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http://dx.doi.org/10.1186/s41240-020-00149-8

In vitro screening of elastase, collagenase, hyaluronidase, and tyrosinase inhibitory and antioxidant activities of 22 halophyte plant extracts for novel cosmeceuticals  

Jiratchayamaethasakul, Chanipa (Department of Pharmaceutical Engineering, Soonchunhyang University)
Ding, Yuling (Department of Pharmaceutical Engineering, Soonchunhyang University)
Hwang, Ouibo (Department of Pharmaceutical Engineering, Soonchunhyang University)
Im, Seung-Tae (Department of Pharmaceutical Engineering, Soonchunhyang University)
Jang, Yebin (Department of Pharmaceutical Engineering, Soonchunhyang University)
Myung, Seung-Won (Department of Pharmaceutical Engineering, Soonchunhyang University)
Lee, Jeong Min (Department of Applied Research, National Marine Biodiversity Institute of Korea)
Kim, Hyun-Soo (Department of Applied Research, National Marine Biodiversity Institute of Korea)
Ko, Seok-Chun (National Marine Bio-Resources and Information Center, National Marine Biodiversity Institute of Korea)
Lee, Seung-Hong (Department of Pharmaceutical Engineering, Soonchunhyang University)
Publication Information
Fisheries and Aquatic Sciences / v.23, no.3, 2020 , pp. 6.1-6.9 More about this Journal
Abstract
Background: Halophyte plant (HPs), a salt-resistant flora, has been reported to provide several health benefits, but the knowledge of its cosmeceutical potential is still ambiguous. Here, 70% ethanol extracts of 22 HPs collected from along the coast of South Korea were investigated for their potentials of antioxidant, anti-aging, and whitening properties for use as materials in novel cosmeceuticals. Methods: Antioxidant activities were determined by DPPH (1,1-diphenyl-2-pricrylhydrazyl) free radical and hydrogen peroxide scavenging assays, and skin aging-related enzyme activities (anti-elastase, anti-collagenase, anti-hyaluronidase, and anti-tyrosinase) were evaluated by using the spectrophotometric method. Results: Among the 22 HPs, we found that Ischaemum antephoroides f. coreana and Atriplex gmelinii extracts presented the strongest scavenging effects against DPPH free radical and hydrogen peroxide, respectively. Our finding additionally suggested that Salicornia europaea extract might provide a major source of anti-elastase and anti-hyaluronidase; meanwhile, Rosa rugosa extract showed the highest anti-collagenase effect. Furthermore, the highest tyrosinase inhibitory activity was possessed by Spartina anglica extract. Conclusion: These findings may suggest that halophyte plants showing biological activities may be potent inhibitors of tyrosinase, elastase, collagenase, and hyaluronidase and could be useful for application in cosmeceuticals.
Keywords
Halophyte plants; Antioxidant; Skin aging-related enzyme activities; Cosmeceuticals;
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1 Aghaleh M, Niknam V, Ebrahimzadeh H, Razavi K. Effect of salt stress on physiological and antioxidative responses in two species of Salicornia (S. persica and S. europaea). Acta Physiol Plant. 2010;33:1261-70.   DOI
2 Asanka SKK, Park Y, Shanura FIP, Ann YS, Ko CI, Wang L, You JJ. Soft corals collected from Jeju Island inhibits the $\alpha$-MSH-induced melanogenesis in B16F10 cells through activation of ERK. Fish Aquatic Sci. 2018;21(21).
3 Carvalho IS, Cavaco T, Brodelius M. Phenolic composition and antioxidant capacity of six artemisia species. Ind Crops Prod. 2011;33(2):382-8.   DOI
4 Chanda SV, Moteriya P, Padaliya H, Rathod TN, Baravalia YK. Antioxidant and metal chelating activities of Lagenaria siceraria (Molina) Standl peel, pulp and aerial parts in relation to their total phenol and flavonoid content. Phcog J. 2015;7(1):64-73.   DOI
5 Chatatikun M, Chiabchalard A. Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity. BMC Complement Altern Med. 2017;17:487.   DOI
6 No JK, Soung DY, Kim YJ, Shim KH, Jun YS, Rhee SH, Yokozawa T, Chung HY. Inhibition of tyrosinase by green tea components. Life Sci. 1999;65(21):PL241-6.
7 Nanjo F, Goto K, Seto R, Suzuki M, Sakai M, Hara Y. Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical. Free Radic Biol Med. 1996;21(6):895-902.   DOI
8 Ndlovu G, Fouche G, Tselanyane M, Cordier W, Steenkamp V. In vitro determination of the anti-aging potential of four southern African medicinal plants. BMC Complement Altern Med. 2013;13:304.   DOI
9 Ng TB, He JS, Niu SM, Pi ZF, Shao W, Liu F, Zhao L. A gallic acid derivative and polysaccharides with antioxidative activity from rose (Rosa rugosa) flowers. J Pharm Pharmacol. 2004;56(4):20.
10 Olech M, Nowak R, Zaluski D, Kepusta I, Amarowicz R, Oleszek W. Hyaluronidase, acetylcholinesterase inhibiting potential, antioxidant activity, and LC-ESI-MS/MS analysis of polyphenolics of rose (Rosa rugosa Thunb.) teas and tinctures. Int J Food Prop. 2017;20(S1):S16-25.   DOI
11 Paliwal S, Fagien S, Sun X, Holt T, Kim T, Hee CK, et al. Skin extracellular matrix stimulation following injection of a hyaluronic acid-based dermal filler in a rat model. Plast Reconstr Surg. 2014;134(6):1224-33.   DOI
12 Palmer DM, Kitchin JS. Oxidative damage, skin aging, antioxidants and a novel antioxidant rating system. J Drugs Dermatol. 2010;9(1):11-5.
13 Peres PS, Terra VA, Guarnier FA, Cecchini R, Cecchini AL. Photoaging and chronological aging profile: understanding oxidation of the skin. J Photochem Photobiol B. 2011;103(2):93-7.   DOI
14 Dudonne S, Poupard P, Coutiere P, Woillez M, Richard T, Merillon JM, Vitrac X. Phenolic composition and antioxidant properties of poplar bud (Populus nigra) extract: individual antioxidant contribution of phenolics and transcriptional effect on skin aging. J Agric Food Chem. 2011;59(9):4527-36.   DOI
15 Chatatikun M, Yamauchi T, Yamasaki K, Aiba S, Chiabchalard A. Anti melanogenic effect of Croton roxburghii and Croton sublyratus leaves in $\alpha$-MSH stimulated B16F10 cells. J of Tradit Complement Med. 2019;9(1):66-72.   DOI
16 Choi EK, Guo H, Choi JK, Jang SK, Shin K, Cha YS, Choi Y, Seo DW, Lee YB, Joo SS, Kim YB. Extraction conditions of white rose petals for the inhibition of enzymes related to skin aging. Lab Anim Res. 2015;31(3):148-52.   DOI
17 Ding YL, Jiratchayamaethasakul C, Kim EA, Kim J, Heo SJ, Lee SH. Hyaluronidase inhibitory and antioxidant activities of enzymatic hydrolysate from Jeju Island red sea cucumber (Stichopus japonicus) for novel anti-aging cosmeceuticals. J Marine Bioscience Biotechnology. 2018;10(2):62-72.   DOI
18 Bauman L. CosmoDerm/CosmoPlast (human bioengineered collagen) for the aging face. Facial Plast Surg. 2004;20:125-8.   DOI
19 Fulop T, Khalil A, Larbi A. The role of elastin peptides in modulating the immune response in aging and age-related diseases. Pathol Biol. 2012;60(1):28-33.   DOI
20 Heo SJ, Park EJ, Lee KW, Jeon YJ. Antioxidant activities of enzymatic extracts from brown seaweeds. Bioresour Technol. 2005;96(14):1613-23.   DOI
21 Horng CT, Wu HC, Chiang NN, Lee CF, Huang YS, Wang HY, Yang JS, Chen FA. Inhibitory effect of burdock leaves on elastase and tyrosinase activity. Exp Ther Med. 2017;14(4):3247-52.   DOI
22 Siedle B, Cisielski S, Murillo R, Loser B, Castro V, Klaas CA, Hucke O, Labahn A, Melzig MF, Merfort I. Sesquiterpene lactones as inhibitors of human neutrophil elastase. Bioorg Med Chem. 2002;10(9):2855-61.   DOI
23 Popoola OK, Marnewick JL, Rautenbach F, Ameer F, Iwuoha EI, Hussein AA. Inhibition of oxidative stress and skin aging-related enzymes by prenylated chalcones and other flavonoids from Helichrysum teretifolium. Molecules. 2015;20(4):7143-55.   DOI
24 Qin P, Xie M, Jiang Y. Spartina green food ecological engineering. Ecol Eng. 1998;11:147-56.   DOI
25 Sahasrabudhe A, Deodhar M. Anti-hyaluronidase, anti-elastase activity of Garcinia indica. Int J Botany. 2010;6:299-303.   DOI
26 Thring TS, Hili P, Naughton DP. Anti-collagenase, anti-elastase and antioxidant activities of extracts from 21 plants. BMC Complement Altern Med. 2009;9:27.   DOI
27 Tu PTB, Tawata S. Anti-oxidant, anti-aging, and anti-melanogenic properties of the essential oils from two varieties of Alpinia zerumbet. Molecules. 2015;20:16723-40.   DOI
28 Varani J, Fisher GJ, Kang S, Voorhees JJ. Molecular mechanisms of intrinsic skin aging and retinoid-induced repair and reversal. J Investig Dermatol Symp Proc. 1998;3(1):57-60.   DOI
29 Wang L, Lee W, Oh JY, Cui YR, Ryu B, Jeon YJ. Protective effect of sulfated polysaccharides from Celluclast-assisted extract of Hizikia fusiforme against ultraviolet B-induced skin damage by regulating NF-${\kappa}B$, AP-1, and MAPKs signaling pathways in vitro in human dermal fibroblasts. Mar Drugs. 2018;16(7):239.   DOI
30 Wittenauer J, Mackle S, Sussmann D, Schweiggert-Weisz U, Carle R. Inhibitory effects of polyphenols from grape pomace extract on collagenase and elastase activity. Fitoterapia. 2015;101:179-87.   DOI
31 Kendall AC, Nicolaou A. Bioactive lipid mediators in skin inflammation and immunity. Prog Lipid Res. 2013;52(1):141-64.   DOI
32 Jdey A, Falleh H, Ben JS, Mkadmini HK, Dauvergne X, Magne C, Krouri R. Antiaging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents. EXCLI J. 2017;16:755-69.
33 Jegasothy SM, Zabolotniaia V, Bielfeldt S. Efficacy of a new topical nanohyaluronic acid in humans. J Clin Aesthet Dermatol. 2014;7(3):27-9.
34 Kang M, Park S-H, Oh SW, Lee SE, Yoo JA, Nho YH, et al. Anti-melanogenic effects of resorcinol are mediated by suppression of cAMP signaling and activation of p38 MAPK signaling. Biosci Biotechnol Biochem. 2018;82(7):1188-96.   DOI
35 Kim JW, Um M, Lee JW. Antioxidant activities of hot water extracts from different parts of Rugosa rose (Rosa rugosa thunb.). J Korean Wood Sci and Technol. 2018;46(1):38-47.   DOI
36 Kim M, Hyun JM, Kim SS, Seong KC, Lim CK, Kang JL, et al. In vitro screening of subtropical plants cultivated in Jeju Island for cosmetic ingredients. Orient J Chem. 2016;32:807-15.   DOI
37 Kim MJ, Park MH, Jeong MK, Yeo JD, Cho WI, Chang PS, Chung JH, Lee JH. Radical scavenging activity and anti-obesity effects in 3T3-L1 preadipocyte differentiation of Ssuk (Artemisia princeps Pamp.) extract. Food Sci Biotechnol. 2010;19(2):535-40.   DOI
38 Ko EY, Kim DK, Roh SW, Yoon WJ, Jeon YJ, Ahn G. Kim NK Evaluation on antioxidant properties of sixteen plant species from Jeju Island in Korea. EXCLI J. 2015;14:133-45.
39 Kupeli E, Kartal M, Aslan S, Yesilada E. Comparative evaluation of the antiinflammatory and antinociceptive activity of Turkish Eryngium species. J Ethnopharmacol. 2006;107(1):32-7.   DOI
40 Won KJ, Lee KP, Baek S, Cui L, Kweon M-H, Jung SH, Ryu YK, Hong JM, Cho EA, Shin HS, Kim B. Desalted Salicornia europaea extract attenuated vascular neointima formation by inhibiting the MAPK pathway-mediated migration and proliferation in vascular smooth muscle cells. Biomed Pharmacother. 2017;94:430-8.   DOI
41 Yang EJ, Hyun J, Lee NH, Hyun CG. In vitro screening of Korean halophytes for cosmeceutical ingredients. Int J Chemtech Res. 2016;9(8):541-7.
42 Youwei Z, Yonghong P. Changes in antioxidant activity in Rosa rugosa flowers at different stages of development. N Z J Crop Hortic Sci. 2007;35(4):397-401.   DOI
43 Zheng J, Yu X, Maninder M, Xu B. Total phenolics and antioxidants profiles of commonly consumed edible flowers in China. Int J Food Prop. 2018;21(1):1524-40.   DOI
44 Lee JM, Yim MJ, Choi G, Lee MS, Park YG, Lee DS. Antioxidant and anti-inflammatory activity of six halophytes in Korea. Nat Prod Sci. 2018a;24(1):40-6.   DOI
45 Leach JB, Kathryn AB, Charles WPJ, Christine ES. Photocrosslinked hyaluronic acid hydrogels: natural, biodegradable tissue engineering scaffolds. Biotechnol Bioeng. 2003;82(5):578-89.   DOI
46 Lee HJ, Pan CH, Kim ES, Kim CY. Online high performance liquid chromatography (HPLC)-ABTS+ based assay and HPLC-electrospray ionization mass spectrometry analysis of antioxidant phenolic compounds in Salsola komarovii. J Korean Soc Appl Biol Chem. 2012;55(2):317-21.   DOI
47 Lee JH, Renita M, Fioritto RJ, St. Martin SK, Schwartz SJ, Vodovotz Y. Isoflavone characterization and antioxidant activity of Ohio soybeans. J Agric Food Chem. 2004;52(9):2647-51.   DOI
48 Lee JM, Yim MJ, Lee DS, Lee MS, Park YG, Jeon JH, Choi G. Comparison of biological activities of Korean halophytes. Nat Prod Sci. 2018b;24(4):247-52.   DOI
49 Liyanaarachchi GD, Samarasekera JKRR, Mahanama KRR, Hemalal KDP. Tyrosinase, elastase, hyaluronidase, inhibitory and antioxidant activity of Sri Lankan medicinal plants for novel cosmeceuticals. Ind Crops Prod. 2018;111:597-605.   DOI
50 Meot-Duros L, Le FG, Magne C. Radical scavenging, antioxidant and antimicrobial activities of halophytic species. J Ethnopharmacol. 2008;116(2):258-62.   DOI
51 Moon JY, Yim EY, Song G, Lee NH, Hyun CG. Screening of elastase and tyrosinase inhibitory activity from Jeju Island plants. EurAsia J BioSci. 2010;4:41-53.
52 Muller HE. Detection of hydrogen peroxide produced by microorganisms on an ABTS peroxidase medium. Zentralbl Bakteriol Mikrobiol Hyg A. 1985;259(2):151-4.