Lsolation of Diterpene acid from Anisotome Lyallii

  • Lim Jin A (Department of Chemistry, Otago University) ;
  • Choi Young (Department of Skin and Care, Kimcheon Science College) ;
  • Oh In Kio (Department of Environmental Science, Wonkwang Health Science College) ;
  • Kim Hyung Min (Department of Pharmcology, School of Oriental Medicine, Kyunghee University) ;
  • Kim Young Ok (Department of Clinical Pathology, Jeonju Kijeon Womens College) ;
  • Perry Nigel B (Plant Extracts Resarvh Unit, New Zealand Institute for Crop & Food Research Limited) ;
  • Baek Seung Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)
  • Published : 2003.08.01

Abstract

The diterpene acid 1 was isolated from the roots of Anisotome lyallii(Apiaceae/Umbelliferae). The structure of the compound was elucidated as anisotomenoic acid 1 on the basis of spectroscopic methods. This compound was evaluated against P388 murine leukaemia and B 16/F10 melanoma cells.

Keywords

References

  1. Phytomed. v.2 no.4 Cytotoxicity and antimicrobial activity of plants from New Zealand's subantarctic islands. Lorimer,S.D.;Barns,G.;Evans,A.C.;Foster,L.M.May,B.C.H.;Perry,N.B.;Tangney,R.S.
  2. J.Essent.Oil Res. Exxential Oils of Anisotome antipoda and Anisotome latifolia from New Zealand's subantarctic Islands. Van Klink,J.W.;Perry,N.B.
  3. J.Essent.Oil Res. v.7 Composition of the essential oils of ligusticum mutellina(L.) Crantz (Apiaceae). Brandt,J.J;Schultze,W.
  4. PERU report 1998 Unpublished results. Bandeen,P.;Perry,N.B.;Weavers,R.T.
  5. PERU report Diterpenes from Anisotome flexuosa. Van Klink,J.W.;Perry,N.B.
  6. Tetrahedron Lett. v.40 A new irregular diterpene skeleton from Anisotome flexuosa. Van Klink,J.W.;Barlow,A.J.;Perry,N.B.;Weavers,R.T. https://doi.org/10.1016/S0040-4039(98)02621-5
  7. Cancer Res v.47 Evaluation of a tetrazolium-based semiautomated colorimetric assay:assessment of chemosensitivity testing. Carmichael,J.;Degraff,W.G.;Gazear,A.F.;Minna,J.D.;Mitchell,J.B.
  8. Immunol.Methods v.65 Rapid colorimetric assays for cellular growth and survival:application to proliferation and cytotoxicity assays. Mosmann,T. https://doi.org/10.1016/0022-1759(83)90303-4
  9. Contributions pluridisciplinaires a la Systematique(Paru 1978) Generic problems in Australasian Apioideae (Umbelliferae). Actes du 2eme Symposium International sur les Ombelliferes (Perpignan,1977). Dawson,J.W.;Webb,C.J.
  10. New Zealand Alpine Plants Mark,A.F.;Adams,N.M.
  11. PERU Report Analyses of native Apiaceae extracts:Anisotome and Gingidia. Van Klink,J.W.;Perry,N.B.