Journal of Korean Medicine for Obesity Research (한방비만학회지)

The Society of Korean Medicine for obesity Research (한방비만학회)
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Can the Sasang Constitutional Type Trait Act as an Independent Risk Factor for Dyslipidemia?

사상체질이 이상지질혈증의 위험인자가 될 수 있는가?

  • Lee, Jiwon (Department of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Jang, Hyunsu (Department of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Park, Byungjoo (Department of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Euiju (Department of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Koh, Byunghee (Department of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Junhee (Department of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University)
  • 이지원 (경희대학교 한의과대학 사상체질과) ;
  • 장현수 (경희대학교 한의과대학 사상체질과) ;
  • 박병주 (경희대학교 한의과대학 사상체질과) ;
  • 이의주 (경희대학교 한의과대학 사상체질과) ;
  • 고병희 (경희대학교 한의과대학 사상체질과) ;
  • 이준희 (경희대학교 한의과대학 사상체질과)
  • Received : 2014.12.02
  • Accepted : 2014.12.15
  • Published : 2014.12.30
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Abstract

Objectives: This study was designed to investigate the correlation between Sasang constitution and dyslipidemia and the possibility that Sasang constitution can be a risk factor of dyslipidemia. Methods: This study was a retrospective cross-sectional study based on chart review. Seventeen thousand sixty-nine charts which were collected from May 2007 to June 2010 in International Healthcare Service Center, Kyung Hee University Medical Center, were reviewed for the study. Fifteen thousand two hundred fifty charts including Sasang constitutional diagnosis and lipid profiling were selected and we examined the correlation between Sasang constitution and dyslipidemia. Results: After adjusted for body mass index, the levels of total cholesterol and triglyceride were highest in Taeeum group, and lowest in Soeum group. High-density lipoprotein was highest in Soeum group, and lowest in Taeeum group. After adjusted for age, sex, and body mass index, the odds ratios for 'high triglyceride' were 1.716 (1.411~2.087) in Soyang group and 2.021 (1.650~2.475) in Taeeum group compared to Soeum group. The odds ratio for 'high low-density lipoprotein' was 1.229 (1.006~1.501) in Soyang group compared to Soeum group. The odds ratios for 'low high-density lipoprotein' were 1.195 (1.033~1.381) in Soyang group and 1.414 (1.212~1.649) in Taeeum group compared to Soeum group. Conclusions: The lipid profiles and dyslipidemic risk differed across constitutional types, showing constitution type-specific patterns, so that we could infer the possibility that Sasang constitutional types can be a risk factor of dyslipidemia.

목적: 본 연구는 사상체질과 이상지질혈증의 상관관계 및 사상체질이 이상지질혈증의 위험요인이 될 수 있는가를 탐색하는 데 목적이 있다. 방법: 본 연구는 의무기록을 바탕으로 한 후향적 단면조사연구로, 2007년 5월부터 2010년 6월까지 서울 소재 경희의료원 건강증진센터에 내원한 건강검진 수진자 17,069명의 의무기록을 조사하여 사상체질진단검사 결과 및 생화학검사 결과 등이 확인된 15,250명을 대상으로 사상체질과 이상지질혈증 간의 상관관계를 조사하였다. 결과: 총 콜레스테롤과 중성지방은 체질량지수(body mass index, BMI)를 보정한 상태에서 태음인, 소양인, 소음인 등의 순서로 높았고, 고밀도 콜레스테롤은 소음인, 소양인, 태음인 순서로 높았다. 연령, 성별, BMI 등을 보정한 상태에서 '높은 중성지방'에 대한 odds ratio는 소음인에 비해 소양인이 1.716 (1.411~2.087), 태음인이 2.021 (1.650~2.475)이었으며, '높은 저밀도콜레스테롤'에 대한 odds ratio는 소음인에 비해 소양인이 1.229 (1.006~1.501)였고, '낮은 고밀도 콜레스테롤'에 대한 odds ratio는 소음인에 비해 소양인이 1.195 (1.033~1.381), 태음인이 1.414 (1.212~1.649)였다. 결론: 사상체질에 따라 일부 이상지혈증의 분포 및 odds ratio에 유의한 차이가 있었고, 이에 따라 사상체질이 이상지질혈증의 위험요인이 될 수 있는 가능성을 찾을 수 있었다.

Keywords

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