• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.16 no.11 s.116
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• pp.1132-1139
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• 2006

Non-contact underwater explosions against surface ship could cause extensive equipment damage during wartime service. Thus, the need to develop methods for the design of shock resistant equipment structures and systems was strongly established. In analytical methods, DDAM(Dynamic Design and Analysis Method) and transient repsonse method are used for ship shock design. In this paper, to analyze the characteristics of DDAM, medium weight shock test, DDAM and transient response analysis for missile system equipment are performed.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.11 no.1
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• pp.17-24
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• 2005

During handling unitized products, they are subjected to a variety environmental hazards. Shock and vibration hazards are generally considered the most damaging of the environmental hazards on a product, and it may encounter while passing through the distribution environment. A major cause of shock damage to products is drops during manual handling. The increasing use of unitization on pallets has been resulted in a reduction in the manual handling of products and with it a reduction in the shock hazards. This has caused and increasing interest in research focused on vibration caused damage. the use of pallets as a base for unitizing loads, aids in the mechanical handling, transportation and storage of products. Besides aiding in the handling, transportation and storage of products, a pallet also acts on and interface between the packaged goods and the distribution environment. The determination of the impact deformation of the cushioning materials such as tray cup (polymeric foam) and corrugated fiberboard pad must be carried out to design the proper packaging system providing adequate protection for the fruit, and to understand the complex interaction between the components of fruit when they relate to expected transportation vibration inputs. In this study, the theoretical analysis of impact deformation for cushioning materials by dynamic vibration. The impact deformations of SW and DW corrugated fiberboard pad in acceleration amplitudes of 0.25 G-rms and 0.5 G-rms that were usually generated in transport vehicles during distribution environments were very small compare with the thickness of corrugated fiberboard pad. The maximum of vibration acceleration level of tray cup by vibration impact was about 3.2 G-rms. The theoretical allowable acceleration (G-factor) of the pear was 0.7102 G-rms, and the maximum dynamic deformation estimated within G-factor was about 1 mm.

• YAKHAK HOEJI
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• v.51 no.1
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• pp.44-50
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• 2007

Acute septic shock is one of inflammatory diseases mediated by pro-inflammatory cytokines such as tumor necrosis factor (TNF)-${\alpha}$. In this study, we examined the pathological difference and mechanism of lipopolysaccharides isolated from E. coli (E-LPS) or S. abortus (S-LPS) on inducing acute septic shock in ICR mouse. All mice were died by intraperitoneal treatment of S-LPS with 0.75 mg/kg, whereas E-LPS treated with even 3 mg/kg only showed 30% of mice lethal, indicating that S-LPS may be more feasible in triggering a strong septic shock condition. The secretion pattern of TNF-${\alpha}$, a critical pro-inflammatory cytokine in septic shock condition, was also distinct between E-LPS- and S-LPS-treated groups. Thus, S-LPS strikingly increased serum level of TNF-${\alpha}$ (6 ng/ml) at 1 h, while E-LPS just displayed at 2 ng/ml level. However the interaction of S-LPS with LPS receptor toll like receptor (TLR)-4, was not stronger than that of E-LPS, according to experiments with macrophage cell line RAW264.7 cells. Thus, E-LPS rather than S-LPS strongly enhanced the production of TNF-${\alpha}$. Interestingly, S-LPS more strongly up-regulated splenocyte proliferation, compared to E-LPS group, whereas there was no difference between S- or E-LPS treated groups in proliferation of Balb/c- or C57BL/6-originated splenic lymphocytes. Therefore, our data suggest that S-LPS is a more active endotoxin and that the strong septic shock-inducing effect of S-LPS seems due to the enhancement of early TNF-${\alpha}$ production and S-LPS-sensitive lymphocyte proliferation.

• Journal of Energy Engineering
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• v.21 no.1
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• pp.26-32
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• 2012

This study has been performed Thermal Shock test for analyze the cause of Power drop in PV(Photovoltaic) Module. Thermal Shock test condition was performed with temperature range from $-40^{\circ}C{\sim}85^{\circ}C$. One cycle time is 30min. which are consist of low and high temperature 15min. each other. The test was performed with total 500cycles. EL, I-V were conducted every 100cycle up to 500cycles. Mono Cell resulted in 8% Power drop rates in Bare Cell and 9% in Solar Cell. In the case of Multi Cell resulted in 6% Power drop rates in Bare Cell and 13% in Solar Cell. After Thermal Shock test, Solar Cell's Power drop resulted from surface damages, but in the case of Bare Cell's Power drop had no surface damages. Therefore, Bare Cell's Power drop was confirmed as according to leakage current increase by analysis of Fill Factor after Thermal Shock test. Also, Solar Cell's Power drop rates are higher than that of Bare Cell because of surface damages and consuming electric power increase. From now on, it should be considered that analyzed the reasons of Fill Factor decrease and irregular Power drop in PV module and Cell level using cross section, various conditions and test methods.

• Structural Engineering and Mechanics
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• v.37 no.3
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• pp.257-265
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• 2011

Plant-specific analyses of 5 types of domestic reactors in Korea are performed to assure the structural integrity of the reactor pressure vessel (RPV) during transients which are expected to initiate pressurized thermal shock (PTS) events. The failure probability of the RPV due to PTS is obtained by performing probabilistic fracture mechanics analysis. The through-wall cracking frequency is calculated and compared to the acceptance criterion. Considering the fluence at the end of life expected by surveillance test, the sufficient safety margin is expected for the structural integrity of all reactor pressure vessels except for the oldest one during the pressurized thermal shock events. If the flaw with aspect ratio of 1/12 is considered to eliminate the conservatism, the acceptance criteria is not exceeded for all plants until the fluence level of $8{\times}10^{19}\;n/cm^2$, generating sufficient margin beyond the design life.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.4
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• pp.457-465
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• 2018

The expression of BCL-2 interacting cell death suppressor (BIS), an anti-stress or anti-apoptotic protein, has been shown to be regulated at the transcriptional level by heat shock factor 1 (HSF1) upon various stresses. Recently, HSF1 was also shown to bind to BIS, but the significance of these protein-protein interactions on HSF1 activity has not been fully defined. In the present study, we observed that complete depletion of BIS using a CRISPR/Cas9 system in A549 non-small cell lung cancer did not affect the induction of heat shock protein (HSP) 70 and HSP27 mRNAs under various stress conditions such as heat shock, proteotoxic stress, and oxidative stress. The lack of a functional association of BIS with HSF1 activity was also demonstrated by transient downregulation of BIS by siRNA in A549 and U87 glioblastoma cells. Endogenous BIS mRNA levels were significantly suppressed in BIS knockout (KO) A549 cells compared to BIS wild type (WT) A549 cells at the constitutive and inducible levels. The promoter activities of BIS and HSP70 as well as the degradation rate of BIS mRNA were not influenced by depletion of BIS. In addition, the expression levels of the mutant BIS construct, in which 14 bp were deleted as in BIS-KO A549 cells, were not different from those of the WT BIS construct, indicating that mRNA stability was not the mechanism for autoregulation of BIS. Our results suggested that BIS was not required for HSF1 activity, but was required for its own expression, which involved an HSF1-independent pathway.

• Journal of Distribution Science
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• v.22 no.3
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• pp.105-112
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• 2024

Purpose: This study analyzed the relationship between corporate capacity and management performance in the Korean distribution industry during the COVID-19 pandemic. Research design, data and methodology: The data for this study used the 2021 KOTRA GCL Test Data, and multiple regression analysis was performed using SPSS 26. As corporate competency, human capital and related capital of intellectual capital theory were utilized, and the global network level of social network theory was also utilized. As an additional analysis, corporate characteristics factors were used. Results: First, the level of global mindset of human capital acted as a positive factor in management performance, and the level of professional manpower did not achieve significant results. Second, related capital acted as a positive factor in corporate performance. Third, from the perspective of social network theory, the global network level of companies acted as a positive factor in management performance. Finally, the relationship between corporate characteristics and management performance was marginally significant. Conclusions: In order to improve the business performance of a company in a market shock such as the COVID-19 pandemic, it is required to strengthen the level of network construction with customers and increase the level of intellectual capital that a company has.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.2
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• pp.157-167
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• 2022

In this study, we investigated the effects of heptapeptide on cellular activation and inhibition of cellular damage induced by photoaging condition in NIH3T3 fibroblasts. Cell proliferation and extracellular matrix (ECM) expression were induced by heptapeptide. The reduced cell viability under photoaging condition through ultraviolet A (UVA) irradiation was increased by heptapeptide. And UVA-induced apoptosis, matrix metalloproteinases-1 (MMP-1) expression, and reactive oxygen species (ROS) level were decreased by heptapeptide. In addition, the inhibition of transforming growth factor-β (TGF-β)/smad signaling under UVA irradiation which resulting in reduction of ECM expression was also recovered by heptapeptide. We also tested the effect of heptapeptide under another photoaging condition through heat shock, and pre-treatment of heptapeptide prevented the phosphorylation of mitogen-activated protein kinase (MAPK) and MMP-1 expression induced by heat shock. From these results, it has been shown that the heptapeptide has protective effects on fibroblasts through the up-regulation of cellular activity and through the decreasing of intracellular ROS level induced by UVA irradiation or heat shock. It is expected that the dermal protection effect of heptapeptide can be applied as a new cosmetic material in the future.

• Korean Journal of Culture and Social Issue
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• v.21 no.1
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• pp.45-66
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• 2015

This study explored the moderating effects of social supports (family support, home friends support, foreign friends support) and cultural identity (home identity, foreign identity) on the relationships of reverse culture shock and subjective well-being. Participants were 157 returnees who left home-country prior to the age of 19 and resided in the foreign-country for more than three years. The results of hierarchical regression analyses on two-way interaction effect between reverse culture shock and each hypothesized moderator (e.g., family support, home friends support, foreign friends support, home identity, foreign identity) indicated that reverse cultural shock and subjective well-being was negatively related and their relationship was moderated only by family support. Specifically, the relationship between reverse culture shock and subjective well-being was weaker when the level of family support was higher. Subsequently, three-way interaction among reverse culture shock, one of the social support factors, and one of the cultural identity factors was investigated using hierarchical regression analyses. The results showed that the three-way interaction among reverse culture shock, family support, and home identity was significant. The slope difference tests yielded that the relationship between reverse culture shock and subjective well-being was stronger when both levels of family support and home identity were lower compared to when either level of family support or home identity was higher. These results imply that environmental factors such as family support and intrapsychic factor such as home identity might function as a buffer against the negative consequences of reverse culture shock experience.

• Microbiology and Biotechnology Letters
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• v.35 no.3
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• pp.177-183
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• 2007

Using complementation of RpoH deficient E. coli strain A7448, the rpoH gene encoding heat shock sigma factor 32 (${\sigma}^{32}$) from Methylovorus sp. strain SS1 DSM11726 was cloned and sequenced. Sequence analysis of a stretch of 1,796-bp revealed existence of an open reading frame encoding a polypeptide of 284 amino acid (32,006 dalton). Deduced amino acid sequence of the Methylovorus sp. strain SS1 RpoH showed that 59.6%, 39.1% and 51.4% identities with those of Nitrosomonas europaea (${\beta}$-proteobacteria), Agrobacterium tumefaciens ($\alpha$-proteobacteria) and E. coli (${\gamma}$-proteobacteria). The expression level of the functional ortholog of RpoH of Methylovorus sp. strain SS1 was increased transiently after heat induction, further indicating that it functions as a heat shock sigma factor.