• Journal of Pharmaceutical Investigation
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• v.20 no.4
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• pp.199-203
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• 1990

The pharmacokinetics of propranolol administered orally (10 me/kg) was investgated in the rabbits of carbon tetrachloride induced hepatic failure. The plasma concentration and relative bioavailability of propranolol were increased significantly in hepatic failure rabbits, compared with those of normal rabbits. There were significant relationship between GOT, GPT value and bioavailability parameters of propranolol. In short, dosage regimen of propranolol is considered to be adjusted in dose size and dosing interval using GOT or GPT an index.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.7
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• pp.1044-1052
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• 2015

The aim of this modelling study was to investigate the effect of large herd size (and land areas) on walking distances and milking interval (MI), and their impact on milk yield and economic penalties when 50% of the total diets were provided from home grown feed either as pasture or grazeable complementary forage rotation (CFR) in an automatic milking system (AMS). Twelve scenarios consisting of 3 AMS herds (400, 600, 800 cows), 2 levels of pasture utilisation (current AMS utilisation of 15.0 t dry matter [DM]/ha, termed as 'moderate'; optimum pasture utilisation of 19.7 t DM/ha, termed as 'high') and 2 rates of incorporation of grazeable complementary forage system (CFS: 0, 30%; CFS = 65% farm is CFR and 35% of farm is pasture) were investigated. Walking distances, energy loss due to walking, MI, reduction in milk yield and income loss were calculated for each treatment based on information available in the literature. With moderate pasture utilisation and 0% CFR, increasing the herd size from 400 to 800 cows resulted in an increase in total walking distances between the parlour and the paddock from 3.5 to 6.3 km. Consequently, MI increased from 15.2 to 16.4 h with increased herd size from 400 to 800 cows. High pasture utilisation (allowing for an increased stocking density) reduced the total walking distances up to 1 km, thus reduced the MI by up to 0.5 h compared to the moderate pasture, 800 cow herd combination. The high pasture utilisation combined with 30% of the farm in CFR in the farm reduced the total walking distances by up to 1.7 km and MI by up to 0.8 h compared to the moderate pasture and 800 cow herd combination. For moderate pasture utilisation, increasing the herd size from 400 to 800 cows resulted in more dramatic milk yield penalty as yield increasing from c.f. 2.6 and 5.1 kg/cow/d respectively, which incurred a loss of up to $AU 1.9/cow/d. Milk yield losses of 0.61 kg and 0.25 kg for every km increase in total walking distance (voluntary return trip from parlour to paddock) and every one hour increase in MI, respectively. The high pasture utilisation combined with 30% of the farm in CFR in the farm increased milk yield by up to 1.5 kg/cow/d, thereby reducing loss by up to $0.5/cow/d (c.f. the moderate pasture and 800 cow herd scenario). Thus, it was concluded that the successful integration of grazeable CFS with pasture has the potential to improve financial performance compared to the pasture only, large herd, AMS.

• Fashion & Textile Research Journal
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• v.16 no.1
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• pp.118-127
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• 2014

This study proposed a revision of standard sizing system for infant clothing to provide exact information for consumers and manufacturers. The size designation was set up by compensating the defect of existing system. Basic body measurement and reference body measurement were analysed according to size designation. The ages of the infants ranged from 0 to 36 month in accordance with safety standard of KC Self-Regularity Safety Confirmation. The results are as follows: Size designation for infant clothing was based on height that was basic body measurement. Chest girth, waist girth, head girth, arm length, foot length and weight were also analysed according to age of the month. It was proposed that height could be written alone and height with age of month did together for size designation. Size intervals of basic and reference body measurements were fixed as follows: size intervals are 5 cm in height, 2 cm in chest girth, 2 cm in waist girth, 1 cm in head girth, 2 cm in arm length, 0.5 cm in foot length and 2 kg in weight. The distributions of height and chest girth showed normal distributions. As height was taller, chest girth was also bigger. But the distribution of waist girth didn't show remarkable change with age of month. The distributions of arm length and weight showed remarkable difference with growth in 0~9 months, but the amount of growth variation got less in 12~18 months.

• Korean Journal of Radiology
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• v.21 no.11
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• pp.1248-1255
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• 2020

Objective: To analyze long-term follow-up sonographic findings of intrathyroidal thymus in children. Materials and Methods: Among 1259 patients with congenital hypothyroidism under 15 years of age who underwent thyroid ultrasonography (US), 41 patients were diagnosed with an intrathyroidal thymus based on US criteria, i.e., hypoechoic solid lesion with punctate and linear echogenicity. In 26 patients aged one to 14 years old, the last follow-up US was performed after 6 to 132 months and compared with the initial US. The lesion was considered to decrease in size if there was a change of more than 2 mm in any dimension. The margin change was divided into well-defined and indistinct, blurred. When the echogenicity changed to a hyperechoic from a characteristic thymic echogenicity pattern, the pattern was considered a hyperechogenic. The changes in size were compared with the changes in shape, margin, and echogenicity pattern. The changes in size, shape, margin, and echogenicity were analyzed the association with the age of last follow-up. Statistical analysis was conducted using the chi-squared test and logistic regression. Results: Fifteen (57.7%) cases were stable in size, and 11 (42.3%) decreased in size, including one that disappeared. Ten (38.5%) cases changed to indistinct margins from initially well-defined margins including one case of initially indistinct margin. Six (23.1%) changed to hyperechogenic, from initially characteristic thymic echogenicity patterns. When follow-up change was compared, decreases in size were significantly associated with lesion changes to indistinct margins (p = 0.004). The age at last follow-up was significantly associated with change to hyperechogenicity (odd ratio, 2.141; 95% confidence interval, 1.144-4.010, p = 0.017). Conclusion: On follow-up US, an intrathyroidal thymus may be decreased in size, with indistinct margins, or show changes to a hyperechoic mass. Decreases in size may be associated with changing to indistinct margins, and changes to hyperechogenicity may be associated with increasing age.

• Communications for Statistical Applications and Methods
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• v.14 no.1
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• pp.81-92
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• 2007

This paper consider trinomial group testing concerned with classification of N given units into one of k disjoint categories. In this paper, we propose Bayesian inference for estimating individual category proportions using the trinomial group testing model proposed by Bar-Lev et al. (2005). We compared a relative efficience (RE) based on the mean squared error (MSE) of MLE and Bayes estimators with various prior information. The impact of different prior specifications on the estimates is also investigated using selected prior distribution. The impact of different priors on the Bayes estimates is modest when the sample size and group size we large.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.16 no.2
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• pp.70-77
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• 2007

The application of focused ion beam(FIB) technology has been broadened in the fabrication of nanoscale regime. The extended application of FIB is dependent on complicated reciprocal relation of operating parameters. It is necessary for successful and efficient modifications on the surface of silicon substrate. The primary effect by Gaussian beam intensity is significantly shown from various aperture size, accelerating voltage, and beam current. Also, the secondary effect of other process factors - dwell time, pixel interval, scan mode, and pattern size has affected to etching results. For the process analysis, influence of the secondary factors on FIB micromilling process is examined with respect to sputtering depth during the milling process in silicon material. The results are analyzed by the ratio of signal to noise obtained using design of experiment in each parameter.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2015.07a
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• pp.179-180
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• 2015

The variety of organic and inorganic pollutants are introduced to coastal sediment and making highly contaminated due to rapid development of industralization and economic development. Numerous contaminants are release into marine sediment and it significantly affect marine aquatic environment. In the present study stated the optimize the biostimulant ball (BSB) in coastal sedimentand stabilse the heavy metals present in the sediment. The effective variables like BSB size, distance and month variables on Cu stabilization was determined by using Response surface methodology(RSM). The analysis of variance (ANOVA) and coefficient determination (R2) of Cu reduction 0.9610 and maximum stabilisation was obtained in 3cm ball size and 5.5cm distance and 4 month interval time. This result revealed that the BSB in effective for Cu reduction in coastal sediment.

• Journal of the Korea Society for Simulation
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• v.5 no.2
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• pp.59-72
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• 1996

The purpose of this study is to make an improvement to the batch-means method, which is a procedure to construct a confidence interval(c.i.) for the steady-state process mean of a stationary simulation output process. In the batch-means method, the data in the output process are grouped into batches. The sequence of means of the data included in individual batches is called a batch-menas process and can be treated as an independently and identically distributed set of variables if each batch includes sufficiently large number of observations. The traditional batch-means method, therefore, uses a batch size as large as possible in order to. destroy the autocovariance remaining in the batch-means process. The c.i. prodedure developed and empirically tested in this study uses a small batch size which can be well fitted by a simple ARMA model, and then utilizes the dependence structure in the fitted model to correct for bias in the variance estimator of the sample mean.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2001.05a
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• pp.189-193
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• 2001

The performance of printer can be determined by the printing speed, noise level, printing quality which includes the resolution, regularity of printed matter and etc. Among them, printing quality mostly depends on the irregularity of the line spacing and dot size. The irregular line spacing and dot size in laser beam printer are mainly from the jitter which comes from the vibration of Organic Photo Conductive(OPC) drum and the Laser Scanning Unit(LSU). Jitter due to the vibration of LSU appears as high-frequency component which occurs 100-300$\mu\textrm{m}$ interval in printed matter and the causes of it can be estimated as the vibration of polygon motor, case, reflecting mirror and etc. In this paper, vibration characteristics of the LSU under development are investigated and the strategy for improvement of the dynamic characteristics is established and its validity is demonstrated.

• Journal of Mechanical Science and Technology
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• v.16 no.4
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• pp.501-511
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• 2002

This paper presents a study of the effect of rolling temperature, roll gap (pass height), initial specimen size and steel grades of specimens on the roll force in round-oval-round pass sequence by applying approximate method and verifications through single stand pilot rod rolling tests. The results show that the predicted roll forces are in good agreement with the experimentally measured ones. The approximate model is independent of the change of roll gap, specimen size and temperature. Thus, the generality of the prediction methodology employed in the approximate model is proven. This study also demonstrates that Shida's constitutive equation employed in the approximate model needs to be corrected somehow to be applicable for the medium and high carbon steels in a lower temperature interval (700∼900$\^{C}$).