• 한국광학회지
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• 제15권4호
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• pp.349-354
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• 2004

XFP(10 Gb/s Small Form Factor Pluggable) 트랜시버 모듈에 사용되는 광송신 서브어셈블리(TOSA: Transmitter Optical Sub-assembly)를 열적, 전기적 측면에서 설계, 제작 및 평가하였다. 저가격이며 소형인 TOSA를 제작하기 위해서 바이어스 티 및 정합저항등을 AlN서브마운트 위에 집적하였다. 10 Gb/s의 초고속 전기 신호의 입력을 위해 CPW형 마이크로파 전송로를 스템 구조체내에 도입하였다. 소자의 전기적 특성 분석을 위해 서브마운트내에 실장되는 각종 전기광학 부품들과 스템 구조체들을 고속회로 모델링 하였다. 제작한 TOSA의 특성평가를 통해, 85$^{\circ}C$에서 11 GHz 이상의 -3 dB 대역폭을 얻을 수 있었다.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 추계학술대회논문집
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• pp.406-411
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• 2003

One of the trends on information storage device is focused on the development of micro-optical devices with OFH (Optical Flying Head). Many different types of sliders for OFH and optical component systems have been introduced in the literature. However, the important issue on the mechanical system, which consists of suspension, swing arm and VCM (Voice Coil Motor) part has not been discussed up to date. In this research, we analyses the suspension, which is used for the small form factor MO drive. The analysis is in process two ways. One is probabilistic analysis, another is dynamic shock analysis. Probabilistic analysis is a technique you can use to assess the effect of uncertain input parameters and assumptions on your analysis model. Using a probabilistic analysis you can and out how much the results of a finite elements analysis are affected by uncertainties in the model. Dynamic shock analysis is used for the mobile applications. The mechanical robustness of the suspension simulating the shock responses of a disk-suspension is proposed in this paper.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 추계학술대회논문집
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• pp.424-429
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• 2003

This paper proposes a swing-arm type dual-stage actuator, which consists of a PZT actuator for fine motion and a VCM(Voice Coil Motor) for coarse motion, for SFF ODD(Small Form Factor Optical Disk Drive), in order to achieve fast access speed and precise track following control. We focus our attention on the design and control of the PZT actuator, because there have been a lot of previous researches related to the VCM and dual-stage actuators. Due to the dual cantilever structure, the PZT actuator can generate precise translational tracking motion at its tip where optical pickup is attached at, and the effect of hysteric behavior of the PZT element is reduced. The dynamic model of the PZT actuator is derived by using the Hamilton's principle, and verified by comparing with the experimental frequency response. The sliding mode control is designed in order to be robust against modeling uncertainties. Simulations and experimental results confirm the effectiveness of the suggested control scheme.

• 정보저장시스템학회:학술대회논문집
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• 정보저장시스템학회 2005년도 추계학술대회 논문집
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• pp.154-159
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• 2005

The next generation of optical storage systems requires higher numerical aperture (NA) objective lenses and shorter wavelength laser in order to improve the unit areal density. A blu-ray technology satisfies a miniaturization and a high capacity which are the requirements of the portable device. In this paper, we analyze the optical performance of hybrid micro lens and do active alignment. The hybrid micro lens is manufactured by using a wafer based fabrication technology. Optical components of hybrid micro lens are evaluated. The measurement of the optical power, the spot size and the wavefront error awe performed to evaluate the hybrid micro lens with NA 0.85. Using the measured data, we estimate if the performance of hybrid micro lens corresponds to the designed performance. After the performance of hybrid micro lens is evaluated, the integrated optical pickup and the hybrid micro lens are assembled by active alignment using UV curing and the optical performance of SFFOP is satisfied with BD specifications.

• 정보저장시스템학회논문집
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• 제2권1호
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• pp.79-84
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• 2006

The next generation of optical storage systems requires higher numerical aperture(NA) objective lenses and shorter wavelength laser in order to improve the unit areal density. A blu-ray technology satisfies a miniaturization and a high capacity which are the requirements of the portable device. In this paper, we analyze the optical performance of hybrid micro lens and do active alignment. The hybrid micro lens is manufactured by using a wafer based fabrication technology. Optical components of hybrid micro lens are evaluated. The measurement of the optical power, the spot size and the wavefront error are performed to evaluate the hybrid micro lens with NA 0.85. Using the measured data, we estimate if the performance of hybrid micro lens corresponds to the designed performance. After the performance of hybrid micro lens is evaluated. the integrated optical pickup and the hybrid micro lens are assembled by active alignment using UV curing and the optical performance of SFFOP is satisfied with BD specifications.

• BMB Reports
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• 제40권4호
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• pp.554-561
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• 2007

Shen and colleagues (Lin et al., 2004) have recently shown that overexpression of the Drosophila DNA methyltransferase 2 isoform C, dDnmt2c, extended life span of fruit flies, probably due to increased expression of small heat shock proteins such as Hsp22 or Hsp26. Here, I demonstrate with immunoprecipitations that overexpressed dDnmt2c interacts with endogenous Hsp70 protein in vivo in S2 cells. However, its C-terminal half, dDnmt2c(178-345) forms approximately 10-fold more Hsp70-containing protein complexe than wild-type dDnmt2c. Overexpressed dDnmt2c(178-345) but not the full length dDnmt2c is able to increase endogenous mRNA levels of the small heat shock proteins, Hsp26 and Hsp22. I provide evidence that dDnmt2c(178-345) increases Hsp26 promoter activity via two heat shock elements, HSE6 and HSE7. Simultaneously overexpressed Hsp40 or a dominant negative form of heat shock factor abrogates the dDnmt2c(178-345)-dependent increase in Hsp26 transcription. The data support a model in which the activation of heat shock factor normally found as an inactive monomer bound to chaperones is linked to the overexpressed C-terminus of dDnmt2c. Despite the differences observed in flies and S2 cells, these findings provide a possible explanation for the extended lifespan in dDnmt2c-overexpressing flies with increased levels of small heat shock proteins.

• The Journal of Asian Finance, Economics and Business
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• 제9권3호
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• pp.203-215
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• 2022

Bayesian Networks are multivariate probabilistic factor graphs that are used to assess underlying factor relationships. From January 2005 to December 2018, the study examines how Dynamic Bayesian Networks can be utilized to estimate portfolio risk and return as well as determine inter-factor relationships among reversal profit-generating components in Pakistan's emerging market (PSX). The goal of this article is to uncover the factors that cause reversal profits in the Pakistani stock market. In visual form, Bayesian networks can generate causal and inferential probabilistic relationships. Investors might update their stock return values in the network simultaneously with fresh market information, resulting in a dynamic shift in portfolio risk distribution across the networks. The findings show that investments in low net profit margin, low investment, and high volatility-based designed portfolios yield the biggest dynamical reversal profits. The main triggering aspects related to generation reversal profits in the Pakistan market, in the long run, are net profit margin, market risk premium, investment, size, and volatility factor. Investors should invest in and build portfolios with small companies that have a low price-to-earnings ratio, small earnings per share, and minimal volatility, according to the most likely explanation.

• Nuclear Engineering and Technology
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• 제56권1호
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• pp.241-246
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• 2024

The study was carried out by numerical integration based on the diffraction properties and elemental composition. The elemental compositions of breast tissues in the literature were tested. The photon attenuation coefficients calculated using the recent elemental composition were found within 0.2-16% for adipose tissue and within 0.04-17% for glandular tissue with the experimental reference data. The attenuation coefficients of cancerous breast tissue calculated according to the elemental content previously measured in breast cancer patients were found within 0-17% with experimental data in the literature. The attenuation coefficients are of great interest to medical research. To calculate realistic attenuation coefficients, the characteristic coherent scatter, which is most intense at small angles, must be considered. For this reason, experimentally measured form factor data were reviewed, and the most compatible one with the theoretical form factor data produced in this study was used at low momentum transfer x (0 < x ≤ 8 nm^-1). The differential linear coherent scattering distributions were calculated for an energy value of 17.44 keV and compared with their experimental counterparts.

• 폴리머
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• 제33권5호
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• pp.485-489
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• 2009

중수소화 폴리스티렌-폴리에틸렌옥사이드 이중블록공중합체(dPS-PEO)로 형성된 미셀의 구조에 대한 온도 의존성을 소각중성자산란(SANS)을 이용하여 조사하였다. SANS 데이터는 코어-쉘 모델의 form factor와 hard-sphere structure factor를 결합하여 분석하였으며, 산란 곡선 맞춤을 이용하여 미셀 응집수와 코로나 반경을 구하였다. 온도가 $25^{\circ}C$에서 $45^{\circ}C$로 증가함에 따라서 미셀 응집수는 229에서 240으로 변화하였으며, 이로 인해 코어 반경이 증가하였다. 그러나, 미셀의 쉘 두께는 6.2 nm에서 5.8 nm로 감소하였다. 이러한 구조적 변화는 온도 증가에 따라서 PEO 블록의 소수성이 증가함으로써 코로나 내의 친수성 그룹 당 수화 부피가 감소하였기 때문이다.

• BMB Reports
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• 제51권9호
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• pp.429-436
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• 2018

Fructose in the form of sucrose and high fructose corn syrup is absorbed by the intestinal transporter and mainly metabolized in the small intestine. However, excess intake of fructose overwhelms the absorptive capacity of the small intestine, leading to fructose malabsorption. Carbohydrate response element-binding protein (ChREBP) is a basic helix-loop-helix leucine zipper transcription factor that plays a key role in glycolytic and lipogenic gene expression in response to carbohydrate consumption. While ChREBP was initially identified as a glucose-responsive factor in the liver, recent evidence suggests that ChREBP is essential for fructose-induced lipogenesis and gluconeogenesis in the small intestine as well as in the liver. We recently identified that the loss of ChREBP leads to fructose intolerance via insufficient induction of genes involved in fructose transport and metabolism in the intestine. As fructose consumption is increasing and closely associated with metabolic and gastrointestinal diseases, a comprehensive understanding of cellular fructose sensing and metabolism via ChREBP may uncover new therapeutic opportunities. In this mini review, we briefly summarize recent progress in intestinal fructose metabolism, regulation and function of ChREBP by fructose, and delineate the potential mechanisms by which excessive fructose consumption may lead to irritable bowel syndrome.