• Biotechnology and Bioprocess Engineering:BBE
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• v.9 no.5
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• pp.414-418
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• 2004

A 'minimally complex problem set' for ab initio protein Structure prediction has been proposed. As well as consisting of non-redundant and crystallographically determined high-resolution protein structures, without disulphide bonds, modified residues, unusual connectivities and heteromolecules, it is more importantly a collection of protein structures. with a high probability of being the same in the crystal form as in solution. To our knowledge, this is the first attempt at this kind of dataset. Considering the lattice constraint in crystals, and the possible flexibility in solution of crystallographically determined protein structures, our dataset is thought to be the safest starting points for an ab initio protein structure prediction study.

• Proceedings of the Korean Biophysical Society Conference
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• 1996.07a
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• pp.29-29
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• 1996

The structure of an antimicrobial peptide buforin II has been studied by $^1$H NMR and CD spectroscopy. Buforin II is flexible and random structure in H$_2$O but the parts of buforin II become helical structure in trifluoroethanol (TFE)/H$_2$O (1:1, v/v) solution. From the restrained molecular dynamics calculation using NMR data, we obtained the possible conformation of buforin II in TFE/H$_2$O solution. (omitted)

• Journal of Electrochemical Science and Technology
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• v.2 no.2
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• pp.124-129
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• 2011

A simple process of fabricating micropillar structure and its influence upon enhancing electrochemical biosensor response were studied in this work. Conducting polymer PEDOT was used as a base material in formulating a composite with PVA. Micro porous PC membrane filter was used as a template for the micropillar of the composite on ITO electrode. This structure could provide plenty of encapsulating space for enzyme species. After dosing enzyme solution into this space, Nafion film tent was cast over the pillar structure to complete the micropillar cavity structure. In this way, the encapsulation of enzyme could be accomplished without any chemical modification. The amount of enzyme species was easily controllable by varying the concentration of the dosing solution. The more amount of enzyme is stored in the sensor, the higher the electrochemical response is produced. One more reason for the sensitivity improvement comes from the large surface area of the micropillar structure. Application of 0.7 V produced the best current response under the condition of pH 7.4. This biosensor showed linear response to the glucose in 0.1~1 mM range with the average sensitivity of $14.06{\mu}A/mMcm^2$. Detection limit was 0.01 mM based on S/N = 3.

• Membrane Journal
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• v.26 no.3
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• pp.187-196
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• 2016

Pressure-assisted forward osmosis (PAFO) process has recently been under spotlight for its potential to improve forward osmosis (FO) process performance by applying low hydraulic pressure on the feed side. Structure parameter, one of the governing factors in estimating water flux and solute flux across FO membranes in the solution-diffusion model (S-D model), determines solute resistivity in FO and PAFO processes. This study aims to estimate the trend of structure parameter change with respect to varying additional hydraulic pressure condition in PAFO.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.5
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• pp.695-702
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• 2002

Nonlinear dynamics of striped diffusion flames, by the diffusional-thermal instability with Lewis numbers sufficiently less than unity, is numerically investigated by examining various two-dimensional flame-structure solutions. The Lewis numbers for fuel and oxidizer are assumed to be identical and an overall single-step Arrhenius-type chemical reaction rate is employed in the model. Particular attention is focused on identifying the flame-stripe solution branches corresponding to each distinct stripe pattern and hysteresis encountered during the transition. At a Damkohler number slightly greater than the extinction Damkohler number, eight-stripe solution first emerges from one dimensional solution. The eight-stripe solution survives Damkohler numbers much smaller than the extinction Damkohler number until the transition to four-stripe solution occurs at the first forward transition Damkohler number. At the second forward transition Damkohler number, somewhat smaller than the first transition Damkohler number, the transition to two-stripe solution occurs. However, anu further transition from two-stripe solution to one-stripe solution is not always possible even if one-stripe solution can be independently accessed for particular initial conditions. The Damkohler number ranges for two-stripe and one-stripe solutions are found to be virtually identical because each stripe is an independent structure if distance between stripes is sufficiently large. By increasing the Damkohler number, the backward transition can be observed. In comparison with the forward transition Damkohler numbers, the corresponding backward transition Damkohler numbers are always much greater, thereby indicating significant hysteresis between the stripe patterns of strained diffusion flames.

• Journal of Sensor Science and Technology
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• v.24 no.2
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• pp.113-118
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• 2015

Intravenous (IV) infusion set is one of the most common treatment methods applied to hospitalized patients. However, it is necessary to check the injection of IV solution in order to prevent patients from any possible medical injuries. In this paper, using the optical sensors to detect exhaustion of IV solution was proposed. The optical sensor is coplanar structure composed of LED and photodiode which is installed according to focal distance of the lens. These two elements detect exhaustion of IV solution at the desired point conveniently. Through the results of experiments using various wavelength of LED (R.G.B), the blue LED was selected to the optimum light source. The suggested optical sensor can detect exhaustion of IV solution by the differences in the amount of light which is caused by properties such as total reflection, refractive index and scattering. From the implementation, the detector is applicable to both containers of IV solution, glass bottle and plastic pack. And also the result shows apparent differences according to existence of IV solution even if the IV solution color and illumination were changed.

• Journal of the Korean Ceramic Society
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• v.50 no.2
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• pp.127-133
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• 2013

Porcelain with high thermal shock resistance was successfully fabricated by a lithium solution infiltration method with a lithium hydroxide solution. Lithium hydroxide solutions having various lithium concentrations were infiltrated into pre-sintered porcelain bodies. The porcelain sample infiltrated by the 9 wt% lithium solution and heat treated at $1250^{\circ}C$ for 1 h showed a low thermal expansion coefficient of $1.0{\times}10^{-6}/^{\circ}C$ with excellent thermal shock resistance. The highly thermally resistant porcelain had a well-developed ${\beta}$-spodumene phase with the general phases observed in porcelain. Furthermore, the porcelain showed a denser structure of $2.41g/cm^3$ sintering density and excellent whiteness in comparison with commercial thermally resistible porcelains. The lithium hydroxide in the samples readily reacted with moisture, and liquid phase reactants were formed during the fabrication process. In the case of an excess amount of lithium in the sample body, the lithium reactants were forced to the surface and re-crystallized at the surface, leaving large pores beneath the surface. These phenomena resulted in an irregular structure in the surface area and led to cracking in samples subjected to a thermal shock test.

• The Journal of the Korea Contents Association
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• v.5 no.6
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• pp.360-367
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• 2005

Corporation's computerization developed by diffusion of internet, and dysfunction of Information is increasing greatly with virus, computing network infringement. Therefore, the today, corporation security is more and more emphasized. Security solution by that importance of security rises so is developing together Security solution is developing to ESM system in existing single system and important thing is function of each security solution and optimizing design of policy. Existent security policy taking a serious view security from external invasion but security of interior the importance rise the today. Accordingly, must construct ESM system of new structure for this. This paper proposes and embodied integration security administration system that solidify interior security utilizing IDS. Experiment external IP and ID access and analyzed the result.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.06a
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• pp.140-140
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• 2009

The Metal-ferroelectric-semiconductor (MFS) structure has superior advantages such as high density integration and non-destructive read-out operation. However, to obtain the desired electrical characteristics of an MFS structure is difficult because of interfacial reactions between ferroelectric thin film and Si substrate. As an alternative solution, the MFS structure with buffer insulating layer, i.e. metal-ferroelectric-insulator-semiconductor (MFIS), has been proposed to improve the interfacial properties. Insulators investigated as a buffer insulator in a MFIS structure, include $Ta_2O_5$, $HfO_2$, and $ZrO_2$ which are mainly high-k dielectrics. In this study, we prepared the Dy-doped $La_2O_3$ solution buffer layer as an insulator. To form a Dy-doped $La_2O_3$ buffer layer, the solution was spin-coated on p-type Si(100) wafer. The coated Dy-doped $La_2O_3$ films were annealed at various temperatures by rapid thermal annealing (RTA). To evaluate electrical properties, Au electrodes were thermally evaporated onto the surface of the samples. Finally, we observed the surface morphology and crystallization quality of the Dy-doped $La_2O_3$ on Si using atomic force microscopy (AFM) and x-ray diffractometer (XRD), respectively. To evaluate electrical properties, the capacitance-voltage (C-V) and current density-voltage (J-V) characteristics of Au/Dy-doped La2O3/Si structure were measured.

• Journal of Chest Surgery
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• v.33 no.5
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• pp.377-384
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• 2000

Background: Numerous studies of safe, long term preservation for lung transplantation have been performed using ex vivo models or in vivo single lung transplantation models. However, a safe preservation time which is applicable for clinical use is difficult to determine. We prepared LPDG solution for lung preservation study. In this study we examined the efficacy of LPDG(low potassium dextran glucose) solution in 24-hour lung preservation by using a sequential bilateral canine lung allotransplant model. Material and Method: Seven bilateral lung transplant procedures were performed using weight-matched pairs(24 to 25kg) of adult mongrel dogs. The donor lungs were flushed with LPDG solution and maintained hyperinflated with 100% oxygen at 1$0^{\circ}C$ for a planned ischemic time of 24 hours for the lung implanted first. After sequential bilateral lung transplantation, dogs were maintained on ventilators for 3 hours: arterial resistance were determined if the recipients hourly after bilateral reperfusion and compared with pretransplant-recipient values, which were used as controls. After 2hours of reperfusion, the chest X-ray, computed tomogram and lung perfusion scan were performed for assessmint of early graft lung function. Pathological examinations for ultrastructural findings of alveolar structure and endothelial structure of pulmonary artery were performed. Result: Five of seven experiments successfully finished the whole assessments after bilateral reperfusion for three hours. Arterial oxygen tension in the recipients was markedly decrased in immediate reperfusion period but gradually recovered after reperfusion for three hours. The pulmonary artery and pulmonary vascular resistance showed singificant elevation(p<0.05 versus control values) but also recovered after reperfusion for three hours(p<0.05 versus immediate period value). The ultrastructural findings of alveolar structure and endothelial structure of pulmonary artery showed reversible mild injury in 24 hours of lung perservation and reperfusion. Conclusion : This study suggests that LPDG solution provides excellent preservation in a canine model in which the dog is completely dependent on the function of the transplanted lung.