• Herbal Formula Science
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• v.11 no.2
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• pp.185-196
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• 2003

Depression is very common mental disorder, so many people suffer from it, which makes the treatment of depression important. Many drugs to treat depression were developed and being prescripted. But they have a lot of side effects, so it needs to develop drugs without side effects or with less side effects. Herbal medicines have been used to treat not only physical disorder but also mental disorder and it has been reported that they have less side effects. Therefore, there is the need to discover and use herbal medicine with antidepressant effect. The purpose of this study was to reseach Antidepressant effect of Licium chinense Mill. and its influence on serotonin and its metabolite of depression model rats. We used 'forced swimming test(FST)' to know antidepressant effect of Licium chinense Mill. and HPLC to check the influence on serotonin and its metabolite(5-HIAA) of Licium chinense Mill. after rats' brains were divided into cerebral cortex, striatum, hypothalamus and hippocampus. The results were obtained as follows : In the study of antidepressant effect by 'forced swimming test(FST)' method, Licium chinense Mill. had a significant antidepressant effect. In the study of influence on serotonin and 5-HIAA by HPLC, Licium chinense Mill. mainly increased serotonin and 5-HlAA of cerebral cortex and striatum signigficantly among 4 parts of rat's brain above-mentioned. These results suggest that Licium chinense Mill. has antidepressant effect that may be related with the increase of serotonin and its metabolite as its mechanism, but more precise experiments will be need to prove their relation.

• Journal of Convergence for Information Technology
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• v.10 no.3
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• pp.16-21
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• 2020

This paper describes the jamming characteristics of a stand-off jammer jamming the LPI radar. The LPI radar reduces the side lobes of the receiving antenna to reduce the effect of jamming. It is easy a radar to predict the effect of jamming on a self-protection jammer where the jammer is in the same position as the target. However, for stand-off jammer jamming at different locations from the target, the prediction of jamming effect is complex. In this paper, the jamming effect of LPI radar is analyzed using signal to jamming ratio and burn-through range. Also, when the antenna's side lobe decreases below -30 dB, the stand-off jamming effect in the side lobe direction is weak. So we proposed a new jamming method for the main lobe and analyzed the jamming effect. This study is expected to be useful for the design and operation of aircraft jammers.

• PNF and Movement
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• v.11 no.2
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• pp.127-134
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• 2013

Purpose : The purpose of this study of normal elderly and stroke patients by comparing the dominant side and recessive side was to evaluate the differents between each Methods : Thirty-two elderly participated in this study. They were classified two groups: stroke patients group and the normal elderly group. Outcome measures were: general characteristics and BMD. General characteristics included age, height, weight and body mass index. BMD was represented in the osteoporosis index, T-score and Z-score. The measurements of bone mineral density were evaluated on the calcaneus region of the dominant and recessive side, using OsteoPro. The data analyzed using SPSS 17.0 software and the Paired-sample T-test and the Independent-sample T-test Results : OI, T-score, Z-score showed no significant differences between dominant side and recessive side in normal elderly group. But stroke patients group showed OI, T-score, Z-score significant differences between paretic side and nonparetic side. Change score subtracted recessive side from dominant side was significant differences between stroke patients group and normal elderly group. Conclusion : There is positive relationship between physical activity and BMD in stroke patients. Therefore, improved physical activity can have a beneficial effect by reducing osteoporosis in stroke patients, considering a positive relationship between physical activity and BMD.

• Journal of Pharmacopuncture
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• v.4 no.3
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• pp.93-99
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• 2001

Objective : This study was performed to examine the Herbal Acupuncture decrease the side effect of Bee Venom. Methods: We treated Bee Venom and various Herbal Acupuncture mixed Bee Venom using double blind test to 70th health youth, and checked pain, edema size, CBC, Serum biochemistry and Thermography. Results: 1. Herbal Acupuncture made by Morus bombycis Koidzumi showed good results to decrease the side effect of Bee Venom than any other Herbal Acupuncture. 2. We examined CBC, ESR and Serum biochemistry before and after treated. Special change was not showed. 3. We observed the pain and edema after treated Bee Venom and Morus bombycis Koidzumi Herbal Acupuncture mixed Bee Venom. We knew that Morus bombycis Koidzumi Herbal Acupuncture was decrease the pain and edema due to Bee Venom. 4. According to these clinical studies, Morns bombycis Koidzumi Herbal Acupuncture has a possibility to be a good partner of Bee Venom.

• Journal of Pharmacopuncture
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• v.13 no.1
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• pp.87-92
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• 2010

Objectives:This study was performed to examine the side effect of inflammatory reactions of Pharmacopuncture lubricants (CF and JsD) using animal model. Methods:Pharmacopuncture lubricants (CF and JsD) were treated repeatedly the same point in Sprague-Dawley rats. And after finish the treatment, we obtain the tissue of muscle layer in rats where Pharmacopuncture lubricants were treated. And we observed the tissue how the change occurred in HE staining. Results: 1. There was no evidence to make inflammation induced by pharmacopuncture lubricants except 4 weeks treated group. 2. Only 4 weeks treated group(CF, JsD) were showed some infectional tissue's view in H-E staining. But it is not certain due to Pharmacopuncture lubricants. Conclusion:It appears that prolonged usage of pharmacopuncture lubricant on the specific point can induce inflammation, so we may be careful for treating time and point using pharmacopuncture lubricant in clinics.

• Geomechanics and Engineering
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• v.15 no.3
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• pp.911-917
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• 2018

This paper concerns a numerical investigation on the effect of construction sequence on three-arch (3-Arch) tunnel behavior. A three-arch tunnel section adopted in a railway tunnel construction site was considered in this study. A calibrated 3D finite element model was used to conduct a parametric study on a variety of construction scenarios. The results of analyses were examined in terms of tunnel and ground surface settlements, shotcrete lining stresses, loads and stresses developed in center column in relation to the tunnel construction sequence. In particular, the effect of the side tunnel construction sequence on the structural performance of the center structure was fully examined. The results indicated that the load, thus stress, in the center structure can be smaller when excavating two side tunnels from opposite direction than excavating in the same direction. Also revealed was that no face lagging distance between the two side tunnels impose less ground load to the center structure. Fundamental governing mechanism of three-arch tunnel behavior is also discussed based on the results.

• Journal of Ocean Engineering and Technology
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• v.36 no.2
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• pp.91-100
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• 2022

In general, the effect of roll motion is not considered in the study on maneuverability in calm water. However, for high-speed twin-screw ships such as the DTMB 5415, the coupling effects of roll and other motions should be considered. Therefore, in this study, the estimation of maneuverability using a 4-degree-of-freedom (DOF; surge, sway, roll, yaw) maneuvering mathematical group (MMG) model was conducted for the DTMB 5415, to improve the estimation accuracy of its maneuverability. Furthermore, a study on the change in turning performance according to the fin angle was conducted. To accurately calculate the lift and drag forces generated by the fins, it is necessary to consider the three-dimensional shape of the wing, submerged depth, and effect of interference with the hull. First, a maneuvering simulation model was developed based on the 4-DOF MMG mathematical model, and the lift force and moment generated by the side fins were considered as external force terms. By employing the CFD model, the lift and drag forces generated from the side fins during ship operation were calculated, and the results were adopted as the external force terms of the 4-DOF MMG mathematical model. A 35° turning simulation was conducted by altering the ship's speed and the angle of the side fins. Accordingly, it was confirmed that the MMG simulation model constructed with the lift force of the fins calculated through CFD can sufficiently estimate maneuverability. It was confirmed that the heel angle changes according to the fin angle during steady turning, and the turning performance changes accordingly. In addition, it was verified that the turning performance could be improved by increasing the heel angle in the outward turning direction using the side fin, and that the sway speed of the ship during turning can affect the turning performance. Hence, it is considered necessary to study the effect of the sway speed on the turning performance of a ship during turning.

• Korean Journal of Oriental Medicine
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• v.9 no.2
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• pp.107-119
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• 2003

In this study, Kami-honghwa-tang (KH-19) was designed and animal study was conducted to evaluate its efficacy on the reduction of the side effect of radiotherapy. Bone marrow toxicity is one of the major side effect of radiotherapy which cause the reduction of blood cells, and KH-19 was designed to protect and enforce blood. C57BL/6 mice were irradiated with 4 Gy of gamma ray, and divided into control group which was treated with water and KH-19 group which was treated with 1.5g/Kg of KH-19 up to 4 weeks. KH-19 group showed significantly increased white blood cells, lymphocytes and platelet count compared with control group (p<0.05). When bone marrows were examined, KH-19 group showed higher cell densities than control group (p=0.06). KH-19 may increase blood cell count after radiation by its protective effects on bone marrow.

• PNF and Movement
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• v.9 no.3
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• pp.25-29
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• 2011

Purpose : We investigated the effect of anti-flexion taping at the proximal interphalangeal joints on the gait in stroke patients with clawing toe. Methods : Nineteen patients (mean age $63.26{\pm}9.16$ years) with clawing toe were studied. Gait performance was measured under two different conditions : (1) non-tape (2) application of tape. Gait velocity, step time and stride length were examined with the GAITRite system Results : Compared to the non-tape control condition, step time of the hemiparetic side increased significantly after the application of tape(p=0.03). There was no significant mean differences between the taped and control conditions for stride length of the hemiparetic side and velocity. Conclusion : Whilst the anti-flexion tape at the proximal interphalangeal joints changed the walking by providing significant step time effect, positive changes were noted in stride length of the hemiparetic side after tape application. These findings indicate that anti-flexion tape procedures do not significantly alter stride length of the hemiparetic side and velocity.

• Journal of Korea Trade
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• v.26 no.6
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• pp.96-117
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• 2022

Purpose - Considering the recent instability of world economy and its heavy dependence on foreign, Korea must formulate breakthrough approaches to proactively cope with these adverse global developments. As such, this study aims to ascertain how participation in global value chains (GVCs) relates to corporate productivity and derive policy implications. Design/methodology - This study utilizes the microdata of Korean manufacturers to develop indicators of GVC participation at the enterprise level and analyzes the effects of GVC participation on the firm's total factor productivity by using fixed effect model. Findings - Enterprises with highest rates of export-side GVC participation see their productivity grow as their export-side GVC participation rates increase. In addition, when companies are classified by their export-side GVC participation rates, increasing export values improves all firm's productivity. In particular, those with low participation rates are analyzed to achieve higher productivity by increasing their imports, not only exports, which implies that companies with lower export-side GVC participation can boost productivity by reinforcing their export and import activities. Originality/value - This research paper distinguishes itself from others in that it makes a novel attempt to design the indicators of GVC participation at the enterprise level, not at the national or industry level. In addition, this study contributes to the existing literature by dividing companies into subgroups depending on their GVC participation rates for each of export and import and identifying variances in the effect of GVC participation on productivity growth among subgroups.