• Title/Summary/Keyword: Spacer Design

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The Design and Synthesis of 1,4-Substituted Piperazine Derivatives as Triple Reuptake Inhibitors

  • Han, Min-Soo;Han, Young-Hue;Song, Chi-Man;Hahn, Hoh-Gyu
    • Bulletin of the Korean Chemical Society
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    • v.33 no.8
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    • pp.2597-2602
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    • 2012
  • Novel 1,4-substituted piperazine derivatives 5, Series A and B were designed by fragment analysis and molecular modification of 4 selected piperazine-containing compounds which possess antidepressant activity. We synthesized new 39 analogues of Series A and 10 compounds of Series B, respectively. The antidepressant screening against DA, NE, and serotonin neurotransmitter uptake inhibition was carried out using the Neurotransmitter Transporter Uptake Assay Kit. The compounds in Series B showed relatively higher reuptake inhibitory activity for SERT, NET, and DAT than those in Series A. The length of spacer between the central piperazine core and the terminal phenyl ring substituted at the piperazine ring in Series B seems to exert an important role in the activity.

Ku-Band Dielectric Resonator Bandpass Filter for Satellite Transponder (인공 위성 중계기용 Ku-Band 유전체 공진기 대역 통과 필터)

  • 김상철;이찬주;홍의석
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.29A no.11
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    • pp.49-56
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    • 1992
  • In this paper a band-pass filter using dielectric resonators with tuning screw and spacer at Ku-band is designed and constructed. For the filter design and construction, the coupling coefficient K between two resonators is numberically evaluated. The external quality factor Q$_{ex}$ is also calculated with a microstrip line which is necessary for the field excitation of dielectric resonator. The coupling between dielectric resonator and microstrip line depends mainly upon the magnetic field and is principal parameter in band-pass filter. The Q$_{ex}$ and K data which are evaluated by numberical analysis are practically applied to the filter construction. The theoretical Band-pass filter responses are given by Chebyshev approximation and they are nearly similar to the experimental results.

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Numerical Optimization of the Shape of Mixing Vane in Nuclear Fuel Assembly (핵연료 집합체 혼합날개형상의 수치최적설계)

  • Seo Jun-Woo;Kim Kwang-Yong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.8 s.227
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    • pp.929-936
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    • 2004
  • In the present work, shape of the mixing vane in Plus7 fuel assembly has been optimized numerically using three-dimensional Reynolds-averaged Navier-Stokes analysis of flow and heat transfer. Standard $k-{\epsilon}$ model is used as a turbulence closure. The Response surface method is employed as an optimization technique. The objective function is defined as a combination of heat transfer rate and inverse of friction loss. Bend angle and base length of mixing vane are selected as design variables. Thermal-hydraulic performances for different shapes of mixing vane have been discussed, and optimum shape has been obtained as a function of weighting factor in the objective function.

A Study on Functionally Graded Material Spacer and Electrodes Shape in Gas Insulated Switchgear for the Improvement of Insulation Performance (절연성능 향상을 위한 가스절연 개폐장치에서의 경사 기능성 재료 스페이서 및 전극 형상 연구)

  • Ju, Heung-Jin;Kim, Bong-Seok;Ko, Kwang-Cheol
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.1358_1359
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    • 2009
  • 가스 절연 개폐장치(Gas Insulated Switchgear : GIS)의 고체 스페이서에 경사기능성 재료(Functionally Graded Material : FGM)를 적용할 때, 전계의 완화를 예상할 수 있다. 특히, 균일 유전율 분포를 가지는 스페이서에서 양극 근처에 집중된 높은 전계가 FGM 스페이서를 사용할 때, 스페이서와 $SF_6$ 가스의 접촉부로 옮겨지며, 그 크기가 완화됨을 확인할 수 있었다[1]. 본 연구에서는 상용 고체 스페이서의 양극 부근에서의 전계 집중을 감소시키기 위해 전극 형상의 최적화를 수행하였다. 최적화 기법으로는 완전계승계획법(Full Factorial Design : FFD)과 결합된 반응표면법(Response Surface Method : RSM)을 이용하였으며, 균일 유전율 스페이서에서 양극 형상을 최적화하였다. 또한 타원형 유전율 분포를 가지는 FGM 스페이서를 이용함으로써, 상용 GIS 모델에 비해 최대 전계가 크게 완화될 수 있음을 확인하였으며, 상용 GIS의 외함부의 크기를 줄여 실제 소형화 가능 여부를 확인하였다.

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Design of Electrode and Insulator Contour Using Field Optimization (천계최적화에 의한 전극 및 절연체 형상설계)

  • Cho, Yun-Ok;Choi, Byoung-Joo;Kim, Kwang-Soo
    • Proceedings of the KIEE Conference
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    • 1989.07a
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    • pp.422-425
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    • 1989
  • This paper presents the algorithm of a new optimization method for axially symmetric electrode and insulator. The initial surface contour is divided into circular arc elements. The radii of the elements are determined so that the surface field distribution becomes uniform keeping the minimum gap distance and the direction of correction. By means of two examples, one for an electrode and the other for a spacer, the convergence behaviour and several restrictions of optimization are discussed.

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The Analysis of p-MOSFET Performance Degradation due to BF2 Dose Loss Phenomena

  • Lee, Jun-Ha;Lee, Hoong-Joo
    • Transactions on Electrical and Electronic Materials
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    • v.6 no.1
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    • pp.1-5
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    • 2005
  • Continued scaling of MOS devices requires the formation of the ultra shallow and very heavily doped junction. The simulation and experiment results show that the degradation of pMOS performance in logic and SRAM pMOS devices due to the excessive diffusion of the tail and a large amount of dose loss in the extension region. This problem comes from the high-temperature long-time deposition process for forming the spacer and the presence of fluorine which diffuses quickly to the $Si/SiO_{2}$ interface with boron pairing. We have studied the method to improve the pMOS performance that includes the low-energy boron implantation, spike annealing and device structure design using TCAD simulation.

A Study on Shield ring Design for Relieved Electric Field Intensity in GIS Spacer Triple Junction (GIS 스페이서 삼중점 전계 완화를 위한 쉴드링 설계에 관한 연구)

  • Kwon, Gumin;Lee, Seungkwan;Kang, Mincheol;Jeong, Kyengsik;Kim, Kyonghoe
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.1181-1182
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    • 2015
  • 본 논문에서는 초고압 가스절연개폐장치(GIS, Gas Insulated Switchgear) 내 고체 절연물인 스페이서에서 삼중점의 전계를 완화하기 위한 쉴드링 설계 방법과 그에 따른 효과를 분석하였다. 이를 위해 420kV GIS 스페이서를 축대칭 모델로 단순화하여 전계해석을 수행하였으며, 쉴드링 직경에 따른 삼중점 전계세기 변화를 확인하였다. 또한 쉴드링과 스페이서 계면 사이의 최소 이격거리를 계산하여 쉴드링의 최적 직경을 구하였다. 추가적으로, 새로운 설계 기법인 Double 쉴드링 기법을 소개하고 기존의 쉴드링이 하나인 경우와 비교 분석하여 그 효과를 확인하였다.

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A Study on Third Body Abrasion in the Small Clearance Region Adjacent to the Contact Area

  • Kim, Hyung-Kyu;Lee, Young-Ho;Heo, Sung-Pil;Jung, Youn-Ho
    • KSTLE International Journal
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    • v.4 no.1
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    • pp.8-13
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    • 2003
  • Abrasion in fretting wear mechanism is studied experimentally with the specimens of two different shapes of spacer grid spring and fuel tubes of a nuclear fuel. Reciprocating sliding wear test has been carried out in the environment of air and water at room temperature. Especially, third body abrasion is referred to for explaining the wear region expansion found during the slip displacement increase with constant normal contact farce. It is found that the expansion behaviour depends on the contact shape. The small clearance between the tube and spring seems to be the preferable region of the wear particle accumulation, which causes third body abrasion of the non-contact area. Even in water environment the third body abrasion occurs apparently. Since the abrasion on the clearance contributes wear volume, the influence of the contact shape on the severity of third body abrasion should be considered to improve the grid spring design in the point of restraining wear damage of a nuclear fuel.

Wide Viewing Angle Flexible Color Liquid Crystal Display

  • Liu, Kang-Hung;Lin, Yan-Rung;Chang, Ku-Hsien;Liao, Chi-Chang
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07a
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    • pp.357-360
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    • 2005
  • A novel wide viewing angle flexible liquid crystal display will be demonstrated. The crossed matrix-type micro-cell structure was adopted in this design. The LC domains were divided into four different tilted directions by the combination effect of pixel fringe field and crossed matrix type micro-cell. It can create four domains without rubbing process and form the cell gap without spacer. For flexible color fabrication, a novel inkjet printing technology is adopted. This cost effective wide viewing angle color flexible LCD technology can be a good solution for high performance flexible LCD.

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Analysis of unequal electric field by metal particle in GiS (GIS 내부의 도체이물질에 의한 불평등 전계 해석)

  • Park, Kyoung-Su;Kim, Jin;Lee, Hee-Bock;Ko, Young-Ho
    • Proceedings of the KIEE Conference
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    • 2000.11c
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    • pp.531-533
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    • 2000
  • In compared with air insulated switchgear, GIS has a high efficiency and confidence So the transformer substation can be reduced the size to 1/10. Insulation method using $SF_6$ gas has a very excellent insulation characteristics for high pressure equipment but has a characteristics that insulation heredity is changed for internal unequal electric field. So analysis of electromagnetic field in GIS is very important basic data for structure design and trouble diagnosis process. In compared with established method, SNM in this paper observes variation of the electromagnetic field with real time and get result very similar to measurement. In order to know the variation of electromagnetic field distribution for transient response for time and position, variations are observed when the spacer is bonded and metal particles are moving fast.

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