• International Journal of Korean Welding Society
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• 제5권1호
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• pp.29-34
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• 2005

Finite element analysis (FEA) and experimental studies on an elastic bending method have been performed in order to control the angular distortion at the fillet weldment for curved panel. Process parameters for the elastic bending method such as clamping span and release time were analyzed with reference to welding condition and geometric effect of the curved panel, which can minimize or prevent the angular distortion by producing a proper skin stress to the fillet weldment. The amounts of the angular distortion decrease almost in a linear manner with an increase in the skin stress. The skin stress required for non-angular distortion at the fillet weldment is strongly dependent on the plate thickness, not the heat intensity applied. The clamping span for obtaining uniform skin stress was defined as functions of the plate thickness and length of the free edge. Clamp should be removed after the fillet weldment is cooled down to room temperature for non-angular distortion. Effectiveness of the elastic bending method established was verified by its application to an actual curved panel.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1999년도 하계종합학술대회 논문집
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• pp.575-578
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• 1999

The principal features of a face are as follows : skin-tone, symmetry, and requisites such as shape of ellipse, eyes, nose, mouth. Also, faces have different size, various shape and position. In case of application of face recognition and detection without preprocessing, efficiency of the performance is decreased. In addition, face itself, complex background, image quality, etc. are included. Therefore, previous face recognition methods are implemented on the base of specific constraints of the face image. In this paper, we propose the efficient and automatic face detection algorithm for minimizing influence such as complex background, image quality, etc. This face detection technique consists of skin-tone, candidate face region and face region extractions.

• KIEAE Journal
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• 제13권1호
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• pp.75-81
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• 2013

The balcony of our apartment building consists of unique construction similar to double skin. It is announced broadly that double skin is very effective system in improvement of natural ventilation and indoor thermal environment, and outdoor sound protection. So, for the improvement of indoor climate and energy saving, many peoples studied about environmental performance of our balcony construction. This study focus on shaft box facade, special form of box window construction. It consists of a system of box window with continuous vertical shafts that extend over a number of stories to create a stack effect. Proto-type was decided by analyzing various types of exiting apartments. Shaft box type balcony was created by setting up shaft space at a part of balcony. Air flow and contribution of air temperature were simulated, performance of shaft box type balcony was compared with existing balcony. Finally, we confirmed that shaft box type balcony has many possibility for improvement of indoor environment.

• 대한한방소아과학회지
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• 제17권2호
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• pp.85-101
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• 2003

Objectives : The purpose of this study was the collection of dietary and external treatments of atopic dermatitis and it's classification according to physical type. Methods : The author conducted a literature and Internet search in data. Results : We collected the generally used dietary and external treatments. These collected treatments are classified according to the following oriental medical categories; thermic and wet skin type, thermic and dry skin type, chill and wet skin type and chill and dry skin type. conclusion : Wemust use these treatments pertinently according to physical type.

• Genomics & Informatics
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• 제21권3호
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• pp.43.1-43.13
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• 2023

Melanin is synthesized by tyrosinase to protect the skin from ultraviolet light. However, overproduction and accumulation of melanin can result in hyperpigmentation and skin melanoma. Tyrosinase inhibitors are commonly used in the treatment of hyperpigmentation. Natural tyrosinase inhibitors are often favoured over synthetic ones due to the potential side effects of the latter, which can include skin irritation, allergies, and other adverse reactions. Nuciferine, an alkaloid derived from Nelumbo nucifera, exhibits potent antioxidant and anti-proliferative properties. This study focused on the in silico screening of nuciferine for anti-tyrosinase activity, using kojic acid, ascorbic acid, and resorcinol as standards. The tyrosinase protein target was selected through homology modeling. The residues of the substrate binding pocket and active site pockets were identified for the purposes of grid box optimization and docking. Therefore, nuciferine is a potent natural tyrosinase inhibitor and shows promising potential for application in the treatment of hyperpigmentation and skin melanoma.

• 한방안이비인후피부과학회지
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• 제37권1호
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• pp.86-96
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• 2024

Objectives : The aim of this study is to report a case showing rapid skin regeneration and recovery by applying Korean medicine treatment to lower extremity ulcer. Methods : We treated a female patient with idiopathic right leg ulcer by Korean medicine treatment such as herbal medicine, acupuncture, pharmacopuncture, Coptidis Rhizoma distillate wet dressing, and Jawoongo application. The treatment effect was evaluated by visual observation through photography, measurement of the area of the affected area, NRS(Numeral Rating Scale) for the level of discomfort, DLQI(Dermatology life quality index), and treatment satisfaction. Results : After Korean medicine treatment, recovery of skin tissue, reduction in affected area, and decrease in NRS for discomfort and DLQI were observed, and satisfaction with Korean medicine treatment was also high at 80%. Conclusions : This study shows that Korean medicine treatment can be effective in treating skin ulcers. We hope that research of Korean medicine treatment on skin ulcers will be promoted in the future.

• 동의생리병리학회지
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• 제23권3호
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• pp.619-630
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• 2009

To investigate the hair growth activity of fractions and extract of Arisaematis Rhizoma in the hair removed skin of normal and spontaneous alopecia areata model in C57B/6N mice. These experiments were performed with the macroscopic, microscopic, immunohistochemical(VEGF, c-kit, PKC-${\alpha}$, TGF and FGF) and RT-PCR(TGF-${\beta}$, IGF, prolactin and placenta lactogen) methods. The results were as follows: Macroscopic observation after topical application of vehicle, 50% EtOH as control and extract of Arisaematis Rhizoma to the hair removed skin of C57BL/6N mice on the 9th, 11th and 15th day. Extensive hair growth activity was observed in treated group with extract of Arisaematis Rhizoma on the 9th, 11th and 15th day. In Arisaematis Rhizoma extracts treated group, hair follicles of middle stage of anagen was observed and it were grown down to subcutaneous tissue of skin in all the normal mice on 15th day. But in control group, most of hair follicles of telogen phase was observed in skin. The treatment of extract of Arisaematis Rhizoma increased expression of IGF(145%) and placenta lactogen(108%) in the skin of normal C57BL/6N mice on the 11th day compared to control group(100%). But expression of TGF-${\beta}$(90%) and prolactin(91%) decreased in the skin of normal C57B/6N mice on the 11th day compared to control group(100%). After application of fractions(chloroform, ethyl acetate and water fractions) of Arisaematis Rhizoma extract for 9th day, hair growth effect was observed in whole skin area in 50% of normal mice. But in control group, hair growth effect was not observed in whole skin area of normal mice. Immunoreactive density of VEGF, c-kit, PKC-${\alpha$ and FGF in skin of fractions of Arisaematis Rhizoma extracts was strongly stained in epidermis, bulge, secondary hair germ cells, cutaneous trunci m., subcutaneous tissue, root sheath compare to control group on the 9th day. In spontaneous alopecia areata model, The hair growth activity of Arisaematis Rhizoma extrat treated group(75%) was observed to be strong compared to control group(O%) on 7th day. These experiments suggest that fractions and extracts of Arisaematis Rhizoma may stimulate the topical hair growth activity. Thus it can be useful for treatment of alopecia areata.

• Applied Microscopy
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• 제38권1호
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• pp.35-41
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• 2008

본 연구의 목적은 양파 외피를 분상의 상태로 제조하여 모발염색의 최적에 조건을 규명하기 위해 V.H.에 4회 탈색 (B.H.)하여 시험모를 제작한 후 양파 외피 추출물을 시간, 온도, 농도, pH, 매염제 처리별로 조건을 달리하여 모발의 염색성과 기계적 형태학적 변화를 관찰하였다. 모발 표면을 주사전자현미경을 통해 관찰한 결과 모표피층이 완전 용해된 B.H.에 비해 양파 외피 추출물로 염색한 모발에 경우 약간 들떠있는 상태는 보이지만 모표피층이 형성되어 있는 것을 관찰할 수 있었다. 이와 같은 연구의 결과로부터 양파 외피에서 추출한 천연 색소는 분상의 염모제로 제조 시 대량 생산과 보관에 있어 효과적으로 실용화가 충분히 가능하다고 사료된다.

• Environmental Analysis Health and Toxicology
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• 제11권1_2호
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• pp.1-10
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• 1996

A decrease in stratospheric ozone probably caused by chloroflurocarbons (CFCs) emissions, has been observed large parts of-the globe. It is generally accepted that if ozone levels in the stratosphere are depleted, greater amounts of shortwave ultraviolet radiationB (UVB) will reach the earth's surface, resulting in increased incidence of nonmelanoma skin cancer. In this study, we evaluated several mathematical models, such as a power and an exponential model, and a geometric model considering the surface area of a human body part and ages for the prediction of Skin cancer incidence caused by exposure to the UVB radiation. These models basically estimated the risk of skin cancer based on those measurements of the local ozone in stratosphere and UVB. Both were measured at a part of Seoul with a Dobson ozone spectrometer and Robertson-Berger UV Biometer for 1995. As a result, we calculated the point estimation applying a biological amplification factor (BAF), UVB radiation and other factors. We used a Monte-Carlo simulation technique with assumption on the distribution of each considered factor. The sensitivity analysis of model by there components conducted using Gaussian sensitivity method. The annual integral of UVB radiation was 2275 MED (minimal erythema dose)/yr. Also, an estimate of the annual amount of UVB reaching the earth's surface at a korea's latitude and altitude was 3328 MED/yr. The values of the radiation amplification factor (RAF) were ranged from 0.9 to 1.5 in Seoul. To give the effective factors required to model the prediction of skin cancer incidence caused by exposure to the UVB radiation in Korea, we studied the pros and cons of above mentioned models with the application of those parameters measured in Seoul, Korea.

• Medical Lasers
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• 제10권2호
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• pp.96-105
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• 2021

Background and Objectives Skin aging is reportedly associated with regulation in collagen and elastin synthesis. This study investigated the potential of combining light-emitting diode (LED) treatments using a 630-nm and 850-nm LED with simultaneous microcurrent application. Materials and Methods The dorsal skin of female pigs was treated with a home-use device. We examined the treatment effects using photography, thermocamera, microscopic pathology, and histological examination to determine the mechanism of action, efficacy, and safety of the procedure. A histological observation was performed using hematoxylin and eosin, Masson's trichrome, Victoria blue, and immunohistochemical staining. We also used the Sircol soluble collagen and elastin assay kit to measure the amounts of collagen and elastin in the porcine back skin tissue after 2 and 6 weeks. Results Evaluation by visual inspection and devices showed no skin damage or heat-induced injury at the treatment site. Histological staining revealed that accurate treatment of the targeted dermis layer effectively enhanced collagen and elastin deposition. Collagen type I, a protein defined by immunohistochemical staining, was overexpressed in the early stages of weeks 2 and 6. Combined therapy findings showed the superior capability of the 630-nm and 850-nm LED procedures to induce collagen; in contrast, elastin induction was more pronounced after microcurrent treatments. Conclusion The home-use LED device, comprising a combination of 630-nm and 850-nm LEDs and microcurrent, is safe and can be used as an adjunctive treatment for self-administered facial rejuvenation.