• 제목/요약/키워드: Single-body

검색결과 2,101건 처리시간 0.03초

신바로 약침의 SD 랫드와 비글견에 대한 단회 근육투여 독성시험 (Study on Single-dose Intramuscular Toxicity of Shinbaro Pharmacopuncture in Sprague-Dawley (SD) Rats and Beagle Dogs)

  • 이진호;정화진;이인희;이재웅;김은지;김민정
    • 한방재활의학과학회지
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    • 제25권3호
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    • pp.1-9
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    • 2015
  • Objectives To evaluate Shinbaro Pharmacopuncture safety through analysis of potential single-dose intramuscular toxicity of Sinbaro Pharmacopucture in SD rats and Beagle dogs. Methods Single-dose intramuscular toxicity of Shinbaro Pharmacopuncture was assessed in accordance with Korea Food and Drug Administration Guidelines for toxicity testing of Medicinal Products. The SD rats were treated intramuscularly with Shinbaro Pharmacopuncture at doses of 0, 4.6, 9.2, and 18.5 mg/kg, respectively. The Beagle dogs were treated intramuscularly with Shinbaro Pharmacopuncture at doses of 2.3, and 4.6 mg/kg, respectively, and after 3 days, the procedure was repeated a second time at doses of 0.6, and 1.2 mg/kg, respectively, for toxicity testing. Mortality, change in body weight, and necropsy findings were examined for the study period. Results There were no mortalities, general symptoms, or body weight changes in the SD rats. While pyelectasis of the left kidney was observed in a male rat in the 4.6 mg/kg administration group, natural occurrence is common, and does not appear to be related with the test substance. No mortalities were observed in the Beagle dogs. In assessment of general symptoms, a female dog in the 9.2 mg/kg group displayed body weight decrease due to leftover food, but the change in body weight was within the normal range seen at 6~7 months, and the necropsy findings were not significant. The toxicity of the test substance appears to be minimal. Conclusions The results suggest that the lethal dose 50 ($LD_{50}$) and approximate lethaldose (ALD) value in single intramuscular administration of Shinbaro Pharmacopuncture in SD rats and Beagle dogs are higher than 18.5 mg/kg.

광전 방식에 의한 피하 지방층의 비만도 측정에 관한 연구 (A Study on The Fat Measurement at Subcutaneous Adipose by Optical and Electrical Method)

  • 오세용;이영우
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2008년도 춘계종합학술대회 A
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    • pp.405-407
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    • 2008
  • 광학적 방식에 의한 비침습적으로 신체 전체의 비만도를 측정하기 위해서는 단일 특정 부위에서 측정하는 것은 오차가 너무 크기 때문에 여러 부위에서 측정하고 이를 통계적 방법에 의해서 정확도를 높일 수 있다. 이를 위해서 백색광 LED광원을 이용하고 전기적 방식인 BIA(Bio-electrical Impedance)방식으로 동시에 측정하여 광전기적 지방측정에 관한 상관식을 유도하였다.

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e-Book 타이포그래픽에 관한 연구 (A Study on e-Book typographic)

  • 이영호;차재영;구철회
    • 한국인쇄학회지
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    • 제22권1호
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    • pp.65-74
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    • 2004
  • This study analyzed the main bodies, sizes of litters, spaces between letters, Words, lines, length of lines, sizes of main body and margin, Position of the main bodies of PDF(Portable Document Format) in high schools and "the criteria of reading system for the textbooks" which was suggested by the Department of Education and Provided some suggestions for the improvement. First, it is judged that spaces of the main body of textbooks should be shrunken to make the ratio of 50:50 between the main body and space margin. Second, it is judged that the main body should be placed in the center of text page. Third, the results of the above findings showed that it would be difficult to deal with the task of deciding space and position or the main body and marginal space in a form of single project, because there are many variables involved and psychologically complicated elements which can not be measured objectively.

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A distributed relay selection algorithm for two-hop wireless body area networks

  • Kim, Seung-Ku;Joo, Yang-Ick
    • Journal of Advanced Marine Engineering and Technology
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    • 제41권2호
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    • pp.156-162
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    • 2017
  • This paper investigates two-hop extension communication in wireless body area networks. Many previous studies have demonstrated that two-hop extended topology outperforms single-hop topology. Although many researchers have proposed using two-hop extension communication to improve link reliability, no one has considered using a relay selection algorithm or provided a suitable solution for wireless body area networks. The design goal of the proposed algorithm is selecting a proper relay node to retransmit failed packets distributively. The proposed algorithm configures the carrier sensing period to choose one relay node promptly without requiring additional interaction. We analyze the link conditions corresponding to various body postures and investigate which factors are proper to determine the carrier sensing period. The empirical results show that the proposed algorithm reduces the expected number of transmissions required to deliver a packet successfully.

Integrate-and-Fire Neuron Circuit and Synaptic Device with Floating Body MOSFETs

  • Kwon, Min-Woo;Kim, Hyungjin;Park, Jungjin;Park, Byung-Gook
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제14권6호
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    • pp.755-759
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    • 2014
  • We propose an integrate-and-fire neuron circuit and synaptic devices with the floating body MOSFETs. The synaptic devices consist of a floating body MOSFET to imitate biological synaptic characteristics. The synaptic learning is performed by hole accumulation. The synaptic device has short-term and long-term memory in a single silicon device. I&F neuron circuit emulate the biological neuron characteristics such as integration, threshold triggering, output generation, and refractory period, using floating body MOSFET. The neuron circuit sends feedback signal to the synaptic transistor for long-term memory.

편평발에서 Low-dye 테이핑이 한발 서기 동안 근활성도 변화에 미치는 영향 (The Effect of Low-dye Taping on Muscle Activity during Single-leg Standing in People with Flatfoot)

  • 박민철
    • 대한물리의학회지
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    • 제8권4호
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    • pp.533-538
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    • 2013
  • PURPOSE: This study was performed to investigate the effect of Low-dye Taping on muscle activity during single-leg standing in subjects with flexible flatfoot. METHODS: Thirteen able-body volunteers who had flexible flatfoot were recruited for this study. Subjects were measured navicular drop test to evaluate pronation of foot and muscle activity during single-leg standing before and after taping. The muscle activity was recorded using surface EMG from the tibialis anterior and the peroneus longus during single-leg standing on stable and unstable surface. RESULTS: The results show that the navicular drop height and the tibialis anterior muscle activity were significantly decreased after Low-dye taping. CONCLUSION: The results suggest that Low-dye taping could be useful in managing overuse of the tibialis anterior by reducing their level of activation during single-leg standing.

갈근탕 추출물의 단회투여 독성 시험 (Single Dose Toxicity Study on Galgeuntang in Mice)

  • 이지혜;이재훈;마충제;마진열
    • 한국한의학연구원논문집
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    • 제15권1호
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    • pp.79-83
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    • 2009
  • In this study, we investigated the single dose toxicity and safety about water-extracted Galgeuntang. To evaluate single dose toxicity, 20 male and 20 female ICR mice were observed survival rates, general toxicity, changes of body weight for 14 days after single oral administration of 0 (control group), 1250, 2500 and 5000mg/kg Galgeuntang. And after 14 day, We observed autopsy. Compared with the control group, we could not find any toxic alteration in all treated groups (1250, 2500 and 5000 mg/kg). LD50 of Galgeuntang might be over 5000mg/kg and it is very safe to ICR mice.

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1축 대차용 철도차량의 동특성 해석 (Dynamic Analysis of Railway Vehicle Having Single Axle Bogie)

  • 양희주;오택열
    • 한국정밀공학회지
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    • 제18권3호
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    • pp.84-89
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    • 2001
  • Studied in this paper was the vehicle dynamics simulation for development of single axle bogie using the multi-body dynamics simulation program(VAMPIRE). Single axle bogie vehicle is to the crew of freight vehicle. Method of analysis for dynamic behaviors of vehicle having single axle bogie was carried by UIC(International Union of Railways) code 518 and results of analysis were presented in terms of the hunting stability and the derailment ratio and the sum of wheel/rail lateral force. The results of analysis meet the criteria proposed by UIC.

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DYNAMICAL EVOLUTION OF ROTATING SINGLE-MASS STELLAR CLUSTER

  • ARDI ELIANI;SPURZEM RAINER;MINESHIGE SHIN
    • 천문학회지
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    • 제38권2호
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    • pp.207-210
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    • 2005
  • We study the influence of rotation on the dynamical evolution of collisional single-mass stellar clusters up to core-collapse by using N-body simulations. Rotating King models which are characterized by dimensionless central potential parameter $W_o$ and the rotation parameter $W_o$ are used as initial models. Our results show that inner shells slowly contract until core-collapse phase is reached, followed by a slow expansion. Angular momentum is transported outward, while the core is rotating even faster than before, as predicted by gravogyro catastrophe theory. We confirm that rotation plays an important role in accelerating the dynamical evolution of stellar cluster, in particular in accelerating the core collapse.

차체접합과 관련한 접합 강도 평가 (Strength Evaluation of Adhesive Bonded Joint for Car Body)

  • 이강용;김종성;공병석;우형표
    • 한국자동차공학회논문집
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    • 제6권1호
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    • pp.143-150
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    • 1998
  • The evaluation of joint fatigue strength of light weight materials for electrical vehicle body has been performed through single lap joint tests with the design parameters such as joint style, adherend, bonding overlap length and bonding thickness. Fatigue strength was evaluated through 5-Hz, tension-tension, load controlled test with the stress ratio zero value. It is experimentally observed that fatigue strength of joint increases for the increase of overlap length. The combinations of Al-Al and Al-FRP adherends show that fatigue strength of joint is hardly changed for the increase of bonding thickness, but FRP-FRP adherend specimen shows that fatigue strength of joint increases after decreases for the increase of bonding thickness. Al-Al adherend specimen has much higher fatigue length than Al-FRP and FRP-FRP adherend specimens. Riveting at adgesive bonded joint gives little effect on fatigue strength.