• Proceedings of the KSR Conference
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• 2009.05a
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• pp.322-330
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• 2009

Traffic congestions in local cities have been getting worse since 1990s, so many local governments have considered the introduction of an LRT system. So far, there is no city operating the LRT due to social environments, financial reasons, feasibility and so on. But still many cities have examined LRT or started the construction. Until now, more than 30 cities are constructing LRT or planning the introduction of LRT and it becomes 96 routes, approximately 700km. With the support of MLTM, KRRI has developed automatic LRT system with rubber-wheels, K-AGT as a result of "LRT system technology development project" from 1999 to 2005 by investing 50.32 billion wons(the public 37, the private 13.32) and finished running durability test of 100,000km at Kyeong-san test line. Currently, two trains, coupled two cars respectively have running and signaling tested. K-AGT was appointed to supply for an extension line at Busan Subway Line 3(Minam-Anpyeong section) with 17 trains(six-unit car) 102 cars. However, except for Minam-Anpyeong section, other cities such as Uijeongbu, Yongin, Daegu(Line 3) and Kwangmyeong decided to use the foreign systems, not to use the product, a result of national R&D project. This results in a huge waste of foreign currency and it is expected to require much additional cost for maintenance. If local governments use the products of national R&D projects, many national benefits such as reducing imports and protecting home industries could be expected, therefore in this paper, some plans to encourage to use products of national R&D projects were dealt with.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.12 no.1
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• pp.201-210
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• 2012

Now, there are many mobile nodes are efficient and stable when they move to operate with variety techniques have emerged.Recently, there is a growing interest about PMIPv6(Proxy Mobile IPv6) and, in this proposal of essay is the based on the way to mobility support system will stand on the basis from PMIPv6 network to NEMO(Network Mobility). PMIPv6 is mobility support system from single domain, it actual network is composed with nested in a multiple domain structural system. The proposed technique in the domain of two or more, the LMA(Local Mobility Anchor) communication between LMA(Local Mobility Anchor) and MAG(Mobile Access Gateway) of movable domain can increase performance by handover delay and signaling.

• Journal of the Korea Society of Computer and Information
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• v.12 no.5
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• pp.139-144
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• 2007

The mobile terminal's frequent changes to the access point introduce significant network overhead in mobile IP networks. To solve this problem, we introduce a hierarchical structure with consideration given to the dynamic value of neighbor scope in IP regional registration[1]. When a mobile terminal moves within the neighbor given by the scope value, it makes registration locally without registration with its home agent. We analyze the algorithm mathematically and show the numerical results. As a result, optimization of the scope value for the localized registration under the hierarchical structure makes the proposed scheme outperform the standard mobile IP protocol[2]. This can be explained from the fact that there is only local registration for terminal's movement within the scope region. Moreover, as the signaling cost for home agent increases, the proposed scheme becomes more advantageous.

• Proceedings of the KSR Conference
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• 2006.11b
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• pp.1454-1460
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• 2006

This paper assesses communication performance using a roaming simulator when roaming occurs between onboard and ground wireless communication devices for communication based train control system (CBTC). Generally, CBTC is defined as the system regularly collecting location and speed data from each train, transmitting distance information to a train, and optimizing train speed according to train performance. When a train is moving, roaming is also performed to continuously transmit and receive train control information between the ground controller and the train. To operate CBTC, packet loss rate should be less than 1%, roaming time less than 100ms during roaming. We developed a roaming simulator to check communication performance before installing ground and onboard equipments on actual wireless sections. The roaming simulator to be introduced in this paper is for roaming simulation before conducting CBTC field test, which is the project to develop Urban Rail Signaling System Standards, being conducted in KRRI. The simulation consists of one onboard wireless communication device and three ground wireless communication devices, and the roaming simulator estimate packet loss rate occurring during roaming process of the two devices. Therefore, if you use the roaming simulator before the field test, you can predict various problems to occur in actual environment and reduce time, cost and people necessary to resolve these problems.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39C no.11
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• pp.1078-1087
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• 2014

In the conventional centralized mobility management schemes, it can lead to single points of failure, occurrence of a bottleneck, since all data and control are concentrated on the mobility anchor which is located in home network. In the current research of distributed mobility management, it is doing research into distributed mobility management which is supported by distributed mobility anchors. Such schemes do not consider a failure of the mobility anchor. However, it could be an issue under tactical environment since it occur non-service problem due to anchor movement, maintenance, failure, etc. In this paper, we proposed new DMM scheme named T-DMM(Tactical-Distributed Mobility Management) which can support handover even if mobility anchor breaks down. From the numerical analysis, we evaluate signaling cost and handover latency.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38A no.4
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• pp.337-349
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• 2013

In this paper, we propose a new mobility management scheme, called i-FP(intelligent Fast PMIPv6). Our proposed i-FP scheme is addressed for solving the existing local mobility management problems from legacy frameworks. To move MN(Mobile Node) to other networks in one domain, i-FP employs three network entities which are extended from PMIPv6(Proxy Mobile IPv6), LMA(Local Mobility Anchor), MAG(Mobile Access Gateway) and MN. In i-FP, the three network entities can reduce the handover delay time of MNs. Also, i-FP uses an IP header swapping mechanism to avoid the traffic overhead and improve the throughput of network. To evaluate the performance of i-FP, we analyze our i-FP, HMIPv6(Hierarchical Mobile IPv6) and PMIPv6 which are legacy protocols of local mobility management in terms of various parameters. Finally, our i-FP scheme shows good performance(reduction of routing hops 10.2%, signaling costs 58.5% and handover delay 16.3%) than other network schemes for the total cost.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.1B
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• pp.1-7
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• 2008

In group location management, when a transportation system(TS) with multiple mobile subscribers(MSs) changes location area(LA), location management is performed by group location registration by TS, instead of individual location registrations by MSs. In previous works, although it is assumed that LA in group location management is the same as that in individual location management, it is not appropriate to assume the same sized LAs since MSs in a TS have different characteristics from MSs which are not in a TS from the aspect of the speed and aggregate call arrival rates. Thus, in this paper, we propose an efficient location management scheme based on individual and group location managements with different sized LAs, and the performance of the proposed scheme is analyzed from the aspect of signaling cost at the wireless interface. Results reveal that the proposed scheme outperforms the conventional scheme by selecting an appropriate sized LA for group location management.

• Journal of the Korea Society of Computer and Information
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• v.27 no.1
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• pp.157-166
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• 2022

In this study, The goal is to analyze the feasibility of introducing a Piggyback system that can reduce the time and cost incurred by transshipment work and improve the transportation speed when transporting complex cargo by rail. To this end, the feasibility analysis methodology is reviewed through domestic and international literature review. In order to quantitatively derive the feasibility analysis values, a transportation database was applied to develop a freight transport simulation model and a freight demand prediction model for major freight transport O-D routes with a transportation distance of 200 km or more. As a result of analyzing economic feasibility by setting the analysis period to 15 years on the premise that the Piggyback System will be introduced on major cargo transport O-D routes in 2025, the NPV value was positive and the B/C value was 1.18, indicating that the Piggyback system was economical. The proposed research method can be meaningful data for establishing transportation policies that can improve the competitiveness of railroad transportation.

• Food Science of Animal Resources
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• v.43 no.6
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• pp.1017-1030
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• 2023

Fetal bovine serum (FBS), which contains various nutrients, comprises 20% of the growth medium for cell-cultivated meat. However, ethical, cost, and scientific issues, necesitates identification of alternatives. In this study, we investigated commercially manufactured serum-free media capable of culturing Hanwoo satellite cells (HWSCs) to identify constituent proliferation enhancing factors. Six different serum-free media were selected, and the HWSC proliferation rates in these serum-free media were compared with that of control medium supplemented with 20% FBS. Among the six media, cell proliferation rates were higher only in StemFlex^TM Medium (SF) and Mesenchymal Stem Cell Growth Medium DXF (MS) than in the control medium. SF and MS contain high fibroblast growth factor 2 (FGF2) concentrations, and we found upregulated FGF2 protein expression in cells cultured in SF or MS. Activation of the fibroblast growth factor receptor 1 (FGFR1)-mediated signaling pathway and stimulation of muscle satellite cell proliferation-related factors were confirmed by the presence of related biomarkers (FGFR1, FRS2, Raf1, ERK, p38, Pax7, and MyoD) as indicated by quantitative polymerase chain reaction, western blotting, and immunocytochemistry. Moreover, PD173074, an FGFR1 inhibitor suppressed cell proliferation in SF and MS and downregulated related biomarkers (FGFR1, FRS2, Raf1, and ERK). The promotion of cell proliferation in SF and MS was therefore attributed to FGF2, which indicates that FGFR1 activation in muscle satellite cells may be a target for improving the efficiency of cell-cultivated meat production.

• Bulletin of the Korean Chemical Society
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• v.33 no.5
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• pp.1707-1714
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• 2012

Grb2 is an adapter protein involved in the signal transduction and cell communication. The Grb2 is responsible for initiation of kinase signaling by Ras activation which leads to the modification in transcription. Ligand based pharmacophore approach was applied to built the suitable pharmacophore model for Grb2. The best pharmacophore model was selected based on the statistical values and then validated by Fischer's randomization method and test set. Hypo1 was selected as a best pharmacophore model based on its statistical values like high cost difference (182.22), lowest RMSD (1.273), and total cost (80.68). It contains four chemical features, one hydrogen bond acceptor (HBA), two hydrophobic (HY), and one ring aromatic (RA). Fischer's randomization results also shows that Hypo1 have a 95% significant level. The correlation coefficient of test set was 0.97 which was close to the training set value (0.94). Thus Hypo1 was used for virtual screening to find the potent inhibitors from various chemical databases. The screened compounds were filtered by Lipinski's rule of five, ADMET and subjected to molecular docking studies. Totally, 11 compounds were selected as a best potent leads from docking studies based on the consensus scoring function and critical interactions with the amino acids in Grb2 active site.