• Animal cells and systems
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• v.14 no.4
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• pp.267-274
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• 2010

The decrease in sperm quality under heat stress causes a great loss in animal husbandry production. In order to reveal the mechanism underlying the sperm quality decrease caused by heat stress, we first established a mild heat-treated mouse model. Then, the sperm quality was identified. Further, the testicular proteome profile was mapped and compared with the control using 2D electrophoresis and mass spectrometry. Finally, the differential expressed proteins involved in the heat stress response were identified by real-time PCR and Western blotting. The results showed that heat stress caused a significant reduction in mouse sperm quality (P<0.05). Further, 52 protein spots on the 2D gel were found to differ between the heat-shocked tissues and the control. Of these spots, some repair proteins which might provide some explanation for the influence on sperm quality were found. We then focused on Bag-1, Hsp40, Hsp60 and Hsp70, which were found to be differently expressed after heat shock (P<0.05). Further analysis in this heat-shocked model suggests numerous potential mechanisms for heat shock-induced spermatogenic disorders.

• Publications of The Korean Astronomical Society
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• v.12 no.1
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• pp.111-143
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• 1997

We have developed a spherical FCT code in order to simulate the interaction of supernova remnants with stellar wind bubbles. We assume that the density profile of the supernova ejecta follows the Chevalier mode1(1982) where the outer portion has a power-law density distribution($\rho{\propto}\gamma^{-n}$) and the SN ejecta has a kinetic energy of $10^{51}$ ergs. The structure of wind bubble has been calculated with the stellar mass loss rate $\dot{M}=5\times10^{-6}M_{\odot}/yr$ and the wind velocity $\upsilon=2\times10^3$ km/s We have simulated seven models with different initial conditions In the first two models we computed the evolution of SNRs with n=7 and n=14 in the uniform medium The numerical results agree with the Chevalier's similarity solution at early times. When all of the power-law portion of the ejecta is swept up by the reverse shock, the evolution slowly converges to the Sedov-Taylor stage. There is not much difference between the two cases with different n's The other five models simulate SNRs produced inside wind bubbles. In model III, we consider the SN ejecta of 1.4 $M_{\odot}$ and the radius of bubble ~2.76 pc so that ratio of the mass $\alpha(=M_{W.S}/M_{ej}$ is 2. We follow the complex hydrodynamic flows produced by the interaction of SN shocks with stellar shocks and with the contact discontinuities, In the model III, the time scale for the SN shock to cross the wind shell $\tau_{cross}$ is similar to the time scale for the reverse shock to sweep the power-law density profile $\tau_{bend}$. Hence the SN shock crosses the wind shell. At late times SN shock produces another shell in the ambient medium so that we have a SNR with double shell structure. From the numerical results of the remaining models, we have found that when $\tau_{cross}/\tau_{bend}\leq2$, or equivalently when $\alpha\leq50$, the SNRs produced inside wind bubbles have double shell structure. Otherwise, either the SN shock does not cross the wind shell or even if it crosses at one time, the reverse shock reflected at the center accelerates the wind shell to merge into the SN shock Our results confirm the conclusion of Tenorio-Tagle et a1(1990).

• Proceedings of the Korean Nuclear Society Conference
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• 1998.05a
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• pp.635-640
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• 1998

Thermal fluid mixing behavior during a postulated medium-size hot leg break loss of coolant accident is analyzed for the international comparative assessment study on pressurized thermal shock (PTS-ICAS) proposed by OECD-NEA. The applicability of RELAP5 code to analyze thermal fluid mixing behavior is evaluated through a simple modeling relevant to the problem constraints. Based on the calculation result, the onset of Thermal stratification is investigated using Theofanous's empirical correlation. Sensitivity calculations using a fine node model and crossflow model are also performed to evaluate the modeling capability on multi-dimensional characteristics related to thermal fluid mixing.

• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.5
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• pp.176-180
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• 2013

After-treatment apparatus ceramic DPF (diesel particulate filter) have been applied to reduce harmful particulate matters(PM) among emissions from diesel engines so far, but they are easy to be fragile and weak in thermal shock. This research aims to investigate a metal type filter which is superior in mechanical strength and heat conduction rate and is beneficial economically in manufacturing. Basic performance of metal DPF such asloading test, temperature gradient test, thermal shock test, heat resistant test and back pressure was carried out. And then their experimental data provided key informations in designing and manufacturing such as detailed structures of metal mesh filter. Also diesel engine and vehicle of 2957cc displacement was tested under lug-down 3 mode and CVS-75 mode. PM reduction efficiency was 54.5% using metal DPF without loss of performance and fuel consumption.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2011.11a
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• pp.881-884
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• 2011

Secondary throat supersonic exhaust diffusers were designed by Normal-shock theory and manufactured. Experimental studies of the diffusers were performed using nitrogen gas of room temperature. It showed a difference about 18% between the experimental and theoretical results. The difference was shown by friction loss at the wall of the diffuers.

• 한국연소학회:학술대회논문집
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• 2012.11a
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• pp.301-302
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• 2012

During a last decade, detonative combustion is promising combustion mechanism of high-speed propulsion systems, but is more rigorously considered in these days as a game-changer for the improvement of thermodynamic efficiency of propulsion and power generation systems. Regardless of the skepticism about the pressure loss associated with the strong shock waves, it is shown that the additional compression by the strong shock wave exhibits increased thermodynamics efficiency that is not achievable by conventional compression systems. Present talk will give an introduction to the concepts and the recent activities on the pressure gain combustors (PGC) researches based on detonation phenomena.

• Journal of Family Relations
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• v.22 no.3
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• pp.73-101
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• 2017

Objectives: This study is to understand the experiences of overcoming pain of loss of family survivors in Suicide Bereavement Support Group(SBSG). Method: Experiential data was collected by in-depth interview(FGI, individual) to 10 family survivors(over 19) who having an experience participating in SBSG over 5months and analyzed using qualitative methodology. Results: We drew the result that 'SPACE model' which structuralize by 5 stages of suicide survivors' experience of SBSG of time path. SPACE model configured as follow: Stage1, Space in vacuum, the time to feel a sense of overwhelming feeling like pain, fear, alienation after loss of suicide, Stage2, Probing, when to find informations and resources to help survivors themselves, Stage3, Acclimation, having experiences empathy and healing as in SBSG, Stage4, Composure, accepting SBSG meaning as a part of their lives, loss of my family by suicide, and the beginning of bereavement, Stage5, Endurance, overcoming suffering through SBSG and try to help other survivors. Conclusions: SBSG is the opportunity for family survivors to overcome the pains from loss of suicide, shock, anger, grief, etc., and to empower them to help other suicide survivors.

• New & Renewable Energy
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• v.20 no.2
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• pp.35-43
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• 2024

A pump turbine is a technically matured option for energy production and storage systems. At the off-design operating range, the pump turbine succumbed to flow instabilities, which correlated with the pump turbine geometry. A low specific speed pump turbine was designed and modified according to the impeller blade angle. Reynolds-Average Navier-Stokes is carried out with a shear stress transport turbulence model to evaluate the detailed flow characteristics in the pump turbine. The impeller blade inlet angle (𝛽₁) and outlet angle (𝛽₂) are used to evaluate hydraulic loss in the pump turbine. When 𝛽₁ changed from low to high value, the maximum efficiency is increased by 4.75% in turbine mode. The S-Curve inclination is reduced by 8% and 42% for changes in 𝛽₁ and 𝛽₂ from low to high values, respectively. At α = 21°, the shock loss coefficient (𝜁_s) is reduced by 16% and 19% with increases of 𝛽₁ and 𝛽₂ from low to high values, respectively. When 𝛽₁ and 𝛽₂ values increased from low to high, the impeller friction coefficient (𝜁_f) increased and decreased by 20% and 8%, respectively. Hence, the high 𝛽₂ effectively reduced the loss coefficient and S-Curve inclination.

• Journal of Microbiology and Biotechnology
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• v.25 no.12
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• pp.2125-2134
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• 2015

IrrE is a highly conserved global regulator in the Deinococcus genus and contributes to survival from high doses of UV radiation, ionizing radiation, and desiccation. Drad-IrrE and Dgob-IrrE from Deinococcus radiodurans and Deinococcus gobiensis I-0 each share 66% sequence identity. However, Dgob-IrrE showed a stronger protection phenotype against UV radiation than Drad-IrrE in the D. radiodurans irrE-deletion mutant (ΔirrE), which may be due to amino acid residues differences around the DNA-binding HTH domain. Site-directed mutagenesis was used to generate a Drad-IrrE A184S single mutant, which has been characterized and compared with the ΔirrE mutant complemented strain with Drad-irrE, designated ΔirrE-E. The effects of the A184S mutation following UV radiation and mitomycin C (MMC) shock were determined. The A184S mutant displayed significantly increased resistance to UV radiation and MMC shock. The corresponding A184 site in Dgob-IrrE was inversely mutated, generating the S131A mutant, which exhibited a loss of resistance against UV radiation, MMC shock, and desiccation. qPCR analysis revealed that critical genes in the DNA repair system, such as recA, pprA, uvrA, and ddrB, were remarkably induced after UV radiation and MMC shock in the ΔirrE-IE and A184S mutants. These data suggested that A184S improves the ability against UV radiation and MMC shock, providing new insights into the modification of IrrE. We speculated that the serine residue may determine the efficiency of DNA binding, leading to the increased expression of IrrE-dependent genes important for protection against DNA damage.

• International Journal of Highway Engineering
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• v.15 no.2
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• pp.65-71
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• 2013

PURPOSES : The objective of this study is to evaluate the effect of physical characteristics of emulsion asphalt and aggregate on performance of chip seal pavements. METHODS : In order to evaluate the performance of chip seal materials, the sweep tests and Vialit Plate Shock tests were conducted on the mixtures with five emulsion asphalt binders and three aggregate types. The sweep tests was intended to investigate the change of bonding properties between emulsion asphalt and aggregate with curing time. The Vialit Plate Shock test was used to evaluate the bonding properties of chip seal materials at low temperatures. RESULTS : Results from sweep tests showed that polymer modified emulsion asphalt can reduce the curing time by 1.5 hour comparing with typical emulsion asphalt. It is also found that the Flakiness Index of aggregates and absorption rate of binder are the major factors affecting the bonding properties of chip seal materials. The Vialit Plate Shock test results showed that the average aggregate loss of CRS-2 is ten times higher than CRS-2P No.2 indicating that the use of polymer additives in emulsion asphalt can improve the performance of chip seal materials in low temperature region. CONCLUSIONS : The use of polymer in emulsion asphalt can decrease the curing time of chip seal materials and increase the bonding properties between aggregates and asphalt binder. It is also concluded that the lower Flakiness Index and absorption rate of aggregates can improve the performance of chip seal pavement.