• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.22 no.4
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• pp.302-306
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• 2011

Objectives : To investigate the cognitive functions of pediatric cancer patients and to test the hypotheses that the impairment of processing speed and working memory are more prevalent in children with medulloblastoma (MBL) compared to children with neuroblastoma (NBL). Methods : We gave the Korean version of the Wechsler Intelligent Scale for Children-III to 21 children with MBL and 24 children with NBL during outpatient follow-up after the treatment was completed. Results : Children with MBL showed below average performance across most of the sub-tests. The full scale IQ, verbal IQ, and performance IQ of children with MBL were significantly lower than those of children with NBL. There were significant differences between two groups in coding and Digit Span subtest scores. Children with MBL performed especially poorly in the coding subtest. Conclusion : These findings support previous reports of generally low IQ and the dysfunction of processing speed and working memory among children with MBL, a kind of central nervous system tumor. Further investigation is needed to determine how the deficit of processing speed and working memory affect neurocognitive development and general intelligent functions.

• Journal of Oriental Neuropsychiatry
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• v.20 no.2
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• pp.121-131
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• 2009

Objectives : From Scrophularia buergeriana water extract(SBW), has been used in vivo test for its beneficial effects on neuronal survival and neuroprotective functions, particularly in connection with APP-related dementias and Alzheimer's disease(AD). $A{\beta}$ oligomer derived from proteolytic processing of the ${\beta}$-amyloid precursor protein(APP), including the amyloid-${\beta}$ peptide($A{\beta}$), play a critical role in the pathogenesis of Alzheimer's dementia. Methods : Using drosophila APP model on APP-induced neuronal cytotoxicity, we demonstrated that SBW prevents neurotoxicity of $A{\beta}$ oligomer, which are the behavior, and possibly causative, feature of AD. We investigated the neuroprotective effects of SBW against the effects of oligomeric $A{\beta}$ and fly behaveior and life span by UAS-GRIM/APP-GAL within transgenic flies. Results and Conclusions : SBW repaired damage leading to the behaveior of APP-induced fly and delayed life span. These results suggest that neuronal damage in AD might be due to two factors: a direct $A{\beta}$ oligomer toxicity and multiple cellular and molecular neuroprotective mechanisms, including attenuation of apoptosis and direct inhibition of $A{\beta}$ oligomer, underlie the neuroprotective effects of SBW.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.8
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• pp.565-570
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• 2013

Previous researches on mining sequential patterns mainly focused on discovering patterns from the point-based event. Interval events with a time interval occur in the real world that have the start and end point. Existing interval pattern mining methods that discover relationships among interval events based on the Allen operators have some problems. These are that interval patterns having three or more interval events can be interpreted as several meanings. In this paper, we propose the I_TPrefixSpan algorithm, which is an efficient sequence pattern mining technique for removing ambiguity in the Interval Patterns Mining. The proposed algorithm generates event sequences that have no ambiguity. Therefore, the size of generated candidate set can be minimized by searching sequential pattern mining entries that exist only in the event sequence. The performance evaluation shows that the proposed method is more efficient than existing methods.

• Journal of the Korea Society of Computer and Information
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• v.27 no.12
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• pp.277-284
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• 2022

In this paper, we proposes a method of optimizing the processing order of skids to minimize the span time in a conveyor environment of the shipbuilding subassembly process. The subassembly process consists of a series of fixed tasks where the required work time is varied according to the skid type. The loading order of skids on a conveyor which determines the span time should be properly optimized and the problem size exponentially increases with the number of skids. In this regard, we propose a novel method called UniDev by defining a measure of the mean-absolute-deviation about the time difference among simultaneously processed tasks and iteratively improving it. Through simulations with various numbers of skids and processes, it was observed that our proposed method can efficiently reduce the overall work time compared with the multi-start and the 2-OPT methods.

• Korean Journal of Child Studies
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• v.30 no.6
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• pp.125-137
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• 2009

This study reviews facts and trends of harmful environments in the last decade that negatively affected children's development. Younger children have been exposed to harmful media, drugs, facilities, and objects. A matter of chemical substances contaminating in-door air has become quite controversial, recently. In order to provide a better understanding of harmful environments against children, there are great needs for a survey covering all ages based on the clear definition of the term harmful environments, research identifying its causal effects on child development in the context of both parent-child and peer relationships, and a longitudinal study processing its effects in a life-span perspective. It is suggested that by providing parent education and a plenty of cultural facilities as social efforts to create sound family culture, psycho-social and physical environments of children are improved. Furthermore, legal regulations and supervision on harmful environments are needed to be strengthened.

• The KIPS Transactions:PartC
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• v.8C no.1
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• pp.12-15
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• 2001

A summation generator creates sequence from addition with carry of LFSR (Linear Feedback Shift Register) sequences. Similarly, it is possible to generate keystream by bitwise exclusive-oring on two FCSR sequences. In this paper, we described the cryptographic properties of a sequence generated by the FCSRs.

• Proceedings of the Korea Concrete Institute Conference
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• 1994.10a
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• pp.368-373
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• 1994

Recently, a large number of box girder bridges with cantilevered decks have been constructed. Especially, segmentally erected prestressed concrete box girder bridges are widely used as economic and aesthetic solutions for long span bridges. Segmental erection is a particularly attractive construction alternative in cases where continuously supported formwork is impractical or uneconomical. In segmentally erected bridges, the structural systems are changed as the construction stages are progressive and redistribution of member forces occurs due to time dependent effects of concrete and relaxation of prestressing steel. Then, in segmentally erected bridges, analysis are required at each construction states. In this study, nonlinear analysis progam of the segmentally erected prestressed concrete box girder bridges is developed in taking into account nonlinearity of material and geometry, time dependent effect of concrete and relaxation of prestressing steel.

• Smart Structures and Systems
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• v.11 no.1
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• pp.123-134
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• 2013

Identifying structural modal parameters, especially those modes within high frequency range, from ambient data is still a challenging problem due to various kinds of uncertainty involved in vibration measurements. A procedure applying an ensemble empirical mode decomposition (EEMD) method is proposed for accurate and robust structural modal identification. In the proposed method, the EEMD process is first implemented to decompose the original ambient data to a set of intrinsic mode functions (IMFs), which are zero-mean time series with energy in narrow frequency bands. Subsequently, a Sub-PolyMAX method is performed in narrow frequency bands by using IMFs as primary data for structural modal identification. The merit of the proposed method is that it performs structural identification in narrow frequency bands (take IMFs as primary data), unlike the traditional method in the whole frequency space (take original measurements as primary data), thus it produces more accurate identification results. A numerical example and a multiple-span continuous steel bridge have been investigated to verify the effectiveness of the proposed method.

• Smart Structures and Systems
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• v.22 no.1
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• pp.95-103
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• 2018

Active vibration control via inertial mass actuators has been shown as an effective tool to significantly reduce human-induced vertical vibrations, allowing structures to satisfy vibration serviceability limits. However, a lot of practical obstacles have to be solved before experimental implementations. This has motivated simple control techniques, such as direct velocity feedback control (DVFC), which is implemented in practice by integrating the signal of an accelerometer with a band-pass filter working as a lossy integrator. This work provides practical guidelines for the tuning of DVFC considering the damping performance, inertial mass actuator limitations, such as stroke and force saturation, as well as the stability margins of the closed-loop system. Experimental results on a full scale steel-concrete composite structure (behaves similar to a footbridge) with adjustable span are reported to illustrate the main conclusions of this work.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.11a
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• pp.21-32
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• 2003

Developments and applications of the structural health monitoring (SHM) systems have become active particularity for long-span bridges in Korea. They are composed of sensors, data acquisition system, data transmission system, information processing, damage assessment, and information management. In this paper, current status of research and application activities on SHM systems for civil infra-structures in Korea are briefly introduced by 4 parts: (1) current status of bridge monitoring systems on existing and newly constructed bridges, (2) research and development activities on smart sensors such as optical fiber sensors and piezo-electric sensors, (3) structural damage detection methods using measured data, and (4) a test road project for pavement design verification and enhancement by the Korea Highway Corporation. Finally the R＆D activities of a new engineering research center entitled Smart Infra-Structure Technology Center at Korea Advanced Institute of Science and Technology are also briefly described.