• Title/Summary/Keyword: Skin tests

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Study on Skin Care Properties of Milk Kefir Whey

  • Chen, Ming-Ju;Liu, J.R.;Sheu, J.F.;Lin, C.W.;Chuang, C.L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.6
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    • pp.905-908
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    • 2006
  • The purpose of this research was to study the effects of kefir whey (kefir whey, peptides, lactic acid) on skin care properties including skin lightening effect and acne treatment. The final aim was to develop a new cosmetic product and enhance the value of dairy products. The results of skin lightening tests showed that all three kefir whey components (kefir whey, peptides and lactic acid) had inhibitory ability against melanin synthesis. Furthermore, copper chelating analysis demonstrated that both kefir whey and kefir whey peptides could chelate the copper in tyrosinase, which might explain the mechanism of inhibition. The ability for acne treatment indicated that lactic acid level higher than 60 mg/ml could inhibit the growth of Propionibacterium acne, whereas no inhibition was found with other components.

A Study on the Errors in Skin Friction Measurements due to Surface Temperature Mismatch (표면온도 차이에 의한 표면마찰력 측정 오차에 대한 연구)

  • 백승욱
    • Journal of the Korea Institute of Military Science and Technology
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    • v.3 no.2
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    • pp.213-218
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    • 2000
  • An experimental study was performed to investigate the effect of surface temperature mismatch on measurements of skin friction using a plug-type skin friction gage mounted on the side wall of a supersonic wind tunnel. The freestream Mach number was 2.4 and Reynolds number per meter was $5.25 {\times}10^7$ with total pressure of 50 psi and total temperature of 275K. Temperature mismatch between the gage surface and surrounding wall surface was generated by hot water injection using the active temperature control system. Results of the tests showed that the temperature mismatch made sizable effects on the measurements of skin friction.

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The study of irritation and toxicity of Carthami oil aquapuncture solution applied topically to the skin and the eye mucous membrane (홍화자약침(紅花子藥鍼)의 피부자극시험 및 안점막자극시험)

  • Lim, Sa-Bi-Na;Kang, Dong-Chul
    • Journal of Pharmacopuncture
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    • v.3 no.1
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    • pp.53-63
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    • 2000
  • Carthami tinctorii Fructus is known for its good effect on diseases such as fracture, menorrhalgia, menoschesis, puerperium aneilema and so on. The study of irritation and toxicity of Carthami oil aquapuncture solution applied topically to the skin and the eye mucous membrane were carried out to prove the safety of Carthami oil aquapuncture solution in clinical use. Animal for the research was the rabbit and the solution for the test was made from Carthami semen. 6 animals were used for the skin test and 9 animals were used for the eye mucous membrane test. In results, both tests proved that Carthami oil aquapuncture solution makes no irritable reaction on skin and eye mucous membrane of rabbit. We consider that this result is helpful for saying about the safety of Carthami oil aquapuncture solution in clinical use.

Drug eruption by antihistamine mistaken for chronic urticaria in a child

  • Lee, Gun Moo;Chu, Shou-Yu;Kang, Sung Yeon;Kim, Hyo-Bin;Park, Jin-Sung;Kim, Ja Kyoung
    • Clinical and Experimental Pediatrics
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    • v.62 no.2
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    • pp.75-78
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    • 2019
  • Although rare, antihistamines can cause adverse effects, including drug-induced eruptions or anaphylaxis. A 4-year-old child visited the pediatric department of a hospital for skin eruptions after administration of antihistamines, (e.g., ucerax [hydroxyzine] or leptizine [levocetirizine]), for cholinergic rashes; he did not have pruritus. Skin prick, intradermal, and drug provocation tests were performed to determine the relationship between the antihistamines and eruptions. Levocetirizine induced wheals in the skin prick test and a rash in the oral drug provocation test. In contrast, ketotifen induced no reaction in the skin prick test but showed a positive reaction in the oral provocation test. Our case report highlights that children can experience the same types of adverse reactions as seen in adults, and cross-reactivity between various antihistamines can occur.

Mural folliculitis and alopecia caused by infection with malignant catarrhal fever virus in goat (Capra hircus) (Malignant catarrhal fever virus 감염과 관련된 goat (Capra hircus)의 mural folliculitis와 alopecia)

  • Kim, Ok-Jin;Crawford, Timothy B.
    • Korean Journal of Veterinary Pathology
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    • v.7 no.1
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    • pp.5-9
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    • 2003
  • Malignant catarrhal fever (MCF) is a systemic disease of ruminants caused by a gamma herpesvirus, ovine herpesvirus 2 (OvHV-2). Four 1-year old goats (Capra hircus), which were infected with MCF virus, OvHV-2, by being housed together with MCF virus-infected seep, were referred with a I-month history of chronic dermatitis. On the other hand, MCF virus-negative goats, which were isolated for negative control, had not those kinds of skin problems. Examination of the affected goats revealed generalized alopecia, patchy erythema, and superficial erosions with histologic evidence of mural folliculitis. Fungal culture tests and external parasite tests with the scraping skin samples were negative. However, polymerase chain reaction revealed the existence of MCF virus DNAs in the lesion. These results suggested that MCF virus may induce mural folliculitis and alopecia in goat.

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Evaluation of particulate removal in slow sand filtration processes (완속여과 공정에서 전처리 공정 도입에 따른 입자제거 효율평가)

  • Kim, Seong-Su;Bae, Chul-Ho;Park, No-Suk;Kang, Suk-Hyung
    • Journal of Korean Society of Water and Wastewater
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    • v.22 no.4
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    • pp.461-466
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    • 2008
  • Because of their simplicity, efficiency, and economy, slow sand filters are appropriate means of water treatment for small water systems. In this study, the effect of filtration velocity and dirty skin (Schmutzdecke) was evaluated on the performance of turbidity removal. Also, removal characteristics of particulate were investigated in the case of the usage of non-woven fabric on the surface of sand and the application of PCF as pretreatment process. Comparative column tests were carried out for the various operation condition. From the result of column tests, filtration velocity had little effect on the turbidity removal rate. The formation of algal biofilm on the surface of media is helpful in turbidity removal, while non-woven fabric is not as effective as expected. The relative contribution of biomass and accumulated particulates to head loss development in slow sand filters requires further study.

A Study on Increase of Bearing Capacity of Dense Sandy Ground installed by Vertical Micropiles (연직 마이크로파일이 설치된 조밀한 모레지반의 지지력 증가에 관한 연구)

  • 최상민;임종철;이태형;공영주
    • Proceedings of the Korean Geotechical Society Conference
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    • 2001.03a
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    • pp.355-362
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    • 2001
  • Since micropiles were conceived in Italy in the early 1950s, which have been widely used for In-situ reinforcement, bearing pile or the concept of combination in the world-wide. The meaning of micropiles usually differs from that of a general deep foundation. Because the load capacity of it was mainly affected by skin friction. Also, it could be obtained the improvement effects of load capacity or ground's rigidity by the unitary behavior of ground and micropiles. In this study, The model tests were peformed on the dense sand where micropiles are set to the vertical direction. Strip footing was used in it. Steel bars of dia. 2 and 4㎜ were used in model tests of which the sand was attached on the surface, and the length of it was changed as 2B to 6B(where, B is width of strip footing) Through this process, the load capacity were analyzed from the test results in the relationship between load and displacement.

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Skin Permeability of piroxicam Gel by Phonophoretic Transdermal Drug Delivery (음파영동 경피약물수송에 의한 Piroxicam Gel의 경피투과)

  • Choi Suk-Joo;Oh Myung-Hwa;Kim Tae-Youl
    • The Journal of Korean Physical Therapy
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    • v.14 no.4
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    • pp.147-162
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    • 2002
  • Transdermal permeation enhancer has been used to increased skin absorption. External control of drug release and skin absorption can also be achieved by iontophoresis or phonophoresis. However, because several problems with iontophoresis are that it has a risk to skin damage because of the change of pH and the increase of current density in applying it and that it can be applied only in the form of water solution, This study is to enhance drug permeation via skin following application of ultrasound. For this goal, in gel containing piroxicam, the degree of skin permeation in vitro and anti-inflammatory effect in in vivo were investigated. Permeation study using hairless mouse skin was performed at 37 $^{\circ}C$ using buffer saline as the receptor solution. The amount of piroxicam were quantified using a HPLC system consisting of solvent delivery system. Following adoption of ultrasound 1 MHZ, it showed relatively high permeation rate where it was compared with non treated by ultrasound. The influence of duty cycle having an effect on skin permeation rate was slight higher in the case of using pulsed mode. Skin permeation increase attended by intensity of ultrasound, the permeation of trice was accelerated at 2.0 W/$cm^{2}$ than 1.0 W/$cm^{2}$. The skin permeation of piroxicam was substantially influenced by ultrasound. Anti-inflammatory effects were determined using carrageenan-induced paw swelling method in SD rat. Paw swelling tests showed that pulsed phonophoresis group was more effective than control group and only gel application group. The conclusion of phonophoresis was found to improve significantly the skin permeation in vitro and the anti-inflammatory effect in vivo.

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Structure and Cytochemistry of Skin in Spined Loach, Iksookimia longicorpus (Pisces, Cobitidae) (왕종개 Iksookimia longicorpus (Pisces, Cobitidae) 피부 구조와 세포화학적 특징)

  • Park, Jong-Young;Kim, Ik-Soo
    • Korean Journal of Ichthyology
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    • v.12 no.1
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    • pp.25-32
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    • 2000
  • The structure of skin was studied in Iksookimia longicorpus based on the micro-anatomical investigation of skin fragments taken from four regions. The epidermis was distinguished by two types of skin glands, a small mucous cell and a large club cell. The mucous cell was acid sulfomucins (some sialomueins) but the club cell did not give any histochemical tests for mucosubstances. The presence of a well defined lymphatic system with small lymphocytes was established in the stratum germinativum layer of the epidermis. A large number of blood capillaries run very close to each other just below the basement membrane, and a definite area giving AB and PAS positive was present between the basement membrane and scale.

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Antimicrobial Susceptibility Patterns of Staphylococcus intermedius Isolated from Skin Lesions of Thoroughbred Horse. (더러브렛 말의 피부병변에서 분리한 Staphylococcus intermedius의 약제 감수성 양상)

  • Choi, Seong-Kyoon;Park, Cheong-Kyu;Kwon, Oh-Deog;Cho, Gil-Jae
    • Journal of Life Science
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    • v.18 no.3
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    • pp.369-373
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    • 2008
  • Staphylococcus intermedius (S. intermedius) has been rarely isolated from horse. In this study, we investigated the antimicrobial susceptibility patterns of S. intermedius isolated from skin lesions of Thoroughbred horse in Daegu Equestrian Association. The skin lesions were showed with dehairing and slight purulent inflammation. Bacteria were isolated from skin lesions and identified as S. intermedius by biochemical tests and MicroLog (BIOLOG, California, USA). Antimicrobial susceptibility test of S. intemedius isolates was performed with 33 antimicrobial agents (BBL, Maryland, USA) by using the agar disk diffusion method. It showed a high sensibility in the amikacin, amoxycillin/clavuramic acid, ampicillin, cefoxitin, cephalothin, chloramphenicol, ciprofloxacin, enrofloxacin, florfenicol, kanamycin, neomycin, nitrofurantoin, norfloxacin, ofloxacin, oxacillin, penicillin G, tetracycline and vancomycin. The horse was treated with penicillin, and cured completely after two weeks. The present results showed valuable information for treatment and prevention of skin disease in horse.