• Bioinformatics and Biosystems
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• 제1권1호
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• pp.82-87
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• 2006

현재 가장 많이 사용되는 단백질 구조 예측 방법은 비교 모델링 (comparative modeling) 방법이다. 비교 모델링 방법에서의 정확도를 높이기 위해서는 alignment의 정확도 역시 매우 필수적으로 필요하다. 비교 모델링 과정 중의 fold-recognition 단계에서 alignment의 정확도에 의해 template을 고르는 방법은 단지 가장 비슷한 template을 선택하는 방법에 비해 주목을 받지 못하고 있다. 최근에는 두 가지의 alignment에 사이의 shift 정보를 바탕으로 한 shift score라는 수치가 alignment의 성능을 표현하기 위해서 개발되었다. 우리는 더 정확한 구조 예측의 첫걸음이 될 수 있는 shift score를 예측하는 방법을 개발하였다. Shift score를 예측하기 위해 support vector regression (SVR)이 사용되었다. 사전에 구축된 라이브러리 안의 길이가 n 인 template과 구조를 알고 싶은 query 단백질 사이의 alignment는 n+2 차원의 input 벡터로 변환된다. Structural alignment가 가장 좋은 alignment로 가정되었고 SVR은 query 단백질과 template 단백질의 structural alignment과 profile-profile alignment 사이의 shift score를 예측하도록 training 되었다. 예측 정확도는 Pearson 상관계수로 측정되었다. Training 된 SVR은 실제의 shift score와 예측된 shift score 사이에 0.80의 Pearson 상관계수를 갖는 정도로 예측하였다.

• 문화기술의 융합
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• 제6권4호
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• pp.323-329
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• 2020

본 연구의 목적은 병원근무 여성 간호사의 우울 정도를 확인하고, 순환 교대근무와 수면의 질이 우울에 미치는 영향을 규명하기 위한 것이다. 연구대상자는 서울지역 2개 대학병원에 근무하는 총 295명의 간호사로 수집된 자료는 기술통계 및 다중회귀분석을 이용하여 분석하였다. 연구결과 참여자의 71.2%가 우울한 것으로 응답했으며(CES-D 총점 ≥ 16), 간호사 우울의 유의한 영향요인으로는 수면의 질, 순환 교대근무, 근무기간(1-2.9년, 10년 이상)으로 나타났다. 본 연구결과를 바탕으로 여성 간호사들의 우울을 감소시키기 위해서는 수면의 질과 순환 교대근무의 부정적 영향을 개선 시킬 수 있는 중재가 마련되어야 할 것으로 고려된다.

• 품질경영학회지
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• 제46권2호
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• pp.193-210
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• 2018

Purpose: The purpose of this study is to escape from the existing defense quality policy focused on government-led quality assurance for mass-produced items and to secure quality reliability of weapon systems through a defense quality policy paradigm shift based on designing a verification systems anchored on reliability through the enhancement of military supply quality control in the development stage, the enhancement of quality responsibility of the manufacturing contractor and other methods. Methods: For the shift to the quality-based defense quality policy, the status and the problems of the status quo are analyzed and the direction of future defense quality policy is suggested based on literature review of the concept of reliability and reliability in the field of defense, on case studies of global corporations and their quality policies, on the background on quality assurance in defense, and on case studies of quality policies in other government organizations, Results: Based on the case studies of quality policies in global corporations and other government agencies, the importance of preventive quality control from the early development stages, quality control based on the reliability of the materials and parts, and shift of the quality policy to a certification system to achieve these objectives were highlighted. Conclusion: To secure reliability of weapon system quality, the quality policy must be shifted to a system focused on reliability-based design and verification and there is a further need to enhance the operational efficiency and capacity of DTaQ based on studies and evaluation of weapon system reliability.

• 산업경영시스템학회지
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• 제40권1호
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• pp.165-172
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• 2017

Machines are physically or chemically degenerated by continuous usage. One of the results of this degeneration is the process mean shift. Under the process mean shift, production cost, failure cost and quality loss function cost are increasing continuously. Therefore a periodic preventive resetting the process is necessary. We suppose that the wear level is observable. In this case, process mean shift problem has similar characteristics to the maintenance policy model. In the previous studies, process mean shift problem has been studied in several fields such as 'Tool wear limit', 'Canning Process' and 'Quality Loss Function' separately or partially integrated form. This paper proposes an integrated cost model which involves production cost by the material, failure cost by the nonconforming items, quality loss function cost by the deviation between the quality characteristics from the target value and resetting the process cost. We expand this process mean shift problem a little more by dealing the process variance as a function, not a constant value. We suggested a multiplier function model to the process variance according to the analysis result with practical data. We adopted two-side specification to our model. The initial process mean is generally set somewhat above the lower specification. The objective function is total integrated costs per unit wear and independent variables are wear limit and initial setting process mean. The optimum is derived from numerical analysis because the integral form of the objective function is not possible. A numerical example is presented.

• Journal of Mechanical Science and Technology
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• 제14권12호
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• pp.1348-1357
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• 2000

• 한국생산제조학회지
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• 제20권5호
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• pp.639-645
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• 2011

Wheel-loader is a construction vehicle for uploading soil or sand into truck and transportation of materials, which requires large driving power and high rotational speed. To improve the working efficiency, the operator has to shift gears and control levers for bucket & boom simultaneously. Therefore, the automatic transmission has been introduced to enhance operator's convenience and enable effective operation. To develop the automatic transmission for the wheel-loader, technologies such as gears and a clutch-pack design and shift algorithm are required for improvement of shift quality. In this paper, the shift algorithm for the wheel-loader was developed and its shift pattern was analyzed. As the shift control is affected by the pressure profile for the clutch control, the shift quality depending on the pressure profile has been evaluated using experiment and simulation model analysis.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2008년도 추계학술대회 논문집
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• pp.361-364
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• 2008

In this paper, several fields for improving shift quality and mode conversion quality are presented and considered. For a series type hybrid vehicle, improving mode conversion quality is important because it changes its speed with its own motors. A parallel type hybrid vehicle usually has AT or AMT, and its motor and engine can work independently. Therefore, improving both of two qualities is equally important in this case. For a power split type hybrid vehicle, improving mode conversion quality is more important due to the existence of planetary gears which change vehicle's speed.

• 대한간호학회지
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• 제50권4호
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• pp.631-640
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• 2020

Purpose: This study aimed to examine premenstrual symptoms (PMS) of shift nurses and identify the association between PMS, sleep, and occupational stress. Methods: This study was conducted with a secondary data analysis that used data from the Shift Work Nurse's Health and Turnover study. The participants were 258 nurses who were working in shifts including night shifts. PMS, sleep patterns (sleep time and sleep time variability), sleep quality, and the occupational stress of each participant were measured using the Moos Menstrual Distress Questionnaire, a sleep diary, an actigraph, the Insomnia Severity Index, and the Korean Occupational Stress Scale, respectively. Data were analyzed using SPSS 23 and STATA 15.1 to obtain descriptive statistics, Pearson's correlation coefficients, multiple linear regression with generalized estimating equations (GEE) and Baron and Kenny's mediating analysis. Results: The average PMS score, average sleep time, average sleep time variability, average sleep quality score, and average occupational stress score of the participants was 53.95 ± 40.45, 7.52 ± 0.89 hours, 32.84 ± 8.43%, 12.34 ± 5.95, and 49.89 ± 8.98, respectively. A multiple linear regression analysis with GEE indicated that sleep time variability (B = 0.86, p = .001), and sleep quality (B = 2.36, p < .001) had negative effects on nurses' PMS. We also found that sleep quality had a complete mediating effect in the relationship between occupational stress and PMS. Conclusion: These findings indicate that both sleep time variability and sleep quality are important factors associated with PMS among shift work nurses. To improve shift nurses' PMS status, strategies are urgently needed to decrease sleep time variability and increase sleep quality.

• Journal of Korean Biological Nursing Science
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• 제21권4호
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• pp.266-274
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• 2019

Purpose: The aim of this research was to identify the mediating effect of sleep quality on the relationship between job stress and stress response of shift-working nurses. Methods: The participants in this study were 150 nurses who had more than 6 months of shift-working experience. A survey was conducted from May to June 2017 in a hospital in Gyeonggi-do, South Korea. The data were collected through self-report questionnaires. The collected data were analyzed using SAS 9.4 program. The analysis was based on Baron and Kenny's model to examine the mediating effects of sleep quality on the relationship between job stress and stress response of shift-working nurses. Results: In the first and second steps, job stress was identified as a significant predictor of sleep quality (β= .29, p= .001) and stress response (β = .24, p= .004). In the third step, sleep (B = .55, p< .001) was observed as a significant predictor of stress response, and the direct relationship between job stress and stress response was not significant (β= .07, p= .291). Sleep quality was found to exhibit complete mediating effect on the relationship between job stress and stress response. Conclusion: The results of this study suggest that strategies for managing the stress of shift-working nurses should include effective ways to ensure sleep quality.

• Journal of Power Electronics
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• 제12권4호
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• pp.664-676
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• 2012

A phase shift algorithm based on the closed-loop control of dc-link voltage implemented on a series active voltage quality regulator (AVQR) is proposed in this paper. To avoid pumping-up the dc-link voltage, a general phase shift compensation strategy is applied. The relationships among the operation variables are discussed in detail, which is very important for guiding the design of both the main circuit and the control system. Then on the basis of an investigation of the dc-link voltage pumping-up from viewpoint of the active power flow, a novel phase shift control method based on the closed-loop of the dc-link voltage is proposed. This method can adjust the phase of the output voltage gradually and automatically according to the dc-link voltage variation without introducing a phase jump. The effectiveness of the proposed strategy is verified through simulations of a single-phase 5kVA prototype and laboratory experiments on both a single-phase 5kVA and a three-phase 15kVA prototype.