• Title/Summary/Keyword: Skin/pathology

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A Literature Study On Physiology, Pathology and Clinical Applications for TCM Cosmetology (중의미용(中醫美容)의 생리병리, 임상응용에 관한 문헌고찰)

  • Yang, Mi-Sung;Shin, Mi-Sook
    • Korean Journal of Acupuncture
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    • v.26 no.4
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    • pp.107-118
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    • 2009
  • Objectives : This study was performed to investigate physiology, pathology and clinical applications for cosmetology in Traditional Chinese Medicine. We hope most clinicians practicing cosmetic acupuncture to understand theoretical background well and to treat cosmetic diseases more diversely by this paper. Methods : We collected useful informations from 35 papers in Chinese at website www.cnki.net about TCM treatments including acupuncture, moxibustion and herbal medicine. And we could see important factors connected with physiology, pathology and clinical applications within this field. Conclusions : Liver, lung, stomach, mental disorders and yin-deficiency constitution were connected each other in cosmetic physiology. Blood stasis and congestion were thought highly in cosmetic pathology. In clinical applications, wet cupping therapy on the acupoints located in the back line of Governor Vessel(GV), ear-acupuncture, acupuncture using local facial acupoints, pharmacopuncture, moxibustion were used diversely for each case with cosmetic disorders. Especially, local acupoints and remote acupoints were selected at the same time for wrinkle care. And studies on plastic surgery sequelae, dark skin, acne and melasma were more published than those on wrinkle care.

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Treatment of Distal Tibia Fracture using MIPPO Technique with Locking Compression Plate: Comparative Study of the Intraarticular Fracture and Extraarticular Fracture (잠김-압박 금속판을 사용하여 MIPPO 수기를 적용한 원위부 경골 골절의 치료: 관절내 골절과 관절외 골절의 비교)

  • Chung, Soo-Tae;Kim, Hyung-Soo;Cha, Seung-Do;Yoo, Jeong-Hyun;Park, Jai-Hyung;Kim, Joo-Hak;Jung, Jin-Ha
    • Journal of Korean Foot and Ankle Society
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    • v.13 no.2
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    • pp.162-168
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    • 2009
  • Purpose: To evaluate the efficiency of the minimally invasive percutaneous plate osteosynthesis (MIPPO) with locking compression plate (LCP) for distal tibial metaphyseal intra-articular fracture compared with extra-articular fracture. Materials and Methods: From February 2006 to June 2008, 21 patients with distal tibia metaphyseal intra-articular fracture and 20 patients with extra-articular fracture were treated operatively by MIPPO technique with LCP and followed for at least one year. In the group with intra-articular fracture, mean age was 48.85 years old and a mean follow-up was 15 months. In the other group with extra-articular fracture, mean age was 52.35 years old and a mean follow-up was 14.5 months. The type of fracture was evaluated using the AO/OTA classification and open-fractures were according to the Gustilo-And gron classification. Radiologic evaluation with fracture healing and tibial alignment, clinical evaluation with Olerud and Molander ankle score and restriction of motion were done for treatment. Results: According to AO/OTA classification, There were 21 type A, 15 type B, 5 type C. Average union time of the intra-articular fracture (type B, C) was 18.7 weeks. Average union time of the extra-articular fracture (type A) was 17.1 weeks. All fractures were healed without malunion. There were no difference of mean restriction angle between intra-articular fracture (ankle dorsiflexion was 3.57 degree, plantar-flexion was 5.95 degree) and extra-articular fracture (ankle dorsiflexion was 3 degree, plantar-flexion was 3.75 degree). There were no difference of Olerud and Molander ankle score between them as a mean score of intra-articular and extra-articular was 89.25, 91.25 each other. As a complication, there were 3 case of skin necrosis, 8 case of discomfortable skin tenting by plate and 1 superficial infection, but could be healed by conservative care. Conclusion: MIPPO technique, combined articular reduction, with LCP of distal tibial metaphyseal fracture was a good method with high functional recovery.

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A Case of Post Kala-Azar Dermal Leishmaniasis in India

  • Tripathy, Kalpalata;Misra, Aparijita;Mallik, Rabinarayn;Misra, Debiprasad;Rout, Niranjan;Rath, Jayshree
    • Parasites, Hosts and Diseases
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    • v.48 no.3
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    • pp.245-246
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    • 2010
  • Post kala-azar dermal leishmaniasis (PKDL) is a rare disease. This is a solitary case report from Orissa, India. We describe a case of PKDL in a 55-year-old male who presented with multiple nodular lesions over face, trunk, and extremities. The patient had been to an endemic area of kala-azar and had a previous history of leishmaniasis. Fine needle aspiration cytology samples from skin nodules revealed Leishmania amastigotes.

Pilomatricoma (Calcifying Epithelioma of Malherbe) - A case report - (모기질 세포종 - 증례 보고 -)

  • Park, Kyeong-Mee;Shim, Jung-Weon;Ko, Ill-Hyang
    • The Korean Journal of Cytopathology
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    • v.2 no.2
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    • pp.168-171
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    • 1991
  • Pilomatricoma is a well defind and characteristic entity histologically, but this tumor may be encountered during aspiration biopsy of subcutaneous mass, and is, occasionally, confused with other neoplasms, particularly squamous cell carcinoma, basal cell carcinoma, and epidermal inclusion cyst. Recently, we have experienced a case of pilomatricoma diagnosed by aspiration biosy. The smear of the aspirate revealed anucleated "ghost" squamous cells, basaloid or basophilic squamous cells and nucleated squamous cells, which lack nuclear features of malignacy. These findings are consistent with pilomatricoma.

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Studies on Lymphocystis Diseases in Sebastes schlegeli (조피볼낙(Sebastes schlegeli)에 유행(流行)한 Lymphocystis병에 대(對)하여)

  • Chun, Seh-Kyu
    • Journal of fish pathology
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    • v.1 no.2
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    • pp.73-76
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    • 1988
  • There prevailed lymphocystis disease with 1 to 2cm in size in the skin and pins of cultured Sebastes schlegeli in fish farms in Tongyoung-gun, Sanyang-myeon, Kon-ri from summer, 1987 to fall, 1988. Though there were some difference between each fish farm, this disease prevailed widely from immature fish to mature fish, less than 10cm to 30cm in body length with about 8 through 80% of infection rate. Sebastes schlegeli with the lymphocystis disease showed combined nipple-shaped mass by doubly, triply propagated lymphocystis. But the author considered that lymphocystis disease was not a direct cause of death of Sebastes schlegeli, the fish showed marked inflammation by seconary infection of pathogenic organisms.

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Lsolation of Diterpene acid from Anisotome Lyallii

  • Lim Jin A;Choi Young;Oh In Kio;Kim Hyung Min;Kim Young Ok;Perry Nigel B;Baek Seung Hwa
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.4
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    • pp.1112-1115
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    • 2003
  • The diterpene acid 1 was isolated from the roots of Anisotome lyallii(Apiaceae/Umbelliferae). The structure of the compound was elucidated as anisotomenoic acid 1 on the basis of spectroscopic methods. This compound was evaluated against P388 murine leukaemia and B 16/F10 melanoma cells.

Immunohistochemistry of Paraffin-embedded Tissues by Super-signal Induction Method (슈퍼시그날 증폭 기술에 의한 파라핀 매몰조직의 면역조직화학염색)

  • Yun Young Gab;Lee Jang Cheon;Jang Seon Il
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.4
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    • pp.1154-1158
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    • 2004
  • The classical ABC (avidin-biotin peroxidase complex) method for immunohistochemistry in the paraffin-embedded tissues bring into being disadvantage such as low sensitivity of antigen detection and highly background. The biotinyl-tyramide conjugation recently introduced for sensitive immunohistochemistry was applied to light microscopy in paraffin-embedded pancreatic and liver tissues. The protocol consists of an indirect method in which 4-5㎛ tissue sections are reacted successively within a specific primary antibody, followed by a biotinylated secondary antibody, streptavidin-horseradich peroxidase (HRP), and then finally with biotinyl-tyramide. The labeling obtained for insulin and collagen antigen tested in pancreatic and liver tissues, respectively, was found to be highly specific with the labeling for each antigen confined to its particular cellular compartment. In this study, fish (flounder) serum was specially applied to remove nonspecific binding. Background levels and nospecific deposition of the staining were negligible. This results suggest that super-signal induction method by biotinyl-tyramide conjugate can readily applied to antigen detection of the paraffin-embedded tissues.

Bacterial diseases of flounder, Paralichthys olivaceus (넙치의 세균성(細菌性) 질병(疾病))

  • Kanai, Kinya
    • Journal of fish pathology
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    • v.6 no.2
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    • pp.197-204
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    • 1993
  • Flounder culture has been developed mainly in the western parts of japan, and, to date, following six bacterial diseases have been reported. Bacterial white enteritis occurs in 16 to 30-day-old flounder larvae and often causes mass mortality in seed production. Bacterium named Vibrio sp. INFL invades and multiplies in the mucosae of posterier part of intestine, and causes desquamative enteritis. Gliding bacterial disease occurs mostly in juvenile stage and in spring to summer. Diseased signs are partial discoloration and erosion of skin and fins. Histologically, epidermis are removed, and the causative bacterium, Flexibacter maritimus, multiplies on the surface of demis and invades into the muscular tissue. Vibriosis caused by Vibrio anguillarum and related organisum is one of the well-known diseases among marine fish. Outbreaks of the disease in flounder culture are relatively few, but mass mortalities in fingerlings due to the disease were reported. An outbreak of nocardiosis in the autumn of 1984 has been reported, but since then the disease scarcely occurred. The disease is characterized by formation of abscesses under the skin and white nodes in the gill, heart, spleen and kidney. Streptococcicosis occurs frequently in recent years. Beta-hemolytic streptococcus is the causative bacterium, which possesses the same biochemical and serological characteristics as $\beta$-streptococci isolated from some marine and freshwater fish, and is seemed to related to Streptococcus iniae. Edwardsiellosis is the disease that causes most damage in flounder culture in Japan. Characteristic symptoms are swelling of abdomen and intestinal protrusion from the anus due to accumulation of ascites. Edwardsiella tarda, a well-known pathogen of freshwater fish, is the causative bacterium of the disease.

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A Case of Metastatic Carcinoma of the Skin (피부전이암 1예)

  • Mun, Byung-Chun;Hwang, Kae-Yong;Choi, Jong-Soo;Choi, Won-Hee;Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.3 no.1
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    • pp.357-360
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    • 1986
  • We report a case of metastatic carcinoma of the skin in 62-year-old male who showed multiple nodules on the anterior chest, scalp, face and left axilla for 2 months' duration. He suffered from lower abdominal discomfortness for 6 months. Histopathologic findings revealed atypical cell nests and some tubular or glandular formation in the dermis and subcutaneous fat tissue. Material in the lumen showed diastase resistant and PAS positive, and alcian blue positive at pH 2.4, but negative pH 0.4. So it represented sialomucin. We did not find primary site of malignant tumor. In view of clinical and histopathological findings, it was considered to be originated from the large intestine.

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Effect of Hovenia dulcis Thunb. Ethanol Extract on the Melanogenesis in B16F10 Melanoma Cell (지구자(枳椇子)에탄올추출물이 B16F10흑색종세포의 멜라닌생성에 대한 효과)

  • Kim, Jun-Ho;Moon, Dea-Won;Choi, Mi-Eun;Lim, Gyu-Sang;Mun, Yeun-Ja;Woo, Won-Hong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.2
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    • pp.337-342
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    • 2009
  • Acquired pigmentary skin diseases such as abnormal melanogenesis, vitiligo, chloasma and inflammatory pigmentation are related to regulate the melanin production, In this study, an ethanol extract of Hovenia dulcis Thunb.(EHD) makedly inhibited melanin biosynthesis and suppressed, the protein expression of tyrosinase, tyrosinase-related protein 1(TRP-1), and tyrosinase-related protein 2(TRP-2) in B16F10 cells. On the other hand, EHD did not inhibit mushroom tyrosinase activity. These results indicate that EHD may contribute to the inhibition of melanin biosynthesis through regulating tyrosinase activity and expression, and serve as a new candidate in the design of new skin-whitening or therapeutic agents.