• Computers and Concrete
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• v.23 no.3
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• pp.171-188
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• 2019

This study proposed a new and efficient 2D damage-plasticity model within the framework of Isogeometric analysis (IGA) for the geometrically nonlinear damage analysis of concrete. Since concrete exhibits complicated material properties, two internal variables are introduced to measure the hardening/softening behavior of concrete in tension and compression, and an implicit gradient-enhanced formulation is adopted to restore the well-posedness of the boundary value problem. The numerical results calculated by the model is compared with the experimental data of three benchmark problems of plain concrete (three-point and four-point bending single-notched beams and four-point bending double-notched beam) to illustrate the geometrical flexibility, accuracy, and robustness of the proposed approach. In addition, the influence of the characteristic length on the numerical results of each problem is investigated.

• Geomechanics and Engineering
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• v.18 no.2
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• pp.111-119
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• 2019

Due to certain geological characteristics (high thickness, rocky properties), some underground coal mines require the use of explosives. This paper explores the effects of fragmentation of different decks detonated simultaneously in a single borehole with the use of numerical analysis. ANSYS/LS-DYNA code was used for the implementation of the models. The models include an erosion criterion to simulate the cracks generated by the explosion. As expected, the near-borehole area was damaged by compression stresses, while far zones and the free surface of the boundary were subjected to tensile damage. With the increase of the number of decks in the borehole, different changes in the fracture pattern were observed, and the superposition effects of the stress wave became evident, affecting the fragmentation results. The superposition effect is more evident in close distances to the borehole, and its effect attenuates when the distance to the borehole increase.

• Journal of the Semiconductor & Display Technology
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• v.20 no.1
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• pp.59-63
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• 2021

Upper electrode is one of core parts using plasma etching process at semiconductor. The purpose of this study is to analyze effects of cutting conditions for mechanical machining of silicon upper electrode. For this research, surface roughness of machined workpiece and depth of damage inside of silicon electrode are experimented and analyzed and different values of feed rate and depth of cut are applied for the experiments. From these experiments, it is verified that the surface roughness and internal damaged layer get worse according to take more fast feed rate. In conclusion, cutting condition is very important factor for machining. Results of this study can use to develop various parts which are made from single crystal silicon and affect various benefits to the semiconductor industry for better productivity.

• Journal of Microbiology and Biotechnology
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• v.31 no.2
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• pp.171-180
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• 2021

Caffeine, a methylxanthine analog of purine bases, is a compound that is largely consumed in beverages and medications for psychoactive and diuretic effects and plays many beneficial roles in neuronal stimulation and enhancement of anti-tumor immune responses by blocking adenosine receptors in higher organisms. In single-cell eukaryotes, however, caffeine somehow impairs cellular fitness by compromising cell wall integrity, inhibiting target of rapamycin (TOR) signaling and growth, and overriding cell cycle arrest caused by DNA damage. Among its multiple inhibitory targets, caffeine specifically interacts with phosphatidylinositol 3-kinase (PI3K)-related kinases causing radiosensitization and cytotoxicity via specialized intermediate molecules. Caffeine potentiates the lethality of cells in conjunction with several other stressors such as oxidants, irradiation, and various toxic compounds through largely unknown mechanisms. In this review, recent findings on caffeine effects and cellular detoxification schemes are highlighted and discussed with an emphasis on the inhibitory interactions between caffeine and its multiple targets in eukaryotic microorganisms such as budding and fission yeasts.

• Current Optics and Photonics
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• v.7 no.5
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• pp.511-517
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• 2023

Pipelines play an important role in urban water supply and drainage, oil and gas transmission, etc. This paper presents a technique for pattern recognition of fiber optic vibration signals collected by a distributed vibration sensing (DVS) system using a deep learning residual network (ResNet). The optical fiber is laid on the pipeline, and the signal is collected by the DVS system and converted into a 64 × 64 single-channel grayscale image. The grayscale image is input into the ResNet to extract features, and finally the K-nearest-neighbors (KNN) algorithm is used to achieve the classification and recognition of pipeline damage.

• Journal of Energy Engineering
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• v.21 no.3
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• pp.243-248
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• 2012

In this study, The report analysed the characteristics of power drop and damage of surface in solar cell through high temperature and humidity test. The solar cells were tested during the 1000hr in $85^{\circ}C$ temperature and 85% humidity conditions, that excerpted standard of PV Module(KS C IEC-61215). An analysis of the cell surface through EL(Electroluminescence), the cell has partly change of surface in yearly. Single-crystalline Solar cell efficiency is decreased from 17.7% to 15.6% and decreasing rate is 11.9%. On the other hand, Poly-crystalline Solar cell efficiency is decreased from 15.5% to 14.0% and decreasing rate is 9.3%. A comparison of the fill factor for analysis of electro characteristic in yearly, Single-crystalline Solar cell efficiency is decreased from 78.7% to 78.1% and decreasing rate is 4.7%. On the other hand, Poly-crystalline Solar cell efficiency is decreased from 78.1% to 76.7% and decreasing rate is 1.8%. Single-crystalline has more bigger power drop than poly-crystalline by the silicon purity and silicon atom arrangement. Also, FF decreasing rate has more bigger drop than efficiency decreasing rate for the reason that the damage of surface by exterior environmental factor is the more influence in cell than other reason that is decreasing FF by damage of p-n junction.

• Journal of Radiation Protection and Research
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• v.27 no.3
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• pp.181-188
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• 2002

We investigated the effect of Paeonia japonica (PJ) on radiation-induced oxidative damage to macromolecules in vitro and in vivo. The PJ reduced the tail moment (TM) which was a marker of DNA strand break in single-cell gel electrophoresis (SCGE; comet assay) in the human peripheral blood lymphocytes. Lipid peroxidation in the liver of the ICR mouse, measured as malondialdehyde (MDA), was also reduced by PJ administration. Ethanol fraction of PJ was more effective than polysaccharide fraction of that on reduction of TM in SCGE and lipid peroxidation. Also, Their activities to scavenge DPPH radicals and hydroxyl radicals were observed in vitro, and the activities were due to its ethanol fraction. It is plausible that scavenging of flee radicals by PJ extract may have played an important role in providing the protection against the radiation-induced damage. These results indicated that Paeonia japonica might be a useful radioprotector, especially since it is a relatively nontoxic natural product.

• Environmental and Resource Economics Review
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• v.18 no.3
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• pp.431-455
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• 2009

This study estimates the WTP for the plan of solving deforestation due to limestone mining and calculates that damage cost using contingent valuation method. As the results of analysing a dichotomous choice CV data, the yearly mean WTP per household for the plan is 5,045 won(95% confidence interval : 3,729~6,360 won) in single bounded CV model and is 4,361 won(95% confidence interval : 3,710~5,012 won) in double bounded CV model. The damage cost of deforestation due to limestone mining can be estimated as 55.3% of WTP for the plan which is assigned to restoring the deforestation area to the original or similar alternative state. The average yearly deforestation cost of 1 ha due to limestone mining is reached 20.90 million won(95% confidence interval : 16.53~25.27 million won). And the asset value of that 1 ha damage is 160.02 million won(95% confidence interval : 126.56~193.49 million won). The fact is found that the damage cost of deforestation using replacement cost method is likely to be underestimated. The total damage cost of deforestation because of limestone mining in 3 cities (Donghae, Samcheok, Yeongwol) is 204.0 billion won(95% confidence interval : 161.4~246.7 billion won) which is composed of 26.5% for Donghae, 28.9% for Samcheok, and 44.6% for Yeongwol according to the damage size of deforestation due to limestone mining in 3 cities.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.34 no.5
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• pp.509-517
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• 2008

DNA damage accumulates in cells as a result of exposure to exogenous agents such as benzopyrene, cigarette smoke, ultraviolet light, X-ray, and endogenous chemicals including reactive oxygen species produced from normal metabolic byproducts. DNA damage can also occur during aberrant DNA processing reactions such as DNA replication, recombination, and repair. The major of DNA damage affects the primary structure of the double helix; that is, the bases are chemically modified. These modification can disrupt the molecules'regular helical structure by introducing non-native chemical bonds or bulky adducts that do not fit in the standard double helix. DNA repair genes and proteins scan the global genome to detect and remove DNA damage and damage to single nucleotides. Direct reversal of DNA damage, base excision repair, double strand break. DNA repair are known relevant DNA repair mechanisms. Four different mechanisms are distinguished within excision repair: direct reversal, base excision repair, nucleotide excision repair, and mismatch repair. Genetic variation in DNA repair genes can modulate DNA repair capacity and alter cancer risk. The instability of a cell to properly regulate its proliferation in the presence of DNA damage increase risk of gene mutation and carcinogenesis. This article aimed to review mechanism of excision repair and to understand the relationship between genetic variation of excision repair genes and head and neck cancer.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.2D
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• pp.243-248
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• 2008

Moisture damage of asphalt pavements can usually occur because of the loss of adhesion and cohesion between the asphalt binder and aggregate in the asphalt mixture due to presence of water. And this is one of the causes that is effect on the main distress of asphalt pavement. The objective of this study is to find out moisture damage characteristics of asphalt pavement. Effects of this study changes of the material properties and resistance characteristics of moisture damage on the asphalt mixtures under various temperatures and repeated immersion using indirect tensile test and modify Lottman test were evaluated during this study. The asphalt mixtures were produced using straight asphalt binder, SBS modified asphalt binder and aggregates. The material properties (resilient modulus, indirect tensile strength, failure energy and $DCSE_f$) of the asphalt mixtures were generally decreased with increasing to moisture damage caused by the number of repeated immersion. The decrease ratios of material properties by repeated immersion on SBS modified asphalt mixtures were lower than those of straight asphalt mixtures at all three test temperatures. As a conclusion, current criterion for evaluation moisture damage of asphalt mixtures is difficult for using distinction standard because of the limited evaluation criterion with one time immersion and single material property. Based on this research, to evaluate long term moisture damage on asphalt mixtures, material property tests of various kinds with repeated immersion test are considered.