• 제목/요약/키워드: Single-blind test

검색결과 62건 처리시간 0.024초

월경곤란증의 자하거 약침효과에 관한 연구 (Effect of Hominis placenta Pharmacopuncture on the Dysmenorrhea (A Pilot study, Single blind, Randomized, Controlled Clinical Trial))

  • 김수민;장선희;김철홍;윤현민;송춘호;안창범;장경전
    • 대한약침학회지
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    • 제11권3호
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    • pp.123-131
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    • 2008
  • Objective: This study was designed to evaluate the effect of Hominis placenta Pharmacopuncture treatment on Dysmenorrhea of Women. Methods: 49 subjects who were suffering from dysmenorrhea volunteered to answer the MMP(Measure of Menstrual Pain) and MSSL(Menstrual Symptom Severity List) questionnaire. They were divided into two groups, a Hominis placenta Pharmacopuncture treatment group(Experiment al group, n=25) and a Normal Saline(N/S) treatment group(Control group, n=24). The two groups were injected on the $CV_4,\;S_{36},\;Sp_9$ and $Sp_6$ acupuncture point. They were treated totally five times depending on the individual menstruation cycles. The scores of MMP and MSSL were measured overall three times before and after the menstruation cycle. The collected data were analyzed as paired t-test, independent t-test using SPSS 12.0 WIN Program. Results: As a result of the evaluation by MMP and MSSL, a significant improvement on dysmenorrhea was made in the two groups(p<0.05), and both scores of Experiment group were decreased more than Control group. But there was no significant difference between the two groups. Conclusions: The Hominis placenta Pharmacopuncture treatment and the Normal Saline treatment were effective in decreasing the symptom of Dysmenorrhea.

Effects of body weight-supported treadmill training combined with ball-kicking on balance and gait of subacute stroke patients

  • Cho, Juchul;Lee, Eunsang;Lee, Seungwon
    • Physical Therapy Rehabilitation Science
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    • 제4권2호
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    • pp.73-78
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    • 2015
  • Objective: This study focused on subacute stroke patients who were asked to kick a ball while walking on a treadmill. The aim of the study was to determine the effect of a body weight-supported treadmill training (BWSTT) combined with ball-kicking on muscle strength, balance, and gait. Design: Single blind, randomized controlled trial. Methods: Twenty stroke patients who volunteered to participate in this study were randomly assigned to either the BWSTT combined with ball-kicking (BWSTT-BK; 10 participants) group or the BWSTT group (10 participants). Participants in the BWSTTBK group performed treadmill walking combined with simultaneous ball-kicking for 30 minutes daily for 5 weeks. Participants from the BWSTT group performed only treadmill walking. The muscular strength, balance, and gait ability were measured before and after the 5-week training. To assess for muscular strength, a digital muscle tester was used to measure hip flexor, knee extensor, and dorsiflexor strength. To assess for balance, the Berg Balance Scale (BBS) and Timed Up and Go Test (TUG) was used. To assess for gait, the 10 meter walk test (10MWT) and Functional Gait Assessment (FGA) was used. Results: The BWSTT-BK group showed significantly improved muscular strength, balance, and gait according to BBS, TUG, 10MWT, FGA, and digital muscle testing scores compared to the BWSTT group (p<0.05). In addition, within-group comparison showed significant improvement in all variables (p<0.05). Conclusions: These findings suggest that BWSTT-BK results in more favourable outcomes for stroke patients. Therefore, BWSTT-BK may be useful for the recovery of gait ability of stroke patients.

Effect of Sensory Stimulation Type on Brain Activity in Elderly Persons with Mild Cognitive Impairment

  • Koo, Japung;Hwang, Hyunsook
    • 국제물리치료학회지
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    • 제10권1호
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    • pp.1700-1705
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    • 2019
  • Background: Mild cognitive impairment (MCI) is also called as aging related memory damage. Decreased cognitive function due to aging is known to be associated with the frontal lobe. Alpha wave is generated in the dominance in the frontal lobe or a wide range of regions in the brain, it should be doubted that the brain function might be degraded. Objective: To determine the effect of sensory stimulation type on learning and brain activity pattern of elderly persons with MCI. Design: Randomized Controlled Trial (single blind) Methods: Twenty elderly persons aged more than 65 with MCI were randonmized to simultaneous visual/auditory stimulation group (SVASG) and or auditory stimulation group (ASG). Ten peoples were assigned to each group and lectroencephalogram test was performed to individuals. In the electroencephalogram test, electroencephalography of prior to sensory stimulation, and during sensory stimulation were measured to compare brain activity pattern according to the study groups and measurement period. Results: The relative alpha power due to a sensory stimulation type showed that the SVASG significantly decreased in the left frontal lobe and the left parietal lobe statistically compared to those of the ASG while sensory stimulation was given (p<.05). The relative beta power due to a sensory stimulation type showed that the SVASG significantly increased in the left and right frontal lobes, the left and right parietal lobes, and the left temporal lobe statistically compared to those of the ASG while sensory stimulation was given (p<.05). Conclusions: Electroencephalographic analysis showed that the type of sensory stimulation can affect the brain activity pattern. However, the effects were not studied that which brain activity pattern help to improved cognitive function of elderly persons with mild cognitive impairment.

Inferior alveolar nerve block by intraosseous injection with Quicksleeper at the retromolar area in mandibular third molar surgery

  • Sovatdy, Sam;Vorakulpipat, Chakorn;Kiattavorncharoen, Sirichai;Saengsirinavin, Chavengkiat;Wongsirichat, Natthamet
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제18권6호
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    • pp.339-347
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    • 2018
  • Background: There are many techniques of inferior alveolar nerve block injection (IANBI); one among them is the computer-assisted intraosseous injection (CAIOI). Here we aim to evaluate the effectiveness of CAIOI with $Quicksleeper^{(R)}$ in mandibular third molar surgery. Methods: This study is a clinical, single-blind, randomized, split-mouth, controlled trial including 25 patients (10 males and 15 females, mean age 21 years). The patients underwent surgical removal of bilateral mandibular third molars with two different IANBI techniques. One side was injected using $Quicksleeper^{(R)}$, and the other side was injected using a conventional IANBI. Both techniques used one cartridge (1.7 ml) of 1:100,000 epinephrine 4% articaine. A supplementary injection was used if necessary. All volumes of anesthetic agent used were recorded. Statistical analysis was performed using paired t-test and Wilcoxon test. Results: This research showed that CAIOI has faster onset and shorter duration of action than IANBI (P < 0.05). The pain was similar in both techniques. In the CAIOI group, one-third of the cases could be completed without additional anesthesia. The remaining two-thirds required minimal supplementary volume of anesthesia. The success rates were 68% for CAIOI and 72% for IANBI, respectively. Conclusion: CAIOI is an advantageous anesthetic technique. It can be used as an alternative to conventional IANBI for mandibular third molar surgery.

초박형 미세전류패치 적용이 만성 허리통증 환자의 통증과 허리 가동성에 미치는 영향 (Effects of ultra-thin microcurrent patch application on pain and mobility in patients with chronic low back pain)

  • 황태연;박재철
    • 대한물리치료과학회지
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    • 제29권4호
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    • pp.86-95
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    • 2022
  • Background: The purpose of this study is to investigate the effect of ultra-thin microcurrent patch application on pain, tenderness, trunk flexion, and trunk extension in patients with back pain. Design: pretest-posttest design: single blind. Methods: Thirty men and women diagnosed with chronic back pain were classified into 15 microcurrent application groups and 15 placebo groups. Changes in pain were observed on a visual analog scale, tenderness was observed with a digital tenderness meter, and changes in trunk flexion and trunk extension angles were evaluated with a posture analyzer. The paired t-test was used to see the changes within each group before and one week after the experiment, and the independent t-test was used to see the change in the difference between the groups, and the significance level was 0.05. Results: In both the experimental group and the control group, there was a significant difference in pain within and between groups(p<0.05). In the experimental group, there were significant differences in the intra- and inter-group changes in the erector spinae muscle tenderness and low back pain disorder index(p<0.05). In the experimental group, there was a significant difference in the change in trunk flexion and extension within the group(p<0.05). Conclusion: In this study, it was confirmed that the application of ultra-thin microcurrent was effective for pain, tenderness, and movement of back extension in patients with low back pain. It is expected that it will be used as a basic data for microcurrent therapy and as a treatment method for improving the function of patients with back pain in the future.

InGaAlP 레이저 경피혈액조사가 정상성인의 심박변이도에 미치는 영향에 대한 임상적 연구(II) (A Clinical Study of InGaAlP Laser Transcutaneous Blood Irradiation on Heart Rate Variability in Healthy Adults (II))

  • 여진주;이태호;손동혁;형례창;이인환;장인수
    • 대한중풍순환신경학회지
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    • 제6권1호
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    • pp.9-16
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    • 2005
  • Objective : The heart rate variability is very useful indicator to study the function of the autonomic nervous system(ANS), and the physiologic signals can be observed based on the changes of the ANS of the heart. In order to assay the effects of the laser exposing to healthy subjects, the double blind test has been performed. Methods : This study included 62 healthy adults who have not any ANS disease and had normal sinus rhythm in electrocardiogram. The control group consisted of 31 subjects, laser group consisted of 31 subject. HRV was measured for 5 minutes before laser irradiation, sham and real laser irradiated for 30 minutes and than HRV remeasured for 5 minutes. Statistical significance was evaluated by independent T-test. Results : Mean HRV, Ln(VLF), Ln(HF), Ln(TP) of both groups at post-laser period decreased compared with that of the pre-laser period. Ln(LF) of both groups at post-laser period increased compared with that of the pre-laser period. LF/HF, SDNN of real laser group decreased and sham group decreased. Conclusions : There is no difference between two groups. The reason is presumed that all the studied subjects are healthy adults, and also the short and single transcutaneous laser irradiation would not influence upon changes of the ANS. The further study must be followed.

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Effects on Mechanical Properties, Joint Range of Motion, and Grip Strength of Forearm Muscles Depending on Wrapping Direction of the Floss Band

  • Ki Bum Jung;Seohui Kim;Yongwoo Lee
    • Physical Therapy Rehabilitation Science
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    • 제13권1호
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    • pp.95-105
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    • 2024
  • Objective: The purpose was to investigate changes in mechanical properties, range of motion, and grip strength of the forearm muscle in 13 students depending on the wrapping direction of the floss band. Design: A single-blind, crossover study Methods: Subjects were randomly assigned to the wrapping direction of the flossing band and then performed a concentric exercise of the wrist flexors using a Flex-Bar. Intervention A applied the flossing band in a right spiral direction, Intervention B applied the flossing band in a left spiral direction, and Intervention C performed the exercise alone. All subjects used their dominant right hand, and pre- and post-assessments were conducted between interventions. To analyze differences in changes between groups pre- and post-, all results were subjected to one-way ANOVA, followed by Scheffe's test as a post-hoc analysis. The paired samples t-test was used to analyze the difference between pre- and post-change within groups. Results: First, in the mechanical properties of the Flexor carpi ulnaris (FCU) muscle, interventions A and B significantly improved muscle tone and stiffness than intervention C (p<0.05), and intervention A showed a significant decrease in decrement (muscle elasticity) than intervention B (p<0.05). Second, interventions A and B showed significant improvement in grip strength than intervention C (p<0.05). Conclusions: The right spiral direction of the flossing band tended to increase the elasticity of the muscles compared to the left spiral direction. Therefore, in future studies, it is necessary to choose the direction of the flossing band to increase the elasticity of the muscles.

이압요법이 암환자의 불면증에 미치는 효능 : 무작위배정, 단일맹검, 위약대조군 연구 (Effect of Auricular Acupress Therapy on Insomnia of Cancer Patients : Randomized, Single Blinded, Placebo Controlled Trial)

  • 정인숙;김정선;유화승
    • 대한약침학회지
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    • 제13권2호
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    • pp.93-100
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    • 2010
  • Background: Auricular acupressure is one of the traditional health care treatments in oriental medicine. Approximately, 30~40% of the cancer patients have said to be suffering from insomnia and half of them having chronic and severe insomnia at the same time. Insomnia caused cancer patients feel more pain, fatigue, depression and anxiety and it sometimes let the power to have the best of cancer pull down. Objective: To investigate how effective the auricular acupressure treatment to cancer patients suffering from insomnia. Methods: We recruited participants from East-West Cancer Center of Daejeon University. Finally, of the people whose age range from 20 to 75, 12 patients who got less than 40 points from the score of Oh's sleeping score (OSS) were recruited. Single-blind, randomized pilot study was performed. The treatment group received auricular acupressure treatment (AAT) on active points and the control group had received sham acupressure treatment (SAT) for five times. Sleep parameters were checked by using OSS and numeric rating scale (NRS). We checked the scale everytime, both before and after treatment. We analyzed the data statistically by using independent T-test, paired T-test and analysis of variance (ANOVA) test. (p<0.05) Results: Twelve cancer patients participated in this pilot study and there was no significant difference between control and treatment group. Only 7 of them had completed the whole treatment process, 4 patients of AAT group and 3 participants of SAT. The OSS of AAT group had increased from $34.0{\pm}4.3$ to $39.5{\pm}3.1$ and that of SAT group had increased from $38.3{\pm}3.5$ to $40.0{\pm}0.0$. There was no significant difference between them. The NRS of AAT group had increased from $6.3{\pm}2.9$, $04.8{\pm}2.1$ and that of SAT group had increased from $7.0{\pm}1.0$ to $5.0{\pm}2.6$. No significant difference was observed between them. Conclusion: Although both groups did not show significant differences, most of the experimental participants showed increasing OSS and NRS after treatments. Significant participants' number will be needed in the next study.

Single buccal infiltration of high concentration lignocaine versus articaine in maxillary third molar surgery

  • Phyo, Hnin Ei;Chaiyasamut, Teeranut;Kiattavorncharoen, Sirichai;Pairuchvej, Verasak;Bhattarai, Bishwa Prakash;Wongsirichat, Natthamet
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제20권4호
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    • pp.203-212
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    • 2020
  • Background: This research evaluated the numbness produced by lignocaine at an equal or higher concentration than that of 4% articaine through a single point of injection for maxillary third molar surgery. This randomized double-blind study was conducted to compare the anesthetic efficiency of 4% lignocaine with that of 4% articaine in impacted maxillary third molar surgery using a single buccal infiltration alone. Methods: The study participants were 30 healthy patients requiring the bilateral surgical removal of symmetrically-positioned maxillary third molars. Using a split-mouth design, each patient randomly received buccal infiltration of 1.7 ml of 4% lignocaine and 1.7 ml of 4% articaine during two separate appointments. After 15 minutes of anesthetic injection, surgery was performed by the same surgeon using a consistent technique on both sides. Pinprick test pain scores of the buccal and palatal gingiva of the maxillary third molar after 10 minutes and 15 minutes latencies, pain scores during the surgery, the need for supplemental anesthesia, and patients' satisfaction with anesthetic efficiency were recorded. Surgery performed without supplemental anesthesia was categorized as successful. Results: The success rates of 4% lignocaine and 4% articaine (83.34% vs. 86.67%, P = 1.00) were not significantly different. Only 5 cases (4 cases in the articaine group and 1 case in the lignocaine group) reported mild pain and pressure sensation (NRS ≤ 1) on probing at the palatal side after 15 minutes of latency (P = 0.25). The pain scores of maxillary third molar surgery in the two groups were not significantly different (P > 0.05). Moreover, the statistical analysis confirmed the comparable patient satisfaction of two study groups (P = 0.284). Conclusion: This study provides evidence that single buccal infiltrations of 4% lignocaine and 4% articaine have comparable anesthetic efficacy and success rates for impacted maxillary third molar surgery. Both 4% lignocaine and 4% articaine can produce effective palatal anesthesia and pain control using buccal infiltration alone after 15 minutes of latency.

노인의 무릎관절 통증과 부종 감소에 대한 미네랄 테이핑과 표준 키네시오 테이핑의 효과 비교 (The Comparison of the Effects of Mineral Taping and Standard Kinesio Taping on Reduces Pain and Edema in Knee Joints)

  • 고결;문상호;배상덕;김정란;권병안
    • 디지털융복합연구
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    • 제18권8호
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    • pp.311-319
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    • 2020
  • 본 연구의 목적은 천연광물질 분말로 나염 처리된 미네랄 테이핑이 노인의 무릎관절 통증 및 부종에 미치는 영향에 대한 연구이다. 무릎 통증이 있는 40명의 노인을 미네랄 테이핑군 20명과 키네시오 테이핑군 20명으로 나누어 단일맹검 방식으로 무작위 배치하였다. 연구 기간은 2020년 4월 6일~2020년 4월 7까지 실시하였으며, 테이핑 부착 전과 후 그리고 1일 후에 시점 별 통증과 혈류를 조사하였다. 무릎 통증은 측정 시점별로 사후검사(F= 93.758, p<.001)와 1일 후 검사(F=93.758, p<0.001)에서 유의한 차이가 있었다. 부종에 대한 혈류검사에서는 측정 시점별로 사후검사(F= 48.648, p<0.001)와 1일 후 검사(F=35,427, p<0.001)에서 유의미한 차이가 나타났다. 각 군별 효과 검정결과(F=0.160, p>0.05)에서는 유의한 차이가 없는 것으로 나타났다. 그러나 1일 후 유지효과를 비교했을 때 키네시오 테이핑 군보다 미네랄 테이핑 군이 사후점수에서 우수한 것으로 나타났다. 추후 테이핑 부착 시간과 유지 기간을 늘리면 긍정적인 효과가 있을 것이라 추측한다. 본 연구의 결과는 향후 테이핑 소재 연구에 기여하리라 사료 된다.