunrise to 9 a.m., while its ratio in greenhouse was higher than traditional shade since 9 a.m. due to the reflection of light. Air temperature of greenhouse was $1.3^{\circ}C$ higher than that of traditional shade on the first ten days of August due to more reflected light. Root yield of greenhouse was 44% higher than that of traditional cultivation because of the inflow of reflected light and the decrease of disease of Alternaria and Anthracnose by blocking rainfall. Dry matter partitioning ratio of rhizome and lateral root were increased in ginseng cultivated at greenhouse due to longer survival time in leaf than traditional cultivation. Total ginsenoside contents cultivated at greenhouse was decreased in the part of taproot, while it was increased in the part of lateral and fine root compare to traditional cultivation. Individual ginsenoside contents between greenhouse and traditional cultivation showed significant difference more frequent in fine root than taproot and lateral root. Total ginsenoside contents including $Rb_1$, $Rb_2$, Rc, Rd, Re, Rf, $Rg_1$, and $Rg_2$ in whole root of 3-year-old ginseng did not showed significant difference by greenhouse and traditional cultivation.

• Journal of Ginseng Research
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• v.45 no.2
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• pp.325-333
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• 2021

Background: Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders. Enhancing hippocampal neurogenesis by promoting proliferation and differentiation of neural stem cells (NSCs) is a promising therapeutic strategy for AD. 20(S)-protopanaxadiol (PPD) and oleanolic acid (OA) are small, bioactive compounds found in ginseng that can promote NSC proliferation and neural differentiation in vitro. However, it is currently unknown whether PPD or OA can attenuate cognitive deficits by enhancing hippocampal neurogenesis in vivo in a transgenic APP/PS1 AD mouse model. Here, we administered PPD or OA to APP/PS1 mice and monitored the effects on cognition and hippocampal neurogenesis. Methods: We used the Morris water maze, Y maze, and open field tests to compare the cognitive capacities of treated and untreated APP/PS1 mice. We investigated hippocampal neurogenesis using Nissl staining and BrdU/NeuN double labeling. NSC proliferation was quantified by Sox2 labeling of the hippocampal dentate gyrus. We used western blotting to determine the effects of PPD and OA on Wnt/GSK3β/β-catenin pathway activation in the hippocampus. Results: Both PPD and OA significantly ameliorated the cognitive impairments observed in untreated APP/PS1 mice. Furthermore, PPD and OA significantly promoted hippocampal neurogenesis and NSC proliferation. At the mechanistic level, PPD and OA treatments resulted in Wnt/GSK-3β/β-catenin pathway activation in the hippocampus. Conclusion: PPD and OA ameliorate cognitive deficits in APP/PS1 mice by enhancing hippocampal neurogenesis, achieved by stimulating the Wnt/GSK-3β/β-catenin pathway. As such, PPD and OA are promising novel therapeutic agents for the treatment of AD and other neurodegenerative diseases.

• IMMUNE NETWORK
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• v.24 no.2
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• pp.12.1-12.17
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• 2024

Exosomes are double phospholipid membrane vesicles that are synthesized and secreted by a variety of cells, including T cells, B cells, dendritic cells, immune cells, are extracellular vesicles. Recent studies have revealed that exosomes can play a significant role in under both physiological and pathological conditions. They have been implicated in regulation of inflammatory responses, immune response, angiogenesis, tissue repair, and antioxidant activities, particularly in modulating immunity in autoimmune diseases (AIDs). Moreover, variations in the expression of exosome-related substances, such as miRNA and proteins, may not only offer valuable perspectives for the early warning, and prognostic assessment of various AIDs, but may also serve as novel markers for disease diagnosis. This article examines the impact of exosomes on the development of AIDs and explores their potential for therapeutic application.