• Korean Journal of Psychosomatic Medicine
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• v.31 no.1
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• pp.19-24
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• 2023

Objectives : Biofeedback is a useful non-pharmacological treatment for panic disorder (PD), but no studies have identified physiological markers related to the treatment response. This study investigated predictors of the treatment response for biofeedback in patients with PD. Methods : A retrospective study based on the electronic medical records of 372 adult patients with PD was performed. Patients received biofeedback treatment at least once, and physiological markers including heart rate, heart rate variability, respiratory rate, skin conductance, skin temperature, and electromyography were collected before the treatment began. The patients were classified as responders or non-responders based on the change in Clinical Global Impression-Severity (CGI-S) score. Results : The response rate to biofeedback treatment was 30.4%. Multivariable logistic regression analysis revealed that a higher CGI-S score at baseline and fewer benzodiazepine prescriptions were associated with a better response to biofeedback treatment. According to subgroup analyses, the baseline CGI-S score, dose of benzodiazepines, and skin conductance are candidate predictors of the response to biofeedback treatment in men, while only baseline disease severity was associated with the treatment response in women. Conclusions : The present results suggest that skin conductance may be target marker and predictor for biofeedback in male patients with PD.

• Korean Journal of Acupuncture
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• v.26 no.4
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• pp.39-52
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• 2009

Objectives : Cue reactivity is a key factor that modulates motivational goal-directed behavior associated with compulsive drug-taking and relapse. We investigated whether acupuncture attenuated the skin conductance response and the heart rate response to smoking-related visual cues in smokers. Methods : Twenty-nine smokers were treated with real acupuncture (RA) or sham acupuncture (SA). The stress response inventory was measured on the 5th day after quitting smoking. The skin conductance response and the heart rate were measured to evaluate the autonomic changes to the smoking related visual cues on the same day. Results : The sympathetic alterations in skin conductance and the heart rate induced by the smoking-related visual cues were significantly lower in the RA group, as compared to the SA group. The stress response inventory, such as somatization and frustration, in the RA group was significantly lower than that of the SA group. Conclusions : Acupuncture ameliorated the stress symptoms as well as the sympathetic activation to smoking cues during withdrawal. These findings indicate that acupuncture might be a useful tool in smoking cessation by inhibiting smoking cues-induced autonomic responses.

• Science of Emotion and Sensibility
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• v.7 no.3
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• pp.27-35
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• 2004

This study has investigated a psychological status of optimal and pleasant driving condition by measuring various physiological signals using SCR(skin conductance response), PPG(peripheral plethysmograph), SKT(skin temperature) and HR(heart rate). The physiological response was measured during various simulated driving conditions. We developed a hardware and algorithm to measure and analyze the physiological response. The physiological signals has reflected the level of driver's tension or relaxation as well as the heart rate. The emotional responses of drivers were also measured and analyzed in this experiment. The result of the study can be used to design a system to enhance the driver's emotional satisfaction as well as to monitor the driver's safety and health condition.

• The Journal of Korean Academy of Sensory Integration
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• v.9 no.1
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• pp.45-52
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• 2011

Objective : The aim of this study was to provide the method to measure physiologic response using equipments and auditory stimulation, and the physiologic response features of adult psychiatric disorders through a systemic review. Methods : The systemic review was executed using PubMed. The key words for search were "auditory stimulation, auditory startle, electromyograph, skin conductance, heart rate, psychiatric disorder, anxiety disorder, schizophrenia, depression". 8 studies were used for data analysis, and all of levels of evidence were level II. The substances of the review were subject(population), auditory stimulation, measure equipments and physiologic response features of psychiatric disorder. Results : 1. The subjects for the studies were anxiety disorder(4) and schizophrenia(4). 2. Auditory stimulation was used in 8 studies and visual stimulation with auditory stimulation was used in 2 studies to induce physiologic response. 3. Every study used electromyograph, and skin conductance was used in 2 studies and heart rate was used in 2 studies with electromyograph to measure physiologic response. 4. The subjects for the studies, schizophrenia and anxiety disorder(PTSD, OCD) have different physiologic response features with the normal control group. Conclusion : All studies used simple tones as an auditory stimulation and electromyograph to measure physiologic response. Psychiatric disorders indicated larger response, shorter and delayed habituation. The objective and systematic study using physiologic measure to investigate the sensory feature of psychologic disorders.

• The Journal of Korean Physical Therapy
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• v.22 no.1
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• pp.61-66
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• 2010

Purpose: The purpose of this study was to investigate the change in sympathetic nervous system responses of healthy adult women with changes in stimulus intensity of high frequency transcutaneous electrical nerve stimulation. Methods: Twenty-four healthy subjects (women) received high frequency electrical stimulation of the forearm. The subjects were randomly assigned to one of two groups; a low intensity stimulation group (n=12) and a high intensity stimulation group (n=12). The electrode attachment was arranged on the forearm of the dominant arm and the electricity stimulus time was 20 minutes. Measured items included skin conductance, pulse rate, skin temperature, and respiration rate. Each was measured at 4 times. Results: Skin conductance and skin temperature showed significant group by time interactions, though there were no significant group and time effects. There were no significant differences according to time, group effect, and a group by time interaction in pulse and respiration rates. Conclusion: High frequency and high intensity electrical stimulation may be helpful for the improvement of sudomotor function through the activation of the sympathetic nervous system. Also, high frequency and low intensity electrical stimulation may be helpful for the reduction of sudomotor function via inhibition of the sympathetic nervous system.

• Proceedings of the Acoustical Society of Korea Conference
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• 1998.06c
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• pp.291-296
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• 1998

In the experiment carried out on 20 college students, recorded were frontal, temporal and occipital EEG, skin conductance response, skin conductance level, heart rate and respiration rate during listening to two music fragments with different affective valences and white noise administered immediately after negative visual stimulation. Analysis of physiological patterns observed during the experiment suggests that affective auditory stimulation with music is able to selectively modulate autonomic and cortical activity evoked by preceding aversive visual stimulation and to restore initial baseline levels. On other hand, physiological responses to white noise, which does not possess emotion-eliciting capabilities, evokes response typical for orienting reaction after the onset of a stimulus and is rapidly followed by habituation. Observed responses to white noise were similar to those specific to attention only and had no evidence for any emotion-related processes. Interpretation of the obtained data is considered in terms of the role of emotional and orienting significance of stimuli, dependence of effects on the background physiological activation level and time courses of attention and emotion processes. Physiological parameters are summarized with regard to their potential utility in differentiation of psychological processes induced by auditory stimuli.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2002.05a
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• pp.107-113
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• 2002

We examined the psychophysiological effects of navigation in a virtual reality (VR). Subjects were exposed to the VR, and required to detect specific objects. Ten electrophysiological signals were recorded before, during, and after navigation in the VR. Six questionnaires on the VR experience were acquired from 45 healthy subjects. There were significant changes between the VR period and the pre-VR control period in several psychophysiological measurements. During the VR period, eye blink, skin conductance level, and alpha frequency of EEG were decreased but gamma wave were increased. Physiological changes associated with cybersickness included increased heart rate, eye blink, skin conductance response, and gamma wave and decreased photoplethysmogram and skin temperature. These results suggest an attentional change during VR navigation and activation of the autonomic nervous system for cybersickness. These findings would enhance our understanding for the psychophysiological changes during VR navigation and cybersickness.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.8 no.2
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• pp.19-24
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• 2010

Purpose : This study aims to examine the influences of galvanic vestibular stimulation on autonomic reaction of normal adults. Methods : Participants in this research totaled 28 (14 men and 14 women). Galvanic vestibular stimulation was conducted with a binaural electrode configuration for 60 sec. Galvanic vestibular stimulation measurements were conducted with the subjects in a prone position. Measured items included skin conductance, blood flow, pulse rate, and respiratory rate. Measurements were repeated for a total of five times, before application, during application, after application, 5 minutes after application and 10 minutes after application. Results : Skin conductance reaction showed statistically significant differences in changes depending on time after galvanic vestibular stimulation and there were statistically differences in changes of blood flow, pulse rate and respiratory rate after galvanic vestibular stimulation. Conclusion : Blood flow, pulse rate and respiratory rate of autonomic reactions were not influenced by galvanic vestibular stimulation, but skin conductance reaction was influenced by it and it was found that it was reduced during and after stimulation rather than before stimulation. Consequently, it was considered that galvanic vestibular stimulation affected the autonomic reaction.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.269-273
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• 1999

Combination of mental stress task with noise background is a traditional tool employed in psychophysiology. However, intensity of background noise is a factor affecting both performance on test and psychophysiological responses associated with stress evoked by mental load in noisy environment. In the current study on 7 subjects we analyzed the influence of white noise (WN) intensity (55, 70, and 85 dB[A] ) on psychophysiological responses during word recognition test performed on noise background. There were recorded following physiological variables: electrodermal activity (EDA) , namely, skin conductance level (SCL), skin conductance response (SCR) amplitude (SCR-A), rise time and total number of SCRs (N-SCR); cardiovascular activity, e.g., heart rate (HR), respiratory sinus arrhythmia (RSA) index, pulse transit time (PTT), finger pulse volume (PV), skin temperature (SKT) and respiratory activity, such as respiration rate (RESP-R) and inspiration wane amplitude (RESP-A) during baseline resting state and 40 s long performance on 3 similar Korean word recognition tests with different WN intensity (55, 70, and 85 dB). Electrodermal responses (SCR-A, SCL, N-SCR) demonstrated gradual increment with increased intensity of noise, and this increase of response magnitude with higher intensity of noise was typical also for r skin temperature (phasic SKT decrease) and pulse volume (phasic and tonic PV decrease). However, some cardiovascular and respiratory responses did not exhibit same tendency of gradual increase of reactivity , namely HR, as well as RESP-R and RESP-A showed decrement of response magnitudes. Important finding in terms of cardiovascular reactivity was that 55 and 70dB evoked similar profiles, while 85dB WN resulted in significantly different profile of reactions, suggesting that there exists a threshold level after which intensive auditory stimulation elicits psychophyslological responses pattern of different quality. There are discussed potential autonomic mechanism involved in mediation of observed physiological responses.

• Proceedings of the KOSOMBE Conference
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• v.1992 no.11
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• pp.51-54
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• 1992

In this paper, we quantitatively evaluated the anxiety data from humans in an anxiety state. It has been reported that the electric signals of human can be correlated with their emotional state. We chose heart rate, respiration rate, temperature and skin conductance as the anxiety parameters. For experiment protocol, the subject was given exercising load to induce the anxiety state and the exercise was done using the FITRON Cycle Ergometer. We divided the data into three stages: rest period, exercise period, and recovery period. During evaluation, We counted the heart rate, slope of heart rate, temperature change, and the skin conductance.