• Title/Summary/Keyword: Sp10

Search Result 6,194, Processing Time 0.042 seconds

A Comparative Study on Information Security Management Activity of Public Sector in USA & Korea (미국과 우리나라의 정보보안관리 활동 비교연구)

  • Kim So-Jeong
    • The KIPS Transactions:PartC
    • /
    • v.13C no.1 s.104
    • /
    • pp.69-74
    • /
    • 2006
  • USA is strengthening the information sanity by managing federal agency's information and information system systematically. For this purpose, US government put the Federal Information Security Management Act into the E-Government Act of 2002. According to the FISMA, it is required to have information security management plan for ail federal agencies. In addition that, Inspector Generals of these agencies should assess the status of their agency and report the result to the office of Management and Budget. Collecting all the reports from each agency, OMB should report to GAO on general status of information security of federal agency. It is helpful to provoke the information security as a necessary activity to realize the E-government. Comparing these efforts with our system will give us good implications to get more idea to secure our information system.

Transcriptional activation of human GM3 synthase (hST3Gal V) gene by valproic acid in ARPE-19 human retinal pigment epithelial cells

  • Song, Na-Ree;Kim, Seok-Jo;Kwon, Haw-Young;Son, Sung-Wook;Kim, Kyoung-Sook;Ahn, Hee-Bae;Lee, Young-Choon
    • BMB Reports
    • /
    • v.44 no.6
    • /
    • pp.405-409
    • /
    • 2011
  • The present study demonstrated that valproic acid (VPA) transcriptionally regulates human GM3 synthase (hST3Gal V), which catalyzes ganglioside GM3 biosynthesis in ARPE-19 human retinal pigment epithelial cells. For this, we characterized the promoter region of the hST3Gal V gene. Functional analysis of the 5'-flanking region of the hST3Gal V gene revealed that the -177 to -83 region functions as the VPA-inducible promoter and that the CREB/ATF binding site at -143 is crucial for VPA-induced expression of hST3Gal V in ARPE-19 cells. In addition, the transcriptional activity of hST3Gal V induced by VPA in ARPE-19 cells was inhibited by SP600125, a c-Jun N-terminal kinase (JNK) inhibitor. In summary, our results identified the core promoter region in the hST3Gal V promoter and for the first time demonstrated that ATF2 binding to the CREB/ATF binding site at -143 is essential for transcriptional activation of hST3Gal V in VPA-induced ARPE-19 cells.

Effect of Laser Shock Peening Simulation Parameters on Residual Stress of Inconel Alloy 600 Steel (LSP 시뮬레이션 변수가 Inconel 600 합금의 잔류응력에 미치는 영향)

  • Kim, Ju-Hee;Kim, Yun-Jae;Kim, Joung-Soo
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.36 no.1
    • /
    • pp.43-50
    • /
    • 2012
  • The effects of parameters related to the finite element simulation of the laser shock peening(LSP) process on the residual stresses of Inconel alloy 600 steel are discussed. In particular, we focus on the maximum pressure, pressure pulse duration, laser spot size, and number of shots. It is found that certain ranges of the maximum pressure and pulse duration can produce the maximum compressive residual stresses near the surface, and thus proper choices of these parameters are important. The residual stresses are not affected by the laser spot size, provided it is larger than a certain size. The magnitudes of the compressive residual stresses and the plastically affected depths are found to increase with an increasing number of shots, but this effect is less pronounced for more shots.

Market Trend of Health Functional Food and the Prospect of Ginseng Market (건강기능식품의 시장현황 및 인삼시장의 전망)

  • Lee, Jong-Won;Do, Jae-Ho
    • Journal of Ginseng Research
    • /
    • v.29 no.4
    • /
    • pp.206-214
    • /
    • 2005
  • The health function food law has been carried into effect from January 31, 2004 just after the proposal of 'a draft of a proposed law concerning the health function foods for the promotion of a nation health' on November 29, 2000 in Korea. After enforcement of health functional food law, there have been difficult market penetration with overall stagnancy of business activities and the current of health functional food within the country divided two groups. In standardized health functional foods the present condition, nutrition supplementary products (938 items) and red ginseng products (351 items) are prevalent and total 32 products are registered containing lactobacilli (297 items), glucosamine (295 items), ginseng (182 items), yeast(136 items) so on. In 2005, five products (products containing green tea extract, soybean protein, plant sterol, fructooligo sugar and Monascus sp. products are newly notified and raw material or component of total 21 products containing xylitol, teanin extract, sardine peptide are recognized as individual authorized health functional foods. Efficacies of ginseng are studied in many-sided researches but benefits of the ginseng in the health functional food law limited to 3 items (staminaresume, immune enhancement, nourishment robustness). To enlarge functionalities of ginseng it needs raw material and ingredient approval through data application to Korea Food and Drug Administration and this procedure acts as barrier of the functional food development in the ginseng industry. It is necessary to develop the authorized health functional foods for leading health functional food market in the future.

Runtime Prediction Based on Workload-Aware Clustering (병렬 프로그램 로그 군집화 기반 작업 실행 시간 예측모형 연구)

  • Kim, Eunhye;Park, Ju-Won
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.38 no.3
    • /
    • pp.56-63
    • /
    • 2015
  • Several fields of science have demanded large-scale workflow support, which requires thousands of CPU cores or more. In order to support such large-scale scientific workflows, high capacity parallel systems such as supercomputers are widely used. In order to increase the utilization of these systems, most schedulers use backfilling policy: Small jobs are moved ahead to fill in holes in the schedule when large jobs do not delay. Since an estimate of the runtime is necessary for backfilling, most parallel systems use user's estimated runtime. However, it is found to be extremely inaccurate because users overestimate their jobs. Therefore, in this paper, we propose a novel system for the runtime prediction based on workload-aware clustering with the goal of improving prediction performance. The proposed method for runtime prediction of parallel applications consists of three main phases. First, a feature selection based on factor analysis is performed to identify important input features. Then, it performs a clustering analysis of history data based on self-organizing map which is followed by hierarchical clustering for finding the clustering boundaries from the weight vectors. Finally, prediction models are constructed using support vector regression with the clustered workload data. Multiple prediction models for each clustered data pattern can reduce the error rate compared with a single model for the whole data pattern. In the experiments, we use workload logs on parallel systems (i.e., iPSC, LANL-CM5, SDSC-Par95, SDSC-Par96, and CTC-SP2) to evaluate the effectiveness of our approach. Comparing with other techniques, experimental results show that the proposed method improves the accuracy up to 69.08%.

Electronic Structures and Magnetism at the Interfaces of Rocksalt Structured Half-metallic NaN and CaN (암염구조를 가지는 반쪽금속 CaN과 NaN의 계면 전자구조에 관한 연구)

  • Kim, Dong-Chul;Bialek, Beata;Lee, Jae-Il
    • Journal of the Korean Magnetics Society
    • /
    • v.22 no.5
    • /
    • pp.157-161
    • /
    • 2012
  • Magnetism at the interfaces of rocksalt structured half-metals, NaN and CaN were investigated by use of the first-principles band calculations. The electronic structures for the simple interface and mixed interface systems were calculated by the FLAPW (full-potential linearized augmented plane wave) method. From the calculated number of electrons in muffin-tin spheres of each atom, we found, for the simple interface system, that the magnetic moment of the N atom in the CaN (NaN) side is increased (decreased) compared to those of inner N atoms. For the mixed interface system, the magnetic moments of the interface N atoms are similar to the averaged value for the inner N atoms in CaN and NaN side. Among four interface N atoms, the N atom connected to Na atoms in the upper and down layers has the largest magnetic moment and that connected to Ca atoms has the smallest. The number of p electrons in each N atom and the calculated density of states explain well the above situation.

Development of Mode Choice Model and Applications Considering Connectivity of Express Way (고속도로 연계성을 반영한 고속철도 수단선택모형 개발 및 적용)

  • Cho, Hang-Ung;Chung, Sung-Bong;Kim, Si-Gon;Oh, Jae-Hak
    • Journal of the Korean Society for Railway
    • /
    • v.14 no.4
    • /
    • pp.383-389
    • /
    • 2011
  • Until now, in planning and constructing KTX and the Express Way, the connectivity and transfer between these facilities have not been considered. In this study the effect of mode choice behavior by connecting KTX and the Express Way is analyzed through estimating Multinomial Logit Model and Binary Logit Model. The SP and RP surveys to develop these models were carried out and the data were selected from the passengers using the KTX station, Express Bus Terminals and Rest Areas in the Express Way. To test the effect of connectivity and transfer in the field, the case study for Dongtan KTX station was carried out. According to the results, connecting the KTX station and the Express Way has the effect of increasing the demand by 30%. And this is caused by saving about 120 minutes of traveling time from Seoul to Pusan. This study shows that the connectivity and transfer can increase the efficiency of transportation system and the improvement in the mobility and accessibility will maximize the usages of these two facilities.

Analysis on Acceptance and Use of Technology for Elementary School Teachers in Telepresence Robot-assisted Learning (원격 로봇보조학습에 대한 초등교사의 기술수용도 분석)

  • Lee, Hyewon;Han, JeongHye
    • Journal of The Korean Association of Information Education
    • /
    • v.23 no.6
    • /
    • pp.599-606
    • /
    • 2019
  • Telepresence robot-assisted learning can provide opportunities of education for students who are in vulnerable physical, intellectual, cultural or environmental conditions. It is to be applied in international virtual education for global citizenship education. To date, the study of acceptance model has been conducted only for preservice teachers, and post-intention for use is not considered. This paper identified whether there are significant differences by gender or years of experience from elementary school teachers on it and the basic factors that affect the acceptance intentions for it. Factors related to intention to use for a telepresence robot were investigated, and a questionnaire about post-intention for use was made after participants operated. The results showed that elementary school teachers did not have a significant difference in each factor by gender. The experienced teachers showed no difficulty in using it. It was shown that PU, ATT, PENJ, SI and Ttrust were all extremely significant factors to affect acceptance intentions. It will be possible to establish educational information policies based on the acceptance intentions of elementary school teachers on telepresence robot-assisted learning.

Clinical Study of Oriental Medical Treatment 1 Case of Patient with Oral Dyskinesia (토농설(吐弄舌) 환자(患者) 1례(例)에 대한 임상적(臨床的) 고찰(考察))

  • Hwang, Kyu-Jeong;Yang, Gi-Young;Jang, Suk-Gun;Kim, Young-Hwa;Hong, Kwon-Eui;Lee, Hyun;Lee, Byung-Ryul
    • Journal of Acupuncture Research
    • /
    • v.19 no.1
    • /
    • pp.262-269
    • /
    • 2002
  • By process of trearment for case diagnosed as Oral Dyskinesia and admitted from the 3lth, July, 2001 to the 1st, September, 2001, the results are as follows. Method and Results : This patient was diagnosed as Oral Dyskinesia of Shaoyang disease with interior syndrome that was based by disorder of hepatic qi, medicated shihogayonggolmoreutang(shihujiayonggumolie-tang), gamisoyo-san(jiaweishaoyao-san) and acupun - cturetherapy was taken on proximal and disital acupoints including Yingu(B10, 陰谷), Zulingyi(G41, 足臨泣), Jianshi(P5, 間使), Shenmen(H6, 神門), Sanyinjiao(Sp6, 三陰交), Yi - ntang(Extra point, 印堂), Lianquan(CV23, 康泉), Qihai(CV6, 氣海) and Danhange(Damhangyuk, 膽寒格), Ganjeongge(ganjeonggyuk, 肝正格), Pizhengge(Bijeonggyuk, 脾正格) of Shayen - zhenfa(Shayamchimbeop, 舍岩鍼法). Conclusion : I consider that psychosomatic tremer disease including Oral Dyskinesia can improved by Oriental medical treatment and continuous research must be accumulated subsequently.

  • PDF

The Effect of Acupuncture in Promoting Neurogenesis and Angiogenesis after Middle Cerebral Artery Occlusion in Rats

  • Lee, Hong Min;Nam, Sang Soo;Kim, Yong Suk
    • Journal of Acupuncture Research
    • /
    • v.30 no.3
    • /
    • pp.1-13
    • /
    • 2013
  • Objectives : This study was performed to choose more effective neuro-protective acupuncture point and to verify the effect of acupuncture in promoting neurogenesis and angiogenesis as a result of its neuro-vasculo-regenerative effect in middle cerebral artery occlusion model in rats. Methods : By TTc staining we chose the most effective acupuncture point with neuro-protection. We randomly divided into four groups: Such as (1) sham group(with sham-operation), (2) sham+acupuncture group(with sham-operation), (3) middle cerebral artery occlusion group, (4) MCAO+AT group. Acupuncture procedure was performed for four days. Total RNA was extracted using TRIzol reagent, according to the manufacturer's instructions, and was purified using an RNAeasy mini kit. Immuno-histochemistry was performed using primary antibody mouse anti-BrdU, NeuN, Dcx, and VEGF. Results : We found that $ST_{36}$ had the more neuroprotective effect than $LI_{11}$ and $SP_3$. The microarray analysis revealed that 54 genes were more expressed neurogenesis pathway in MCAO+AT group compared with MCAO group(fold changes greater than or equal to twofold change). 11 genes were more expressed angiogenesis pathway. And 7 genes were more expressed VEGF pathway. Immuno-histochemistry revealed that cell proliferation, cell migration and cell maturation were increased. Conclusions : This study demonstrated that acupuncture on $ST_{36}$ had neuro-protective and neuro-restorative effect in ischemic brain injuries. And its mechanism might be related to promote neurogenesis and angiogenesis. These results suggest that acupuncture have potential benefits for the treatment of ischemic stroke.