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Advanced neuroimaging techniques for evaluating pediatric epilepsy

  • Lee, Yun Jeong
    • Clinical and Experimental Pediatrics
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    • v.63 no.3
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    • pp.88-95
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    • 2020
  • Accurate localization of the seizure onset zone is important for better seizure outcomes and preventing deficits following epilepsy surgery. Recent advances in neuroimaging techniques have increased our understanding of the underlying etiology and improved our ability to noninvasively identify the seizure onset zone. Using epilepsy-specific magnetic resonance imaging (MRI) protocols, structural MRI allows better detection of the seizure onset zone, particularly when it is interpreted by experienced neuroradiologists. Ultra-high-field imaging and postprocessing analysis with automated machine learning algorithms can detect subtle structural abnormalities in MRI-negative patients. Tractography derived from diffusion tensor imaging can delineate white matter connections associated with epilepsy or eloquent function, thus, preventing deficits after epilepsy surgery. Arterial spin-labeling perfusion MRI, simultaneous electroencephalography (EEG)-functional MRI (fMRI), and magnetoencephalography (MEG) are noinvasive imaging modalities that can be used to localize the epileptogenic foci and assist in planning epilepsy surgery with positron emission tomography, ictal single-photon emission computed tomography, and intracranial EEG monitoring. MEG and fMRI can localize and lateralize the area of the cortex that is essential for language, motor, and memory function and identify its relationship with planned surgical resection sites to reduce the risk of neurological impairments. These advanced structural and functional imaging modalities can be combined with postprocessing methods to better understand the epileptic network and obtain valuable clinical information for predicting long-term outcomes in pediatric epilepsy.

Aesthetic Characteristics of Face in the Late Joseon-dynasty's Beauty Paintings (조선후기 미인화에 표현된 얼굴의 미적 특성)

  • Lee, Hyun-Ok;Ku, Yang-Suk
    • Fashion & Textile Research Journal
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    • v.14 no.6
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    • pp.918-927
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    • 2012
  • This study identified the aesthetic characteristics of the face description in late Joseon Dynasty beauty paintings. A total of 24 beauty paintings were selected as representative of the late Joseon Dynasty genre of painting works. The paintings were analyzed by the shape, color, and physiognomy of beauty trends from the components of women's faces expressed in the works of artists. The results of this study showed that the shape of the face components expressed a round, curved and thin line. Colors were expressed through Obang-sack (a traditional Korean color). Also the physiognomy of the late Joseon Dynasty's women was soft, wise, economical and brilliant. A round-forehead meant that economical and virtuous housekeeper, thin crescent shaped eyebrows denoted women of wisdom and excellent sensitivity. Single long thin eyelids and implied a women of longevity. A round curved nose were eager tobe a wise mother and a good wife. Small concave lips were desired eagerly by gentle and intelligent women. A curve face implied a subjective women of insight and good memory. In conclusion, the late Joseon Dynasty beauty paintings expressed a traditional Korean beauty face and a modern baby face. The data are useful for the aesthetic standards of modern through meaning of Korean traditional beauty.

Development and Evaluation of Ultra-precision Desktop NC Turning Machine (초정밀 데스크탑 마이크로 NC 선반 개발 및 성능평가)

  • Ro, Seung-Kook;Park, Jong-Kweon;Park, Hyun-Duk;Kim, Yang-Keun
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.22 no.4
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    • pp.747-754
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    • 2013
  • This study introduces a recently designed desktop-sized NC turning system and its components. This machine is designed for the ultra-precise turning of parts with a diameter of 0.5-20 mm with minimum space usage for the machine. This study aims to achieve submicron-level accuracy of movements and good rigidity of the machine for precision machining using the desktop-sized machine. The components such as the main machine structure, air bearing servo spindle, and XZ stage with needle roller guides are designed, and the designed machine is built with a PC-based CNC controller. Its static and dynamic stiffness performances and positioning resolutions are tested. Through machining tests with single-crystal diamond tools, a form error less than $0.8{\mu}m$ and surface roughness (Ra) of $0.03{\mu}m$ for workpieces are obtained.

A Multi-Dimensional Thermal-Hydraulic System Analysis Code, MARS 1.3.1

  • Jeong, Jae-Jun;Ha, Kwi-Seok;Chung, Bub-Dong;Lee, Won-Jae
    • Nuclear Engineering and Technology
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    • v.31 no.3
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    • pp.344-363
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    • 1999
  • A multi-dimensional thermal-hydraulic system analysis code, MARS 1.3.1, has been developed in order to have the realistic analysis capability of two-phase thermal-hydraulic transients for pressurized water reactor (PWR) plants. As the backbones for the MARS code, the RELAP5/MOD3.2.1.2 and COBRA-TF codes were adopted in order to take advantages of the very general, versatile features of RELAP5 and the realistic three-dimensional hydrodynamic module of COBRA-TF. In the MARS code, all the functional modules of the two codes were unified into a single code first. Then, the source codes were converted into the standard Fortran 90, and then they were restructured using a modular data structure based on "derived type variables" and a new "dynamic memory allocation" scheme. In addition, the Windows features were implemented to improve user friendliness. This paper presents the developmental work of the MARS version 1.3.1 including the hydrodynamic model unification, the heat structure coupling, the code restructuring and modernization, and their verifications.their verifications.

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A design of FFT processor for EEG signal analysis (뇌전기파 분석용 FFT 프로세서 설계)

  • Kim, Eun-Suk;Shin, Kyung-Wook
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.11
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    • pp.2548-2554
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    • 2010
  • This paper describes a design of fast Fourier transform(FFT) processor for EEG(electroencephalogram) signal analysis for health care services. Hamming window function with 1/2 overlapping is adopted to perform short-time FFT(ST-FFT) of a long period EEG signal occurred in real-time. In order to analyze efficiently EEG signals which have frequency characteristics in the range of 0 Hz to 100 Hz, a 256-point FFT processor is designed, which is based on a single-memory bank architecture and the radix-4 algorithm. The designed FFT processor has been verified by FPGA implementation, and has high accuracy with arithmetic error less than 2%.

Feed forward Differential Architecture of Analog Parallel Processing Circuits for Analog PRML Decoder (아날로그 PRML 디코더를 위한 아날로그 병렬처리 회로의 전향 차동 구조)

  • Sah, Maheshwar Pd.;Yang, Chang-Ju;Kim, Hyong-Suk
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.8
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    • pp.1489-1496
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    • 2010
  • A feed forward differential architecture of analog PRML decoder is investigated to implement on analog parallel processing circuits. The conventional PRML decoder performs the trellis processing with the implementation of single stage in digital and its repeated use. The analog parallel processing-based PRML comes from the idea that the decoding of PRML is done mainly with the information of the first several number of stages. Shortening the trellis processing stages but implementing it with analog parallel circuits, several benefits including higher speed, no memory requirement and no A/D converter requirement are obtained. Most of the conventional analog parallel processing-based PRML decoders are differential architecture with the feedback of the previous decoded data. The architecture used in this paper is without feedback, where error metric accumulation is allowed to start from all the states of the decoding stage, which enables to be decoded without feedback. The circuit of the proposed architecture is simpler than that of the conventional analog parallel processing structure with the similar decoding performance. Characteristics of the feed forward differential architecture are investigated through various simulation studies.

A compact and low-power consumable device for continuous monitoring of biosignal (소형화 및 저전력소모를 구현한 실시간 생체신호 측정기 개발)

  • Cho, Jung-Hyun;Yoon, Gil-Won
    • Journal of Sensor Science and Technology
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    • v.15 no.5
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    • pp.334-340
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    • 2006
  • A compact biosignal monitoring device was developed. Electrodes for electrocardiogram (ECG) and a LED and silicon detector for photoplethysmogram (PPG) were used. A lead II type was arranged for ECG measurement and reflected light was measured at the finger tip for PPG. A single chip microprocessor (model ADuC812, Analog Device) controlled a measurement protocol and processed measured signals. PPG and ECG had a sampling rate of 300 Hz with 8-bit resolution. The maximum power consumption was 100 mW. The microprocessor computed pulse transit time (PTT) between the R-wave of ECG and the peak of PPG. To increase the resolution of PTT, analog peak detectors obtained the peaks of ECG and PPG whose interval was calculated using an internal clock cycle of 921.6 kHz. The device was designed to be operated by 3-volt battery. Biosignals can be measured for $2{\sim}3$ days continuously without the external interruptions and data is stored to an on-board memory. Our system was successfully tested with human subjects.

Improving CMD Areal Density Analysis: Algorithms and Strategies

  • Wilson, R.E.
    • Journal of Astronomy and Space Sciences
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    • v.31 no.2
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    • pp.121-130
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    • 2014
  • Essential ideas, successes, and difficulties of Areal Density Analysis (ADA) for color-magnitude diagrams (CMD's) of resolved stellar populations are examined, with explanation of various algorithms and strategies for optimal performance. A CMD-generation program computes theoretical datasets with simulated observational error and a solution program inverts the problem by the method of Differential Corrections (DC) so as to compute parameter values from observed magnitudes and colors, with standard error estimates and correlation coefficients. ADA promises not only impersonal results, but also significant saving of labor, especially where a given dataset is analyzed with several evolution models. Observational errors and multiple star systems, along with various single star characteristics and phenomena, are modeled directly via the Functional Statistics Algorithm (FSA). Unlike Monte Carlo, FSA is not dependent on a random number generator. Discussions include difficulties and overall requirements, such as need for fast evolutionary computation and realization of goals within machine memory limits. Degradation of results due to influence of pixelization on derivatives, Initial Mass Function (IMF) quantization, IMF steepness, low Areal Densities ($\mathcal{A}$), and large variation in $\mathcal{A}$ are reduced or eliminated through a variety of schemes that are explained sufficiently for general application. The Levenberg-Marquardt and MMS algorithms for improvement of solution convergence are contained within the DC program. An example of convergence, which typically is very good, is shown in tabular form. A number of theoretical and practical solution issues are discussed, as are prospects for further development.

Design and Implementation of Distributed In-Memory DBMS-based Parallel K-Means as In-database Analytics Function (분산 인 메모리 DBMS 기반 병렬 K-Means의 In-database 분석 함수로의 설계와 구현)

  • Kou, Heymo;Nam, Changmin;Lee, Woohyun;Lee, Yongjae;Kim, HyoungJoo
    • KIISE Transactions on Computing Practices
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    • v.24 no.3
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    • pp.105-112
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    • 2018
  • As data size increase, a single database is not enough to serve current volume of tasks. Since data is partitioned and stored into multiple databases, analysis should also support parallelism in order to increase efficiency. However, traditional analysis requires data to be transferred out of database into nodes where analytic service is performed and user is required to know both database and analytic framework. In this paper, we propose an efficient way to perform K-means clustering algorithm inside the distributed column-based database and relational database. We also suggest an efficient way to optimize K-means algorithm within relational database.

Development and Utilization of Digital Telesounder System (디지털 원격 어군 정보 관측시스템의 개발과 이용)

  • 황두진;김동수;백광흠;노천희;정기철
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2000.10a
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    • pp.602-605
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    • 2000
  • This paper describes the development and utilization of digital telesounder system. The digital telesounder system consists of two parts. The one is sea station part, which consist of power, single board computer, A/D converter, and RF modem. The two is land station part, which consist of RF modem, color display, memory system and printer. We obtained good results at the two times of sea experiments. The digital telesounder system is sufficiently good and clear to color display the information of fish school in setnet.

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