• Journal of Applied Biological Chemistry
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• v.66
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• pp.244-249
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• 2023

Artemisia keiskeana and A. stolonifera are plants of the genus Artemisia, distributed in various regions, especially China and Korea. They are renowned as medicinal plants with biological and pharmacological activities. Fraxidin, isofraxidin, and daphnoretin are coumarins present in Artemisia spp.; however, research on them is limited. Therefore, this study was carried out to quantify the content of these compounds in the aerial parts of A. keiskeana and A. stolonifera in different regions in Korea. High-performance liquid chromatography was performed with a photodiode array detector and a reverse-phase INNO column. A. stolonifera only contained fraxidin with the highest amount found in Yongmun commune. A. keiskeana cultivation in Soyang commune gave the highest fraxidin and daphnoretin content. However, isofraxidin was not present in all samples. The findings suggest that the concentrations of the three compounds may differ depending on the growth site and provide a foundation for future studies.

• Journal of Korean Medical classics
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• v.10
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• pp.450-493
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• 1997

Three-yum and three-yang(三陰三陽) is the change state of yum-yang(陰陽) which is caused by six gi(六氣). They mean the flow of six gi(六氣) which exist throughout the viscera, the channel(經絡), and the skin. But it is not easy to understand the meaning because the contents of the attribute of three-yum and three-yang(三陰三陽), the bolt-leaf-hanges(關闔樞) theory and large or small of gi-blood(氣血多少) which is the main clue that explain it in ${\ll}$Somun(素問)${\gg}$ and ${\ll}$Yeongchu(靈樞)${\gg}$ don't coincide with each other. I, the writer, tried to understand the uncertain meaning and the contents which are written about three points above differently in each of the books that are ${\ll}$Somun(素問)${\gg}$ and ${\ll}$Yeongchu(靈樞)${\gg}$. So, from that the course that the book, ${\ll}$Huangjenegeong(黃帝內經)${\gg}$ is handed down is so relatively simple in a wood block-printed book, that the ${\ll}$Huangjenegeongtaeso(黃帝內經太素)${\gg}$ has less wong-words than the Somun(素問) and the Yeongchu(靈樞), and from that Yangshangsun(楊上善) wrote the note in the ${\ll}$Huangjenegeongtaeso(黃帝內經太素)${\gg}$ by royal order about 100 years former than Wangbing(王氷), as making projects of Yangshangsun(楊上善)'s note and the original of the ${\ll}$Huangjenegeongtaeso(黃帝內經太素)${\gg}$ which has relation to the yum-yang(陰陽) attribute of three-yum and three-yang(三陰三陽), the bolt-leaf-hanges(關闔樞) theory, and the large or small of gi-blood(氣血多少) and researching the Yangshangsun(楊上善)'s theory. The result is summarized like this. First, wherease the order of the change of three-yum and three-yang(三陰三陽) which is explained by Yangshangsun(楊上善) consider the change of yangi(陽氣) in body most important, the order of the change gaeggi(客氣)'s three-yum and three-yang(三陰三陽) considers chungi(天氣) most important, and the order of jugi(主氣)'s three-yum and three-yang(三陰三陽) considers jigi(地氣)'s change of ohaeng(五行) most important. If the order of change three-yum and three-yang(三陰三陽) in the ${\ll}$Huangjenegeongtaeso(黃帝內經太素)${\gg}$ is considered, each of taeyang(太陽) and soyum(少陰) are expressed as the base of yum-yang(陰陽) and yangmeong(陽明) and taeyum(太陰) are expressed as the palmy days of yum-yang(陰陽), soyang(少陽) and gyolyum(厥陰) are expressed as pacemaker(樞杻) which controls the change of yum-yang(陰陽). Thus, each has something in common that is fettered by the inside and outside. In the flow of channel(經絡), taeyang(太陽) and soyum(少陰) take charge of the behind of body, yangmeong(陽明) and taeyum(太陰) take charge of the front of body and soyang(少陽) and gyolyum(厥陰) take of the side of body. Second, in Yangshangsun(楊上善)'s bolt-leaf-hanges(關闔樞) theory, three-yum(三陰) is regarded as inside, three-yang(三陽) as outside, so when bolt, leaf and hanges fulfil their duties in inside and outside, the life(life force) is thought to be revealed normally. It is impossible to understand the bolt-leaf-hanges with the conception of the inside and outside which divide three-yum and three-yang(三陰三陽) into taeyang-soyum(太陽-少陰), yangmeong-taeyum(陽明-太陰), soyang-gyolyum(少陽-厥陰) according to yum-yang(陰陽) attribute, hence it need the special conception that is taeyang(太陽)-taeyum(太陰), yangmeong(陽明)-gyolyum(厥陰), soyang(少陽)-soyum(少陰) which center on their duties in inside and outside. In the denunciation of the word open(開) and bolt(關), because Yangshangsun(楊上善) said that the duities of taeyang(太陽) and taeyum(太陰) are shutter(閉禁), bolt(關) is coincided with that significance. Third, with explaining the large or small of gi-blood(氣血多少) of three-yum and three-yang(三陰三陽), Yangshangsun(楊上善) expressed the inside and outside either in the same way or differently. Because the inside and outside is interior of body and exterior of body, it is the explanation that is noticed by the fact that the property of large or small of gi-blood(氣血多少) is either able to be same or different. In this viewpoint, if we unite the contents about large or small of gi-blood(氣血多少) of ${\ll}$Somun(素問)${\gg}$, ${\ll}$Yeongchu(靈樞)${\gg}$, we will find that the descriptions of large or small of gi-blood(氣血多少) of three-yang(三陽) in ${\ll}$Somun(素問)${\gg}$ ${\ll}$Yeongchu(靈樞)${\gg}$ correspond with the ${\ll}$Huangjenegeongtaeso(黃帝內經太素)${\gg}$, but in three-yum(三陰), the contrary presentations exit. The reason is that large or small of gi-blood(氣血多少) of three-yum(三陰) isn't only expressed as che(體) in the point of che-yong(體用), but as a point of yong(用) that is a phenomenon. As researching the original of ${\ll}$Huangjenegeongtaeso(黃帝內經太素)${\gg}$ and Yangshangsun(楊上善)'s notes as a center about three problems that are yum-yang(陰陽) attribute, the bolt-leaf-hanges(關闔樞) and large or small of gi-blood(氣血多少) of three-yum and three-yang(三陰三陽), I, the writer, tried to explain the part which is written differently or has uncertain conception in the book ${\ll}$Somun(素問)${\gg}$ and the book ${\ll}$Yeongchu(靈樞)${\gg}$, but the concrete result of the work like this will be judged according to the question how many theories are correspondent with real presence at a sickbed. Hence, the work to veryfy the theories in the future will be left as assignment.

• Journal of Sasang Constitutional Medicine
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• v.8 no.1
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• pp.247-294
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• 1996

By means of the statistical data which has been collected with newly revised QSCC made use of the outpatient group examined at Kyung-Hee Medical Center and an open ordinary person group, the author proceeded statistical analysis for the validation study of the revised questionnaire itself. First, check the accurate discrimination rate by performing discriminant analysis on the statistical data of the patient group. And next, sought T-score by applying the norms gained in process of standadization of the open ordinary person group to the Sasang scale score of the outpatient group and investigated the distinctive feature between the subpopulations which was devided in the process of multivarite cluster analysis. The result was summarized as follows ; 1. The validity of the questionnaire was established through the fact that the accurate discrimination rate the ratio between predicted group and actual group was figured out 70.08%. 2. At the profile analysis the response to the relevant scale showed notable upward tendency in each constitutional group and therefore it seems to be pertinent in the field of constitutional discrimination. 3. In the observation of the power of expression through the profile analysis of each constitutional group the Soyang group demonstrated the most remarkable outcome, the Soeum group was the most inferior and the Taieum group revealed a sort of dual property. 4. What is called the group of seceder out of three subpopulation of each constitutional group distinguished definitely from the contrasted groups at the point of the distinctive profile feature and the content is like following description. (1) The seceder group of Soyang-in showed considerably passive disposition differently from general character of ordinary Soyang group and an appearance attracting the attention is that they demonstrated comparatively higher response at Soeum scale (2) The seceder group of Taieum-in gained low scores in general that informed the passive disposition of the group and the other way of the general property of Taieum group which showed accompanied ascension in Taiyang-Taieum scales they demonstrated sharply declined score at Taiyang scale (3) The seceder group of Soeum-in demonstrated distinctive property similar to the profile feature of Soyang group and it notifies that the passive property of Soeum group was diluted for the most part. According to the above result, the validity of newly revised questionnaire has been proven successfully and the property of seceder groups could be noticed to some degree through the profile analysis on the course of this study. The result of this study is expected to use as a research materials to produce next edition of the questionnaire and it is regarded that further inquisition about the difference between the seceder group and the contrasted group is required for the promotion of the questionnaire as it refered several times in the contents of the main discourse.

• Journal of Korean Medicine for Obesity Research
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• v.14 no.2
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• pp.63-71
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• 2014

Objectives: This study was designed to investigate the correlation between Sasang constitution and dyslipidemia and the possibility that Sasang constitution can be a risk factor of dyslipidemia. Methods: This study was a retrospective cross-sectional study based on chart review. Seventeen thousand sixty-nine charts which were collected from May 2007 to June 2010 in International Healthcare Service Center, Kyung Hee University Medical Center, were reviewed for the study. Fifteen thousand two hundred fifty charts including Sasang constitutional diagnosis and lipid profiling were selected and we examined the correlation between Sasang constitution and dyslipidemia. Results: After adjusted for body mass index, the levels of total cholesterol and triglyceride were highest in Taeeum group, and lowest in Soeum group. High-density lipoprotein was highest in Soeum group, and lowest in Taeeum group. After adjusted for age, sex, and body mass index, the odds ratios for 'high triglyceride' were 1.716 (1.411~2.087) in Soyang group and 2.021 (1.650~2.475) in Taeeum group compared to Soeum group. The odds ratio for 'high low-density lipoprotein' was 1.229 (1.006~1.501) in Soyang group compared to Soeum group. The odds ratios for 'low high-density lipoprotein' were 1.195 (1.033~1.381) in Soyang group and 1.414 (1.212~1.649) in Taeeum group compared to Soeum group. Conclusions: The lipid profiles and dyslipidemic risk differed across constitutional types, showing constitution type-specific patterns, so that we could infer the possibility that Sasang constitutional types can be a risk factor of dyslipidemia.

• Korean Journal of Ecology and Environment
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• v.40 no.2
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• pp.201-213
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• 2007

In this study, the Batter Assessment Science Integrating point and Nonpoint Sources (BASINS 3.0)/window interface to Hydrological Simulation Program-FPRTRAN (WinHSPF) was applied for assessment of Soyang Dam watershed. WinHSPF calibration was performed using monitoring data from 2000 to 2004 to simulate stream flow. Water quality (water temperature, DO, BOD, nitrate, total organic nitrogen, total nitrogen, total organic phosphorus and total phosphorus) was calibrated. Calibration results for dry-days and wet-days simulation were reasonably matched with observed data in stream flow, temperature, DO, BOD and nutrient simulation. Some deviation in the model results were caused by the lack of measured watershed data, hydraulic structure data and meteorological data. It was found that most of pollutant loading was contributed by nonpoint source pollution showing about $98.6%{\sim}99.0%$. The WinHSPF BMPRAC was applied to evaluate the water quality improvement. These scenarios included constructed wetland for controlling nonpoint source poilution and wet detention pond. The results illustrated that reasonably reduced pollutant loadin. Overall, BASINS/WinHSPF was found to be applicable and can be a powerful tool in pollutant loading and BMP efficiency estimation from the watershed.

• Korean Journal of Environment and Ecology
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• v.28 no.5
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• pp.559-565
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• 2014

The fish and attached fish eggs by artificial floating island in lake Soyang was investigation from May to June 2013. The observed fish at the floating island during the survey period were Zacco platypus (5.2 %), Siniperca scherzeri (1.0 %), Lepomis macrochirus (90.8 %) and Micropterus salmoides (3.0 %) at the Cheongpyeong-ri, Cyprinus carpio (0.4 %), Z. platypus (54.6 %), L. macrochirus (20.3 %) and M. salmoides (24.7 %) at the Ungjin-ri. The collected species at the neighboring facility were 22 species belonging the seven families. Among them, exotic species such as Carassius cuvieri, L. macrochirus and M. salmoides. Also, Z. platypus (30.4 %), L. macrochirus (18.9 %), Opsariichthys uncirostris amurensis (15.4 %) and Hemibarbus labeo (9.3 %) were numberous. Attached fish eggs number were 708,800 (800 per $m^2$) at the Cheongpyeong-ri and 974,500 (1,100 per $m^2$) at the Ungjin-ri. The fish eggs number were 504,920 of the Carassius auratus (212,640 at the Cheongpyeong-ri, 292,280 at the Ungjin-ri) and 1,178,380 of the C. carpio (496,160 at the Cheongpyeong-ri, 682,220 at the Ungjin-ri). The hatched eggs number were 350,505 of the C. auratus(102,067 at the Cheongpyeong-ri, 248,438 at the Ungjin-ri) and 811,222 of the C. carpio (238,157 at the Cheongpyeong-ri, 573,065 at the Ungjin-ri).

• Journal of Sasang Constitutional Medicine
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• v.9 no.2
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• pp.163-173
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• 1997

Amp-FLP is a one of the most frequently used human genetic analysis methods which adopts STR and VNTR typings. In this study, 100 genomic DNA samples of Taeum, Soyang and Soum constitution group were analysed by Amp-FLP method. The allele distribution of three STR loci(TH01, vWA and CSF1PO) and one VNTR locus(MCT118) of each different constitution group were investigated and the allele distribution was statistically evaluated. It was found out that the allele distribution of MCT118 and THO1 loci was not significantly different among different constitutions. However, the allele distribution of vWA showed p-value of 0.02056(Soyang group) and $2.41{\times}10^{-10}$(Soum group) which is much lower than significant level of p-value 0.05. Also, p-value of CSF1PO in Soum group was found out to be $4.65{\times}10^{-17}$. Therefore, it is expected that vWA and CSF1PO loci can be used as an indicator for gnenetic difference of different constiturion if the same result is obtained with sufficient number of samples.

• Korean Journal of Ecology and Environment
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• v.40 no.1
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• pp.93-102
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• 2007

The runoff characteristics of organic matter in turbid water were investigated in eleven tributary streams of the Han River system, Korea. The flow-weighted event mean concentrations of organic matter ranged from 1.5 to 3.2 mg $L^{-1}$ of DOM and 2.2 of 29.1 mg $L^{-1}$ of POM, respectively. The SUVA value which reflects the proportion of humic substance in organic matters was higher during the rainfall season, meaning that the runoff of refractory form increase in this period. Stable carbon isotope ratios of both POM and DOM were different among streams, which reflect the sources of organic matter. DOM isotope ratios were less depleted of $^{13}C$ than that of POM by approximately 1 to $2%_{\circ}$ ${\delta}^{13}C$ of the several turbid streams (the Mandae Stream, the Jawoon Stream, and the Daegi stream) were heavier than those of clear streams. ${\delta}^{13}C$ values in the turbid upstream tributaries were similar to those of downstream reaches (such as the Soyang River, the Sum River, and the Seo River). From the ${\delta}^{13}C$ analysis of POM it could be calculated that $C_4$ pathway contributed approximately 15.9 to 23.6% of organic matter in several turbid upstream sites, and over 20% in the three sites of large downstream reaches. On the contrary it contributed only 9.1 to 12.8% in clear streams of forest watersheds. In the Soyang River, $C_4$ pathway organic matter contributed 8.8% of the DOM pool.

• Journal of Environmental Science International
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• v.7 no.4
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• pp.441-450
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• 1998

The purpose of this study is to evaluate and to predict of eutrophication in lakes by using VollenweiderGECD model and total phosphorus concentration and inflow rate which were measurded in 1993-1996. The results of study was as follows. The annual total phosphorus loading from the watershed was calculated to be 181-195tP /yr at lake Soyang, 591-680tP/yr at lake Chungju, 420-466tP/yr at lake Taechong, 229-278tP/yr at lake Andong, 103-106tP/yr at lake Hapchon, 57-59tP/yr at lake Imha, 194-244tP/yr at lake Namgang, 8386tP /yr at lake Chuam, 99-109tP /yr at lake Somjin. These are discharged, for the most parts, from population and ftshfarm facility. TP loading on the surface area at lake Soyang was 3.0lgP/$m^2$/yr, 2.82gP/$m^2$/yr, 2.84gP/$m^2$/yr, 3. 03gP/$m^2$/yr, at lake Chungju 7.91gP/$m^2$/yr, 6.87gP/$m^2$/yr, 7.38gP/$m^2$/yr, 7.l8gP/$m^2$/yr, at lake Taechong 6.7lgP/$m^2$/yr, 7.25gP/$m^2$/yr, 7.24gP/$m^2$/yr, 6.53gP/$m^2$/yr and TP loading on the surface area of Nakdong river basin, that is, lake Andong, Imha, Hapchon and Namgang were 5.39gP/$m^2$/yr, 4.47gP/$m^2$/yr, 4. 56gP/$m^2$/yr, 4.45gP/$m^2$/yr and 2.20gP/$m^2$/yr, 2.23gP/$m^2$/yr, 2.24gP/$m^2$/yr, 2.l7gP/$m^2$/yr and 4.50gP/$m^2$/ yr, 4.50gP/$m^2$/yr, 4.54gP/$m^2$/yr, 4.43gP/$m^2$/yr and 8.25gP/$m^2$/yr, 8.48gP/$m^2$/yr, 8.48gP/$m^2$/yr, 10. 39gP/$m^2$/yr respectively. Also those of lake Chuam was 2.51gP/$m^2$/yr, 2.61gP/$m^2$/yr, 2.52gP/$m^2$/yr, 2. 54gP/$m^2$/yr and TP loading on the surface area at lake Somjin was analysed 4.09gP/$m^2$/yr, 4.l0gP/$m^2$/yr, 3.98gP/$m^2$/yr,3.73gP/$m^2$/yr. The tropic states of nine lakes can be assessed as eutrophy because phosphorus loading exceeds the critical phosphorus loading by Vollenwelder-GECD model.

• Journal of Korea Water Resources Association
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• v.38 no.12 s.161
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• pp.1039-1049
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• 2005

The objective of this study is to produce optimal radar-derived rainfall for hydrologic utilization. The ground clutter and beam blockage effects from Mt. Kwanak station (E.L 608m) are removed from radar reflectivities by POD analysis. The reflectivities are used to produce radar rainfall data in the form of rain rates (mm/h) by the application of the Marshall-Palmer reflectivity versus rainfall relationship. However, these radar-derived rainfall are underestimated in temporal and spatial scale compared with observed one, so it is necessary to hire a correction scheme based on the gauge-to-radar (G/R) statistical adjustment technique. The selected watershed for studying the real-time correction of radar-rainfall estimation is the Soyang dam site, which is located approximately 100km east of Kwanak radar station. The results indicate that adjusted radar rainfall with the gauge measurement have reasonal G/R ratio ranged on 0.95-1.32 and less uncertainty with that mean standard deviation of G/R ratio are decreased by $9-28\%$. Mean areal precipitation from adjusted radar rainfall are well agreed to the observed one on the Soyang River watershed. It is concluded that the real-time bias adjustment scheme is useful to estimate accurate basin-based radar rainfall for hydrologic application.