• 전기의세계
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• 제29권1호
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• pp.21-27
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• 1980

The effect of electric shock on human body is enormousness, which leads to warmth, tingling, and even death. The mean values of perception currents obtained on 91 men and 39 women are about 0.77(mA) for men and 0.57(mA) for women. The mean value for women is approximately seven tenths that of men. An individual can tolerate, with no adverse effects, repeated exposure to the reactions associated with currents of his let-go level, and the mean value of let-go currents obtained from 27 normal men is 6.29(mA). Lethal currents flowing human body is very dangerous even for a short time. So, it is necessary to have recourse to animal experiments ot determine lethal current for human. An analysis of experimental data indicates that body weight and shock duration are important factors in determining the lethal current. It is suggested that the relationship between current and shock duration is given by I=K/.root.T, and lethal current is proportional to body weight, where I is the current in milliampere, and T is the time in seconds.

• 소음진동
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• 제10권2호
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• pp.247-253
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• 2000

The evaluation of the ride quality had been performed by the subjective method before ISO2631(International Organization for Stadard 2631) and BS6841(British Standard 6841) was precented, but many research programs have been performed by the objective method after that. On this study, the ride quality was evaluated related with the objective method which considered the vibration which the human body feels on the driver's seat while driving on the road. In particular, we made the shock absorber nonlinear model and also selected the suitable shock absorber in the part of the vibration which the human body feels into the simulation. The shock absorber of suspension was dealt with 3 cases respectively with the front wheel and rear wheel. The vibration of the car driving on the road can be transferred to the wheel, the suspension, the vehicle body, the seat and the human body. The signal which was gained from the seat(hip) and the floor(foot) of the human body was changed to the vibration signal which the human body felt through using the frequency weighting function. And then the performance of the shock absorber was calculated through the statistic processing.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2001년도 추계학술대회논문집 II
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• pp.691-694
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• 2001

The recent national contract (Ecotechnopia 21) supported by the ministry of environment puts much significance on new issues for the assessment of human effects arising from vibration and noise exposed to human. This paper focuses only on hand-arm vibration since it has been a major problem in protecting vibration exposure to human. To set up a systematic way of assessing adverse effects of hand-arm vibration, surveys were made on recent international standards and researches related to hand-arm vibration. The measurement and evaluation methods of hand-arm transmitted vibration, the relationship between vibration exposure and effects on health, and the assessment methods of nerve dysfunctions are addressed in this paper. Those methods are linked into a logical way of assessing effects of hand-arm vibration on human. Finally, the current activities and achievements in this work are briefly summarised.

• 한국안전학회지
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• 제24권5호
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• pp.6-12
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• 2009

This study performed an experiment for the danger of an electric shock in the human body, which is directly touched or approached to the exposure of buried metals in a leak caused by certain ground faults at a buried cable in street lamp. In the results of the experiment, the dangerous of electric shocks due to the earth specific resistance and wet and submersion of the earth surface represents a high level as the human body is directly touched to the buried metal at a leak point. In addition, it can be seen that the safety of the human body is influenced by the earth specific resistance, separated distance from buried metals, and shape of buried metals at around the leak point.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2001년도 추계학술대회논문집 II
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• pp.1361-1364
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• 2001

The recent national contract (Ecotechnopia 21) supported by the ministry of environment puts much significance on new issues for the assessment of human effects arising from vibration and noise exposed to human. This paper focuses only on hand-arm vibration since it has been a major problem in protecting vibration exposure to human. To set up a systematic way of assessing adverse effects of hand-arm vibration, surveys were made on recent international standards and researches related to hand-arm vibration. The measurement and evaluation methods of hand-arm transmitted vibration, the relationship between vibration exposure and effects on health, and the assessment methods of nerve dysfunctions are addressed in this paper. Those methods are linked into a logical way of assessing effects of hand-arm vibration on human. Finally, the current activities and achievements in this work are briefly summarised.

• 한국산업보건학회지
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• 제28권4호
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• pp.393-405
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• 2018

Objective: This study examines the types of hazardous factors in the working environment and the time-trend for their exposure levels over 10 years (2007 to 2016). Study Design and Method: The types of hazardous factors and exposure levels were drawn from the 19 measurement reports on the working environment over 10 years at a shock absorber manufacturing facility. Risk assessment of the types of factors and time-trend of exposure levels were evaluated using the factors and exposure levels. Results: A total of 34 hazardous factors were evaluated. The types were noise, 15 organic compounds, seven kinds of acid sand alkalis, eight kinds of heavy metals, and three other compounds. Special management materials used were nickel, hexavalent chrome, and sulfuric acid. Human carcinogens (1A) used were trichloroethylene, nickel, and sulfuric acid. There were six types of substances belonging to the IARC's 2B (body carcinogens) classification or higher, including, methyl isobutyl ketone, ethyl benzene, and trichloroethylene. No detection was found for 627 out of the 2065 total measurements in 19 exposure survey reports, representing 30.4%. Organic solvents, acid and alkali products, and heavy metals showed continuous low exposure concentrations. Noise, welding fumes, and the evaluation of mixed solvents show a gradual decrease in geometric mean and maximum over the time-trend of 10 years. Conclusions: In the case of a shock absorber manufacturing facility, the hazardous factors of noise and the evaluation of mixed solvents still indicate high concentrations exceeding the exposure limits and necessitate reduction studies. These two factors and welding fumes showed a continuous decrease in their ten-year tendency. Organic compounds, acids/alkalis, and heavy metals were managed smoothly in a work environment of continuous low concentrations.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2001년도 추계학술대회논문집 I
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• pp.455-458
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• 2001

In this paper, ISO2631-1(1997) was used to assess the vibration and shock transmitted by train seat with respect to possible effects on human health. Evaluations have been performed on the seat acceleration measured in two type of train, Saemaulho and Mugunghwaho. For each train, limiting daily exposure durations were estimated by comparing the frequency weighted root mean square(i.e., r.m.s) acceleration and the vibration dose values(i.e., VDV), calculated according to ISO2631-1(1997) with exposure limits, health guidance caution zones.

• Genomics & Informatics
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• 제8권1호
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• pp.34-40
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• 2010

Radiofrequency (RF) radiation might induce the transcription of a certain set of genes as other physical stresses like ionizing radiation and UV. To observe transcriptional changes upon RF radiation, we exposed WI-38, human lung fibroblast cell to 1763 MHz of mobile phone RF radiation at 60 W/kg of specific absorption rate (SAR) for 24h with or without heat control. There were no significant changes in cell numbers and morphology after exposure to RF radiation. Using quantitative RT-PCR, we checked the expression of three heat shock protein (HSP) (HSPA1A, HSPA6 and HSP105) and seven stress-related genes (TNFRSF11B, FGF2, TGFB2, ITGA2, BRIP1, EXO1, and MCM10) in RF only and RF/HS groups of RF-exposed cells. The expressions of three heat shock proteins and seven stress-related genes were selectively changed only in RF/HS groups. Based on the expression of ten genes, we could classify thermal and non-thermal effect of RF-exposure, which genes can be used as biomarkers for RF radiation exposure.

• Mass Spectrometry Letters
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• 제7권1호
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• pp.1-11
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• 2016

Various efforts have been developed to improve sample preparation steps, which strongly depend on hands-on processes for accurate and sensitive quantitative proteome analysis. In this study, we carried out heating the sample prior to trypsin digestion using an instrument to improve the tryptic digestion process. The heat shock generated by the system efficiently denatured proteins in the sample and increased the reproducibility in quantitative proteomics based on peptide abundance measurements. To demonstrate the effectiveness of the protocol, three cell lines (A human lung cancer cell line (A549), a human embryonic kidney cell line (HEK293T), and a human colorectal cancer cell line (HCT-116)) were selected and the effect of heat shock was compared to that of normal tryptic digestion processes. The tryptic digests were desalted and analysed by LC-MS/MS, the results showed 57 and 36% increase in the number of identified unique peptides and proteins, respectively, than conventional digestion. Heat shock treated samples showed higher numbers of shorter peptides and peptides with low inter-sample variation among triplicate runs. Quantitative LC-MS/MS analysis of heat shock treated sample yielded peptides with smaller relative error percentage for the triplicate run when the peak areas were compared. Exposure of heat-shock to proteomic samples prior to proteolysis in conventional digestion process can increase the digestion efficiency of trypsin resulting in production of increased number of peptides eventually leading to higher proteome coverage.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2000년도 추계학술대회논문집
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• pp.687-691
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• 2000

This paper reviews recent international standards related to human-related vibration and compares them to KS standards. This comparison and analysis reveals that the current direction and activity in ISO is in progress and presents logical ways of updating Korean standards in the future. Finally, the current activity of upgrading Korean standards in the Korean TC 108/SC 4 is introduced.