• Journal of Fisheries and Marine Sciences Education
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• v.9 no.2
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• pp.167-178
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• 1997

It has been expected not only for crew but also for passengers to realize a ship whose rolling and other motions are small as much as possible. Restricting our consideration to the roll reduction, the conventional roll stabilization system, fins or anti-rolling tanks hve been utiized as the actuator. Excessive motions would interfere with the recreational activities of passengers on a cruise ship. Often more than half of the load of a containership is stowed above deck where it is subjected to large acclerations due to rolling. In some situations this may cause some internal damage to the contents of the containers; in more severe situations failure of the lashing can occur and containers may be lost over-board. Underdeck cargo in ordinary cargo ships and bulk commodities in colliers, ore ships and grain ships can shift if the motions become too severe. The purpose of this study is to concentrate on the additions. either internal or external to the hull, that reduce or otherwise improve the motion responses of the hull. It is assumed that the additions are such that their benefit to the motions of the ship outweights any impact on the ability of the ship to perform its assigned task. It is particularly challenging to obtain large improvements in the motion characteristics of existing ships that are being rebuilt or modified for some task not anticipated in their original design. Further the authors will statistically analyze the influence of ruder-roll-yaw coupling motion in the case of application of this advanced control method to various kinds of ship.

• Journal of Ginseng Research
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• v.36 no.3
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• pp.277-290
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• 2012

The metabolic profiles of Panax quinquefolius and its associated therapeutic values are critically affected by the repetitious steaming times. The times-dependent steaming effect of P. quinquefolius is not well-characterized and there is also no official guideline on its times of steaming. In this paper, a UPLC-Q-TOF-MS/MS method was developed for the qualitative profiling of multi-parametric metabolic changes of raw P. quinquefolius during the repetitious steaming process. Our method was successful in discriminating the differentially multi-steamed herbs. Meantime, the repetitious steaming-inducing chemical transformations in the preparation of black American ginseng (American ginseng that was subjected to 9 cycles of steaming treatment) were evaluated by this UPLC-Q-TOF-MS/MS based chemical profiling method. Under the optimized UPLC-Q-TOF-MS/MS conditions, 29 major ginsenosides were unambiguously identified and/or tentatively assigned in both raw and multi-steamed P. quinquefolius within 19 min, among them 18 ginsenosides were detected to be newly generated during the preparatory process of black American ginseng. The mechanisms involved were further deduced to be hydrolysis, dehydration, decarboxylation and addition reactions of the original ginsenosides in raw P. quinquefolius through analyzing mimic 9 cycles of steaming extracts of 14 pure reference ginsenosides. Our novel steaming times-dependent metabolic profiling approach represents the paradigm shift in the global quality control of multi-steamed P. quinquefolius products.

• Journal of Korean Society for Quality Management
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• v.45 no.3
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• pp.335-347
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• 2017

Purpose: Defense government agencies in the world continuously try to improve operational efficiency in government quality assurance activities. The purpose of this paper is to propose some suggestions to enhance efficiency of government quality assurance (GQA) activities based on the analysis of the current quality assurance methods of advanced foreign agencies such as DCMA and NATO. Methods: In order to propose new directions, reviews and analyses are executed. (1) Former research results in Korea for enhancing GQA are reviewed, and their limitations are addressed. (2) Updated policies and procedures of the US DCMA and NATO are reviewed and their advantages are presented. (3) Current GQA policies and procedures are contrasted with those of US DCMA and NATO. Results: Suggestions for efficient Korean GQA activities are given in several aspects: GQA paradigm shift, clarification of GQA methods, facility-wide GQA, risk management for suppliers, counterfeit mitigation policy, data collection and control. Conclusion: Reviews on the government quality assurance policies and procedures of DTaQ, DCMA, and NATO are executed and compared with each other. The results of this research are expected to be useful guidelines to improve GQA policies and procedures in Korea, making it possible to realize more efficient GQA activities in Korea.

• Toxicological Research
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• v.24 no.2
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• pp.151-159
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• 2008

Rhus verniciflua Stokes(RVS), one of traditional medicinal plants in Asia, was found to have pharmacological activities such as antioxidative and antiapoptotic effects, raising the possibility for the development of a novel class of anti-cancer drugs. Thus, potential genotoxic effects of RVS in three short-term mutagenicity assays were investigated, which included the Ames assay, in vitro Chromosomal aberration test, and the in vivo Micronucleus assay. In Ames test, the addition of RVS water extracts at doses from 313 up to 5000 mg/plate induced an increase more than 2-fold over vehicle control in the number of revertant colonies in TA98 and TA1537 strains for detecting the frame-shift mutagens. The similar increase in reversion frequency was observed after the addition of RVS ethanol extracts. To assess clastogenic effect, in vitro chromosomal aberration test and in vivo micronucleus assay were performed using Chinese hamster lung cells and male ICR mice, respectively. Both water and ethanol extracts from RVS induced significant increases in the number of metaphases with structural aberrations mostly at concentrations showing the cell survival less than 60% as assessed by in vitro CA test. Also, there was a weak but statistically significant increase in number of micronucleated polychromatic erythrocytes(MNPCEs) in mice treated with water extract at 2000 mg/kg while ethanol extracts of RVS at doses of up to 2000 mg/kg did not induce any statistically significant changes in the incidence of MNPCEs. Therefore, our results lead to conclusion that RVS acts as a genotoxic material based on the available in vitro and in vivo results.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3061-3064
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• 2012

Aim: An epidemiological shift has resulted in increase in the prevalence of non-communicable diseases (NCD). Unlike other NCDs which are easily and definitely preventable, the knowledge of cancer prevention is still limited at present. Various aetiological factors are difficult to control since those are habit forming. Hence an available remedy remains its secondary and tertiary prevention for which appropriate planning is of paramount importance. Evidence based planning requires careful analysis of data with a view to prioritize various cancers. Keeping in view the fact that the adaptation of smoking free status in Chandigarh city might have a far reaching positive effect on the cancer related morbidity of the people, the following study was undertaken to provide base line data to be used for future comparisons. Methods: The registers maintained in the Department of Radiotherapy were checked and those belonging to the years 1999 to 2009 were utilized to analyze the cancer morbidity in respect to age, sex, and year of presentation to health care facility. Results: A total of 4,600 cancer patients (males=2276, females=2324) demonstrated a gradual increase in the number of cancer cases from 150 in the year 1999 to 783 in the year 2009. The most common cancers amongst males were cancer of gastro-intestinal tract (GIT) and lung (including larynx) constituting 37.3% and 27.1% of the total, respectively. In females these were cancers of breast and cervix representing 33.3% & 17.6% of total cancer cases, respectively, and lung cancer constituted 5.3%. The maximum cases of bone cancer (53.8% of all bone cancers) were observed amongst children aged less than 20 years and lung cancer (48.2% of all lung cancers) among the elderly aged 60-69 years. The.

• BMB Reports
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• v.38 no.4
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• pp.474-480
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• 2005

Curcumin, a major active component of turmeric, has been identified as an inhibitor of the transcriptional activity of activator protein-1 (AP-1). Recently, it was also found that curcumin and synthetic curcumin derivatives can inhibit the binding of Jun-Fos, which are the members of the AP-1 family, to DNA. However, the mechanism of this inhibition by curcumin and its derivatives was not disclosed. Since the binding of Jun-Fos dimer to DNA can be modulated by redox control involving conserved cysteine residues, we studied whether curcumin and its derivatives inhibit Jun-Fos DNA binding activity via these residues. However, the inhibitory mechanism of curcumin and its derivatives, unlike that of other Jun-Fos inhibitors, was found to be independent of these conserved cysteine residues. In addition, we investigated whether curcumin derivatives can inhibit AP-1 transcriptional activity in vivo using a luciferase assay. We found that, among the curcumin derivatives examined, only inhibitors shown to inhibit the binding of Jun-Fos to DNA by Electrophoretic Mobility Shift Assay (EMSA) inhibited AP-1 transcriptional activity in vivo. Moreover, RT-PCR revealed that curcumin derivatives, like curcumin, downregulated c-jun mRNA in JB6 cells. These results suggest that the suppression of the formation of DNA-Jun-Fos complex is the main cause of reduced AP-1 transcriptional activity by curcuminoids, and that EMSA is a suitable tool for identifying inhibitors of transcriptional activation.

• Asian Journal for Public Opinion Research
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• v.5 no.1
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• pp.41-62
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• 2017

The political reformation in Indonesia is a determinant factor of the change in political communications and the roles of media. Currently, the political elites need media support, since it contextually has a significant role. Whoever has a good relationship with the media, will be loved by the public. On the other hand, the media also have a vested interest in the elite in running businesses and building the power of industry. Policies and capital pose a challenge to maintaining the continuity of the media. Independence and control of media are at stake, when the interests of the media and the elite collaborate with each other and then build a benefit on both sides. Meanwhile, the role of social media also cannot be neglected. The Indonesian political communication system is characterized by the presence of social media in a pseudo-relationship between the elite and the public. This paper tries to explain the growing trends of research in the academic environment and the research trends in political practice in Indonesia after the occurrence of post-reformation era in legislative and executive elections. The method used is the meta-analysis of research outcomes of university (dissertations) and secondary data sources. Data processing is done by meta-analysis of secondary data. The results of meta-analysis research indicate that, the objective conditions, in Indonesia, especially the political conditions, stimulate new spaces in communication research. The study of political communication becomes dominant in the academic environment. In addition, communication research is also characterized by a shift from the linear perspective (positivistic paradigm) to the interactive perspective (naturalistic paradigm). On the other hand, the development of politic and governance situations in Indonesia has prompted the establishment of polling agencies that help citizens understand the maps of political power and candidates in general elections and regional head elections.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38A no.3
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• pp.217-223
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• 2013

A digital retrodirective antenna system is easy to modify and upgrade because it can control the phase information of the output signal toward opposite direction to input signal without a priori knowledge of the arrival direction. Due to this advantage, it is possible to perform fast beam tracking. In this paper, a design digital retrosirective array antenna system according to the number of antenna array by using only one digital PLL which finds angle of delayed phase and we test BER performance of this system. When we transmit data at actual communication system, the data modulated onto carrier frequency in order to shift spectrum from base band to another band. So we simulate system considering carrier frequency according to the number of antenna array. As a result, carrier frequency has no impact on the performance.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.662-671
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• 2020

It is crucial to manage and maintain the geodetic reference coordinates of GNSS continuously operating reference stations (CORSs) in consideration of their fundamental roles in geodetic control and positioning navigation infrastructure. Earthquake-induced crustal displacement directly impacts the reference coordinates, so such events should be promptly detected, and appropriate action should be made to maintain the target accuracy, including update of the geodetic coordinates. To this end, this paper deals with online schemes for the detection of persistent shifts in the coordinate time-series produced by an automatic GNSS processing system. Algorithms were implemented to test filtered results, such as hypothesis tests of the innovation sequence of a Kalman filter and a cumulative sum (CUSUM) test. The results were assessed by the time-series of coordinates of 14 CORS for two years, including the 2011 Tohoku earthquake. The results show that the global hypothesis test is practical for detecting abrupt jumps, whereas CUSUM is effective for identifying persistent shifts.

• Journal of Surface Science and Engineering
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• v.47 no.4
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• pp.204-209
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• 2014

The electrodeposition of ZnO nanorods was performed on ITO glass. The optimization of two process parameters (solution temperature and growth time) has been studied in order to control the orientation, morphology, density, and growth rate of ZnO nanorods. The structural and optical properties of ZnO nanorods were systematically investigated by using field-emission scanning electron microscopy, X-ray diffractometer, and photoluminescence. Commonly, the results of the structural property show that hexagonal ZnO nanorods with wurtzite crystal structures have a c-axis orientation, and higher intensity for the ZnO (002) diffraction peaks. Furthermore, the nanorods length increased with increasing both the solution temperature and the growth time. The results of the optical property show a strong UV (3.28 eV) peaks and a weak visible (1.9~2.4 eV) bands, the intensity of UV peaks was increased with increasing both the solution temperature and the growth time. Especially, the UV peak for growth of nanorods at $75^{\circ}C$ blue-shift than different temperatures.