• Title/Summary/Keyword: Sodium Bicarbonate

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Half-degumming Behaviors of Raw Silk Yarns Degummed with Soap and Alkalis (비누와 알칼리에 의한 실크 생사의 반숙정련 거동)

  • Park, Geon-Yong
    • Textile Coloration and Finishing
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    • v.22 no.4
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    • pp.349-355
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    • 2010
  • To investigate the half-degumming of raw silk, the degumming was carried out with soap or sodium carbonate or sodium bicarbonate and some mixed agents at $80^{\circ}C$ for 15 and 30 minutes. With soap of 20~25%o.w.f. degumming losses were about 7~12%. Degumming losses with sodium carbonate of 2~5%o.w.f. were about 6~15%. And about 6~12% wright losses were observed in the degumming with sodium bicarbonate of 20~30%o.w.f. In the degumming with the mixed degumming agents of soap and sodium carbonate, degumming losses were 9~15% with 5%o.w.f. soap and 2~5%o.w.f. sodium carbonate. Sodium carbonate was more effective on the removal of sericin from raw silk than soap. During drying generally half degummed silk yarns stuck together to result in harsh and hard lumps by the adhesion and solidification of the residue sericin of partially degummed silk. Sodium hydrosulfite in degumming agent effectively protected the adhesion of half degummed silk yarns.

A CLINICAL STUDY OF ANESTHETIC EFFICACY OF ALKALINIZING LIDOCAINE IN INFERIOR ALVEOLAR NERVE BLOCKS (하치조신경 전달 마취 시 알칼리화 된 리도카인의 마취 효능에 관한 임상적 연구)

  • Kim, Tae-Hwan;Kim, Kyung-Wook;Kim, Chul-Hwan
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.27 no.3
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    • pp.276-282
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    • 2005
  • Inferior alveolar nerve block using lidocaine is the most frequent local anesthetic method in the dental treatment, but clinically it is not always successful. The 2% lidocaine cartridge has been used commonly in dental anesthesia. It contains vasoconstrictor and antioxidant, which presents low pH which provides chemical stability and longer shelf life. But alkalinized local anesthetics has less tissue trauma, easier dissociation of the non-ionized base which penetrates nerve sheath, rapid onset and more intensity. In this study, in inferior alveolar nerve block, alkalinized lidocaine using sodium bicarbonate (experimental group) is compared with plain lidocaine (control group) about injection pain, anesthetic onset, duration and postinjection discomfort. In inferior alveolar nerve block, alkalinized lidocaine using sodium bicarbonate showed lower injection pain. There was significant difference statistically from plain lidocaine(p=0.019). Comparing with plain lidocaine, alkalinized lidocaine produced more rapid onset (lip & pulp anesthetic onset), there was no significant difference(p>0.05). but there was boundary significance (0.050.05). These results suggest that addition of sodium bicarbonate to 2% lidocaine(1:100,000 epinephrine) for inferior alveolar nerve block is more effective for reduction of injection pain and onset time.

Dissolution Test to Optimize Liquid Formulations for Enteric Coated Tablets and Capsules Containing Enteric Coated Granules of Omeprazole (장용정 Omeprazole정제와 캅셀제의 액제화 투여 방법의 용출시험)

  • Jang, Hyejung;Lee, Sukhyang
    • Korean Journal of Clinical Pharmacy
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    • v.11 no.1
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    • pp.13-18
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    • 2001
  • Omeprazole is usually administered as encapsulated enteric-coated granules and enteric-coated tablets because of its acid-labile nature. For children and patients who can not swallow, it can be mixed with water or other liquid after a capsule is opened or a tablet is crushed. This study was performed to compare omeprazole liquid formulations of tablet and capsule Omeprazole 20 mg capsule containing enteric coated granules was opened and 20 mg entric-coated tablet was ground to be mixed with sodium bicarbonate solution, orange juice or water. Each liquid formulation was poured into dissolution tester, mixed with first solution (artificial gastric juice; pH 1.2) for two hours, then with second solution (artifical enteric juice; pH 6.8) for thirty minutes. pH was measured periodically for two and half hours. Samples were drawn periodically, mixed with lansoprazole as an internal standard, and injected to HPLC. As results, pH of sodium bicarbonate solution of omeprazole was significantly higher than that of orange juice or water in first solution (6.2-7.4 vs. 1.2, p<0.005). At 150 min, concentrations of omeprazole in three diluents with granules and in sodium bicarbonate solution of tablet powder sustained significantly higher than in other solution of tablet powder (p<0.001). In conclusion, enteric-coated granules from capsule with three diluents and powder from tablet in sodium bicarbonate solution was stable during dissolution test, which would be appropriate and recommended for patient who can not swallow solid preparations.

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Revision of the Analysis of Makgeolli for Ochratoxin A (막걸리 중 ochratoxin A 분석의 개선)

  • Park, Je-Won
    • Korean Journal of Food Science and Technology
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    • v.38 no.1
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    • pp.140-142
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    • 2006
  • Because ochratoxin A recovery level of Makgeolli is lower (<50%) than those of other commodities such as rice, barley, and beer, Makgeolli was evaluated to improve the recovery and enable routine analysis. Use of 3% sodium bicarbonate instead of phosphate-buffered saline as homogenizing solution provided good recovery of ochratoxin A (>80%) spiked in Makgeolli at level of 1 ppb. To determine if this analytical method is reliable for ochratoxin A detection in Makgeolli, survey was conducted for ochratoxin A in 30 sterile Makgeolli samples retailed in Korea. Only two wheat-based Makgeolli samples contained detectable level of ochratoxin A (0.8 and 2.1 ppb) as confirmed by HPLC- electrospray ionization- mass spectrometry. Extraction of sample with 3% sodium bicarbonate for 3 min, followed by cleanup of extracts with immunoaffinity columns, and HPLC with fluorescence detection provided dependable detection of ochratoxin A in Makgeolli samples.

Chemical Characterization of Neutral Extracts Prepared by Treating Pinus radiata Bark with Sodium Bicarbonate

  • MUN, Ji Sun;KIM, Hwan Chul;MUN, Sung Phil
    • Journal of the Korean Wood Science and Technology
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    • v.48 no.6
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    • pp.878-887
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    • 2020
  • A neutral extract (NE), that is soluble in cold water and has excellent antioxidant activity, from Pinus radiata pine bark was prepared by sodium bicarbonate treatment, and its chemical characteristics were investigated. NE was prepared by treating P. radiata bark with 0.8% NaHCO3 aqueous solution with a 5 : 1 liquor-to-bark ratio at boiling temperature for 1 h, resulting in 44% yield and final pH of 6.66. The yield of NE was 11% higher than that of the hot water extract (HWE) due to the increase in the solubility of polyphenols, the main component in the bark, by NaHCO3 treatment. NE was characterized through FT-IR, NMR, and MALDI TOF MS analyses. The results indicated that NE is mostly composed of proanthocyanidins (PAs) consisting of procyanidin (PC) units. The acetylated neutral extract (Ac-NE) had weight average molecular weight (${\bar{M}}w$) of 5,300 Da. The Ac-NE had wide molecular weight distribution and its polydispersity (${\bar{M}}w/{\bar{M}}n$) was 6 times higher than that of pure PA. The antioxidant activity of NE was determined by 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and showed that NE had comparable antioxidant activity with pure PA.

Randomized Controlled Trial for Preventing Stomatitis and Discomfort among Acute Leukemic Patients (급성백혈병 환자를 대상으로 구강함수제별 구내염 및 구강안위감에 대한 무작위대조시험연구)

  • Song, Chi-Eun;So, Hyang-Sook;Ju, Deok;Kim, Eun-Jeong
    • Asian Oncology Nursing
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    • v.11 no.1
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    • pp.33-40
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    • 2011
  • Purpose: This study compared the effect of two oral care agents on preventing stomatitis and discomfort for acute leukemic patients. Methods: A total of forty patients was enrolled and randomly assigned to sodium bicarbonate or chlorhexidine group. WHO oral toxicity scale was used for measuring stomatitis and Beck's subjective oral discomfort scale for evaluating oral comfort. Data was collected from August 2009 to February 2010. The data was analyzed using Chi-square test, Fisher's exact test, and Mann-Whitney test. Results: Data analyzed was thirty five one. The incidence of stomatitis was 47.4%, 68.8% in sodium bicarbonate and chlohexidine group respectively. The onset of stomatitis was about the 10th and 9th day after chemotherapy initiation, and the duration was 8.0 and 8.67 day respectively. The severity of stomatitis was highest on the 21st day after chemotherapy initiation. There were no statistical differences in the status of stomatitis and the levels of oral comfort during treatment periods. Conclusion: Nurses should routinely assess oral cavity and encourage patients to do oral care actively from second to third week after chemotherapy initiation. Also sodium bicarbonate agent can be recommended to for preventing stomatitis.

Anaesthetic Effect of Lidocaine Hydrochloride-Sodium Bicarbonate on the Winter Flounder, Pleuronectes americanus (Winter flounder, Pleuronectes americanus에 대한 염산리도카인-중탄산나트륨의 마취효과)

  • Park, In-Seok;Hur, Jun-Wook;Song, Young-Chae;Im Jae-Hyun;Johnson Stewart C.
    • Ocean and Polar Research
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    • v.26 no.3
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    • pp.475-480
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    • 2004
  • Recently, less toxic and more effective anaesthetics are essential for marine fishes. Lidocaine belongs to a group of anaesthetics which are used as local anaesthetic in human medicine. This chemical was tested fer winter flounder, Pleunnectes americanus. Anaesthetic effect of lidocaine hydrochloride-sodium bicarbonate mixture (lidocaine $HCl/NaHCO_3$) was tested for the winter flounder at five different temperature regimes: $3^{\circ}C,\;7^{\circ}C,\;11^{\circ}C,\;15^{\circ}C\;and\;19^{\circ}C$ Anaesthetic dose and temperature-dependent relationship in exposure and recovery time were observed for the winter flounder of $17.2{\pm}0.1cm$ mean total length. Based on the results, anaesthetic lidocaine $HCl/NaHCO_3$ showed rapid exposure time and rapid recovery time for winter flounder. The results indicate that lidocaine $HCl/NaHCO_3$ can be used as suitable anaesthetic for this species.

Geochemical evaluation of groundwater quality of Peshawar Basin, Pakistan

  • Akhter, Gulraiz;Mand, Bilal A.;Shah, Munir H.
    • Advances in environmental research
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    • v.10 no.1
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    • pp.43-57
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    • 2021
  • Evaluation of groundwater quality is vital due to its diverse use for several purposes. In the present study, groundwater quality and suitability from the Peshawar basin, Pakistan, were evaluated for drinking and irrigation purposes. The water samples were analysed for major cations (Ca, Mg, Na and K) and anions (chloride, bicarbonate and sulphate) along with other physicochemical parameters (pH, electrical conductivity, total dissolved solids, and total hardness). About 95% of the water samples were found to be within the WHO, US-EPA and Pak-EPA permissible levels for drinking purposes. Seventy percent (70%) of the water samples belonged to the hard water category. Irrigation water quality parameters, such as, chloride, residual sodium bicarbonate, sodium adsorption ratio, percent sodium, magnesium adsorption ratio, Kelly's ration and permeability index were evaluated which demonstrated that the groundwater was highly to moderately suitable for irrigation. A correlation study was conducted to find out the mutual associations among the variables. Piper diagram indicated the overall chemical nature of the study area was calcium-magnesium bicarbonate type. Cluster analysis revealed mutual apportionment of various parameters in the groundwater of the Peshawar basin, Pakistan.

Effects of Monensin and Fish Oil on Conjugated Linoleic Acid Production by Rumen Microbes in Holstein Cows Fed Diets Supplemented with Soybean Oil and Sodium Bicarbonate

  • Jin, G.L.;Choi, S.H.;Lee, H.G.;Kim, Y.J.;Song, Man K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.12
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    • pp.1728-1735
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    • 2008
  • The present study was conducted with four ruminally canulated Holstein cows to observe the effects of monensin or fish oil on diet fermentation and production of conjugated linoleic acids (CLAs) in the rumen when fed diets supplemented with soybean oil and sodium bicarbonate. Cows of the control treatment were fed a basal diet (CON) consisting of 60% commercial concentrate and 40% chopped rye grass hay. Cows of other treatments were fed the same diet as CON, but the concentrate was supplemented with 7% of soybean oil and 0.5% of sodium bicarbonate (SO-B), SO-B supplemented with monensin (30 ppm, SO-BM) or concentrate supplemented with 6.3% of soybean oil, 0.5% of sodium-bicarbonate, 30 ppm of monensin and 0.7% of fish oil (SO-BMF). Dry matter (DM) intake of the cows was significantly (p<0.011) reduced by feeding the SO-BMF diet compared to the other diets which did not differ in DM intake. Whole tract digestibility of major dietary components was significantly (p<0.004-0.027) higher for SO-BMF than the other supplement-containing diets. Dietary supplements did not clearly affect rumen pH and ammonia concentrations compared to the CON diet. Significantly reduced (p<0.05) total VFA concentration was obtained by the addition of fish oil to the diet (SO-BMF) compared to other diets. No differences, however, were obtained in major VFA proportions as well as in total VFA between the supplemented diets. The SO-BM diet increased (p<0.01-0.05) the concentrations of trans-11 $C_{18:1}$ and linoleic acid in rumen fluid. Total CLA concentration was also increased by the feeding of SO-B and SO-BM diets during early fermentation times (up to 3 h) post-feeding. Cis-9, trans-11 CLA concentration in rumen fluid was highest (p<0.05) for SO-B up to 1 h while the highest (p<0.01) value for SO-BM occurred at 3 h post-feeding. An increased trans-10, cis-12 CLA concentration was obtained from the SO-B and SO-BM diets at 1 and 3 h post feeding compared to the other diets. Supplementation of oils with monensin and sodium bicarbonate increased (p<0.05) the proportions of $C_{18:1}$ and CLA in the plasma of cows, but the effect of monensin and/or fish oil was limited to trans-10, cis-12 CLA.

Extending the Storage Periods of Zanthoxylum schinifolium Seed Oil using Sodium Bicarbonate and Ascorbic Acid (중탄산나트륨과 아스코르브산을 이용한 산초유의 저장기간 연장)

  • Kim, Hak Gon;Kang, Seung Mi;Yong, Seong Hyeon;Seol, Yu Won;Kim, Do Hyeon;Park, Jun Ho;Yu, Chan Yeol;Choi, Myung Suk
    • Korean Journal of Medicinal Crop Science
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    • v.28 no.6
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    • pp.421-427
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    • 2020
  • Morus alba, Anti-obesity, C57BL/6 Mice, Expression, Flavonoid, Gene, Mulberry Background: The seed oil of Zanthoxylum schinifolium S. et Z. (sancho) is a traditional cooking oil that has long been sold at a very high price however, depending on the method of extraction and storage, this oil becomes rancid occurs very quickly. Therefore, this study aimed to find a material that prevents rancidity and improves the storage properties of sancho oil. Methods and Results: Sancho oil was extracted using an extraction press, and acid values were compared with commercially available vegetable oils, sancho oil had a higher acid value than other vegetable oils. A very high acid value was observed in sancho oil stored for 6 months, regardless of temperature, requiring an effective storage method. The high acid value and the decrease in turbidity of sancho oil are dependent on the days of sedimentation. Treatment with sodium bicarbonate by concentration resulted in minimal changes in acid value over time. However, minor differences were detected among the treatment concentrations. Ascorbic acid was added to maximize the effect of sodium bicarbonate, and it was observed that ascorbic acid did not improve the antioxidant effect. The sodium bicarbonate and ascorbic acid mixture resulted in minimal change in acid value at temperature up to 25℃. Conclusions: Sancho oil becomes rancid very quicky and requires efficient storage techniques. Sodium bicarbonate and ascorbic acid have been proven to be useful as safe anti-racidity agents without causing harm to humans.