Structure of an Antimicrobial Peptide Buforin II

  • Yi, Gwan-Su (Magnetic Resonace Group, Korea Basic Science Institute) ;
  • Park, Chan-Bae (Department of Biological Sciences, Korea Advanced Institute of Science and Technolog) ;
  • Kim, Sun-Chang (Department of Biological Sciences, Korea Advanced Institute of Science and Technolog) ;
  • Chaejoon Cheong (Magnetic Resonance Group, Korea Basic Science Institute)
  • 발행 : 1996.07.01

초록

The structure of an antimicrobial peptide buforin II has been studied by $^1$H NMR and CD spectroscopy. Buforin II is flexible and random structure in H$_2$O but the parts of buforin II become helical structure in trifluoroethanol (TFE)/H$_2$O (1:1, v/v) solution. From the restrained molecular dynamics calculation using NMR data, we obtained the possible conformation of buforin II in TFE/H$_2$O solution. (omitted)

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