• Title/Summary/Keyword: Smooth flow

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Binding Interaction Analysis of Neuromedin U Receptor 1 with the Native Protein Neuromedin U

  • Nagarajan, Santhosh Kumar;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.10 no.1
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    • pp.14-19
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    • 2017
  • Neuromedin, a neuropeptide, which is involved in various functions that include contractile activity on smooth muscle, controlling the blood flow and ion transport in the intestine, increased blood pressure and regulation of adrenocortical function. It is involved in the pathophysiology of various immune mediated inflammatory diseases like asthma. In this study, we have performed protein-protein docking analysis of neuromedin U - neuromedin U receptor 1 complex. We have developed homology models of neuromedin U, and selected a reliable model using model validation. The model was docked with the receptor model, to analyse the crucial interactions of the complex. This study could be helpful as a tool in developing novel and potent drugs for the diseases related with neuromedin U receptor 1.

The Practical Application on Super Flowing Concrete (Inchon subway 1-10 section) (초유동 콘크리트의 적용사례)

  • 박칠림;김성원;안재현;권영호;이상수
    • Proceedings of the Korea Concrete Institute Conference
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    • 1998.10b
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    • pp.916-921
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    • 1998
  • This study describes the result for the placement of the super flowing concrete(SFC) in under-pinning-top-slab which is located Inchon subway section 1-10 where, due to heavy reinforcements and limited working space, it was difficult to place concrete. After placing 600㎥, smooth construction and quality control were possible due to the good flow-ability, self-fillingability, and the resistance of segregation of the SFC itself. Furthermore, economical efficiency was obtained through not only the reduction of the works, labors, and site noise but also the efficient construction control. Because of the crack prevention, high strength, and a fine concrete surface, this study could be considered as a momentum to be adopted generally for applying the proposed method to the difficult subway construction area in the near future.

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An Immersed-Boundary Method for Simulation of Density-Stratified Flows (밀도 성층 유동 해석을 위한 가상경계법)

  • Yoon, Dong-Hyeog;Yang, Kyung-Soo;Hwang, Jong-Yeon;Lee, Sung-Su
    • Proceedings of the KSME Conference
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    • 2004.04a
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    • pp.1909-1914
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    • 2004
  • An immersed boundary method for simulation of density-stratified flows is developed and applied to computation of viscous flows over two-dimensional obstacles in a bounded domain under stable density stratification. Density sources/sinks are introduced on the body surface. Two obstacle shapes are used, a vertical barrier and a smooth cosine-shaped hill; weak stratification, defined by $K=ND/{\pi}U{\leq}1$, where U, N, and D are the upstream velocity, buoyancy frequency, and domain height, respectively, is considered. The results are consistent with other authors' calculations, and shed light on computation of density-stratified flows in complex geometries.

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Non-gray Radiation with Turbulent Convection in the Entrance Region of a Smooth Tube (매끈한 튜브의 입구 영역에서 난류유동에 의한 대류와 비회복사)

  • Seo, T.B.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.7 no.4
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    • pp.667-680
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    • 1995
  • 튜브 내의 입구영역에서 난류 유동에 의한 대류와 비회복사(non-gray radiation)가 동시에 일어날 때의 열전달특성을 수치해석적으로 연구하였다. 작동유체는 이산화탄소, 수증기, 질소의 혼합가스라고 가정하였다. 지배방정식을 계산하기 위해 유한차분법이 이용되었고, 복사전달방정식을 이차편미분방정식으로 바꾸기 위해 P-1 근사법이 사용되었다. 그리고 혼합가스의 비회흡수계수(non-gray absorption coefficient)는 지수광폭밴드모형(exponential wide band model)을 이용해서 구하였다. 열전달특성에 대한 온도조건의 영향을 조사하기 위해 튜브의 축방향에 대한 평균 온도와 뉴셀트수(Nusselt number)의 변화를 몇 가지 다른 온도조건에 대해 나타내었다. 또한, 가스의 성분조성에 대한 영향을 조사하였으며, 이러한 결과에 기초해서 튜브 내에서 난류유동에 의한 대류와 비화복사가 동시에 일어날 때의 복사 뉴셀트수를 쉽게 예측할 수 있는 방법을 제시하였다.

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Study on Turnout System(Rubber Wheel Type) & Guideway for AGT (고물차륜용 경량전철 분기기 및 안내궤조에 대한 연구)

  • Park June-Taek;Kim Soon-Chul;Kim Jun-Sik;Lee An-Ho;Seong Tack-Ryong
    • Proceedings of the KSR Conference
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    • 2003.05a
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    • pp.349-355
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    • 2003
  • Traffic congestion caused by cverpopulation has a major detrimental effect on bringing about social and economic problems ia city area. Therefore Un order to maintain and sustain smooth flow of railway system, we are willing to introduce Light Rail Transit System. Rubber wheel type and guideway far AGT have been concentrated on our study Especially, the prototype of LRT turnout system has been developed. Furthermore, the structural analysis for the guideway system has been completed to secure reliability for the LRT system. In the near future, the tumout system of rubber wheel and guideway shall be applied in Korea. We hope reliability fer the system shall be secured without any major difficulties. As a result, we expect to expedite the localization of rubber wheel type and guideway for AGT.

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Experimental Studies on Heat Transfer in the Annuli with Corrugated Tubes (파형관을 가진 이중 환형관의 열전달에 관한 실험적 연구)

  • 안수환;손강필
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.14 no.8
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    • pp.683-689
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    • 2002
  • This paper is to present the results of a comprehensive study on heat transfer in annuli with spirally corrugated inner tubes in the turbulent regime. Tube surface-temperature measurements were used to explain the enhancement phenomena in the annuli with several different corrugated tubes. Nusselt numbers were between 1.1 and 2 times the smooth annulus values. These enhancement values can be used to determine the appropriate range of applicability for spirally corrugated annuli.

Biped Walking of Hydraulic Humanoid Robot on Inclined Floors (유압식 이족 휴머노이드 로봇의 경사면 보행 연구)

  • Kim, Jung-Yup
    • Journal of Institute of Control, Robotics and Systems
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    • v.18 no.3
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    • pp.258-266
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    • 2012
  • This paper describes a biped walking algorithm for a hydraulic humanoid robot on inclined floors. To realize stable and robust biped walking, the walking algorithm was divided into five control strategies. The first is a joint position control strategy. This strategy is for tracking desired joint position trajectories with a gain switching. The second is a multi-model based ZMP (Zero Moment Point) control strategy for dynamic balance. The third is a walking pattern flow control strategy for smooth transition from step to step. The fourth is an ankle compliance control, which increases the dynamic stability at the moment of floor contact. The last is an upright pose control strategy for robust walking on an inclined floor. All strategies are based on simple pendulum models and include practical sensory feedback in order to implement the strategies on a physical robot. Finally, the performance of the control strategies are evaluated and verified through dynamic simulations of a hydraulic humanoid on level and inclined floors.

Wind loading characteristics of super-large cooling towers

  • Zhao, L.;Ge, Y.J.
    • Wind and Structures
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    • v.13 no.3
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    • pp.257-273
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    • 2010
  • The aerodynamic and aero-elastic model tests of the China''s highest cooling tower has been carried out in the TJ-3 Boundary Layer Wind Tunnel of Tongji University. By adopting a scanivalve system, the external wind pressure is firstly measured on $12{\times}36$ taps for a single tower, two and four grouped towers under the condition of both smooth flow and the boundary layer due to surrounding geographic and building topography. The measurements of internal wind pressure distribution of $6{\times}36$ taps are taken for a single tower under the various ventilation ratios ranging from 0% to 100% of stuffing layers located at the bottom of the tower. In the last stage, the wind tunnel tests with an aero-elastic model are carefully conducted to determine wind-induced displacements at six levels (each with eight points) with laser displacement sensors. According to the measurement results of wind pressure or vibration response, the extreme aerodynamic loading values of the single or grouped towers are accordingly analyzed based on probability correlation technique.

Development of A Manufacturing Desk for Distributed Manufacturing Systems Over the World Wide Web (분산제조 시스템에서 웹을 이용한 제조정보 지원 채널 개발)

  • Lee, Hong-Hee;Choi, Hong-Geun
    • IE interfaces
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    • v.16 no.1
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    • pp.1-7
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    • 2003
  • Today's manufacturing enterprise relies heavily on the collaboration and coordination among the distributed manufacturing systems. The effective exchange of the various manufacturing information among the distributed organizations contributes a great deal to their productivity. An Internet-Based Manufacturing Desk is developed for the production of the press dies in the automobile industry in order to solve the manufacturing problems among the distributed organizations, to maintain their smooth and immediate information flow, and to increase their productivity finally. The CBR(Case-Based Reasoning) method is applied to achieve those effects. Using the method, the solutions and methods of the predetermined case-bases are retrieved and applied to solve a newly introduced problem. The developed system is implemented and applied successfully.

The Study on Characteristics of Water Spray and Droplet from Fire Sprinkler Head (소화용 스프링클러 헤드의 살수분포 및 수적 특성에 대한 연구)

  • 추병길;최종욱;차경세
    • Journal of the Korean Society of Safety
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    • v.16 no.2
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    • pp.13-21
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    • 2001
  • The effect of water spray for the fire sprinkler depends on droples distribution over maximum possible floor area. The present study are carried out for the characteristics of water spray and droplets experimentally and numerically km two fire sprinkler heads which are CHM head and CHl heal CHl head is self-production and CHl head is widely used up to date. As the result of using CHM head, water spray and droplets are distributed over large area because CHM head has smooth surface and non-flamed shape. When the pressure of fire sprinkler head is low, SMD(sauter mean diameter) is large and when the pressure of fire sprinkler head is high, SMD is small.

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