• Journal of radiological science and technology
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• v.38 no.3
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• pp.253-259
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• 2015

The information of contrast media concentration on target organ is very important to get reduce the side effect and high contrast imaging. We investigated alternation of signal intensity as a function of the modality of Gd-based contrast media on spin echo and ultra short time echo (UTE) of T1 effective pulse sequence at 3T MRI unit. Gadoxetic acid, which is a MRI T1 contrast medium, was used to manufacture an agarose phantom diluted in various molarities, and sterile water and agarose 2% were used as the buffer solution for the dilution. The gold standard T1 calculation was based on coronal single section imaging of the phantom mid-point with 2D Inversion recovery spine-echo pulse sequence MR imaging for testing of phantom accuracy. The 1-2mmol/L and 7mmol/L was shown the maximum signal intensity on spin echo and UTE respectively. We confirm the difference of contrast media concentration which was shown the maximum signal intensity depending on the T1 effective pulse sequence.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.2A
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• pp.169-178
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• 2007

In this paper, we propose a signal structure and its optimum receiver to improve performance of SC-FDE(Single Carrier with Frequency Domain Equalization) system. Conventional SC-FDE systems have a drawback of power unbalance in frequency domain due to generation of pilot signals in time domain. The unbalanced power in frequency domain induces a channel estimation error and the performance of the receiver is degraded significantly. To overcome the drawback we apply CAZAC sequence which has constant power distribution in time and frequency domain. We design the signal structure to improve the performance with the repeated CAZAC sequence, and we design a receiver to optimize the proposed structure. Computer simulation results show that the proposed structure is superior to the conventional structure considering frame synchronization, frequency synchronization and channel equalization on typical wireless mobile channel environment.

• Journal of Ocean Engineering and Technology
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• v.24 no.1
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• pp.166-171
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• 2010

In this paper, the front-end of a digital receiver with a 25 kHz carrier frequency, 5 kHz symbol rate, and any excess-bandwidth is designed using two basic facts. The first is known as the uniform sampling theorem, which states that the sampled sequence might not suffer from aliasing even if its sampling rate is lower than the Nyquist sampling rate if the analog signal is a bandpass one. The other fact is that if the sampling rate is 4 times the center frequency of the sampled sequence, the front-end processing complexity can be dramatically reduced due to the half of the sampled sequence to be multiplied by zero in the demixing process. Furthermore, the designed front-end is simplified by introducing sub-filters and sub-sampling sequences. The designed front-end is composed of an A/D converter, which takes samples of a bandpass filtered signal at a 20 kHz rate; a serial-to-parallel converter, which converts a sampled bandpass sequence to 4 parallel sub-sample sequences; 4 sub-filter blocks, which act as a frequency shifter and lowpass filter for a complex sequence; 4 synchronized switches; and 2 adders. The designed front-end dramatically reduces the computational complexity by more than 50% for frequency shifting and lowpass filtering operations since a conventional front-end requires a frequency shifting and two lowpass filtering operations to get one lowpass complex sample, while the proposed front-end requires only four filtering operation to get four lowpass complex samples, which is equivalent to one filtering operation for one sample.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.40 no.11
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• pp.17-26
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• 2003

To reduce the nonlinear distortion of high power amplifier(HPA) in down link OFCDM system to employ time domain spreading, we apply technology which transmits MPSK(Multilevel-PSK) signal after clipping on multilevel input signal of IFFT subcarrier. In case that the nonlinear distortion of HPA is considered in AWGN channel, performacne of clipping OFCDM system using extended m sequence is over 2.2㏈ better than that of OFCDM system using extended m sequence when the number of user is 8 and 16. In case that the nonlinear distortion of HPA is considered in quasi-static channel, performacne of clipping OFCDM system using extended m code is over 2㏈ better than that of OFCDM system using extended m sequence when the number of user is 8 and 16.

• Parasites, Hosts and Diseases
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• v.39 no.2
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• pp.151-160
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• 2001

Randomly selected 435 clones from Acanthamoeba healyi cDNA library were sequenced and a total of 387 expressed sequence tags (ESTs) had been generated. Based on the results of BLAST search, 130 clones (34.4%) were identified as the genes enconding surface Proteins , enzymes for DNA, energy Production or other metabolism, kinases and phosphatases, protease, proteins for signal transduction, structural and cytoskeletal proteins, cell cycle related proteins, transcription factors, transcription and translational machineries, and transporter proteins. Most of the genes (88.5%) are newly identified in the genus Acanthamoeba. Although 15 clones matched the genes of Acanthamoeba located in the public databases, twelve clones were actin gene which was the most frequently expressed gene in this study. These ESTs of Acanthamoeba would give valuable information to study the organism as a model system for biological investigations such as cytoskeleton or cell movement, signal transduction, transcriptional and translational regulations. These results would also provide clues to elucidate factors for pathogenesis in human granulomatous amoebic encephalitis or keratitis by Acanthamoeba.

• ETRI Journal
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• v.19 no.1
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• pp.1-12
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• 1997

In this paper, we present an improved multicarrier direct sequence (DS) code division multiple access (CDMA) scheme by modifying the system originally proposed by Kondo and Milstein [13]. In this modified system, different spreading sequences multiplied by a data sequence modulate different carriers. This is to prevent the multiple access capability from reducing when the fading characteristics of different carrier frequencies are highly correlated. We have derived a formula which determines the mean values of the relative received signal strength in a single carrier DS CDMA rake system and in a multicarrier DS-CDMA system. We present results on the comparison of the bit error rate (BER) performance of the two systems including the effect of correlation between fading characteristics of different frequencies under various multipath fading conditions. The results indicate that with 50 users the modified multicarrier DS CDMA system can achieve an uncoded irreducible BER of $1.7{\times}10^{-3}$ with an average received signal-to-noise ratio per bit of 10dB, which is better that $3.0{\times}10^{-3}$ achieved by the single carrier DS CDMA rake system, and also show that if multicarrier CDMA system is used with respect to single carrier CDMA system, the SNR gain is up to 4.5 dB for the uncode BER of $10^{-3}$ being achieved.

• BMB Reports
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• v.40 no.6
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• pp.1095-1099
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• 2007

Endonuclease G (EndoG) is a mitochondrial non-specific nuclease that is highly conserved among the eukaryotes. Although the precise role of EndoG in mitochondria is not yet known, the enzyme is released from the mitochondria and digests nuclear DNA during apoptosis in mammalian cells. Schizosaccharomyces pombe has an EndoG homolog Pnu1p (previously named SpNuc1) that is produced as a precursor protein with a mitochondrial targeting sequence. During the sorting into mitochondria the signal sequence is cleaved to yield the functionally active endonuclease. From the analogy to EndoG, active extramitochondrial Pnu1p may trigger cell killing by degrading nuclear DNA. Here, we tested this possibility by expressing a truncated Pnu1p lacking the signal sequence in the extramitochondrial region of pnu1-deleted cells. The truncated Pnu1p was localized in the cytosol and nuclei of yeast cells. And ectopic expression of active Pnu1p led to cell death with fragmentation of nuclear DNA. This suggests that the Pnu1p is possibly involved in a certain type of yeast cell death via DNA fragmentation. Although expression of human Bak in S. pombe was lethal, Pnu1p nuclease is not necessary for hBak-induced cell death.

• BMB Reports
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• v.34 no.4
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• pp.371-378
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• 2001

The Glycoprotein D (gD) gene of the HSV-1 strain F was cloned, sequenced, recombinated into the HcNPV (Hyphantria cunea nuclear polyhedrosis virus) expression vector and expressed in insect cells. The gD gene was located in the 6.43 kb BamHI fragment of the strainF. The open reading frame (ORF) of the gD gene was 1,185 by and codes 394 amino acid residues. Recombinant baculoviruses, GD-HcNPVs, expressing the gD protein were constructed. Spodoptera frugiperda cells, infected with the recombinant virus, synthesized a matured gX-gD fusion protein with an approximate molecular weight of 54 kDa and secreted the gD proteins into the culture media by an immunoprecipitation assay The fusion gD protein was localized on the membrane of the insect cells, seen by using an immunofluorescence assay The deduced amino acid sequence presents additional characteristics compatible with the structure of a viral glycoprotein: signal peptide, putative glycosylation sites and a long C-terminal transmembrane sequence. These results indicate the utility of the HcNPV-insect cell system for producing and characterizing eukaryotic proteins.

• Phonetics and Speech Sciences
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• v.1 no.1
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• pp.63-67
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• 2009

In this paper, in order to protect music copyrights, we propose a music identification system which is scalable to the number of pieces of registered music and robust to signal-level variations of registered music. For its implementation, we define the new concepts of 'music word' and 'music phoneme' as recognition units to construct 'music acoustic models'. Then, with these concepts, we apply the HMM-based framework used in continuous speech recognition to identify the music. Each music file is transformed to a sequence of 39-dimensional vectors. This sequence of vectors is represented as ordered states with Gaussian mixtures. These ordered states are trained using Baum-Welch re-estimation method. Music files with a suspicious copyright are also transformed to a sequence of vectors. Then, the most probable music file is identified using Viterbi algorithm through the music identification network. We implemented a music identification system for 1,000 MP3 music files and tested this system with variations in terms of MP3 bit rate and music speed rate. Our proposed music identification system demonstrates robust performance to signal variations. In addition, scalability of this system is independent of the number of registered music files, since our system is based on HMM method.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.18 no.1 s.116
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• pp.90-95
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• 2007

Chaotic OOK(On-Off Keying) modulation method can be used in LDR(Low Data Rate) UWB systems. The chaotic generator in one of the most important circuit in this system. The traditional chaotic generator circuits using analog feed back technique have low yield characteristic due to the process variation. A novel quasi-chaotic signal generator using digital PN-sequence in proposed in this paper and verified in 0.18um CMOS teleology.