• Journal of Microbiology and Biotechnology
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• 제16권8호
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• pp.1174-1179
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• 2006

The wild-type Corynebacterium glutamicum ATIC 13032 and Corynebacterium glutamicum ATTC 13032 lysC S301Y, exhibiting a deregulated aspartokinase, were compared concerning growth, lysine production, and intracellular carbon fluxes. Both strains differ by only one single nucleotide over the whole genome. In comparison to the wild-type, the mutant showed significant production of lysine with a molar yield of 0.087 mol (mol glucose$^{-1}$) whereas the biomass yield was reduced. The deregulation of aspartokinase further led to a global rearrangement of carbon flux throughout the whole central metabolism. This involved an increased flux through the pentose phosphate pathway (PPP) and an increased flux through anaplerosis. Because of this, the mutant revealed an enhanced supply of NADPH and oxaloacetate required for lysine biosynthesis. Additionally, the lumped flux through phosphoenolpyruvate carboxykinase and malic enzyme, withdrawing oxaloacetate back to the glycolysis and therefore detrimental for lysine production, was increased. The reason for this might be a contribution of malic enzyme to NADPH supply in the mutant in the mutant. The observed complex changes are remarkable, because they are due to the minimum genetic modification possible, the exchange of only one single nucleotide.

• 한국주거학회논문집
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• 제25권2호
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• pp.1-9
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• 2014

This study investigates supply patterns and residential characteristics of the Urban-type Housing in Seoul. There have been 3,336 buildings and 71,790 housing units approved until the end of 2012. One-room apartments and small units less than 30 $m^2$ of residential area amount to 81% and 82% of total units, respectively. Major findings are as follows. First, single- and two-person households less than 30 years of age are mostly lived in the housing. Respondents are mainly professional and white-collar (43%) and service and sales workers (27%). Most of them are mid-income classes (67%), which is twice more than that of single- and two-person households in Seoul. They pay 672 thousand won in rent more than average rent of mid-income class. The rent to income ratios are 29.9% for single households and 24.5% for two-person households, which are higher than that of mid-income bracket. Third, their satisfaction level is relatively high in internal environment and access to public service facilities, but not in external environment and community service facilities. They are satisfied with security and daylight, walking and safety, access to public transport and parking space, but not with noise and vibration, natural environment, access to park and cultural and sports facilities, and most community service facilities. It is necessary to reexamine the articles of deregulation and prepare design standards while considering different housing and locational types.

• 한국가정과교육학회지
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• 제13권2호
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• pp.1-14
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• 2001

The purpose of this study was to find out and advocate the intake of vitamin A and C rich foods in Korean people. Forty kinds of vitamin A and C rich foods were selected by the vitamin quantity in 100g edible portion. in single serving size. and by the 1997 national food supply data. The results were summarized as follows. 1. The vitamin A rich foods 1) The food sources of vitamin A presented in the middle and high school home economics textbooks were liver. egg/egg yolk. milk/dairy products. and green and yellow vegetables. etc. 2) The vitamin A rich foods by 100g edible portion ere in order of red pepper(dried). laver(dried). carrot. meat edible viscera. eel. etc. And the vitamin A rich foods by the vitamin A content in single serving size were in order of carrot. eel. meat edible viscera. water shield. red pepper(dried). etc. 3) The vitamin A suppling foods according to the 1997 national food supply data were in order of red pepper(dried). meat edible viscera. laver. carrot. etc. The green and yellow vegetables. fish and shellfish. and seaweeds were the most important sources of vitamin A in Korean. 2. The vitamin C rich foods 1) The food sources of vitamin C presented in the textbooks of middle and high school were strawberry. citrus fruits. and vegetables such as spinach. chinese cabbage. radish. crown daisy. etc. 2) The vitamin C rich foods on the basis of the vitamin C content in 100g edible portion were in order of sweet pepper. goose berry. citron. strawberry. water shield. etc. And the vitamin C rich foods by the quantity in single serving size were in order of strawberry. goose berry. citron. sweet pepper. lemon. etc. 3) The vitamin C suppling foods according to the 1997 national food supply data were in order of chinese cabbage. radish. citrus fruits. strawberry. etc. Not only vegetables and fruits but also seaweeds like dried laver and sea mustard were the most important source of vitamin C in korean.

• Environmental Engineering Research
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• 제25권2호
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• pp.251-257
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• 2020

This study was performed to verify the possibility of nitrification and denitrification in a single reactor. In batch type experiment, optimal point of experimental conditions could be found by performing the experiments. When supply location of microbubbles was located at half of width of the aeration tank and operating pressure of 0.5 bar, it was possible for zones in the aeration tank to be separated into anoxic and aerobic by controlling air suction rate according to operating pressure of the generator. To be specific, the concentration of dissolved oxygen (DO) in zone 1 and 2 of the aeration tank could be maintained as less than 0.5 mg/L. Also, in the case of concentration of oxygen in zone 3 and 4, the concentration of DO was increased up to 1.7 mg/L due to effects of microbubbles. In continuous flow type experiment based on the results of batch type experiments, the removal efficiency of nitrogen based on T-N was observed as 39.83% at operating pressure of 0.5 bar and 46.51% at operating pressure of 1 bar so it was able to know that sufficient air suction rate should be required for nitrification. Also, denitrification process could be achieved in a single reactor by using ejector type microbubble generator and organic matter and suspended solid could be removed. Therefore, it was possible to verify that zones could be separated into anoxic and aerobic and nitrification and denitrification process could be performed in a single reactor.

• 한국정보통신학회논문지
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• 제11권2호
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• pp.322-329
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• 2007

본 논문에서는 디지털 의료 영상 및 진단 분야 그리고 산업용으로도 활용 가능한 싱글 포톤 계수형 영상센서를 $0.18{\mu}m$ triple-well CMOS(Complementary Metal Oxide Semiconductor) 공정을 사용하여 설계하였다. 설계된 Readout 칩용 싱글 픽셀은 디지털 X-ray 이미지 센서모듈을 간단화 하기 위해 단일 전원전압을 사용하였으며, Preamplifier의 출력 전압인 signal voltage(${\Delta}Vs$)를 크게 하기 위해 Folded Cascode CMOS OP amp를 이용한 Preamplifier를 설계하였으며, 기존의 Readout 칩 외부에서 인가하던 threshold voltage를 Readout 칩 내부에서 생성해 줄 수 있도록 Externally Tunable Threshold Voltage Generator 회로를 새롭게 제안하였다. 그리고, Photo Diode에서 발생하는 Dark Current Noise를 제거하기 위한 Dark Current Compensation 회로를 제안하였으며, 고속 counting이 가능하고, layout 면적이 작은 15bit LFSR(Linear Feedback Shift Resister) Counter를 설계하였다.

• KIEAE Journal
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• 제9권4호
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• pp.17-22
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• 2009

It is common to design the duct branches where to supply the required air flow for individual room in residential apartment house. However it is difficult to adjust the air volume adequately in small air duct branches in residential ventilation system. The purpose of this study is to figure out the performance of Multidrop chamber coupling system for the residential ventilation system. The experiments were designed to simulate apartment of $84m^2$ and established multidrop chamber duct and general duct on the ceiling of the apartment. Distribution performance of air supply rate were evaluated in this experiments. As a result, distribution performance of air supply rate in the general duct is different from designed air supply rate by about 35% ~ 50% and about 10% in the multidrop chamber system. In additional the sound insulation performance of the multidrop chamber system decreased about 20% compared with general duct system. Therefore, the multidrop chamber system is considered to satisfy proper air supply rate of each room and to improve the sound insulation performance in apartment Houses.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2003년도 추계종합학술대회
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• pp.758-761
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• 2003

전원장치의 소형화 핵심기술인 반도체 스위칭 기술을 이용하여 단일 전원을 사용하는 소형, 경량화 전자기기에 적합한 5 V/500 mA급 트랜스리스형 파워 모듈(transless type power module)을 설계하였다. 파워 모듈은 강압형 chopper 방식을 이용한 스위칭회로, 제어회로, 전압검출회로, 그리고 정전압 회로 둥으로 구성되어 있으며, 하이브리드-집적회로형(hybrid-IC type)으로 제작되었다. 본 연구에서 설계한 스위칭 레귤레이터 전원회로는 5 V/500 mA급 트랜스리스형 파워 모듈의 전기적 특성을 만족하였다.

• Industrial Engineering and Management Systems
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• 제13권2호
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• pp.129-147
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• 2014

This study proposes an optimal operational policy for a green supply chain (GSC) where a retailer pays an incentive for collection of used products from customers and determines the optimal order quantity of a single product under uncertainty in product demand. A manufacturer produces the optimal order quantity of product using recyclable parts with acceptable quality levels and covers a part of the retailer's incentive from the recycled parts. Here, two scenarios for the product demand are assumed as: the distribution of product demand is known, and only both mean and variance are known. This paper develops mathematical models to find how order quantity, collection incentive of used products and lower limit of quality level for recycling affect the expected profits of each member and the whole supply chain under both a decentralized GSC (DGSC) and an integrated GSC (IGSC). The analysis numerically compares the results under DGSC with those under IGSC for each scenario of product demand. Also, the effect of the quality of the recyclable parts on the optimal decisions is shown. Moreover, supply chain coordination to shift the optimal decisions of IGSC is discussed based on: I) profit ratio, II) Nash bargaining solution, and III) Combination of (I) and (II).

• 한국전자통신학회논문지
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• 제16권3호
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• pp.437-442
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• 2021

본 연구는 우주 인증용 대전자전중계기용 전원공급기의 설계 및 구현에 대해 기술하였다. 위성버스의 PLDIU(Payload Distribution and Interface Unit)와 전원공급기의 인터페이스를 제시하였고, 우주환경에 대한 WCA(Worst Case Analysis)를 통하여 SEU(Single Event Upset) 등의 발생에 대한 회로 오동작 가능성을 최소화 시켰다. 발사환경 시 발생하는 진동 및 우주 방사능에 의한 TID(Total Ionizing Dose)에 대한 시뮬레이션을 통해 신뢰성 있는 전원공급기를 설계하였으며, 제작 후 우주환경시험을 통하여 해당 구성품에 대한 환경 시험 규격에 만족함을 확인하였다.

• 산업공학
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• 제16권3호
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• pp.280-290
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• 2003

Many firms are trying to optimize their production and distribution functions separately, but possible savings by this approach may be limited. Nowadays, it is more important to analyze these two functions simultaneously by trading off the costs associated with the whole. In this paper, I treat a production and distribution planning problem for single-period inventory products comprised of a single production facility and multiple customers, with the aim of optimally coordinating important and interrelated decisions of production sequencing and vehicle routing. Then, I propose a hybrid genetic algorithm incorporating several local optimization techniques, HGAP, for integrated production-distribution planning. Computational results on test problems show that HGAP is effective and generates substantial cost savings over Hurter and Buer's decoupled planning approach in which vehicle routing is first developed and a production sequence is consequently derived. Especially, HGAP performs better on the problems where customers are dispersed with multi-item demand than on the problems where customers are divided into several zones based on single-item demand.