• 한국정보통신학회논문지
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• 제21권2호
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• pp.339-344
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• 2017

본 논문에서는 Early-late detector, Duty-rate modulator, 그리고 LSI(Lock Status Indicator)를 사용하여 작은 크기와 빠른 위상고정 시간을 갖는 위상고정루프를 제안하였다. 제안된 위상고정루프는 작은 용량을 가진 하나의 커패시터를 사용하게 됨으로써 칩의 크기를 결정하는 루프필터의 크기가 작아지게 되어 크기를 최소화 하였다. 기존의 전하펌프와 달리 2개의 전하펌프를 사용하여 하나의 커패시터를 사용하더라도 2차 루프필터를 사용 한 것과 같은 전압파형을 만들어 줌으로써 위상을 고정시킬 수 있다. 2개의 전하펌프는 UP, DN신호 위상의 빠르기를 감지해주는 Early-late detector와 일정한 비율의 파형을 만들어주는 Duty-rate modulator에 의해 제어된다. LSI회로를 사용함으로써 빠른 위상고정시간을 얻을 수 있다. 제안된 위상고정루프는 1.8V $0.18{\mu}m$ CMOS 공정을 사용하여 설계하였고, Hspice 시뮬레이션을 통해 회로의 동작을 검증하였다.

• Journal of Radiation Protection and Research
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• 제30권1호
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• pp.31-34
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• 2005

The article is devoted to the study of some hi-and tricyclic derivatives of aziridine as materials lot newindicators of ionizing radiation. To create high sensitive materials some aspects of photo induced ring opening processes in aziridine derivatives in ethanol solutions and in polymeric matrix were studied and two steps character of the processes investigated was established. Two types of radioindicators were suggested and preliminary tested. The new way of synthesis of radiochromic derivatives of aziridine was developed and series of target compounds synthesized.

• 한국의료질향상학회지
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• 제7권2호
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• pp.204-216
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• 2000

Background : There has been a concern that the quality of care provided to end-stage renal disease (ESRD) patients in the United States may not be as good as recommended. This paper illustrates a composite measure to assess, the quality of care received by ESRD patients undergoing in-center hemodialysis by incorporating outcomes for 4 major treatment areas. The 4 treatment areas are: dialysis treatments, anemia control, nutritional management, and blood pressure control. Methods : The major data source for the study was the United States Renal Data System (USRDS) Dialysis Morbidity and Mortality Study Wave 1 (DMMS-1) d Sixteen categories of a composite quality indicator were constructed by combining 4 dichotomous variables (16=2*2*2*2). representing the optimal vs. less than optimal level of outcome for each of the 4 treatment outcome measure respectively. Optimal outcome level for each treatment area was defined based on the recommendation from the National Kidney Foundation: (a) delivered dialysis doses (Kt/V) ${\geq}$ 1.2; (b) hematocrit level ${\geq}$ 30%; (c) serum albumin concentration ${\geq}$ 3.8g/dl ; and (d) blood pressure of <140 / <90mmHg. The 16 quality indicator were ranked according to their relative quality weights, which were estimated from its association with the relative risk of survival, adjusting for patient's baseline severity and dialysis facility characteristics. Results : Out of the entire sample of 2,179 patients, only 229 (10%) meet th recommended outcome levels for all 4 treatment areas. Overall, the study patients were distributed evenly over the 16 quality indicators, indicating a great variation in the quality of ESRD care. It appears that the rank of the 16 quality-indicators is driven by serum albumin concentration, suggesting that serum albumin concentration may be the most powerful predictor of ESRD patient survival among the 4 outcome measures. Conclusion : The developed quality indicator has the advantage of describin a range of care for dialysis patients and thus providing a more complete picture of care as compared to previous studies that have focused on only single or few components of the ESRD care.

• Journal of Microbiology and Biotechnology
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• 제26권6호
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• pp.1026-1034
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• 2016

In the current study, a total of 135 enterococci strains from different sources were screened for the presence of the enterocin-encoding genes entA, entP, entB, entL50A, and entL50B. The enterocin genes were present at different frequencies, with entA occurring the most frequently, followed by entP and entB; entL50A and L50B were not detected. The occurrence of single enterocin genes was higher than the occurrence of multiple enterocin gene combinations. The 80 isolates that harbor at least one enterocin-encoding gene (denoted "Gene⁺ strains") were screened for antimicrobial activity. A total of 82.5% of the Gene⁺ strains inhibited at least one of the indicator strains, and the isolates harboring multiple enterocin-encoding genes inhibited a larger number of indicator strains than isolates harboring a single gene. The indicator strains that exhibited growth inhibition included Listeria innocua strain CLIP 12612 (ATCC BAA-680), Listeria monocytogenes strain CDC 4555, Enterococcus faecalis ATCC 29212, Staphylococcus aureus ATCC 25923, S. aureus ATCC 29213, S. aureus ATCC 6538, Salmonella enteritidis ATCC 13076, Salmonella typhimurium strain UK-1 (ATCC 68169), and Escherichia coli BAC 49LT ETEC. Inhibition due to either bacteriophage lysis or cytolysin activity was excluded. The growth inhibition of antilisterial Gene⁺ strains was further tested under different culture conditions. Among the culture media formulations, the MRS agar medium supplemented with 2% (w/v) yeast extract was the best solidified medium for enterocin production. Our findings extend the current knowledge of enterocin-producing enterococci, which may have potential applications as biopreservatives in the food industry due to their capability of controlling food spoilage pathogens.

• Geomechanics and Engineering
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• 제13권5호
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• pp.861-879
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• 2017

Coal and gas outburst is a serious dynamic disaster that occurs during coal mining and threatens the lives of coal miners. Currently, coal and gas outburst is commonly predicted using single indicator and its critical value. However, single indicator is unable to fully reflect all of the factors impacting outburst risk and has poor prediction accuracy. Therefore, a more accurate prediction method is necessary. In this work, we first analyzed on-site impacting factors and precursors of coal and gas outburst; then, we constructed a Fisher discriminant analysis (FDA) index system using the gas adsorption index of drilling cutting ${\Delta}h_2$, the drilling cutting weight S, the initial velocity of gas emission from borehole q, the thickness of soft coal h, and the maximum ratio of post-blasting gas emission peak to pre-blasting gas emission $B_{max}$; finally, we studied an FDA-based multiple indicators discriminant model of coal and gas outburst, and applied the discriminant model to predict coal and gas outburst. The results showed that the discriminant model has 100% prediction accuracy, even when some conventional indexes are lower than the warning criteria. The FDA method has a broad application prospects in coal and gas outburst prediction.

• 한국경영과학회지
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• 제32권2호
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• pp.163-175
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• 2007

[ $ulcorner$ ]Cost-Effectiveness Analysis$\lrcorner$ has been wifely used to evaluate economic efficiency of R&D projects, but most of cost-effectiveness evaluation systems have some problems such as systematic method for setting and evaluating cost factors, estimation of single effect on each R&D project, and estimation of cross effects among R&D projects. To solve these problems, we have designed a new evaluation indicator called a $ulcorner$Cost-Cross Effect Integration Indicator$lrcorner$ including cross effects developed in this research. The major research findings are summarized as follows : (1) $ulcorner$Coist Estimation Model$lrcorner$, which estimates the cost factors divided into two classes of assembly product and system product and then integrates the total cost values, has been designed. (2) A new method for estimating parameters of cross effects among R&D projects has been developed. (3) $ulcorner$Cross Effects Estimation Model$lrcorner$ to estimate multi-effects and cross effects by completion time among several projects has been designed. (4) $ulcorner$Integration Estimation Indicator$lrcorner$ for setting priority on a project group has been extracted by combination of total cost value and total effect value.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2009년도 하계학술발표대회 논문집
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• pp.102-107
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• 2009

Window system is an essential component for lighting, ventilation and thermal environment in buildings. Moreover, as balcony extension in apartment houses become legalized, the performance requirements of window systems in balcony space are getting complicated. However, at this moment, five properties of the windows are used to represent the performance aspects of the system, including wind resistance, air tightness, water tightness, sound insulation, thermal resistance. And such single properties are not capable to express the performance of a space with the window systems in terms of performance concept. A performance analysis with wholistic approach is required to see the effect of the window system in built environment. Thus, performance-based approach should be established, which will be able to evaluate the goal/function and comfort of occupants/owners. As the first step to develop the performance indicator for the window systme for balcony space, this study conducts a survey to find the required performance aspects. A complete set of performance-based indicators will be developed with verification methods in the later stage of research.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2009년도 한국우주과학회보 제18권2호
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• pp.37.4-38
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• 2009

Rho et al.(2008) showed that the eccentricity parameter of a CME is an important indicator for forecasting CME geoeffectiveness. In this study we have tested a capability of the eccentricity parameter as an indicator of CME direction. For this work we considered 11 CMEs observed by both SOHO/LASCO and STEREO/SECCHI (2007-2008 from Temmer et al. 2009) coronagraphs. We have estimated earthward direction angles for these CMEs based on two different methods: (1) the eccentricity parameter from a single coronagraph SOHO/LASCO and (2) the triangulation technique using a pair of spacecrafts LASCO/STEREO-A and LASCO/STEREO-B. As a result, we have found that for 7 out of 11 CME events their direction angles are consistent with each other within $20^{\circ}$. This result demonstrates that the earthward direction based on the eccentricity parameter can be a good potential indicator for CME propagation direction.

• 한국철도학회논문집
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• 제12권2호
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• pp.315-320
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• 2009

본 연구에서는 단일기준을 활용한 화물취급역 평가의 대안으로서 다수의 기준을 활용한 평가방법을 제안하고자 한다. 다수의 기준을 활용한 평가에서는 각 성과지표에 대한 가중치가 필요하며 Charnes, Cooper, and Rhodes(1978)가 제안한 자료포락분석은 이러한 가중치를 결정하는 방법으로 사용될 수 있다. 본 연구에서는 353개 화물취급역의 발송규모, 발송수입, 도착규모, 도착수입 등을 성과지표로 사용하고 이들을 자료포락분석을 사용하여 다수의 성과지표를 동시에 모두 반영한 평가결과를 제시한다. 이러한 결과는 철도경영자 또는 철도정책담당자의 경영전략 또는 정책의사결정에 유용하게 사용될 수 있을 것이다.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제51권2호
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• pp.92-97
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• 2002

One of the important roles of a DNA chip is the capability of detecting genetic diseases and mutations by analyzing DNA sequence. For a successful electrochemical genotyping, several aspects should be considered including the chemical treatment of electrode surface, DNA immobilization on electrode, hybridization, choice of an intercalator to be selectively bound to double standee DNA, and an equipment for detecting and analyzing the output signal. Au was used as the electrode material, 2-mercaptoethanol was used for linking DNA to Au electrode, and methylene blue was used as an indicator that can be bound to a double stranded DNA selectively. From the analysis of reductive current of this indicator that was bound to a double stranded DNA on an electrode, a normal double stranded DNA was able to be distinguished from a single stranded DNA in just a few seconds. Also, it was found that the peak reduction current of indicator is proportional to the concentration of target DNA to be hybridized with probe DNA. Therefore, it is possible to realize a sim71e and cheats DNA sensor using the electrochemical measurement for genotyping.