• Title/Summary/Keyword: Small Domains

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Effect of Horizontal Eye Movements on the Heart Rate Variability after Exposure to a Fear-Inducing Film Clip (공포 영화 장면 노출 후 수평적 안구 운동이 심박수 변이도에 미치는 영향)

  • Lee, Haewon;Yum, Myung-Kul;Kim, Seok Hyeon;Lee, Yun Jeong;Kim, Daeho
    • Korean Journal of Biological Psychiatry
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    • v.15 no.1
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    • pp.35-45
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    • 2008
  • Objectives : There has been a continued debate regarding the role of eye movements in Eye Movement Desensitization and Reprocessing(EMDR). This study examined the possible autonomic effect of horizontal eye movements after being exposed to fearful stimuli. Methods : Fifty two healthy adult women were randomly allocated to eye movement or eye fixed groups after watching a five minute fear-inducing film clip. ECG was recorded during the resting state, after watching the clip, and the treatment. A spectral power analysis of the heart rate variability was performed. As the variables violated the rule of normal distribution and the number in each group is small the non-parametric test was used. Results : Overall, we did not find the differences between the groups in both time and frequency domains. Some minor differences found were not consistent with results from previous studies. Conclusions : Effect of eye movement on autonomic nervous system during fear desensitization was not supported in this experiment. Further study with other psychophysiological measures is needed to understand the role of eye movements in treatment of traumatic memory.

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Molecular Cloning, Tissue Distribution and Expression of Porcine y+L Amino Acid Transporter-1

  • Zhi, Ai-min;Zhou, Xiang-yan;Zuo, Jian-jun;Zou, Shi-geng;Huang, Zhi-yi;Wang, Xiao-lan;Tao, Lin;Feng, Ding-yuan
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.2
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    • pp.272-278
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    • 2010
  • In this study, we cloned, sequenced and characterized porcine y+L Amino Acid Transporter-1 (y+LAT1). By screening a translated EST database with the protein sequence of the human $y^{+}$LAT1 and by using rapid amplification of cDNA ends (RACE), the full-length cDNA encoding porcine $y^{+}$LAT1 was isolated from porcine intestine RNA. It was 2,111 bp long, encoding a 511 amino acid trans-membrane glycoprotein composed of 12 transmembrane domains. The predicted amino acid sequence was found to be 91%, 90%, 87% and 87% identical to those of cattle, human, mouse and rat $y^{+}$LAT1 respectively. Real-time RT-PCR results indicated that the small intestine had the highest $y^{+}$LAT1 mRNA abundance and the lung had the lowest $y^{+}$LAT1 mRNA abundance. Baby hamster kidney (BHK) cells transfected with green fluorescent protein (GFP) tagged porcine $y^{+}$LAT1 cDNA indicated that the cellular localization of the gene product in BHK was on the plasma membrane.

Data Partitioning on MapReduce by Leveraging Data Utility (맵리듀스에서 데이터의 유용성을 이용한 데이터 분할 기법)

  • Kim, Jong Wook
    • Journal of Korea Multimedia Society
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    • v.16 no.5
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    • pp.657-666
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    • 2013
  • Today, many aspects of our lives are characterized by the rapid influx of large amounts of data from various application domains. The applications that produce this massive of data span a large spectrum, from social media to business intelligence or biology. This massive influx of data necessitates large scale parallelism for efficiently supporting a large class of analysis tasks. Recently, there have been extensive studies in using MapReduce framework to support large parallelism. While this technique has produced impressive results in diverse applications, the same can not be said for multimedia applications where most of users are interested in a small number of results having high or low score. Thus, in this paper, we develop the data partitioning algorithm which is able to efficiently process large data set having different data utility. The experiment results show that the proposed technique provides significant execution time gains over the existing solution.

Design and Implementation of Low-Power Technique based on Monitoring Workload on Real-Time Operating Systems (실시간 운영체제에서 작업량 관찰에 기반한 저전력 기법의 설계 및 구현)

  • Cho, Moon-Haeng;Jung, Myoung-Jo;Kim, Yong-Hee;Lee, Cheol-Hoon
    • The Journal of the Korea Contents Association
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    • v.7 no.6
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    • pp.69-78
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    • 2007
  • In recent years, embedded mobile systems have been expanding their application domains from embedded portable devices which only execute a specialized application such as MP3 player or digital camcoder to digital convergence devices which execute more complicated applications converged various functionalities such as video and audio play, digital dictionary, DMB, games, phone, etc. As it requires the increasing hardware performance such as more faster CPU and more larger RAM, display, disk size, it has brought about a corresponding increase in power consumption. However, coupled with relatively small gains in battery capacity over recent years, the importance of software architecture including intelligent power management has become paramount. In this paper, we have ported UbiFOSTM with energy saving techniques on the ARM9-based MBA2440 platform. For energy savings, we adapted the dynamic power management and the device power management schemes based on monitoring workload. Experimental results with some well-known applications show that proposed low power technique could save energy up to 24 %.

Formation Mechanism of Mesoporous Aluminum Hydroxide Film by Alkali Surface Modification (알칼리 표면개질을 통한 메조포러스 알루미늄 하이드록사이드 필름 형성 기구)

  • Seo, Young-Ik;Jeon, Yong-Jin;Lee, Young-Jung;Kim, Dae-Gun;Lee, Kyu-Hwan;Kim, Young-Do
    • Korean Journal of Materials Research
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    • v.20 no.2
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    • pp.97-103
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    • 2010
  • In this study, a new, relatively simple fabrication method for forming a mesoporous $Al(OH)_3$ film on Al substrates was demonstrated. This method, i.e., alkali surface modification, was simply comprised of dipping the substrate in a $5\times10^{-3}$ M NaOH solution at $80^{\circ}C$ for one minute and then immersing it in boiling water for 30 minutes. After alkali surface modification, a mesoporous $Al(OH)_3$ film was formed on the Al substrate, and its chemical state and crystal structure were confirmed by XPS and TEM. According to the results of the XPS analysis, the flake-like morphology after the alkali surface modification was mainly composed of $Al(OH)_3$, with a small amount of $Al_2O_3$. The mesoporous $Al(OH)_3$ layer was composed of three regions: an amorphousrich region, a region of mixed amorphous and crystal domains, and a crystalline-rich region near the $Al(OH)_3$ layer surface. It was confirmed that the stabilization process in the alkali surface modification strongly influenced the crystallization of the mesoporous $Al(OH)_3$ layer.

Design and Implementation of eRTOS Real-time Operating Systems for Wearable Computers (웨어러블 컴퓨터를 위한 저전력 실시간 운영체제 eRTOS 설계 및 구현)

  • Cho, Moon-Haeng;Choi, Chan-Woo;Lee, Cheol-Hoon
    • The Journal of the Korea Contents Association
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    • v.8 no.9
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    • pp.42-54
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    • 2008
  • In recent years, embedded systems have been expanding their application domains from traditional embedded systems such as military weapons, robots, satellites and digital convergence systems such as celluar phones, PMP(Portable Multimedia Player), PDAs(Personal Digital Assistants) to Next Generation Personal Computers(NGPCs) such as eating PCs, wearable computers. The NGPCs are network-based, human-centric digital information devices diverged from the traditional PCs used mainly for document writing, internet searching and database management. Wearable computers with battery capacity and memory size limitations have to use real-time operating systems with small footprints and low power management techniques to provide user's QoS in spite of hardware constraints. In this paper, we have designed and implemented a low-power RTOS (called eRTOS) for wearable computers. The implemented eRTOS has 18KB footprints and the dynamic power management and the device power management schemes are adapted in it. Experimental results with wearable computer applications show that the low power techniques could save energy up to 47 %.

Trend and Implication of OECD Hospital Performance Project (OECD 병원 성과 프로젝트의 동향과 국내 시사점)

  • Park, Choon-Seon;Choi, HyoJung;Hwang, Soo-Hee;Im, JeeHye;Kim, Kyoung-Hoon;Kim, Sun-Min
    • Quality Improvement in Health Care
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    • v.22 no.1
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    • pp.11-26
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    • 2016
  • The Organization for Economic Cooperation and Development, which has continuously evaluated the performance of healthcare systems, has recently invested much effort into hospital performance measurement. The purpose of this paper is to introduce the hospital performance measurement programs operated by international organizations or at the national level based on the OECD's hospital performance project. Health Insurance Review & Assessment service (HIRA)'s quality assessment was analyzed based on the analytical framework of the OECD's hospital performance project. The hospital performance measurement programs of WHO, Canada, Australia, United States and United Kingdom are briefly explored, in view of the conceptual framework, key performance dimensions and indicators that are currently in use. The OECD suggested seven key dimensions of hospital performance: timeliness, efficiency, continuity, effectiveness and appropriateness, staff orientation, patient orientation and safety. The analysis of the quality assessment program of HIRA, which operates 36 diseases and procedures and 347 indicators, shows that the numbers of indicators are relatively small in the areas of safety, patient centeredness and efficiency. Continuity of care and staff orientation are not fully developed also, but the situations are similar in other countries. In conclusion, hospital performance measurement using stable and comprehensive data should be developed to improve overall system performance, and discussions on a conceptual framework that can lay out directions and key performance domains need to take into place.

A Evaluation on the Field Application of Ductile Fiber Reinforced Cement Composites (고인성 섬유보강 시멘트 복합체의 현장 적용성 평가)

  • Ryu, Gum-Sung;Koh, Kyung-Taek;Park, Jung-Jun;Kang, Su-Tae;Kim, Sung-Wook;Park, Sung-Yong
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.04a
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    • pp.941-944
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    • 2008
  • Various ductile fiber reinforced cement composite(DFRCC) including large quantities of PVA fiber or steel fiber have been developed recently and studies to find applications in diverse domains are currently conducted actively. Regard to economical efficiency, DFRCC becomes competitive when applied as special elements and repair material with small quantities rather than the casting of large volume for the main body of structures in field. The authors have developed FRP-DFRCC composite slab for bridges and a wet spraying repair technique using DFRCC. In case of the application on FRP-DFRCC composite slab, it was found that there was no problems the structure and durability of it after passed 3 months. And in case of the application on the application of the deteriorated sewage box that passed 20 years, it was found that there was no difference the repair performance between domestic PVA fiber and the Japan. Therefore, DFRCC using PVA fiber, the concrete structures can be increased to performance and secured the economical efficiency.

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Coexistence of Closely Packed c(4 × 2) and Striped Phases in Self-Assembled Monolayers of Decylthiocyanates on Au(111)

  • Choi, Young-Sik;Kang, Hun-Gu;Choi, In-Chang;Lee, Nam-Suk;Cho, Jun-Hyung;Jang, Chang-Hyun;Noh, Jaeg-Eun
    • Bulletin of the Korean Chemical Society
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    • v.31 no.4
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    • pp.901-904
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    • 2010
  • Decylthiocyanate (DTC) self-assembled monolayers (SAMs) on Au(111) were prepared by solution and vapor phase deposition methods at $50^{\circ}C$ for 24 h. The formation and surface structure of DTC SAMs were examined using scanning tunneling microscopy (STM). STM imaging revealed that DTC SAMs formed in 1 mM ethanol solution at $50^{\circ}C$ were composed of small ordered domains with lateral dimensions of a few nanometers and disordered phases, whereas DTC SAMs formed in the vapor phase at $50^{\circ}C$ contained two ordered phases: a closely packed c($4{\times}2$) superlattice and a striped phase with an interstripe spacing of 2.6 - 2.8 nm. It was also found that the ordered domain and vacancy island formation for DTC SAMs on Au(111) differs significantly from that of decanethiol SAMs, suggesting that adsorption mechanism is different from each other. From this study, it was confirmed that DTC SAMs with a high degree of structural order can be obtained by vapor phase deposition.

Mitoxantrone Binds to Nopp140, an Intrinsically Unstructured Protein, and Modulate its Interaction with Protein Kinase CK2

  • Lee, Won-Kyu;Lee, Sang-Yeop;Na, Jung-Hyun;Jang, Sung-Woo;Park, Chan-Ryang;Kim, Soo-Youl;Lee, Si-Hyeong;Han, Kyou-Hoon;Yu, Yeon-Gyu
    • Bulletin of the Korean Chemical Society
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    • v.33 no.6
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    • pp.2005-2011
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    • 2012
  • Nopp140 is a highly phosphorylated protein that resides in the nucleolus of mammalian cell and is involved in the biogenesis of the nucleolus. It interacts with a variety of proteins related to the synthesis and assembly of the ribosome. It also can bind to a ubiquitous protein kinase CK2 that mediates cell growth and prevents apoptosis. We found that Nopp140 is an intrinsically unfolded protein (IUP) lacking stable secondary structures over its entire sequence of 709 residues. We discovered that mitoxantrone, an anticancer agent, was able to enhance the interaction between Nopp140 and CK2 and maintain suppressed activity of CK2. Surface plasma resonance studies on different domains of Nopp140 show that the C-terminal region of Nopp140 is responsible for binding with mitoxantrone. Our results present an interesting example where a small chemical compound binds to an intrinsically unfolded protein (IUP) and enhances protein-protein interactions.