• 한국응용과학기술학회지
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• 제25권1호
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• pp.83-90
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• 2008

The core-shell latex particles were prepared by sequential emulsion polymerization using alkyl methacrylate as a shell monomer and potassium persulfate (KPS) as an initiator. We study the effects of core-shell structure of calcium carbonate/alkyl methacrlyate in the presence of an anionic surfactant sodium lauryl sulfate (SLS) and polyoxyethylene alkyl ether sulfate (EU-S133D)). The structure of core-shell polymer were investigated by measuring to the thermal decomposition of polymer composite using thermogravimetric analyzer and morphology of latex by transmission electron microscope (TEM).

• 한국산학기술학회논문지
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• 제11권8호
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• pp.2935-2941
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• 2010

본 논문은 SLS의 함유정도를 다르게 한 A(0%), B(1.1%), C(2.2%)의 세가지 실험세치제를 제작하여 구취변화를 실험하였다. 대상은 전신질환이 없는 20대 성인 150명이었으며 50명씩 세 그룹(A, B, C )으로 나누어 진행되었다. SLS함량에 따른 세치제의 4주간사용 후 3집단의 구취변화를 황화물가스와 암모니아 양의 변화로 측정한 결과 3집단 모두 집단내의 변화는 있는 것으로 나타났지만 SLS함량에 따른 상관관계를 본 결과에서는 구강황(r=0.412)과 호기황(r=0.285)에서만 상관관계가 있는 것으로 나타났다. 이는 잇솔질의 개선으로 인한 변화라고 볼 수 있으며 SLS의 함량이 높을수록 타액분비율을 저하시켜, 구강건조를 유발하므로 구강 황화합물과 호기 황화합물의 수치가 높게 나온 것으로 생각된다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 춘계학술대회
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• pp.288-288
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• 1996

The microcapsules containing ethanol in a water-soluble polymer shell could be formed by the spray-drying technique. A mixed solution of ethanol, water and a water-soluble polymer is spray-dried at the lowest possible temperature to obtain a powder product in which the water is substantially removed and the ethanol is encapsulated in water-soluble polymer shell because of the hydrophillic property of polymer and permeability difference between ethanol and water. In this study, the effect of sodium lauryl sulfate (SLS) on the ethanol content, ethanol encapsulation efficiency and yield were investigated to maximize the microencapsulation of ethanol.

• 열처리공학회지
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• 제37권1호
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• pp.16-22
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• 2024

The conventional degreasing process involves removing oil and contaminants at temperatures above 80℃, resulting in excessive energy consumption, increased process costs, and environmental issues. In this study, we aimed to find the optimal degreasing conditions for the pre-treatment process of electro-galvanizing cold-rolled steel sheets, conducted efficiently at room temperature without the need for a separate heating device. To achieve this, we developed a room temperature degreasing solution and a brush-type degreasing tool, aiming to reduce energy consumption and normalize the decrease in degreasing efficiency caused by temperature reduction. Alkaline degreasing solution were prepared using KOH, SiO₂, NaOH, Na₂CO₃, and Sodium Lauryl Sulfate, with KOH and NaOH as the main components. To enhance the degreasing performance at room temperature, we manufactured additives including sodium oleate, sodium stearate, sodium palmitate, sodium lauryl sulfate, ammonium lauryl sulfate, silicone emulsion, and EDTA-Na. Room temperature additives were added to the alkaline degreasing solution in quantities ranging from 0.1 to 20 wt.%, and the uniformity of degreasing and the adhesion of the galvanized layer were evaluated through Dyne Test, T-bending Test, OM, SEM, and EDS analyses. The results indicated that the optimal degreasing solution composition consisted of NaOH (30 g/L), Na₂CO₃ (30 g/L), SLS (6 g/L), and room temperature additives (≤1 wt%).

• Toxicological Research
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• 제19권2호
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• pp.133-139
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• 2003

Allergic contact dermatitis may be caused by a wide variety of chemicals. A murine local lymph node assay (LLNA) has been developed as an alternative to guinea pig models for assessing the contact sensitization potential of chemical. However, there is a need to develop a nonradioisotopic endpoint for the LLNA, because of the radioisotopic method's requiring the use of special facilities. In this study, we investigated the development of a nonradioisotopic endpoint for LLNA using ELISA (enzyme-linked immunosorbent assay). Female Balb/c mice were treated by the topical application on the dorsum of both ears with four different strong sensitizers, 2,4-dinitrochlorobenzene (DNCB), oxazolone (OXZ), toluene diisocyanate (TDI), and trimellitic anhydride (TMA), and a strong irritant, sodium lauryl sulfate (SLS), once daily for three consecutive days. The proliferation of cells in the auricular Iymph node was analyzed by means of the labelling index (Ll) of bromodeoxyuridine (BrdU) incorporation into cells. The weights of the Iymph nodes in the mice treated with allergens, DNCB, OXZ, TDl and TMA were increased compared to the vehicle control. The stimulation index (Sl) of mice treated with DNCB, OXZ, TDl, and TMA was over three-fold increase compared to the vehicle control. However, the S1 of mice exposed to SLS was not significantly increased compared to the vehicle control, while the lymph node weight of SLS was significantly increased. These results suggest that the LLNA modified endpoint using ELISA based on BrdU incorporation could provide a useful method of screening for irritants and allergens.

• 한국환경과학회지
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• 제5권3호
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• pp.369-376
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• 1996

The adsorption of the anionic surfactants, sodium lauryl sulfate (SLS) and sodium dodecylbenzene sulfonate (SDBS) anion surfactants form aqueous solutions with nonionic resins, Amberlite XAD-2, XAD-4 and XAD-7 at temperatures in 15~45$^{\circ}C$ range was studied. Several adsorption isotherm models were used to fit the experimental data, The best results were obtained with the Redlich-Peterson equation and the Freundlich model provided remarkably good fits. For a particular resin at a particular temperature, SDBS was more extensively adsorbed than SLS. The highest adsorption were obtained with XAD-4 resin and the specific surface area of the resins plays a major role in adsorption of the surfactants. Estimations of the isosteric heat of adsorption were indicative of an exothermic process, and their magnitudes manifested a physisorption process.

• 디지털융복합연구
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• 제17권3호
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• pp.305-312
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• 2019

본 논문은 치약의 성분이 구강 내 세포에 영향을 미치는 정도를 확인하기 위하여 세포활성도, 세포독성을 평가하고자 하였다. 일반치약 6종, 미백치약 3종, 천연치약 2종, 양성대조군으로 SLS(sodium lauryl sulfate)를 사용하였다. Immortalized human gingiva fibroblast cell 을 사용하여, 세포활성도 평가를 위하여 WST test, 세포 독성평가를 위해 Agar diffusion test를 시행하였다. 일반치약그룹, 미백치약그룹, 천연치약그룹 순으로 세포 생존률이 높게 나타났으며, Agar diffusion test는 일반치약그룹과 미백치약그룹은 높은 세포독성을 나타낸 반면 천연치약그룹은 낮은 독성을 나타냈다. 세포핵염색 결과 세포모양과 핵활성도 또한 천연치약이 가장 높은 활성도를 나타냈고, 미백치약, 일반치약 순으로 나타났다. 본 연구 결과, 치약의 사용목적에 따라 나누어지는 종류와 성분별 세포독성을 확인할 수 있었다. 소비자의 올바른 선택을 위해 치약의 자세한 성분표기가 필요할 것으로 사료된다.

• The Korean Journal of Physiology and Pharmacology
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• 제17권1호
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• pp.9-13
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• 2013

The aim of the present study was to examine the effect of micellar systems on the absorption of beta-lapachone (b-lap) through different intestinal segments using a single-pass rat intestinal perfusion technique. B-lap was solubilized in mixed micelles composed of phosphatidylcholine and sodium deoxycholate, and in sodium lauryl sulfate (SLS)-based conventional micelles. Both mixed micelles and SLS micelles improved the in situ permeability of b-lap in all intestinal segments tested although the mixed micellar formulation was more effective in increasing the intestinal absorption of b-lap. The permeability of b-lap was greatest in the large intestinal segments. Compared with SLS micelles, the effective permeability coefficient values measured with mixed micelles were 5- to 23-fold higher depending on the intestinal segment. Our data suggest that b-lap should be delivered to the large intestine using a mixed micellar system for improved absorption.

• 한국응용과학기술학회지
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• 제12권1호
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• pp.47-54
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• 1995

각종 세정제의 난용 및 과대 사용으로 인한 수질오염이 날로 심각해지고 있으며 이 때 수질오염의 원인은 주로 계면활성제에 의해 발생한다. 본 연구는 이미 다졸린으로부터 유도된 9종의 양쪽성계면활성제와 석유 화학물질로부터 제조하여 대량 사용하고 있는 sodium lauryl sulfate(SLS)에 대한 세정성을 비교하여 보다 우수한 계면활성제를 선정하고자 한다. 또한 세정성의 비교는 세정력의 측정과 세정에 관한 물리화학적 측면에서 그 원인을 규명하고자 한다. 1-(2-hydroxyethyl)-1-(3-sulfonatedropy)-2-undecyl-2-imidazolinum [IV]는 세정성 및 다른 기초적 물성이 우수하여 세정제에 응용할 경우 세정성이 우수한 계면활성제 일수록 오염 부착에 필요한 일이 적게 나타나 오염이 쉽게 제거될 수 있음을 증명하였으며 그로 인한 공업적 응용성에 기대가 크다.

• Biomolecules & Therapeutics
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• 제23권1호
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• pp.90-97
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• 2015

Water chestnut (Trapa japonica Flerov.) is an annual aquatic plant. In the present study, we showed that the treatment of water chestnut extracted with boiling water resulted in a significant increase 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity and decrease the intracellular $H_2O_2$-induced accumulation of reactive oxygen species. In addition, water chestnut extract (WCE) inhibited lipopolysaccharide (LPS)-induced nitric oxide production and suppressed mRNA and protein expression of the inducible nitric oxide synthase gene. The cytokine array results showed that WCE inhibited inflammatory cytokine secretion. Also, WCE reduced tumor necrosis factor-${\alpha}$- and interleukin-6-induced nuclear factor-${\kappa}B$ activity. Furthermore, during sodium lauryl sulfate (SLS)-induced irritation of human skin, WCE reduced SLS-induced skin erythema and improved barrier regeneration. These results indicate that WCE may be a promising topical anti-inflammatory agent.