• Title/Summary/Keyword: Small Sample

Search Result 2,235, Processing Time 0.03 seconds

Effect of Genetic Correlations on the P Values from Randomization Test and Detection of Significant Gene Groups (유전자 연관성이 랜덤검정 P값과 유의 유전자군의 탐색에 미치는 영향)

  • Yi, Mi-Sung;Song, Hae-Hiang
    • The Korean Journal of Applied Statistics
    • /
    • v.22 no.4
    • /
    • pp.781-792
    • /
    • 2009
  • At an early stage of genomic investigations, a small sample of microarrays is used in gene expression experiments to identify small subsets of candidate genes for a further accurate investigation. Unlike the statistical analysis methods for a large sample of microarrays, an appropriate statistical method for identifying small subsets is a randomization test that provides exact P values. These exact P values from a randomization test for a small sample of microarrays are discrete. The possible existence of differentially expressed genes in the sample of a full set of genes can be tested for the null hypothesis of a uniform distribution. Subsets of smaller P values are of prime interest for a further accurate investigation and identifying these outlier cells from a multinomial distribution of P values is possible by M test of Fuchs et al. (1980). Above all, the genome-wide gene expressions in microarrays are correlated, but the majority of statistical analysis methods in the microarray analysis are based on an independence assumption of genes and ignore the possibly correlated expression levels. We investigated with simulation studies the effect that correlated gene expression levels could have on the randomization test results and M test results, and found that the effects are often not ignorable.

Evaluation of Corrosivity of Antifreeze for Automobiles Containing Non-amine Type Corrosion Inhibitors for Copper (Non-amine계 부식방지제를 포함하는 자동차용 부동액의 구리 부식성 평가)

  • Soh, Soon-Young;Chun, Yong-Jin;Park, In-Ha;Han, Sang-Mi;Jang, Hee-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.21 no.2
    • /
    • pp.619-626
    • /
    • 2020
  • The development of new antifreeze mixtures containing non-amine-type corrosion inhibitors, which considers environmental protection, has become a major issue. In this study, four non-amine-type corrosion inhibitors were synthesized and used to produce five kinds of new antifreeze for automobiles to evaluate the rate of copper corrosion. The effects were evaluated by the weight change, surface observation, roughness measurement, and measurement of copper elution in the solution. The amount of copper eluted measured by ICP from Sample 4 was small, and the elution rate was prolonged. Sample 4 showed the best anti-corrosion performance owing to a corrosion suppression effect by passivating copper because the metal surface was smooth after the test, and the corrosion product layer was formed evenly on the surface as small local corrosion was observed. The major corrosion inhibitor added to Sample 4 was 1-aminomethyl(N',N'-di(2-hydroxyethyl)benzotrazole, which contained a certain amount in Sample 5 to show relatively high local corrosion but passivation in progress. Therefore, among the four corrosion inhibitors, 1-aminomethyl(N',N'-di(2-hydroxyethyl)benzotrazole had the highest corrosion inhibitory effect. This corrosion inhibitor prevents corrosion by promoting the passivation of copper on the antifreeze.

Variable Cut-off Frequency and Variable Sample Rate Small-Area Multi-Channel Digital Filter for Telemetry System (텔레메트리 시스템을 위한 가변 컷 오프 주파수 및 가변 샘플 레이트 저면적 다채널 디지털 필터 설계)

  • Kim, Ho-keun;Kim, Jong-guk;Kim, Bok-ki;Lee, Nam-sik
    • Journal of Advanced Navigation Technology
    • /
    • v.25 no.5
    • /
    • pp.363-369
    • /
    • 2021
  • In this paper, We propose variable cut-off frequency and variable sample rate small-area multi-channel digital filter for telemetry system. Proposed digital filter reduced hardware area by implementing filter banks that can variably use cut-off frequency and sample rate without additional filter banks for an arbitrary cut ratio. In addition, We propose the architecture in which sample rate can variably be selected according to the number of filters that pass through the multiplexer control. By using time division multiplexing (TDM) supported by the finite impulse response (FIR) intellectual property (IP) of Quartus, the proposed digital filter can greatly reduce digital signal processing (DSP) blocks from 80 to 1 compared without TDM. Proposed digital filter calculated order and coefficients using Kaiser window function in Matlab, and implemented using very high speed integrated circuits hardware descryption language (VHDL). After applying to the telemetry system, we confirmed that the proposed digital filter was operating through the experimental results in the test environment.

Redesigning KNSO s Household Survey Sample (통계청 가구부문 조사의 표본설계)

  • 윤연옥;김규영;이명호
    • Survey Research
    • /
    • v.5 no.1
    • /
    • pp.103-130
    • /
    • 2004
  • Main monthly household surveys conducted by Korea National Statistical Office are economically active population survey(EAPS) and household income and expenditure survey(HIES). Samples of these two surveys are redesigned every 5 years based on Census. This paper is about sample redesign of household survey conducted in 2002 based on 2000 Census. Main improvements of 2002 sample redesign are the introduction of rotation sampling system, the expansion of HIES survey area from urban to whole country and the foundation of basement to make small area estimation for the unemployment statistics. Also the number of sample households within a enumeration district(ED) is reduced from 24 to 20. That makes it possible to select more ED samples which provides better precision for EAPS and HIES. To select representative samples for the population, different classification index is used for each metropolitan area and provinces.

  • PDF

Low Temperature Sintering of (Bi1/2Na1/2)TiO3-SrTiO3 Ceramics and Their Ferroelectric and Piezoelectric Properties (BNT-ST 세라믹스의 저온 소결과 강유전 및 압전 특성)

  • Hyunhee Kwon;Ga Hui Hwang;Chae Il Cheon;Ki-Woong Chae
    • Journal of Sensor Science and Technology
    • /
    • v.32 no.4
    • /
    • pp.238-245
    • /
    • 2023
  • 0.75(Bi1/2Na1/2)TiO3-0.25SrTiO3 (BNT-25ST) ceramics with high densities were successfully prepared at a sintering temperature of 1,000℃ by adding a mixture of 1 mol% CuO and 0.5 mol% Na2CO3 or 0.5 mol% CuO and 0.25 mol% Na2CO3. Double polarization-electric field (P-E) hysteresis curves and sprout-shaped bipolar strain-electric field (S-E) hysteresis curves with small negative strains were observed in the pristine and CuO-added BNT-25ST ceramics whereas the Na2CO3-added sample showed similar P-E and S-E curves to a typical ferroelectric. The pristine BNT-25ST ceramics showed an extremely large strain and a large-signal piezoelectric strain constant (d33*): 0.287 % at 80 kV/cm and 850 pm/V at 20 kV/cm. Similar values, 0.248 % at 80 kV/cm and 655 pm/V at 20 kV/cm, were obtained in the CuO-added sample. However, the pristine and CuO-added samples showed large hysteresis in unipolar S-E curves at an electric field of less than 20 kV/cm. The Na2CO3-added sample showed smaller values of the strain and d33* but displayed a linear change and small hysteresis in the unipolar S-E curve. The co-added sample with CuO and Na2CO3 displayed intermediate P-E and S-E hysteresis curves.

Tail Probability Approximations for the Ratio of the Independent Random Variables

  • Cho, Dae-Hyeon
    • Journal of the Korean Data and Information Science Society
    • /
    • v.7 no.2
    • /
    • pp.189-201
    • /
    • 1996
  • In this paper, we study the saddlepoint approximations for the ratio of independent random variables. In Section 2, we derive the saddlepoint approximation to the density. And in Section 3, we derive two approximation formulae for the tail probability, one by following Daniels'(1987) method and the other by following Lugannani and Rice's (1980). In Section 4, we represent some numerical examples which show that the errors are small even for small sample size.

  • PDF

CUSUM Chart to Monitor Dispersion Matrix for Multivariate Normal Process

  • Chang, Duk-Joon;Kwon, Yong-Man;Hong, Yeon-Woong
    • 한국데이터정보과학회:학술대회논문집
    • /
    • 2003.05a
    • /
    • pp.89-95
    • /
    • 2003
  • Cumulative sum(CUSUM) control charts for monitoring dispersion matrix under multivariate normal process are proposed. Performances of the proposed CUSUM charts are measured in terms of average run length(ARL) by simulation. Numerical results show that small reference values of the proposed CUSUM chart is more efficient for small shifts in the production process.

  • PDF

Command to line of sight guidance loop based on LQG design (LQG 설계에 의한 시선지령 유도루우프의 구성)

  • Chang, Sang-Keun;Lyou, Joon
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 1992.10a
    • /
    • pp.567-571
    • /
    • 1992
  • A guidance loop of the missile system which uses a command to line of sight(CLOS) guidance law is designed based on LQG theory. In the environment of the severe tracking system noise, the system requires small aerodynamic control fin travel and small miss distance simultaneously. Results from a sample airframe shows good performance against a randomly maneuvering target.

  • PDF

Tail Probability Approximations for the Ratio of two Independent Sequences of Random Variables

  • Cho, Dae-Hyeon
    • Journal of the Korean Data and Information Science Society
    • /
    • v.10 no.2
    • /
    • pp.415-428
    • /
    • 1999
  • In this paper, we study the saddlepoint approximations for the ratio of two independent sequences of random variables. In Section 2, we review the saddlepoint approximation to the probability density function. In section 3, we derive an saddlepoint approximation formular for the tail probability by following Daniels'(1987) method. In Section 4, we represent a numerical example which shows that the errors are small even for small sample size.

  • PDF

Estimation of Mean Residual Life under Random Censorship Model Using Partial Moment Approximation

  • Park, Byung Gu;Lee, Jae Man;Cha, Young Joon
    • Journal of Korean Society for Quality Management
    • /
    • v.22 no.3
    • /
    • pp.111-118
    • /
    • 1994
  • In this paper we propose a parametric and a nonparametric small sample estimators for the mean residual life (MRL) under the random censorship model using the partial moment approximation. We also compare the proposed nonparametric estimator with the well-known nonparametric MRL estimator based on Kaplan-Meier estimator of the survival function, and present the efficiency of the nonparametric method relative to the Weibull model for small samples.

  • PDF