• Journal of the Korean Data and Information Science Society
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• 제22권1호
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• pp.57-64
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• 2011

이 연구에서는 최근 체육영재선정에 공통적으로 사용되고 있는 스포츠영재성 검사 항목과 코스타스 점수간의 연관성 분석을 통해 상대적으로 중요한 검사 항목과 그렇지 않은 검사 항목을 통계적으로 밝혀내는 데 목적이 있다. 이 연구를 위해 2010년도 서울지역 (강동구, 송파구, 노원구, 광진구 등)과 경기지역 (의정부시, 가평군, 구리시 등) H대학 체육영재양성사업에 지원한 201명의 초등학교 학생들의 자료가 사용되었으며, 육상 네 종목 (투척, 도약, 단거리, 중장거리), 수영 및 체조 종목의 코스타스 점수와 1차 스포츠영재성 검사에서 얻은 기본 체격, 체력 운동능력, 생리적 기능 정보를 이용하였다. 구체적으로 순수한 연관성 분석을 위해 피어슨상관계수와 편상관계수를 사용하였으며, 중요한 검사 항목 선택을 위해 단계적 회귀분석을 이용하였다. 그 결과 골연령, 체중, 흉위와 50m달리기, 하프스쿼트점프가 6개 코스타스 점수에 미치는 영향이 상대적으로 미약한 것으로 나타났다.

• Molecules and Cells
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• 제28권6호
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• pp.565-573
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• 2009

The pig could be a useful model to characterize molecular aspects determining several delicate phenotypes because they have been bred for those characteristics. The Korean native pig (KNP) is a regional breed in Korea that was characterized by relatively high intramuscular fat content and reddish meat color compared to other western breeds such as Yorkshire (YS). YS grew faster and contained more lean muscle than KNP. We compared the KNP to Yorksire to find molecular clues determining muscle characteristics. The comparison of skeletal gene expression profiles between these two breeds showed molecular differences in muscle. We found 82 differentially expressed genes (DEGs) defined by fold change (more than 1.5 fold difference) and statistical significance (within 5% of false discovery rate). Functional analyses of these DEGs indicated up-regulation of most genes involved in cell cycle arrest, down-regulation of most genes involved in cellular differentiation and its inhibition, down-regulation of most genes encoding component of muscular-structural system, and up-regulation of most genes involved in diverse metabolism in KNP. Especially, DEGs in above-mentioned categories included a large number of genes encoding proteins directly or indirectly involved in p53 pathway. Our results indicated a possible role of p53 to determine muscle characteristics between these two breeds.

• 대한수의학회지
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• 제33권3호
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• pp.465-469
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• 1993

낭미충(Cysticercus cellutosae)에 자연감염된 돼지의 각 장기를 조직학적으로 검사하였던 바 다음과 같은 결과를 얻었다. 피막을 형성하는 낭미충은 골격근, 파하직, 심장 및 뇌조직에서 관찰되었다. 조직학적 소견으로는 골격근의 근막내와 심장 심외막하에서 낭충주위는 피막의 형성과 함께 급성 염증반응이 인정되었고 부위에 따라서는 교원섬유 및 선유아세포의 증식에 의한 두터운 피막이 관찰되었고 인접한 골격근 또는 심근과 견고하게 부착된 예도 있었다. 피막주위에서는 호산구, 임파구, 대식세포의 침윤이 부위에 따라 경미하거나 또는 심한 형태로 다양하였다. 대뇌의 연막하에 형성된 피막주위에는 혈관과 결합조직의 증식이 현저하였고, 혈관주위 원형세포의 침윤과 임파결절 모양의 구조가 인정되었다. GFAP 면역반응은 혈관주위를 따라 GFAP 양성의 섬유가 잘 발달되었고 피막낭 외측을 따라 전체를 둘러싸는 경항이었다. 결론적으로 유구낭미충 감염돼지의 조직소견은 감염 장기에 따라 염증반응이 다양하고 낭충의 피막은 감염 초기에 형성된 것으로 추정되었다.

• 대한치과교정학회지
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• 제53권4호
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• pp.241-253
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• 2023

Objective: To evaluate the following null hypothesis: the skeletal and dentoalveolar expansion patterns in the coronal and axial planes are not different with two different types of microimplant-assisted rapid palatal expansion (MARPE) systems. Methods: Pretreatment (T0) and post-MARPE (T1) cone-beam computed tomography (CBCT) images of 32 patients (14 males and 18 females; mean age, 19.37) were analyzed. We compared two different MARPE systems. One MARPE system included the maxillary first premolars, maxillary first molars, and four microimplants as anchors (U46 type, n = 16), while the other included only the maxillary first molars and microimplants as anchors (U6 type, n = 16). Results: In the molar region of the U6 and U46 groups, the transverse expansion at the midnasal, basal, alveolar, and dental levels was 2.64, 3.52, 4.46, and 6.32 mm and 2.17, 2.56, 2.73, and 5.71 mm, respectively. A significant difference was observed in the posterior alveolar-level expansion (p = 0.036) and posterior basal-bone-level expansion (p = 0.043) between the groups, with greater posterior skeletal and alveolar expansion in the U6 group. Conclusions: Compared with the U46 group, the U6 group showed greater posterior expansion at the alveolar and basal-bone levels, with an almost parallel split. Both groups showed a pyramidal expansion pattern in the coronal view.

• 대한한의학회지
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• 제45권1호
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• pp.65-79
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• 2024

Objectives: The purpose of this study is to evaluate weight change and analyze adverse events in post-menopausal obese women with Gamitaeeumjowee-tang for weight loss. Methods: A retrospective chart review was conducted for medical records of 115 post-menopausal obese women (body mass index, BMI≥25 kg/m²) who were administered with Gamitaeeumjowee-tang for 12 weeks for the purpose of weight loss. Weight, skeletal muscle ratio and BMI changes were compared before and after the program. Adverse events were evaluated by causality, severity and system-organ classes. Results: A total of 115 patients were included in this study. The average total weight loss in post-menopausal women was 5.72±2.04kg(p<0.001) and the average weight loss rate was 8.06±2.70%(p<0.001). After the 12-week program, the body fat rate was significantly decreased(3.76±2.20%)(p<0.001) and the skeletal muscle ratio was significantly increased(2.07±1.24%)(p<0.001). There were no significant differences in weight loss, skeletal muscle ratio change and body fat rate change depending on the number of hospital visits. Insomnia was frequently reported throughout the period, and no serious adverse events were reported. Conclusions: This study showed the potential that weight management treatment with Gamitaeeumjowee-tang could be a good way to lose weight of post-menopausal obese women without serious adverse events. Continuous well designed clinical studies are needed.

• 산업경영시스템학회지
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• 제24권66호
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• pp.1-10
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• 2001

Simulation-Based Expert System(SIMBES) is a very effective tool to solve complex antral hard problems. The SIMBES model includes a simulator, a feature extractor, a machine learning system, a performance evaluator, and a Knowledge-Based Expert System(KBES). Since SIMBES depends on Problem domains, a schedule-based material requirements planning problem, which is NP-hard, was selected to exemplify the SIMBES model. To implement the SIMBES application in Smalltalk paradigm, a system class hierarchy was constructed. The hierarchy consists of five large classes such as Job Generator, Job Scheduler, Job Evaluator, Inference Engine, and Executive System. Several classes inside these classes were identified. Additionally, instance protocols about all classes have been described in terms of messages and pseudo methods. These protocols can be implemented easily by any other object-oriented languages. Furthermore, these results may be used as a skeletal system to develop a new SIMBES efficiently, especially when the application is related to other scheduling problems.

• 대한소아치과학회지
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• 제36권3호
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• pp.464-474
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• 2009

상악 대구치의 원심이동이 요구되는 경우, 구외견인, Wilson distalizing arches, 가철식 스프링 장치 그리고 Schwarz plate-type 장치 등을 사용 할 수 있다. 그러나 이러한 전통적인 대구치의 원심이동 장치들로 치료에 성공하기 위해서는 환자의 협조가 필수적이기 때문에 많은 소아치과 의사들은 환자 의존성을 최소화하고 임상가가 통제 할 수 있는 장치들로 전환하고 있다. 이 중 가장 일반적인 것이 pendulum 장치인데, 고정원이 되는 전방치아의 원하지 않는 이동과 고정원 소실, 그리고 구개부 고정원이 좋지 않은 경우 원하는 정도의 구치부 원심이동을 얻기 어렵다는 단점이 있다. 이와 같은 전통적인 pendulum의 단점을 해결하고자, SAS(Skeletal Anchorage System)를 pendulum에 접목하여 골에서 직접 지지를 얻는 변형된 형태의 pendulum, 즉 bone-supported pendulum을 제작하여 장착 시킨 후 주기적인 관찰을 시행하였다. 본 증례는 혼합치열기 환자를 대상으로 bone-supported pendulum을 사용하여 안정된 고정원 유지, 원치 않는 치아이동의 최소화 및 양호한 상악 대구치 원심이동 등을 관찰하였기에 이를 보고하는 바이다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제31권6호
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• pp.485-491
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• 2009

Postoperative skeletal stability was evaluated in combination of Le Fort I and U-shaped osteotomies for superior repositioning of maxilla in bi-maxillary surgeries in 30 consecutive patients. The fifteen patients underwent Le Fort I osteotomy alone and the other fifteen patients underwent Le Fort I and U-shaped osteotomies. In all patients, the maxilla was first osteomized and fixed with absorbable plates system. A bilateral sagittal split ramus osteotomy (BSSRO) of the mandible was then carried out and fixation was performed using absorbable plates. Maxillo-mandibular fixation with rubber ring was used for two weeks post-operatively in all patients. Lateral cephalograms were obtained pre-operatively, 1 day post-operatively, 6 months after surgery. The changes in anterior nasal spine (ANS), point A, upper incisior (U1), and point of maxillary tuberosity (PMT) were examined. The maxillas in the fifteen patients of both examination group were repositioned nearly in their planned positions during surgery and no significant post-operative changes in the examined points of the maxilla were found. These results suggest that a combination of a Le Fort I and U-shaped osteotomy is a useful technique for reliable superior repositioning of the maxilla. The post-operative change in the maxilla using this combination osteotomy was comparatively stable.

• Structural Engineering and Mechanics
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• 제57권6호
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• pp.1065-1084
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• 2016

The analysis and design of skeletal structures is greatly influenced by the behaviour of beam-to-column connections, where patented designs have led to a wide range of types with differing structural quantities. The behaviour of beam-to-column connections plays an important role in the analysis and design of framed structures. This paper presents an overview of the influence of connection behaviour on structural stability, in the in-plane (bending) mode of sway. A computer-based method is presented for geometrically nonlinear plane frames with semi-rigid connections accounting for shear deformations. The analytical procedure employs transcendental modified stability functions to model the effect of axial force on the stiffness of members. The member stiffness matrix were found. The critical load has been searched as a suitable load parameter for the loss of stability of the system. Several examples are presented to demonstrate the validity of the analysis procedure. The method is readily implemented on a computer using matrix structural analysis techniques and is applicable for the efficient nonlinear analysis of frameworks. Combined with a parametric column effective length study, connection and frame stiffness are used to propose a method for the analysis of semi-rigid frames where column effective lengths are greatly reduced and second order (deflection induced) bending moments in the column may be distributed via the connectors to the beams, leading to significant economies.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.1373-1377
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• 2003

Current prostheses for amputees are generally extrinsic wearing socket type that the coupling between body stump and appliance wraps the soft tissue and this structure causes several problems :applying direct weight to soft tissue such as skin and muscle, skin trouble of contacting area and pain. In this study, osseointegration implant is a method to directly connect prosthesis to the residual stump skeletal tissue of arm, finger and leg through surgical operation. Technology presented in this paper essentially solves the problems of pain and abnormal weight transfer system indicated above and recovers the functions of the amputated arm and leg. In this paper, implant shape was designed for the first step for the development of osseointegration implant and then we studied the possibility to apply this osseointegration implant to human body by performing implant insertion operation to beagle tibia for the clinical animal test and normal beagle's gait analysis was executed in order to quantitatively verify the beagle's skeletal functions after the implant insertion.