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http://dx.doi.org/10.14400/JDC.2019.17.3.305

A convergence study of cytotoxicity evaluation of adult dentifrices  

Choi, Yu-Ri (Department of Dental hygiene, Hallym polytechnic University)
Shim, Youn-Soo (Department of Dental hygiene, Sunmoon University)
Jang, Sun-Ok (Department of Dental hygiene, Hallym polytechnic University)
Publication Information
Journal of Digital Convergence / v.17, no.3, 2019 , pp. 305-312 More about this Journal
Abstract
This study was conducted to effect the cell activity and cytotoxicity of dentifrice. For the study, 6 kinds of general dentifrice, 3 kind of whitening dentifrice, 2 kinds of natural dentifrice and SLS(sodium lauryl sulfate) of positive control group. Immortalized human gingiva fibroblast cell was used for the study, WST test for cell activity and Agar diffusion test for cytotoxicity. Agar diffusion test showed high cytotoxicity in general dentifrice test group and whitening dentifrice test group, but low cytotoxicity in natural dentifrice test group. As a result of cell nucleus staining, cell shape and nuclear activity showed that the highest activity in natural dentifrice group, followed by whitening dentifrice group and general dentifrice group. As a result of this study, the cytotoxicity of different ingredient and according to the use to dentifrice. As a result of this study, we confirm cytotoxicity of kind and components according to the purpose of using dentifrice. Therefore, it is necessary to indicate the detailed ingredients of dentifrice for the smart choice of consumers.
Keywords
Convergence; Dentifrice; Cell Viability; Cytotoxicity; Surfactants;
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