• Interdisciplinary Bio Central
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• v.2 no.2
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• pp.4.1-4.6
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• 2010

The most common type of microarray experiment has a simple design using microarray data obtained from two different groups or conditions. A typical method to identify differentially expressed genes (DEGs) between two conditions is the conventional Student's t-test. The t-test is based on the simple estimation of the population variance for a gene using the sample variance of its expression levels. Although empirical Bayes approach improves on the t-statistic by not giving a high rank to genes only because they have a small sample variance, the basic assumption for this is same as the ordinary t-test which is the equality of variances across experimental groups. The t-test and empirical Bayes approach suffer from low statistical power because of the assumption of normal and unimodal distributions for the microarray data analysis. We propose a method to address these problems that is robust to outliers or skewed data, while maintaining the advantages of the classical t-test or modified t-statistics. The resulting data transformation to fit the normality assumption increases the statistical power for identifying DEGs using these statistics.

• Journal of applied mathematics & informatics
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• v.5 no.1
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• pp.263-268
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• 1998

This paper proposes the two-sample comparison us-ing sign test based on ranked-set sample(RSS). We investigate the asymptotic properties of the proposed test statistic and compare the asymptotic relative efficiencies of the proposed test statistic with re-spect to Mann-Whitney-Wilcoxon test statistic based on RSS and Mann-Whitney-Wilcoxon test statistic based on the simple random sample(SRS).

• Journal of Korean Society for Quality Management
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• v.27 no.2
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• pp.143-151
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• 1999

In this thesis, a new test statistic is proposed for testing exponentiality against New Better than Used (NBU) alternatives. Our test statistic, which is based on a quadratic function of the order statistics from the sample, is readily applied in the case of small sample. Also, Our test statistic is more simple than the test statistic of Hollander and Proschan(1972).

• 한국전산유체공학회:학술대회논문집
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• 2000.05a
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• pp.184-190
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• 2000

A well-known pressure correction method, a SIMPLE algorithm is extended to treat compressible flows. Collocated grids are used and density is linked to pressure via an equation of state. The influence of pressure on density in the case of compressible flows is implicitly incorporated into the extended SIMPLE algorithm. The first-order Upwind and high-order Quick scheme are compared with respect to an accuracy and convergence time at all speeds. The extended method is verified on a number of test cases and the results we compared with other numerical results available in the literature. The calculated results show that the Quick scheme improves accuracy at all speed and also reduces the calculation time at supersonic flows, compared with the Upwind scheme.

• Journal of computational fluids engineering
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• v.5 no.2
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• pp.1-8
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• 2000

A well-known pressure correction method, a SIMPLE algorithm, is extended to treat compressible flows. Collocated grids are used and density is linked to pressure via an equation of state. The influence of pressure on density in the case of compressible flows is implicitly incorporated into the extended SIMPLE algorithm. The first-order Upwind and high-order Quick scheme are compared with respect to an accuracy and convergence time at all speeds. The extended method is verified on a number of test cases and the results are compared with other numerical results available in the literature. The calculated results show that the Quick scheme improves accuracy at all speed and also reduces the calculation time at supersonic flows, compared with the Upwind scheme.

• Fire Science and Engineering
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• v.6 no.1
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• pp.17-22
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• 1992

We have derived the general transfer equation for governing the continuity, energy transfer, mass and momentum transfer, and turbulent energy dissipation rate within the fire compartment which has the 800t fire source at the center of the floor. The governing transfer equations have been descretized using the finite volume approach and numerically experimented under the SIMPLE algorithm. In order for the SIMPLE algorithm approach to be physically reliable, the test results are compared with those of Morita's SOR Method using Conjugate Residual Method and found to be close to physical values though the computational convergence time still remains to be upgraded. The treatment of source terms in the system of finite difference equations has been critical in order to converge the governing equations within the appropriate time steps. The criteria of convergence allowance for the whole domain have been checked and the sudden change of the non-linear effects from the source term have been avoided. The criteria has been allowed to be for 5$\times$10$^{-5}$ .

• Korean Journal of Animal Reproduction
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• v.7 no.2
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• pp.8-26
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• 1983

Various early pregnancy diagnostic methods have been developed in order to improve the reproductive efficiency in cow, mare, mule, sow, sheep, goat, dog, cat, rabbit, buffalo, camel, elephant, monkey, deer, lion, coipus and guinea pig. These methods include abdominal swelling, abdominal palpation, esturs cylce detection, Lupin test, gonadotropin assay, colostrum injection test, sperm motility assessment, cervical mucus viscosity test, Kaber chromagens method, estrogen test, A Scheim-Zond다 test, spectrophotometric detection of estrogen in urine and feces, boric acid crystraline formation test in urine, oxytocin injection test, diamino-oxidase test, PMSG HA test, behaviour test, Simolus iodine detection test, detection of tryptophane in urine, x-ray method, Cuboni and Lunaas method, vaginal biopsy method, Friedmann Schneider diagnostic method, electrode method, barium chloride detection method, ECG, Doptone method, ultrasound method, ultrasound scanning method, LDH method, rectal palpation method, CL palpation method, radioautography, serum creatine test, serum globulin test, chlormadine method, CAP method, Medata Do, pp.ers method, body fluid test, Plasma oCS detection method, ERIA, LHRH method, negative latex cogulation test and oestrone sulphate detection method. The most reliable methods with high a, pp.icability to farm animals such as sheep, mare, sow and cow are rectal palpation, ultrasound method and hormonal assay in blood and milk. However, they require complicated laboratory works for the early diagnosis of pregnancy and in most cases, the simple and economical methods which are described up to now need a long period of time after conception. Generally, it is possible to detect pregnancy after one estrus cycle, even though it varies depending on the species of animals. For improvement of the reproductive efficiency, it is required to develop a more accurate, economical, simple and early detectable method. It is anticipated that the result of a study on the detection method of EPF(early pregnancy factor) would be a, pp.icable to various animals within 6 hours after conception.

• Korean Business Review
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• v.20 no.2
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• pp.1-13
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• 2007

The purpose of this study is to investigate a simple present value model Involving earnings (i.e., the earnings discount model) that presumes a relationship between stock prices and earnings. The model suggests a simple linear equilibrium relationship between stock prices and earnings. The tests for cointegration render strong support for the cointegration hypothesis between stock prices (Pt) and earnings (Xt) even at the one-percent significance level. The tests are based on residuals from a cointegrating regression of Pt on Pt+l + Xt. This suggests that there is a stable long-nu equilibrium relationship between stock prices and earnings. The results of the tests lead to the acceptance of the present value model of stock prices involving earnings.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2002.04a
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• pp.410-415
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• 2002

A winding bend rig is designed to overcome the drawbacks of the conventional bend rig for measuring springback ratio of a strip or plate. Using the present bend rig, springback ratios are measured and they are compared with ones that obtained by using simple beam theory and tensile test. Theoretically, there should be no difference between the two values as far as the simple beam theory holds true for the bending test. But, within the scope of our tests, there is a difference of 5% between the two values since the specimen under bend test is subjected to a transverse shear force and friction force on the surface of the specimen.

• Journal of the Korean Statistical Society
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• v.18 no.2
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• pp.125-134
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• 1989

This paper presents optimum simple step-stress accelerated life test plans for the case where the test process is observed periodically at intervals of the same length. Two types of failure data, periodically observed complete data and periodically observed censored data, are considered. An exponential life distribution with a mean that is a log-linear function of stress, and a cumulative exposure model for the effect of changing stress are assumed. For each type of data, the optimum test plan which minimizes the asymptotic variance of the maximum likelihood estimator of the mean life at a design stress is obtained and its behaviors are studied.