• The Korea Journal of Herbology
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• v.37 no.3
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• pp.1-8
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• 2022

Objectives : The purpose of this study was to investigate the efficacy of Abelmoschus manihot (A-M) on the facial skin by observing the changes in the skin caused by continuous use of the essence containing A-M. Methods : Fifty-one participants were enrolled, 38 were classified as experimental group and 13 were classified as control group. Before the beginning of the test, the skin condition of the participants was investigated with the facial analyzer. An essence containing A-M was provided to the experimental group, and an essence base not containing Abelmoschus manihot was provided to the control group. Participants were asked to use the product in the morning and evening after washing their face. We checked the skin change status every 2 weeks and performed the test 3 times for 6 weeks. Results : In the case of t-zone oil and pores, there was a significant decrease in the experimental group. In the case of moisture, a significant increase was observed in the control group, but the significance was significantly increased when the essence containing A-M was used. In the case of elasticity, it was found that the experimental group continued to increase with the period of use. Conclusion : It is thought that the essence containing A-M will be effective in preventing skin aging through the reduction of t-zone oil, the size of the pores, and the increase in moisture and elasticity.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.3
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• pp.88-96
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• 2012

Objectives : We investigated the skin properties on the periorbital region and cheek of Korean female according to age pattern by 7year based on Sang Go Cheun Jin Ron (上古天眞論) in So Moon (素問,) Methods : 49 Korean females, aged 21-56 years ($39.54{\pm}10.04$ years) were participated in this study. We measured the skin properties of periorbital region and cheek with SkinTouch (Amorepacific, Korea). Skin moisture, sebum, elasticity, lightness, roughness, area of wrinkle, depth of wrinkle were assessed. Results : Differences were noticed depending on the site and age. The level of moisture was higher on the eyelid than crow's feet. The level of lightness and elasticity were lower on the periorbital region than cheek. Skin lightness was highest on group1(under 28y) and lowest on group5(over 49y). Skin roughness was highest on group1(under 28y) and lowest on group4(over 42y under 49y). The level of wrinkle are was lowest on group1(under 28y) and highest on group 5(over49y). The level of wrinkle depth was lowest on group1(under 28y) and highest on group 4(over 42y under 49y). Conclusion : Unique aging pattern by 7 years of female is reflected to diverse skin properties of eyes. It can be possible to apply the theory on Sang Go Cheun Jin Ron (上古天眞論) to practical use in dermatology and cosmetic.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.4
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• pp.264-274
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• 2019

This study attempted to analyze the effects of cleansing oil on skin by preferred vegetable base oil. For this, a questionnaire survey was performed against 100 people, and their face washing habit and preferred vegetable base oils were examined. Based on the results, 4 different cleansing oils were prepared and experimented. The experiment was conducted against 10 adult women in their 20-30s, and moisture level, sebum level and trans-epidermal water loss (TEWL) before and after the experiment were measured. After the test, satisfaction was measured, and the results found the followings: When asked what cleansing oil is most preferred by vegetable base oil type, 'rose hip oil' was the highest, followed by 'olive oil', 'apricot kernel oil' and 'camellia oil'. According to the clinical trials, both moisture and sebum levels increased before and after cleansing in all four cleansing oil types by the preferred vegetable base oil (p<0.001, p<0.001). In addition, TEWL decreased with a difference by base oil (p<0.01). According to a subjective satisfaction survey which was performed after the experiment, rose hip oil-contained cleansing oil (RHC) was the highest in terms of cleansing effect and satisfaction level. Consequently, it was confirmed that the cleansing oil by vegetable base oil improved skin conditions by protecting a skin barrier with a positive effect on the improvement of sebum and moisture levels and TEWL. Even though a preferred oil type and a satisfaction level may differ by preferred oil and feeling after use, cleansing oil by vegetable base can be helpful as a skin care product which eases skin dryness and protects a skin barrier.

• Journal of the Korean Applied Science and Technology
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• v.36 no.4
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• pp.1219-1223
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• 2019

The skin condition varies by the parts of the face. This study intended to visualize the facial skin based on the characteristics including moisture, sebum, dryness, amount of dead skin cells, and roughness by sectionalizing the facial skin into 9 areas. A total of 98 female in their 20~35s were selected, and the characteristics of skin by area were selected and listed in the order, and the area they felt each characteristic most strongly was analyzed with a weight and the result was visualized. The result showed that the area where they felt dryness the most was around the lips and eyes, and the area where the largest amount of dead skin cells and rough skin existed was the chin. There was a significant increase in moisture content (p <.05), and 90.5% of satisfaction with dryness was satisfied. The result of this study will be used as a basic data for the development of a cosmetic mask pack or a functional cosmetic product for each part.

• Journal of Pharmaceutical Investigation
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• v.36 no.6
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• pp.393-399
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• 2006

This study was aimed to design, formulate and characterize the moisture-activated patches containing acyclovir for antiviral action. Gel intermediates for film-type patches were prepared with mucoadhesive polymer, viscosity builders, enhancers and acyclovir. Patches containing acyclovir were characterized by in vitro measurement of drug release rates through a cellulose barrier membrane, and of drug flux through the hairless mouse skin. Film-type patches obtained were uniform in the thickness and showed a mucoadhesive property when contacted with moisture. The formulation was optimized, which consisted of $Cantrez^{\circledR}$ AN-169(2%), $Kollidon^{\circledR}$ VA 64(1%), $Natrosol^{\circledR}$(1%), hydroxypropyl-$\beta$-cyclodextrin(1%) and dimethylsulfoxide(0.5%). Release rates of acyclovir patches increased dose-dependently. The addition of terpenes such as d-limonene or cineole increased release rates of acyclovir, but decreased permeation rates. The permeation rates were enhanced by 2 and 2.5 times by the addition of glycyrrhizic acid ammonium salt and sodium glycocholate, respectively, compared with that of no enhancer. These results suggest that it may be feasible to deliver acyclovir through the skin or gingival mucosa from the moisture-activated patches.

• The Korea Journal of Herbology
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• v.38 no.2
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• pp.35-41
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• 2023

Objectives : Washing face is the first step in skin beauty and health. I wanted to study the cleansing effect by using Placenta cp (cold process) soap. The skin condition is greatly influenced by the external environment such as lifestyle, drinking, smoking, and stress etc. I tried to measure the skin change state without environmental factors. Methods : In order to examine the effect before and after washing face under the same conditions, the same water and towel were used in the same place. The skin test was performed before and 10 minutes after washing. As a control group, a case of washing with water and foam cleanser. I compared and analyzed three cases: water washing, F/C (foam cleanser) washing, and Placenta cp soap washing. Results : In the case of water washing, it was significantly reduced in pores and increased in facial temperature. In the case of F/C washing, the facial temperature was significantly increased, but the decrease in moisture. In the case of washing with Placenta cp soap, significant reductions in T-zone and U-zone oil content, reduction in pore size, and increase in facial skin temperature were observed. Conclusion : In the case of Placenta cp soap, it is thought to be suitable for oily skin type, because of significant decrease in T-zone and U-zone oil content. It is thought to have the effect of increasing blood circulation in the facial skin and to reduce pores for oily skin types.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.21 no.3
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• pp.124-131
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• 2008

Objectives : The aim of this study was conducted to test dry infant skin by external application with herbs in cosmetics. Methods : A total of 25 infants who visited Daegu Hanny Oriental Medical Center from March 5th, 2008 to May 18th, 2008 were included in this study. In this study, they were treated with the cosmetic products(body wash, rotion, cream) containing herbs. For 4 weaks skin moisture content was measured by corneometer ClVI825. And satisfaction after using body wash, rotion, cream was checked. Results : There were no significant differences on sex and age. Change of skin moisture content between before treatment and after treatment (2, 4 weeks) showed significant changes(p<0.05). Satisfaction after using body wash, rotion, cream was near good. Conclusions : Considering the above results, we have concluded that cosmetics containing herbs have the remarkable effect on infant skin mosturizing.

• Bulletin of the Korean Chemical Society
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• v.28 no.1
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• pp.99-102
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• 2007

To prepare freeze-dried ascorbyl palmitate (AsP)-containing liposome which can protect the drug from moisture attack and be used instantly by mixing with water for anti-aging and skin whitening therapy, AsP was encapsulated into liposomes and freeze-dried with trehalose. The freeze-dried liposome formulations were characterized by measuring water contents, particle size, time required for complete reconstitution. With the freeze-dried liposomes, we performed the stability test under accelerated conditions, skin permeation and localization test. The measurement of the time to perfect reconstitution showed that the freeze-dried liposomes can be changed to their initial state rapidly and short term stability test of AsP in reconstituted liposomes under accelerated conditions confirmed that the stability of AsP was considerably enhanced as compared to freshly prepared liposomes. The skin permeation and localization properties of AsP in reconstituted liposomes were not significantly different, indicating that the liposomal structures were maintained before and after freezedrying. In conclusion, the freeze-drying method provided a possible way to overcome the instability issue of AsP induced by the moisture and reproduced similar skin permeation and localization properties as shown by freshly prepared liposomes.

• Journal of Microbiology and Biotechnology
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• v.27 no.9
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• pp.1657-1663
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• 2017

Cosmetic patches have recently been developed as skin products for personal care owing to rapid advances in the technology of delivery of active ingredients, moisture, and adhesiveness to skin. Alginate and Spirulina are typical marine resources used in cosmetic products. This research involved the development of a Spirulina extract-impregnated alginate nanofiber cosmetic patch supported by a polycaprolactone (PCL) nanofiber cover (Spi/Alg-PCL NF patch). In addition to the ability of alginate to affect moisture and adhesiveness to skin, the impregnation of Spirulina extract strengthened those abilities as well as its own bioactive effectiveness. All fabrication processing steps were undertaken in aqueous solution. The three components (alginate, Spirulina extract, and PCL) had no detected cytotoxicity in human keratinocyte cell-based examination. In addition, wetting the pre-dried patch on the skin resulted in the Spirulina extract being released within 30 min. The results indicate the excellence of the Spi/Alg-PCL NF patch as a skin-care cosmetic device.

• Fibers and Polymers
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• v.4 no.4
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• pp.215-221
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• 2003

A vertical skin model with two detachable environmental chambers was developed to simulate a Human-Clothing-Environment system and to evaluate heat and moisture transport properties of textile materials under severe conditions and during transient states. The construction of the system was described and data reproducibility and accuracy of the instrument were verified by using PEG treated nonwovens. Also advantages over a traditional static type experiment were demonstrated based on a series of experiments.