• Title/Summary/Keyword: Source activity

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Analysis of Accuracy of Apparent Activity According to Calibration Method for High Dose Rate Brachytherapy Source (측정용 전리함에 따른 고 선량율 근접치료용 방사성 선원의 겉보기 활성도의 정확도 비교 분석)

  • Huh, Hyun-Do;Choi, Jin-Ho;Choi, Sang-Hyoun;Kim, Seong-Hoon;Kim, Woo-Chul;Kim, Hun-Jeong;Lee, Re-Na;Kim, Kum-Bae;Hong, Seong-Eon;Shin, Dong-Oh
    • Progress in Medical Physics
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    • v.19 no.4
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    • pp.305-312
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    • 2008
  • The aim of this study is to introduce the accuracy of Ir-192 source's apparent activity using the well-type chamber and the Farmer-type ionization chamber in the high dose rate brachytherapy. We measured the apparent activity of Ir-192 that each medical center in the country has and the apparent activity of calibration certificate provided by manufacturer is compared with that by our experimental measurement. The number of sources used for the activity comparison was 5. The accuracy of the measured activity was in the range of -2.8% to -1.0% and -2.1% to 0.2% for the Farmer-type chamber system (Jig) and for the well-type, respectively. The maximum difference was within 1.0% for comparison with two calibration's tool. Our results demonstrate that well-type chamber as wall as Farmer-type chamber is a appropriate system as the routine source calibration procedures in HDR brachytherapy. Whenever a new source is installed to use in clinics, by periods, a source calibration should be carried out.

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Optimum Condition of Marine Actinomycetes, Streptomyces sp. NS 13239 for Growth and Producing Antibiotics

  • Shin Il-Shik;Lee Jung-Mo;Park Uk-Yeon
    • Fisheries and Aquatic Sciences
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    • v.3 no.3_4
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    • pp.217-221
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    • 2000
  • In previous study, marine actinomycetes producing the antibiotics were investigated to invent new antibiotics from east coast of Korea. The optimum growth conditions of Streptomyces sp. NS 13239 were $28^{\circ}C$, pH 7.0 and $3\%$ of NaCl concentration in various media. Streptomyces sp. NS 13239 showed strong antimicrobial activity against gram-positive bacteria, specially Methicillin resistant Staphylococcus aureus (MRSA), but just weak antimicrobial activity against yeasts and mold. On the other hand, it did not show antimicrobial activity against gram-negative bacteria. The optimum conditions for producing antibiotics were almost consistent with optimum growth conditions except carbon source and nitrogen source.

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Electrodermal Activity as an Indicator of Emotional Processes

  • Boucsein, Wolfram
    • Science of Emotion and Sensibility
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    • v.2 no.1
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    • pp.1-25
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    • 1999
  • The differentiation of emotions by means of psychophysiological measures has been only moderately successful so far. A major reason for this dilemma may be the lack of appropriate neurophysiological modeling for the various autonomic nervous system based measures being used in emotion research. The aim of the present article is to provide such a neurophysiological background for electrodermal activity which has been frequently used as an indicator of emotional processes. First, the literature is reviewd with respect to the usability of electrodermal measures as an indicators of emotion. second, the neurophysilogical sources of electrodermal phenomena in general are described. Electrodermal activity has different origins in the central nervous system, a limbic-hypothalamic source that dominates during negative emotions as opposed to a premotor and basal ganglia source being predominantly active during positive emotions. Panksepp's model of four basic emotive systems is adopted for demonstrating subcortical structures and pathways possibly involved in the elicitation of both kinds of electrodermal activity in comparison with cardiovascular in dicators of emotional processes.

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A detector system for searching lost γ-ray source

  • Khan, Waseem;He, Chaohui;Cao, Yu;Khan, Rashid;Yang, Weitao
    • Nuclear Engineering and Technology
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    • v.52 no.7
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    • pp.1524-1531
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    • 2020
  • The aim of this work is to develop a Geiger-Muller (GM) detector system for robot to look for a radioactive source in case of a nuclear emergency or in a high radiation environment. In order to find a radiation source easily, a detector system, including 3 detectors, was designed to search γ-ray radiation sources autonomously. First, based on GEANT4 simulation, radiation dose rates in 3 Geiger-Muller (GM) counters were simulated at different source-detector distances, distances between detectors and angles. Various sensitivity analyses were performed experimentally to verify the simulated designed detector system. A mono-energetic 137Cs γ-ray source with energy 662 keV and activity of 1.11 GBq was used for the observation. The simulated results were compared with the experimental dose rate values and good agreements were obtained for various cases. Only based on the dose rates in three detectors, the radiation source with a specific source activity and angle was localized in the different location. A method was adopted with the measured dose rates and differences of distances to find the actual location of the lost γ-ray source. The corresponding angles of deviation and detection limits were calculated to determine the sensitivity and abilities of our designed detector system. The proposed system can be used to locate radiation sources in low and high radiation environments.

Optimum Conditions for the Production of Keratinase by Bacillus sp. KN-517 and Application to the Degradation of Hair (Bacillus sp. KN-517에 의한 keratinase의 생산 최적 조건과 모발분해에 적용)

  • Kim, Hye-Sook;Shim, Kyu-Nam;Kang, Sang-Mo
    • KSBB Journal
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    • v.25 no.3
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    • pp.230-238
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    • 2010
  • A microbial strain having high keratinase activity was isolated from the soil of poultry factories of Gyeonggi or Chungcheong-do. The isolated strain was identified as Bacillus sp. based on its morphological and biochemical characteristics. In this study, the optimal conditions for the production of keratinase by this strain were investigated. The optimal medium composition for the keratinase production was determined to be 3.5% chicken feather as carbon source, 1.0% tryptone as organic nitrogen source, 1.0% $KNO_3$ as inorganic nitrogen source and 0.05% KCl, 0.05% $KH_2PO_4$, 0.03% $K_2HPO_4$ as mineral source and 0.01% yeast extract as growth factor. The optimal temperature and pH was $40^{\circ}C$ and 8.5 with shaking culture (200 rpm), respectively. The maximum keratinase production reached to 123 units/ml after 42 hr of cultivation under the optimal condition. When the hair was used as the sole carbon source, the maximum enzyme activity was 88 units/ml after 120 hr and in this case, the hair added in the medium was not degraded completely but got thinner than the control by 20%.

Development of the vac Source Profile using Collinearity Test in the Yeosu Petrochemical Complex (여수석유화학산단의 공선성 시험을 이용한 VOC 오염원 분류표 개발)

  • Jeon Jun-Min;Hur Dang;Hwang In Jo;Kim Dong-Sul
    • Journal of Korean Society for Atmospheric Environment
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    • v.21 no.3
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    • pp.315-327
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    • 2005
  • The total of 35 target VOCs (volatile organic compounds), which were included in the TO-14, was selected to develop a VOCs' source profile matrix of the Yeosu Petrochemical Complex and to test its collinearity by singular value decomposition(SVD) technique. The VOCs collected in canisters were sampled from 12 different sources such as 8 direct emission sources (refinery, painting, wastewater treatment plant, incinerator, petrochemical processing, oil storage, fertilizer plant, and iron mill) and 4 general area sources (gasoline vapor emission, graphic art activity, vehicle emission, and asphalt paving activity) in this study area, and then those samples were analyzed by GC/MS. Initially the resulting raw data for each profile were scaled and normalized through several data treatment steps, and then specific VOCs showing major weight fractions were intensively reviewed and compared by introducing many other related studies. Next, all of the source profiles were tested in terms of degree of collinearity by SVD technique. The study finally could provide a proper VOCs' source profile in the study area, which can give opportunities to apply various receptor models properly including chemical mass balance (CMB).

Phosphate and Carbon Source Regulation of Alkaline Phosphatase and Phospholipase in Vibrio vulnificus

  • Oh, Wan-Seok;Im, Young-Sun;Yeon, Kyu-Yong;Yoon, Young-Jun;Kim, Jung-Wan
    • Journal of Microbiology
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    • v.45 no.4
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    • pp.311-317
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    • 2007
  • In this study, the effects of phosphate concentration and carbon source on the patterns of alkaline phosphatase (APase) and phospholipase (PLase) expression in Vibrio vulnificus ATCC 29307 were assessed under various conditions. The activities of these enzymes were repressed by excess phosphate (4 mM) in the culture medium, but this repression was reversed upon the onset of phosphate starvation in low phosphate defined medium (LPDM) containing 0.2 mM of phosphate at approximately the end of the exponential growth phase. The expressions of the two enzymes were also influenced by different carbon sources, including glucose, fructose, maltose, glycerol, and sodium acetate at different levels. The APase activity was derepressed most profoundly in LPDM containing fructose as a sole carbon source. However, the repression/derepression of the enzyme by phosphate was not observed in media containing glycerol or sodium acetate. In LPDM-glycerol or sodium acetate, the growth rate was quite low. The highest levels of PLase activity were detected in LPDM-sodium acetate, followed by LPDM-fructose. PLase was not fully repressed by high phosphate concentrations when sodium acetate was utilized as the sole carbon source. These results showed that multiple regulatory systems, including the phosphate regulon, may perform a function in the expression of both or either APase and PLC, in the broader context of the survival of V. vulnificus.

Effects of Mixed Carbon Sources on the Production of Cellulase by Trichoderma reesei (Trichoderma reesei를 이용한 섬유소 분해 효소의 생산에 있어서 혼합탄소원의 영향)

  • Nam, Joo-Heon;Koo, Yoon-Mo;Yun, Hyun-Shik
    • The Korean Journal of Mycology
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    • v.26 no.2 s.85
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    • pp.239-245
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    • 1998
  • The feasibility of enzymatic hydrolysis of cellulosic materials is dependent on the cost of cellulase, which is strongly influenced by the selection of proper carbon source in the cellulase production medium. When solka floc was used as a carbon source for the production of cellulase by Trichoderma reesei Rut C-30, a maximum of 53.2 U/ml of CMCase activity (4.8 U/ml of FPase activity) was obtained with a concentration of 1 % of solka floc. The cellulase activity decreased to 50% in the presence of 0.5% of glucose in the medium. The production of cellulase was considerably enhanced when solka floc and wheat bran were used together as a carbon source. A medium which contained 1 % of solka floc and 3 % of wheat bran yielded highest cellulase activity: CMCase activity of 76 U/ml and FPase activity of 12.5 U/ml.

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The Comparison of Color and Physiological Properties of Hizikia fusiformis Cooking Juice Ethanol Extract Irradiated with Gamma Ray and Electron Beam (감마선 및 전자선 조사에 따른 톳 자숙액 에탄올 추출물의 색상 및 생물학적 활성 변화 비교)

  • Choi, Jong-Il;Kim, Hyun-Joo
    • KSBB Journal
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    • v.27 no.3
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    • pp.195-198
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    • 2012
  • This study was carried out to assess the effect of radiation on the changes of Hizikia fusiformis cooking juice ethanol extract and to compare the effect of gamma ray and electron beam. On the applying radiation, the dark color of cooking juice became changed with higher brightness and lower redness and yellowness. But, there was no difference between gamma ray radiation and electron beam radiation. 1,1-Diphenyl-2-picryl-hydrazyl radical scavenging activity and tyrosinase inhibitory activity of cooking juice were shown to be increased by radiation independent on the radiation source types. The reason for the increased biological activities was caused by higher content of total phenolic compounds. The results could be applied to investigate the effect of radiation source on the color and antioxidant activity of biomaterials, and it was thought that irradiation could be an promising method for enhancing the biological activity of biomaterials.

Effects of Temperature and Culture Media Composition on Sporulation, Mycelial Growth, and Antifungal Activity of Isaria javanica pf185

  • Lee, Jang Hoon;Lee, Yong Seong;Kim, Young Cheol
    • Research in Plant Disease
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    • v.27 no.3
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    • pp.99-106
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    • 2021
  • The fungal isolate Isaria javanica pf185 has potential as a mycopesticide because it demonstrates insecticidal activity against the green peach aphid and antifungal activity against Colletotrichum gloeosporioides. For commercialization of this isolate, determination of the optimal and least expensive culture conditions is required; however, these data are not currently available. This study describes the conditions for optimal development of conidia and production of metabolites for the biocontrol of the fungal pathogen. The optimal culture conditions were examined using cultures on solid agar and liquid media. High growth temperature enhanced spore formation but reduced antifungal activity in both solid and liquid media. The highest spore yield was obtained in a medium containing glucose as a carbon source and yeast extract as a nitrogen source. Soybean powder and wheat bran were effective nitrogen sources that promoted spore production and antifungal activity of the isolate. These results revealed the basic, cost-effective growth media for commercial production of a biopesticide with insecticidal and antifungal properties for use in integrated pest management.