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검색결과 338건 처리시간 0.019초

Development and Validation of HPLC-PDA Method and Pattern Recognition Analyses Using Eight Marker Compounds for the Quality Control Between the Seeds of Cuscuta chinensis Lam. and Cuscuta japonica Choisy

  • Nguyen, Duc Hung;Zhao, Bing Tian;Le, Duc Dat;Ma, Eun Sook;Min, Byung Sun;Woo, Mi Hee
    • Natural Product Sciences
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    • 제25권4호
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    • pp.334-340
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    • 2019
  • Cuscuta chinensis Lam. and Cuscuta japonica Choisy are parasitic plants. C. chinensis seeds were traditionally used for treatment of kidney and liver deficiencies. C. japonica seeds were used as tonic medicine to improve liver function and strengthen kidneys, treatment of high blood pressure, chronic diarrhea, and sore eyes. Cuscutae Semen are seeds of only C. chinensis in Korean Herbal Pharmacopoeia (K.H.P.). The developed HPLC-PDA method easily, accurately, and sensitively quantified using eight marker compounds [hyperoside (1), astragalin, (2), quercetin (3), kaempferol (4), chlorogenic acid (5), 3,4-di-O-caffeoylquinic acid (6), 1,5-di-O-caffeoylquinic acid (7), and 4,5-di-O-caffeoylquinic acid (8)]. In addition, the method may be used to distinguish seeds between C. chinensis Lam. and C. japonica Choisy. Furthermore, the result from the current study was applied to clarify samples between steam processed and unprocessed samples of C. chinensis by pattern analysis.

저출력 레이저 요법 및 침 치료를 이용한 반흔성 탈모 및 원형탈모증에 대한 치험 1례 (Case Study on Treating Scarring alopecia and Alopecia arreata Using Low Level Laser Therapy and Acupuncture)

  • 김철윤;서형식;이득주;권강
    • 한방안이비인후피부과학회지
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    • 제29권4호
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    • pp.182-188
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    • 2016
  • Objectives : The purpose of this study is to report the effect of low level laser therapy and acupuncture on hair loss. Methods : The patient with alopecia caused by bed sore and alopecia areata was treated with 29 times of laser therapy, acupuncture and took herbal medicine during about 3 months. The treatment effect was evaluated by standardized photography. Results : Hair loss had shown a marked improvement. Entire scalp had been replaced with new hairs. Conclusions : LLLT(low level laser therapy) is effective method for treating alopecia. It can shorten the length of treatment of alopecia.

자동차 정비공의 혈액 및 뇨검사 소견과 자각증상에 대한 조사 (Laboratory Findings and Subjective Symptoms of Car Repair Workers)

  • 이광성;이명구;조영채
    • 한국환경보건학회지
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    • 제24권2호
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    • pp.80-87
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    • 1998
  • To evaluate the effects on health by exposure to low dose organic solvents, the author analyzed the air concentration of mixed organic solvents (toluene, xylene, butylacetate) at worker's breathing zone during painting, some laboratory findings of blood (WBC, RBC, Hb, Hct, SGOT, SGPT, TC, TG, HDL-C, LDL-C, IgG, IgM, IgA and IgE) and urine (hippuric acid, urinary protein, urobilinogen), surveyed the subjective symptoms those were obtained from 35 male workers exposed to mixed organic solvents, and 25 male workers not exposed to organic solvents who worked in car repair workshops in Taejon area from December 1, 1995, to February 29, 1996. The results were as follows: 1. The mean concentration of urinary hippuric acid of car painting worker group (organic solvent exposure group) was 0.76$\pm$ 0.21 g/l, which is significantly higher than that of non-exposed group. 2. In hematologic findings, the values of RBC, TC, LDL-C, IgG and IgE in the exposure group were significantly lower than those of the nonexposed group, but SGOT and SGPT in the exposure group were significantly higher than those of the non-exposed group. 3. Urinary hippuric acid levels showed positively correlated with toluene, urobilinogen and HDL-C levels, but those were negatively correlated with RBC, LDL-C, IgM levels. 4. Rates of the subjective symptoms such as "dizziness", "appetite loss", "weight loss", "palpitation", "chest tightness", "sore throat and eye discomfort", "tingling sense and acrodynia", "illusion or hallucination" and "decreaased motor power" were significantly higher in the exposure group than those of the non-exposed group.

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방사선치료를 받는 암환자의 급성 부작용과 피로의 변화 (Changes in Side Effects and Fatigue of Cancer Patients Receiving Radiation Therapy)

  • 박경순
    • 종양간호연구
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    • 제2권1호
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    • pp.72-82
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    • 2002
  • Purpose : To observe changes in side effects and fatigue of the cancer patients receiving radiation therapy on the head/neck and the chest over a period from the start to the end of the therapy, and to analyze correlation between side effects and fatigue. Method : Twenty seven patients receiving radiation therapy 5 days per week for longer than 6 weeks participated in the present study. Fatigue was measured for when healthy, before-, and after-therapy. Side effects was surveyed by structured questionnaire on the last day of each therapy. Result : The results of this study were as follows. 1. Major side effects of the head/neck patients were skin irritation, change of taste, sore throat and xerostomia, while the chest patients experienced fatigue, skin irritation, anorexia, difficulty swallowing and cough increased with therapy. 2. Although fatigue was significantly changed for when healthy and before-therapy (F=60.25, p <.05) and also for before- and after-therapy, no statistical significance was demonstrated in fatigue of both the chest head/neck patients (p> .05). 3. Fatigue and side effects showed high correlation form the 4-th week with after the therapy Conclusion : The present results could be of great use to develop systematic intervention technique, leading to practical help for patients, since side effects and fatigue change to a large degree depending on the disease and the timing and technique of the therapy.

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"조선왕조실록"에 나타난 주요 외용제에 대한 고찰 (Consideration on the Paste Preparation Based on Entries from the Annals of the Chosun Dynasty)

  • 방성혜;차웅석;김남일
    • 대한한의학회지
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    • 제30권4호
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    • pp.37-46
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    • 2009
  • Objectives: The purpose of this study was to investigate the external application of paste preparation recorded in the Annals of the Chosun Dynasty (朝鮮王朝實錄) and to clarify the significance of modern use of plaster therapy. Methods: Of many paste preparations, records of All-applying ointment (萬應膏), One-great ointment (太一膏), Pain-relieving plaster (救苦膏), and Pus-promoting powder (促膿膏) were especially examined from the Annals of the Chosun Dynasty. Other medical records regarding how these preparations were passed onto later generations were also studied. Results: According to the records from the Annals of the Chosun Dynasty, paste preparations were mainly used to cure abscess and sore, partly to treat pain diseases. From other medical documents, it could be found that these preparations were continuously used in subsequent eras. Conclusions: From these records, the level and features of Chosun Dynasty medicine could be speculated. It is necessary to find and restore effective paste preparations in Traditional Korean Medicine to use for treating disease today. Therefore, records from the Annals of the Chosun Dynasty are important and meaningful materials.

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특발성(特發性) 간질(癎疾) 환아(患兒) 치험(治驗) 1례(例) (The Clinical Study on 1 Case of Patient with Idiopathic Epilepsy)

  • 이정림;신지나;송인선
    • 대한한방소아과학회지
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    • 제17권2호
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    • pp.27-35
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    • 2003
  • 특발성(特發性) 간질(癎疾)을 진단받고 지속적인 경련(痙攣)을 주소(主訴)로 내원한 환아(患兒)의 치료에 소양인(少陽人) 형방도적산(荊防導赤散) 가미방(加味方)과 철치료(鍼治療)를 병행하여 경련과 제반증상을 완화하는데 양호(良好)한 효과를 보았다. 비록 현재 경련이 나타나지 않고 있지만, 아직 증상이 남아 있는 상태이고 치료과정이 길지 않았으므로, 향후 지속적인 경과관찰이 필요하리라 사료된다.

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소염약침과 탁리소독음의 복합 치료를 이용한 4도 욕창 환자 치험 2례 (Two Cases of Grade Four Pressure Ulcer Patients Treated with Pharmacopuncture Soyeom and Herbal Medicine Taklisodok-eum)

  • 이대현;남지성;정현숙;장인수;서의석
    • 대한한방내과학회지
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    • 제31권2호
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    • pp.388-394
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    • 2010
  • Objectives : This study reports two cases of grade four pressure ulcer patients mainly treated by pharmacopuncture Soyeom and Taklisodok-eum. Methods : Two patients with grade four pressure ulcers at the oriental medicine hospital of Woosuk University were treated by pharmacopuncture Soyeom and herbal medicine Taklisodok-eum. Soyeom was treated once a day and Taklisodok-eum was given three times a day. We then observed the patients' appearances of pressure ulcer and changes of blood test results. Results and Conclusions : After ten days or three months each, wound sizes were reduced, tissue regeneration was accelerated and blood tests were improved. In conclusion, it is our belief that pharmacopuncture and herb medicine are effective to treat grade four pressure ulcers, and future studies will be required to ascertain this method on grade four pressure ulcers.

백혈병세포주 Jurkat의 세포주기 억제에 미치는 합환피(Albizzia julibrissin) 물 추출물의 효과 (Effect of the Water Extract of Albizzia julibrissin on Cell Cycle Progression in the Human Leukemic Jurkat Cells)

  • 황상구;이형철;김대근;안원근;전병훈
    • 생약학회지
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    • 제33권1호통권128호
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    • pp.29-34
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    • 2002
  • Albizzia julibrissin belonging to the family Leguminosae has been used for the treatment of contusion, sore throat, amnesia, and insomnia in Oriental traditional medicine. The water extract of A. julibrissin induced apoptosis in Jurkat T-acute lymphoblastic leukemia (ALL) cells as measured by cell morphology. The capability of this herb medicine to induce apoptosis was associated with proteolytic cleavage of specific target protein such as beta-catenin protein suggesting the possible involvement of caspases. The purpose of the present study is also to investigate the effect of A. julibrissin on cell cycle progression. Our results showed that GI checkpoint related gene products (cyclin D1, cyclin dependent kinase 4, retinoblastoma, E2F1) were decreased in their protein levels in a dose-dependent manners after treatment of the extract. These results indicate that the increase of apoptotic cell death by A. julibrissin may be due to the inhibition of cell cycle progression in wild type p53-lacking Jurkat cells.

A Retrospective Review of Iatrogenic Skin and Soft Tissue Injuries

  • Lee, Tae Geun;Chung, Seum;Chung, Yoon Kyu
    • Archives of Plastic Surgery
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    • 제39권4호
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    • pp.412-416
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    • 2012
  • Background Even though the quality of medical and surgical care has improved remarkably over time, iatrogenic injuries that require surgical treatment including injuries caused by cast and elastic bandage pressure, extravasation, and dopamine-induced ischemia still frequently occur. The goal of this study was to estimate the incidence and analyze the distribution of iatrogenic injuries referred to our department. Methods A retrospective clinical review was performed from April 2006 to November 2010. In total, 196 patients (116 females and 80 males) were referred to the plastic surgery department for the treatment of iatrogenic injuries. We analyzed the types and anatomic locations of iatrogenic complications, along with therapeutic results. Results An extravasation injury (65 cases, 37.4%) was the most common iatrogenic complication in our study sample, followed by splint-induced skin ulceration, dopamine-induced necrosis, prefabricated pneumatic walking brace-related wounds and elastic bandage-induced wounds. Among these, prefabricated pneumatic walking brace-related complication incidence increased the most during the 5-year study period. Conclusions The awareness of the very common iatrogenic complications and its causes may allow physicians to reduce their occurrence and allow for earlier detection and referral to a plastic surgeon. We believe this is the first study to analyze iatrogenic complications referred to a plastic surgery department in a hospital unit.

현황해독탕으로 호전된 급성편도선염 치험 4례 (Recovery of Symptoms and Signs in Four Cases of Acute Tonsillitis Treated with Hyunhwang-haedok-tang)

  • 김홍준;윤준철;김유경;강세영;심국진;백동기;원진희
    • 동의생리병리학회지
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    • 제18권1호
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    • pp.285-288
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    • 2004
  • This study was designed to report the clinical effects of Hyunhwang-haedok-tang on patients who have suffered from acute tonsillitis. Patients complained of fever, sore throat, swallowing difficulty, headache, cough. We give a diagnosis of acute tonsillitis. Therefore, we treated patients with oriental medicine, especially Hyunhwang-haedok-tang, and found that those symptoms and signs were improved by VAS, which is visual analogue scale. Through this study, Hyunhwang-haedok-tang on patients who have suffered from acute tonsillitis, proved to be effective.