• Proceedings of the Korea Contents Association Conference
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• 2006.05a
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• pp.503-506
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• 2006

In this paper, we suggest the Agent System for management and service of science and technology information that performs the collection, analyzing, processing and managing the information. Generally, any system can process the collection and service the information as usual method, but that mean can't be clear because of the data process method on different systems of hardware and software. So, it's very important point that the design and development of S&T information flow framework that can accept the various data, and we expect that the agent system adapted in framework guarantee the reduction of man power and process time and the enlarged system. Agent System consists of five multi agents, Resource Format Register Agent, Data Collector Agent, Data Analyzer Agent, Data Processor Agent and MetaDB Creator Agent. We describe the main roles and elements of agent systems.

• Journal of KIISE:Software and Applications
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• v.36 no.3
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• pp.200-207
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• 2009

U-Healthcare is more efficient as a solving method for health problems rather than visiting the hospital. Recently, systems have been studied to offer appropriate service to user, which gather and analyze biological signals of a user and context information around the user from a variety of sensors. The existing systems for U-Healthcare are based on domain specific service so it is difficult to expand and link to other systems. Also, they lack services focusing on the specific quality of the user, because they offer a general service which targets a lot of users. To address this problem, we expand an extensibility of system using the context-awareness agent based on multi-agents. Also, we provide the suitable services which match with the context information of user to each user using the modeling toolkit JaUCE based on GUI. We design and implement U-Silvercare service to demonstrate the effectiveness of the proposed context-awareness agent and modeling toolkit.

• Journal of Advanced Marine Engineering and Technology
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• v.40 no.5
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• pp.418-428
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• 2016

In this study, a Vessel Shore Report Management System (VSRMS) is developed for the International Maritime Organization (IMO), Maritime Service Portfolio (MSP) Number 8, which comprises vessel shore reporting. Several documents have to be completed before the arrival/departure of a vessel at a port, as each national port has its own reporting format and data. The present vessel reporting system is inefficient, time-consuming, and involves excessive paperwork, which results in duplications and errors. To solve this problem, in this study, the vessel reporting formats and data contents of various national ports are investigated, as at present, the reporting documents required by the current IMO standard includes insufficient information which is requested by national ports. Initially, the vessel reporting information of various national ports are collected and analyzed. Subsequently, a database structure for managing vessel reporting data for ports worldwide is devised. To make the transfer of data and the exchange of information of vessel reports much more reliable, efficient, and paper-free, VSRMS, which is a software application for the simplification and facilitation of vessel report formalities, is developed. This application is developed using the latest Microsoft C#.Net Programming Language in the Microsoft Visual Studio framework 4.5. It provides a user interface and a backend MySQL server used for database management. SAP Crystal Reports 2013 is used for designing and generating vessel reports in the original report formats. The VSRMS can facilitate vessel reporting and improve data accuracy through the reduction of input data, efficient data exchange, and reduction of the cost of communication. Adoption of the VSRMS will allow the vessel shore reporting system to be automated, resulting in enhanced work efficiency for shipping companies. Based on this information system and architecture, the consensus of various international organizations, such as the IMO, the International Association of Marine Aids to Navigation and Lighthouse Authorities (IALA), the Federation of National Associations of Ship Brokers and Agents (FONASBA), and the Baltic and International Maritime Council (BIMCO), is required so that vessel reporting is standardized internationally.

• Smart Structures and Systems
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• v.26 no.2
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• pp.147-156
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• 2020

This numerical study demonstrates the porosity conditions and the intensity of the interactions with the aggressive agents. It is established that the density as well as the elastic modulus are correlated to ultrasonic velocity The following investigation assessed the effects of cement grade and porosity on tensile strength, flexural and compressive of Ultra High Performance Concrete (UHPC) as a numerical model in PLAXIS 2d Software. Initially, the existing strength-porosity equations were investigated. Furthermore, comparisons of the proposed equations with the existing models suggested the high accuracy of the proposed equations in predicting, cement grade concrete strength. The outcome obtained showed a ductile failure when un-corroded reinforced concrete demonstrates several bending-induced cracks transfer to the steel reinforcement. Moreover, the outcome also showed a brittle failure when wider but fewer transverse cracks occurred under bending loads. Sustained loading as well as initial pre-cracked condition during the corrosion development have shown to have significant impact on the corrosion behavior of concrete properties. Moreover, greater porosity was generally associated with lower compressive, flexural, and tensile strength. Higher cement grade, on the other hand, resulted in lower reduction in concrete strength. This finding highlighted the critical role of cement strength grade in determining the mechanical properties of concrete.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5037-5042
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• 2012

Background: Tobacco contains agents which generate various potent DNA adducts that can cause gene mutations. Production of DNA adducts may be neutralized by glutathione S transferase (GST) along with other phase I and phase II enzyme systems. The existence of null type of GST among the population increases the susceptibility to various disorders and diseases. The present study focuses on the impact of high tobacco usage and possible null type mutation in GST loci. Methods: Genotypes of GST were detected by multiplex polymerase chain reaction in unrelated 504 volunteers of high tobacco using natives of Gujarat. Allelic frequencies were calculated using Statistical Package for Social Studies-16 software. Hardy Weinberg Equilibrium (HWE) was calculated using Chi square test. Two sided Fisher's significance test was used to compare allelic frequencies of different populations. Results: The frequency of homozygous null genotype of GSTM1 and GSTT1 were 20% (95% CI 16.7-23.9) and 35.5% (95% CI 31.4-39.9) respectively. The GSTM1 and GSTT1 null allele frequency distribution in the Gujarat population was significantly deviating from HWE. GSTT1 null frequency of Gujaratians was significantly higher and different to all reported low tobacco using Indian ethnics, while GSTM1 was not differing significantly. Conclusion: Tobacco usage significantly influences the rate of mutation and frequency of GSTT1 and M1 null types among the habituates. The rate of mutation in GSTT1 loci was an undeviating response to the dose of tobacco usage among the population. This mutational impact of tobacco on GSTT1 postulates the possible gene - environment interaction and selection of null genotype among the subjects to prone them under susceptible status for various cancers and even worst to cure the population with GSTT1 dependent drugs.

• Journal of Korea Multimedia Society
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• v.6 no.6
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• pp.1111-1119
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• 2003

The research of science and engineering needs the latest information from internet resources. But it is a complex and repeated procedure to search and filter web documents from the huge Internet resources. In this paper, we propose the PREA system, which can organize the research paper databases and search World Wide Web documents that the user is interested in. It observes the usage of the local Paper databases and presented web documents and then constructs a profile intelligently. However, to make a profile, we used the modified spreading activation network(MSAN) so that the PREA can search and filter web documents by semantic meaning of user's interest in realtime. The system constructed in multi-agents manner that can cooperate together effectively. The results show the effectiveness of our system to search web documents compared with a commercial search engine.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10847-10853
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• 2015

Background: Lapatinib, a dual tyrosine kinase inhibitor that interrupts the epidermal growth factor receptor (EGFR) and HER2/neu pathways, has been indicated to have significant efficacy in treating HER2-positive breast cancer. However, acquired drug resistance has become a very serious clinical problem that hampers the use of this agent. In this study, we aimed to screen small molecule drugs that might reverse lapatinib-resistance of breast cancer by exploring differentially expressed genes (DEGs) via a bioinformatics method. Materials and Methods: We downloaded the gene expression profile of BT474-J4 (acquired lapatinib-resistant) and BT474 (lapatinib-sensitive) cell lines from the Gene Expression Omnibus (GEO) database and selected differentially expressed genes (DEGs) using dChip software. Then, gene ontology and pathway enrichment analyses were performed with the DAVID database. Finally, a connectivity map was utilized for predicting potential chemicals that reverse lapatinib-resistance. Results: A total of 1, 657 DEGs were obtained. These DEGs were enriched in 10 pathways, including cell cycling, regulation of actin cytoskeleton and focal adhesion associate examples. In addition, several small molecules were screened as the potential therapeutic agents capable of overcoming lapatinib-resistance. Conclusions: The results of our analysis provided a novel strategy for investigating the mechanism of lapatinib-resistance and identifying potential small molecule drugs for breast cancer treatment.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.1
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• pp.137-149
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• 2004

A new software paradigm is required on the development of network and various service requirements. With this, many studies on a mobile agent have been made. For the execution of the mobile agent, migration is the most important factor that influences the performance of the mobile agent. In this paper we propose the method that leads to high migration efficiency in order to improve the performance. The features of our migration technique are as follows. First, the migration technique creates the dynamic itinerary that appropriately copes with the network conditions and the platform changes to improve the agent execution efficiency. Second, it perfecters an executed code to reduce the amount of the mobile data and reduces the execution time by instantiating the agent in advance. Third, it improves the execution efficiency by using the checkpoint-based recovery method that does not execute the agent again and recovers the process states even though the errors take place. Though the simulation we compare the proposed method with the existing methods. The simulation result shows that the proposed method outperform the existing methods in terms of migration.

• KIPS Transactions on Software and Data Engineering
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• v.3 no.6
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• pp.231-236
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• 2014

The transit time of contrast agents and the parameters of time-intensity curves in ultrasonography are important factors to diagnose various diseases of a digestive organ. We have implemented an automatic parametric imaging method to overcome the difficulty of the diagnosis by naked eyes. However, the micro-bubble noise and the respiratory motions may degrade the reliability of the parameter images. In this paper, we introduce an optimization technique based on MRF(Markov Random Field) model to enhance the quality of the parameter images, and present an image tracking algorithm to compensate the image distortion by respiratory motions. A method to extract the respiration periods from the ultrasound image sequence has been developed. We have implemented the ROI(Region of Interest) tracking algorithm using the dynamic weights and a momentum factor based on these periods. An energy function is defined for the Gibbs sampler of the image enhancement method. Through the experiments using the data to diagnose liver lesions, we have shown that the proposed method improves the quality of the parametric images.

• Archives of design research
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• v.9
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• pp.801-810
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• 1994

Design Problems are often both multidimensional and highly interactive. Very rarely does any part of a designed thing serve only one purpose. The activity of designing is thus a goal-directed activity and normally a goal-directed problem-solving activity. This means, problem solving is finding a way to get from some initial situation to a desired goal. Designers are transforming agents within a society whose goals are to improve the human condition through physical metamorphosis. Many theorist have agreed that designing involves problem solving or decision making. Accordingly evaluation plays an essential role in design activity. The evaluation factors include all attributes that have levels specified by quantitative and qualitative objectives Alternatives in multi-objective decision prOblems generally possess numerous attributes by which they can be described and compared. The evaluation factors include all attributes that have levels specified by quantitative and qualitative objectives. However since qualitative factors are difficult to quantify as numeral estimates, these factors have tended to be ignored without regard for their importance to human content. We adapted the Accumulative Evaluation Model as an evaluation algorithm for IDES. Industrial Design Evaluation System (IDES) consists of 3 major modules ( 1 Design Element, 2.Matrix, 3.Evaluation). It is intended to be an aid for design evaluation. The luther thinks IDES is a new design evaluation approach which could provide effective rating of design values to make value judgements. It is an attempt to provide industrial designers with access to design evaluation. The author's aim is to produce an Object-Oriented Evaluation System which can guide the designers and decision makers under complex design projects. It uses\ulcorner an Object-Oriented Programming for this prototype, Because of managing complexity (Flexibility and Reusability) and improving productivity(Extensibility & Maintainability and Programming by User) in software development process. The author has chose the C++ because it is a hybrid, rather than pure Object-Oriented Language.