• Transactions of the Korean Society of Machine Tool Engineers
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• v.15 no.6
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• pp.114-120
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• 2006

Front-end side members of vehicles are structures with the greatest energy absorbing capability in a front-end collision of vehicles. This paper was undertaken to analyze the energy absorption characteristics of spot welded hat and double hat-shaped section members under the axial collapse. The experiments were performed with respect to the various collapse velocities. It was expected that para-closed sections would show collapse characteristics which be quite different from those of perfectly closed sections. The collapse velocities were selected as follows: the velocities in the hat-shaped section members were 0.00017m/sec, 0.017m/sec, 4.7m/sec, 6.5m/sec, 6.8m/sec, 7.2m/sec, and 7.3m/sec those in the double hat-shaped section members were 0.00017m/sec, 0.017m/sec, 6.5m/sec, 6.8m/sec, 7.2m/sec 7.3m/sec, and 7.9m/sec. In the program system presented in this study, an explicit finite element code, LS-DYNA3D, is adopted for simulating complicated collapse behavior of the hat and double hat-shaped section members under the same condition of the collapse test. The validity of simulation was confirmed by the comparison between the simulation result and the collapse experiment.

• Korean Journal of Adult Nursing
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• v.12 no.4
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• pp.497-506
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• 2000

The purpose of this phenomenological study was to explore and describe the experience of people with HIV/AIDS. Three men and three women with HIV/AIDS participated in the study. They were asked open-ended and descriptive questions in order for them to talk about their experience in their own terms. Interviews were audiotaped and transcribed to maintain data integrity and to reduce perceptual bias. The transcripts were analyzed by the Colaizzi method. Member checks from the participants were used to validate the emergent themes. Seven themes emerged from the analysis. 1. People with HIV/AIDS have a strong impact and emotional reaction when receiving positive HIV test results. 2. All people with HIV/AIDS attempt to conceal HIV infection because of fear of stigma or rejection. 3. After the initial brief traumatic reaction to HIV/AIDS diagnosis, all participants feel lonely because they had no one to express or share their own experiences. 4. People with HIV/AIDS reflect on their life, think about the death and dying process and they become depressed. 5. Most participants feel that the family members who know his/her diagnosis are a big source of support. 6. According to the normativeness of infection route of HIV, the degree of guilty feeling differs among participants. 7. Although all participants think medication is a lifeline, the adherence to medication is not maintained because of side effects, denial and concealment of HIV/AIDS. The results of this study may help nurses and other health care workers to implement more efficient nursing strategies for people with HIV/AIDS by more deeply understanding their experience.

• Journal of the Korean Society for information Management
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• v.18 no.2
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• pp.165-186
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• 2001

The purpose of this study is to explore practical methods of interlibrary loan system, linked with information retrieval system. The process and current status of interlibrary loan was investigated and analyzed at medical libraries in this study. In order to find the way of utilizing data from information retrieval and document request at the same time, the author tries to develop a way of linking PubMed, Union Catalog and ILL system. This study shows that hit record of information retrieval was saved in type of MEDLINE, XMLJSGML and reused for document delivery services. It seems to be efficient that the maintenance of Union Catalog was managed by all of member libraries, and data were retrieved at server and client side at once. In addition, it was found that user information can be checked by the IP and ILL system can be used for requested document by the saved result.

• Korean Journal of Veterinary Research
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• v.44 no.2
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• pp.195-200
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• 2004

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family and potent inducer of apoptosis. TRAIL has been shown to effectively limit tumor growth in vivo without detectable cytotoxic side effects. Interferon (IFN)-${\gamma}$ often modulates the anti-cancer activities of TNF family members including TRAIL. We previously reported that IFN-${\gamma}$ enhanced TRAIL-induced Apoptosis in HeLa cells without the unknown mechanism. In this study, we investigated whether IRF-1 involves in IFN-${\gamma}$-enhanced TRAIL-induced apoptosis. We exposed HeLa cells to IFN-${\gamma}$ for 12 hours and then treated with recombinant TRAIL protein. No apoptosis was induced in cells pretreated with IFN-${\gamma}$, and TRAIL only induced 30% apoptosis after 3 hours treatment. In HeLa cells pretreated with IFN-${\gamma}$, TRAIL induced cell death to more than 75% at 3 hours, showed that IFN-${\gamma}$-pretreatment enhanced HeLa cell death to TRAIL-induced apoptosis. To investigate the functional role of IRF-1 in IFN-${\gamma}$-enhanced TRAIL-induced apoptosis, IRF-1 was overexpressed by using an adenoviral vector AdIRF-1. IRF-1 overexpression increased apoptotic cell death and significantly enhanced apoptotic cell death induced by TRAIL when infected cells were treated with TRAIL. Our findings show that IFN-${\gamma}$ enhances TRAIL-induced apoptosis by IRF-1 in HeLa cells.

• Microbiology and Biotechnology Letters
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• v.33 no.2
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• pp.90-95
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• 2005

An Actinomycetes producing an anti-VRSA (vancomycin-resistant Staphylococcus aureus) substance was isolated from soil. The cultural, morphological, physiological and phylogenetic analyses of an isolated strain were investigated for identification. Cultural characteristics based on ISP (International Streptomyces Project) were as follows: white aerial mycelium, yellow reverse side, and good growth on various medium. Also, the isolate did not produce the soluble pigment. Morphological characteristics were showed cylindrical spore chain and smooth spore surface by SEM (Scanning Electron Microscope). Physiological characteristics were showed LL-type by DAP isomer analysis and detected glycine, glutamic acid and alanine. A phylogenetic analysis of the 16S rDNA provided a clue that the isolated strain was actually a member of the genus Streptomyces, because the determined sequence exhibited a higher homology with Streptomyces echinatus. The isolate was identified to be a genus of Streptomyces sp.. The optimal culture conditions for the maximum production of anti-VRSA substance by Streptomyces sp. were attained in a culture medium composed of $2.0\%$ (w/v) glucose, and $0.4\%$ (w/v) yeast extract. The anti-VRSA substance was highly produced after 5 days of culture. Optimal pH and temperature conditions for the production of anti-VRSA substance were pH 7.0 and $28^{\circ}C$, respectively.

• Computational Structural Engineering
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• v.9 no.2
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• pp.121-131
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• 1996

This work proposes an optimality criteria applicable to the optimum design of plane frames subject to multiple behavioral constraints on member stresses and lateral displacements of nodes and also to side constraints on design variables. The method makes use of a first order approximation for both deflection and stress constraints instead of the zero order approximation based on the concept of FSD (fully stressed design). A redesign algorithm is derived from a mathematically rigorous method which uses the Newton-Raphson method to solve the system of nonlinear constraint equations and reduces the design space whenever minimum size restrictions become active. When applied to worked examples it proved more accurate and efficient, and it is often found that optimum designs are not fully stressed designs. This fact suggests that this rigorous method is worth what it claims for complicated computing and thus had better replace the crude stress ratio algorithm adopted by the majority of optimality criteria approaches. This is particularly true as long as we enjoy ever-increasing computing power at negligible costs.

• Journal of the Korean Society of Safety
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• v.20 no.4 s.72
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• pp.54-62
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• 2005

This Study is to find out how RC beam mixed with sawdust acts comparing with normal beam without sawdust mixture, and how they can be applied to the actual structural frame, despite a Int that they are mixed with waste material : saying sawdust. ED3H1, ED3H2, ED5H1, ED5H2, ED3H1UB, ED5H1UB, ED3H2L, ED5H2L and Normal without sawdust mixture are main factor to be tested here in order to apply them to the actual case. D and H means diameter 3cm or 5cm, and holes one and two respectively. And all variables are tested with each two for one variables. Test results are compared using crack diagrams and strain & loads. There are eleven(11)% capacity decrease between ED 3H1 and ED5H1 in rebar, strain. Left and right side crack shapes are much similar in variable ED3H2L having maximum capacity 14.5 tone. ED5H2L having maximum capacity thirteen(13)tone, in case of normal 19.6 tone. Two holes in beam rather on the longitudinal direction than on the forcing direction can be more effective to keep the original capacity of the beam because this case can distribute load more uniformly. There is 33% capacity decreased in case of diameter five(5)cm, compared to diameter three(3)cm. Two holes give thirty nine(39) percent capacity decrease than one of diameter three(3)cm.

• Journal of Korean Society of Steel Construction
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• v.18 no.2
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• pp.261-270
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• 2006

In this paper, the basic data regarding the application of the MSC (Modular Steel Concrete) beam are presented by comparing the experimental value with the theoretical value, focusing on the bending behavior of the Lip-type MSC beam, which is composed of steel and concrete. Considerable manpower is needed to fabricate the traditional MSC beam, particularly for the tasks of cutting, welding, etc. Because much time is needed to fabricate the traditional SC beam, the prefabrication concept is introduced, easily produce the required size of the SC beam by prefabricating the side module and the lower module, which is made up of a steel sheet. The result indicates that the method of uniting the modules, an d the composition method with concrete, should be improved. The proposed MSC beam can be used as a new structural member by increasing its coherent reinforcement with modules and the composition ratio of steel and concrete through a future study.

• Journal of muscle and joint health
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• v.3 no.1
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• pp.4-22
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• 1996

Purposes of this study were to identify a hospital-based home care model and to improve the physical, emotional and economical effectiveness of arthritic patients through medical and nursing team approach. The design in nonequivalent control group pretest-posttest design with matched samples in terms of age, sex and disease severity. Fifty two patients in each group were assigned in Seoul, Kyunggi, Kangwon and Kwangju. Before and after 6-month period of home care, level of pain, duration of morning stiffness, Richie Index, ADL, self efficacy, depression, cost expenditure were measured. Nine patients were excluded from the control group in the period of study because of denial of participation. Contents of home care provided to the experimental group include mainly distribution of prescribed drugs, 'assessment of patients' condition and side-reactions of drug. All of the information related to the home care patient were reported to the physician. On the bases of these data, the physician prescribe the specific drugs to each patient. Each patient visited the physician every 2 or 3 month for laboratory test. Patients assigned to the control group visited the outpatient clinic once a month as usual. Null hypotheses were selected because physicians concerned about the ineffective change of patients' conditions due to indirect communication with patients through nurses. Level of pain, Richie index, ADL, self-efficacy, depression, duration of morning stiffness and direct medical cost were the home care provided to them. If a family member accompany in a home care group can save 10,676 Won/month in Seoul, 34,000 Won/month in other districts. Other in-direct cost for transportation and meal can also be saved. In conclusion, those patients with low level of ADL, high level of pain and Richie index, living in the remote area definitely need the home care.

• Journal of Pharmacopuncture
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• v.22 no.1
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• pp.16-27
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• 2019

Generative and vegetative parts of the cactuses have had a long-lasting position in folk medicine and their effects could partly be confirmed in scientific experiments. Nowadays, the cactus, fruits, and cladodes are the focus of many studies because of their desirable properties. Therefore, the summarized reports of valuable properties of medicinal plants may be a good way to familiarize researches with a new source of drugs with lower side effects and higher efficacy. Opuntia dillenii, a well-known member of the Cactaceae family, is used as a medicinal plant in various countries and grows in the desert, semi-desert, tropical and sub-tropical areas. It shows diverse pharmacological activities such as: antioxidant, anti-inflammatory, anti-tumor, neuroprotective, hepatoprotective, hypotensive etc. OD fruit also possesses valuable constitutes for instance: betalains, ascorbic acid, total phenol, protein as well as essential elements which suggest the significant potential of this plant as a complementary therapy against several pathological conditions. This review describes experimental evidence about pharmacological and therapeutic potential of OD in order to give the basis of its application in the prevention and treatment of some chronic diseases. More studies on OD can help better understanding of its pharmacological mechanism of action to explain its traditional uses and to identify its potential new therapeutic applications.