Transcriptional activation of human GM3 synthase (hST3Gal V) gene by valproic acid in ARPE-19 human retinal pigment epithelial cells
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Song, Na-Ree
(Department of Biotechnology and Brain Korea 21 Center for Silver-Bio Industrialization, Dong-A University)
Kim, Seok-Jo (Department of Biotechnology and Brain Korea 21 Center for Silver-Bio Industrialization, Dong-A University) Kwon, Haw-Young (Department of Biotechnology and Brain Korea 21 Center for Silver-Bio Industrialization, Dong-A University) Son, Sung-Wook (Department of Biotechnology and Brain Korea 21 Center for Silver-Bio Industrialization, Dong-A University) Kim, Kyoung-Sook (Department of Biotechnology and Brain Korea 21 Center for Silver-Bio Industrialization, Dong-A University) Ahn, Hee-Bae (Department of Ophthalmology, College of Medicine, Dong-A University) Lee, Young-Choon (Department of Biotechnology and Brain Korea 21 Center for Silver-Bio Industrialization, Dong-A University) |
1 | Cinatl Jr., J., Cinatl, J., Driever, P. H., Kotchetkov, R., Pouckova, P., Kornhuber, B. and Schwabe, D. (1997) Sodium valproate inhibits in vivo growth of human neuroblastoma cells. Anticancer Drugs 8, 958-963. DOI |
2 | Choi, H. J., Chung, T. W., Kang, N. Y., Kim, K. S., Lee, Y. C. and Kim, C. H. (2003) Transcriptional regulation of the human GM3 synthase (hST3Gal V) gene during monocytic differentiation of HL-60 cells. FEBS Lett. 555, 204-208. DOI ScienceOn |
3 | Chung, T. W., Choi, H. J., Lee, Y. C. and Kim, C. H. (2005) Molecular mechanism for transcriptional activation of ganglioside GM3 synthase and its function in differentiation of HL-60 cells. Glycobiology 15, 233-244. |
4 | Kim, S. W., Lee, S. H., Kim, K. S., Kim, C. H., Choo, Y. K. and Lee, Y. C. (2002) Isolation and characterization of the promoter region of the human GM3 synthase gene. Biochim. Biophys. Acta. 1578, 84-89. DOI ScienceOn |
5 | Gupta, S., Campbell, D., Derijard, B. and Davis, R. J. (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267, 389-393. DOI ScienceOn |
6 | Bhoumik, A. and Ronai, Z. (2008) ATF2: a transcription factor that elicits oncogenic or tumor suppressor activities. Cell Cycle 7, 2341-2345. DOI |
7 | Morton, S., Davis, R. J. and Cohen, P. (2004) Signaling pathways involved in multisite phosphorylation of the transcription factor ATF-2. FEBS Lett. 572, 177-183. DOI ScienceOn |
8 | Rogawski, M. A. and Loscher, W. (2004) The neurobiology of antiepileptic drugs. Nat. Rev. Neurosci. 5, 553-564. DOI ScienceOn |
9 | Blaheta, R. A., Michaelis, M., Driever, P. H. and Cinatl Jr., J. (2005) Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies. Med. Res. Rev. 25, 383-397. DOI ScienceOn |
10 | Blaheta, R. A. and Cinatl Jr., J. (2002) Anti-tumor mechanisms of valproate: a novel role for an old drug. Med. Res. Rev. 22, 492-511. DOI ScienceOn |
11 | Hakomori, S. (2003) Structure, organization, and function of glycosphingolipids in membrane. Curr. Opin. Hematol. 10, 16-24. DOI ScienceOn |
12 | Bektas, M. and Spiegel, S. (2004) Glycosphingolipids and cell death. Glycoconjugate J. 20, 39-47. |
13 | Kwon, H. Y., Kang, N. Y., Dae, H. M., Kim, K. S., Kim, C. H., Do, S. I. and Lee, Y. C. (2008) Valproic acid-mediated transcriptional regulation of human GM3 synthase (hST3Gal V) in SK-N-BE(2)-C human neuroblastoma cells. Acta. Pharmacol. Sin. 29, 999-1005. DOI ScienceOn |
14 | Cinatl Jr., J., Cinatl, J., Scholz, M., Driever, P. H., Henrich, D., Kabickova, H., Vogel, J. U., Doerr, H. W. and Kornhuber, B. (1996) Antitumor activity of sodium valproate in cultures of human neuroblastoma cells. Anticancer Drugs 7, 766-773. DOI |
15 | Kwon, H. Y., Dae, H. M., Song, N. R., Kim, K. S., Kim, C. H. and Lee, Y. C. (2009) Valproic acid induces transcriptional activation of human GD3 synthase (hST8Sia I) gene in SK-N-BE(2)-C human neuroblastoma cells. Mol. Cells 27, 113-118. DOI ScienceOn |
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