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In vitro screening of elastase, collagenase, hyaluronidase, and tyrosinase inhibitory and antioxidant activities of 22 halophyte plant extracts for novel cosmeceuticals

  • Jiratchayamaethasakul, Chanipa;Ding, Yuling;Hwang, Ouibo;Im, Seung-Tae;Jang, Yebin;Myung, Seung-Won;Lee, Jeong Min;Kim, Hyun-Soo;Ko, Seok-Chun;Lee, Seung-Hong
    • Fisheries and Aquatic Sciences
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    • v.23 no.3
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    • pp.6.1-6.9
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    • 2020
  • Background: Halophyte plant (HPs), a salt-resistant flora, has been reported to provide several health benefits, but the knowledge of its cosmeceutical potential is still ambiguous. Here, 70% ethanol extracts of 22 HPs collected from along the coast of South Korea were investigated for their potentials of antioxidant, anti-aging, and whitening properties for use as materials in novel cosmeceuticals. Methods: Antioxidant activities were determined by DPPH (1,1-diphenyl-2-pricrylhydrazyl) free radical and hydrogen peroxide scavenging assays, and skin aging-related enzyme activities (anti-elastase, anti-collagenase, anti-hyaluronidase, and anti-tyrosinase) were evaluated by using the spectrophotometric method. Results: Among the 22 HPs, we found that Ischaemum antephoroides f. coreana and Atriplex gmelinii extracts presented the strongest scavenging effects against DPPH free radical and hydrogen peroxide, respectively. Our finding additionally suggested that Salicornia europaea extract might provide a major source of anti-elastase and anti-hyaluronidase; meanwhile, Rosa rugosa extract showed the highest anti-collagenase effect. Furthermore, the highest tyrosinase inhibitory activity was possessed by Spartina anglica extract. Conclusion: These findings may suggest that halophyte plants showing biological activities may be potent inhibitors of tyrosinase, elastase, collagenase, and hyaluronidase and could be useful for application in cosmeceuticals.

Quality Changes of Fresh Vegetable and Fruit Juice by Various Juicers (주스제조 장치에 따른 채소 및 과일 주스의 품질 변화)

  • Choi, Moon-Hee;Kim, Min-Joo;Jeon, Young-Jin;Shin, Hyun-Jae
    • KSBB Journal
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    • v.29 no.3
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    • pp.145-154
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    • 2014
  • A fresh vegetable and fruit juice has become a new healthy food available for detoxification, dieting and health. This paper presents the useful information about the quality changes of fresh juice according to different juicer. Quality of fresh juice could be evaluated by several factors such as juice yield, enzyme activity, antioxidant activity, polyphenol contents, and anti-inflammatory activity. The juice yields of 12 different vegetables and fruits were compared using 6 different juicers and it was observed that the yield of slow juicer was better than that of conventional blender. Among 12 samples, the juice yield of grape is the best and the pH of the juice was in the acidic range of 3 and 4. Kiwi and grapefruit were the best in terms of protease enzyme activities by Hemoglobin units on the tyrosine basis and Spectrophotometric acid protease unit and papain units on the tyrosine basis of KFDA protocols. The total polyphenol contents were also high in kiwi and grapefruit. The antioxidant activity by diphenyl-1-picrylhydrazyl (DPPH), superoxide dismutase (SOD), and radical scavenging assay were high in the order of kiwi, grapefruit, grape, tomato, and orange. Anti-inflammatory activities were also assay for 12 samples with 6 juicers. It can be concluded that of fresh fruit and vegetable juice provides a source of antioxidant components and enzymes with high activity. And the enzyme activities could be used as one of the quality indicator of fresh juice. Concerning the juicers used in this study, slow juicer could be recommended to prepare the fresh juice in terms of the juice quality.

A Study on Make-up Behavior and Cosmetics Purchasing Pattern of Male (남성의 화장행동과 화장품 구매에 관한 연구)

  • Lee, Il-Cheong;Choi, Eun-Me
    • Journal of the Korean Society of Fashion and Beauty
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    • v.2 no.2 s.2
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    • pp.34-47
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    • 2004
  • The objective of this study is to investigate the perception of males about make-up and the make-up process, analyze principal factors affecting their decision when purchasing cosmetics and, ultimately, to provide basic data for further survey and research into features of cosmetics and their satisfaction. The subjects of the study a.e male adults living in Jeonju, Iksan and Gunsan cities of Jeonbuk province. Surveyors made direct interviews with the subjects from October 21 to 30, 2003 and collected 174 questionnaires from them, which were subsequently put to the final analysis. The demographic characters of the surveyed showed that 60.9% of them were in the age ranging 30 to 39, 75.3% married, 69.5% undergraduates or graduates, 39.1% self-employed, 25.9% earning more than 3.01 million Won monthly and 43.7% spending less than 10,000 Won a month for cosmetics. Their make-up and purchasing pattern of cosmetics featured that 54.0% of the surveyed use cosmetics for skin care, 54.0% for cleanness and health, 84.5% for foundation(lotion or skin lotion) only, and 60.9% once a day. Out of the surveyed males, 79.3% haven't experienced any adverse side effects after make-up. Of those who experienced, 80.5% named disagreement of cosmetics with skin for the reason. As for kind or symptom of the side effects, 38.8% set forth itching. Among those who had aftermath or intoxication from make-up, 52.8% said they could recover naturally. According to the survey, 57.5% felt somewhat awkward after make-up, but not quite bad though. Thirty-seven point nine percent of the males surveyed replied they cared little about the purpose of male-oriented cosmetics. Quality was raised by 31.0% as the foremost issue to improve. Television turned out to be the main source for 56.9% of the surveyed to get information about cosmetics. For 56.35%, general discount shops are preferred to buy cosmetics and 24.7% of them take ones recommended by salespeople. When buying cosmetics, 47.1% considered color and fragrance most seriously.

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A Study on the Use of Complementary and Alternative Therapies in Korean Adults (한국 성인의 보완대체요법 이용에 관한 조사)

  • Lee, Keum Jae;Kim, Ok Hyun;Chun, Woo Jung;Roe, Myung Hee;Kang, Moon Jung;Ko, Sung Hee;Lee, Kyeong Suk;Lee, Ko Eun
    • Korean Journal of Adult Nursing
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    • v.19 no.1
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    • pp.144-154
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    • 2007
  • Purpose: This descriptive study was conducted to identify the use of complementary and alternative therapies, and the perception and attitudes toward CAT in Korean adults. Methods: The 1,010 study subjects were recruited from ten regions in South Korea. Data were collected from July to September, 2004. Results: The 43.2% of the sample(n=436) had an experience of using CAT. The subjects using CAT was more likely to have high score in the CAT perception compared to the subjects with no experience of CAT(p=.001). The primary source of information about CAT was mass media(59.7%). The 52.4% of the sample answered that CAT was supplementary and the 27.7% answered CAT was applicable to chronic pain or musculoskeletal disorders. Subjects(34.8%) pointed out that the greatest problem was no scientific informant in the use of CAT. The primary reason of using CAT was to maintain their health or to prevent disease(44.0%), and the 59.0% of the subjects responded that CAT was effective. Majority of subjects were satisfied with CAT(63.3%) and experienced no side effects of CAT(90.6%). Conclusion: This study suggests that professional counseling and education for CAT is needed for Korean public as well as the research approach to test the effects of CAT.

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Characteristics of elderly patients with acute poisoning (노인 중독 환자의 특성)

  • Kim, Bo-Kyeong;Jung, Si-Young;Jung, Koo-Young
    • Journal of The Korean Society of Clinical Toxicology
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    • v.8 no.2
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    • pp.61-68
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    • 2010
  • Purpose: Poisoning is a major health problem for the elderly, and poisoning can cause fatal side effects. However, the characteristics and clinical features of elderly patients with acute poisoning have not been well studied in the previous domestic research. So, we tried to analyze the clinical characteristics and toxic substances of the patients who were 65 years old or older and who were admitted to the regional emergency medical center due to acute poisoning. Methods: We retrospectively reviewed the medical records and poisoning protocols of the patients who were 65 years of age or older and who had with acute poisoning and who visited the ED in our emergency center from January 2005 to December 2009. We collected the demographic information, the gender, the underlying diseases, the causes and toxic substances, the initial presentation, the treatment and the outcomes. Results: A total of 2179 poisoned patients visited the hospital during 5 years, and among them 244 were 65 years of age or older (11.2%). The mean age was $75.6{\pm}6.9$ years and the male:female ratio was 1:1.7. The most common cause of poisoning was suicide (73.4%) and the most common source of poisonous substances was their own drugs. Of the substances used for poisoning, benzodiazepine was the most common drug (25.8%), followed by sedatives other than benzodiazepine (25.4%), insecticide (12.7%), chemical agents (12.3%) and herbicides (8.2%). The most common initial presentation was mental change (64.8%). When comparing the factors between the three elderly groups, there was no difference in gender, the cause, the substances and the underlying disease. The outcomes of treatment included ICU admission (56.1%), a good condition at discharge (12.7%) and admission to a general ward (12.7%). The overall mortality rate was 10.2% for the elderly patients. Conclusion: In this Korean study, unlike the foreign studies, the most common cause of poisoning in elderly patients was intentional poisoning. The admission rate was 68.8% and mortality rate was 10.2%.

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Patient experience and recommendation intention at specialty hospitals (전문병원 입원환자의 환자경험 및 추천의향)

  • Ji Eun Kim;Myung-ll Hahm;Kyounga Lee
    • Korea Journal of Hospital Management
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    • v.28 no.2
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    • pp.21-31
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    • 2023
  • Purposes: Patient experience is a tool to evaluate the process and results of medical services provided by medical institutions from the patient's point of view. Patient satisfaction surveys are a meaningful and essential source of information for improving quality in healthcare organizations. This study aims to provide basic data for improving the quality of medical service that patients can feel by analyzing the recommendation intention and satisfaction of inpatients in specialty hospitals. Methodology: The subjects of this study were 879 inpatients in 28 specialty hospitals in 14 designated fields. We conducted a telephone survey with a structured questionnaire on the satisfaction and recommendation intention for specialty hospitals. Findings: In inpatients, hospital satisfaction was higher in nursing care services and hospital satisfaction was low in physicians care services. The overall patient satisfaction score was 91.4(SD=11.9) out of 100, and the intention of recommendation was 92.0(SD=14.1) out of 100. The factors affecting patient experience were designated fields, sex, age, residential area, monthly household income, and perceived health status. Practical Implications: This study confirmed the high level of patient satisfaction and recommendation intention among inpatients of specialty hospitals. Patient satisfaction can be of great value to healthcare providers in recognizing and improving the quality of care, as well as predicting patients' willingness to revisit medical institutions. This study can be used to improve the quality of hospital care services in specialty hospitals rather than general and tertiary general hospitals.

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Basic Research for the Recognition Algorithm of Tongue Coatings for Implementing a Digital Automatic Diagnosis System (디지털 자동 설진 시스템 구축을 위한 설태 인식 알고리즘 기초 연구)

  • Kim, Keun-Ho;Ryu, Hyun-Hee;Kim, Jong-Yeol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.1
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    • pp.97-103
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    • 2009
  • The status and the property of a tongue are the important indicators to diagnose one's health like physiological and clinicopathological changes of inner organs. However, the tongue diagnosis is affected by examination circumstances like a light source, patient's posture, and doctor's condition. To develop an automatic tongue diagnosis system for an objective and standardized diagnosis, classifying tongue coating is inevitable but difficult since the features like color and texture of the tongue coatings and substance have little difference, especially in the neighborhood on the tongue surface. The proposed method has two procedures; the first is to acquire the color table to classify tongue coatings and substance by automatically separating coating regions marked by oriental medical doctors, decomposing the color components of the region into hue, saturation and brightness and obtaining the 2nd order discriminant with statistical data of hue and saturation corresponding to each kind of tongue coatings, and the other is to apply the tongue region in an input image to the color table, resulting in separating the regions of tongue coatings and classifying them automatically. As a result, kinds of tongue coatings and substance were segmented from a face image corresponding to regions marked by oriental medical doctors and the color table for classification took hue and saturation values as inputs and produced the classification of the values into white coating, yellow coating and substance in a digital tongue diagnosis system. The coating regions classified by the proposed method were almost the same to the marked regions. The exactness of classification was 83%, which is the degree of correspondence between what Oriental medical doctors diagnosed and what the proposed method classified. Since the classified regions provide effective information, the proposed method can be used to make an objective and standardized diagnosis and applied to an ubiquitous healthcare system. Therefore, the method will be able to be widely used in Oriental medicine.

Current Status and Future Directions of Management of Hazardous Air Pollutants in Korea - Focusing on Ambient Air Monitoring Issues - (우리나라 유해대기오염물질의 관리현황과 개선방향 - 환경대기 모니터링 문제를 중심으로 -)

  • Baek, Sung-Ok;Jeon, Chan-Gon
    • Journal of Korean Society for Atmospheric Environment
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    • v.29 no.5
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    • pp.513-527
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    • 2013
  • Recently, hazardous air pollutants (HAPs) have been of great concern in Korea, largely due to public awareness on the importance of their impacts on environmental health. A group of HAPs includes a large number of various chemicals such as VOCs, PAHs, PCBs, dioxines, furans, organochlorinated pesticides, and some heavy metals. These groups of pollutants are generally known to have genetic toxicity and to be persistent in the environment. In addition, most of chemicals belong to the category of HAPs are widely distributed not only in air, but also in water and soil environments, and has therefore undergone considerable scrutiny for the last three decades. In this article, environmental implications and management of HAPs in Korea will be reviewed, with a particular emphasis on the monitoring of HAPs in the ambient air. A number of field studies will be introduced, which were recently conducted in large urban and industrial areas. Based on the filed studies, eight pollutants have been suggested to be intensively managed as higher priority pollutants, which are benzene, 1,3-butadiene, formaldehyde, acrolein, trichloroethylene, benzo(a)pyrene, hexa-valent Cr, and $PM_{2.5}$. Finally, future directions for a mega scale project for comprehensive monitoring of ambient atmosphere in large urban areas will be suggested. Such an innovative project is believed to provide more realistic information on the nature of the population exposure, which can not be simply identified by emission inventories or source investigations. Therefore, any strategy for the management of HAPs should be developed by not only emission-based approaches, but also observation-based approaches.

The Growth Effects on Interior Landscape Plants by Optical Fiber Lighting System (광섬유 조명체계가 실내조경식물의 생육에 미치는 효과)

  • 최경옥;방광자
    • Journal of the Korean Institute of Landscape Architecture
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    • v.29 no.6
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    • pp.92-100
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    • 2002
  • This study was carried out to obtain fundamental information on the growth response of interior landscape plants under fluorescent light, sunlight and optical fiber lighting indoors. Saintpaulia ‘Delaware’, ‘Kalanchoe blossfeldiana, Anthurium scherzerianum and Ardisia crenata were examined using light intensity of 5001ux and 1,0001ux of fluorescent light, sunlight and optical fiber lighting in an interior environment. Results of experiments are as follows; 1) Plant growth status showed the best results under optical fiber lighting compared with fluorescent light or sunlight. 2) Plant growth status was better under 1,0001ux light intensity than 5001ux light intensity and in cases of the same light intensity, the highest growth increase was under optical fiber lighting. while it was showed relatively different according to the different plant species between a fluorescent light and sunlight. 3) The deep pinkish red color of Saintpaulia ‘Delaware’flower was obtained first under an optical fiber lighting and a fluorescent light, a sun light in that order. 4) Regarding interred activity, photosynthetic rate and transpiration rate, intercellular CO, water absorption rate showed a similar tendency generally in spite of a little difference. Namely, transpiration rate and intercellular CO, $CO_2$ a absorption rate increased according to increase of photosynthetic rate. 5) Photosynthetic rate of test plants except Anthurium scherzerianum increased according to increase of light intensity and increased highest under optical fiber lighting in the same light intensity condition. Increases differed under fluorescent light and sun light. That of Saineaulia ‘Delaware’and Anthurium scherzerianum increased in the order of optical fiber, fluorescent light and sun light, but that of Kalanchoe blossfeldiana and Ardisia pusilla increased in the order of optical fiber lighting, sun light and fluorescent light. Summing up these results, In visual value or internal health status of all experimental plants we obtained the highest result under an optical fiber lighting. Finally, we need to introduce an optical fiber lighting in interior landscape space as main light source.

Living Conditions of the Rural Elderly Women and Activities for Extra Income Promotion (농촌여성노인의 생활실태와 일감갖기 활동에 관한 연구)

  • 임평자;최규련
    • Korean Journal of Rural Living Science
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    • v.6 no.2
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    • pp.109-119
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    • 1995
  • The objectives of this study were 1) to identity the living conditions of old women at rural area, 2) to inquire of the activities for extra income 3) to Provide information on the social service program development for old rural women. Data were collected by interview with the questionaire from 396 old rural women in Korea. In analyzing data, $x^2$-test has been produced by S A S program package at Rural Development Administration. The major results were as follows ; 1. The average age was 69.7years old of the subjects, illiteracy was 54.1%, widows was 58.6%, and the 18.4% of elderly have led a solitary life. Also, the degree of health care was very low. 2. The source of living costs in most old rural women lay on agricultural income. Also, because of the educational expenditure for their children, etc., they led to poverty, and then could not provide for their old age. 3. In spite of the 60.4% of the old women did farming, a lot of them wishes to have a side job. The reasons why they wish to do a side job were making money, spending their time in working, being proud before their children, etc.. 4. According as they rely on their husband, the eldest son and his wife, for the psychological, physical, economical support, their position among family was low. Therefore, only the 43.3% of old women were satisfied with their life. 5. Finally, in the result of this case study, the old women, who particpate in the extra income promoting program, were satisfied with their rural life, and their social position were high rather than elswhere.

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